Beatrice Aiuto, Simona Cirrincione, Maria Gabriella Giuffrida, Laura Cavallarin, Chiara Portesi, Andrea Mario Rossi, Giorgio Borreani, Giovanni Rolla, Massimo Geuna, Stefania Nicola, Anna Quinternetto, Lucrezia Alessi, Elena Saracco, Luisa Brussino, Cristina Lamberti
Alpha-gal syndrome (AGS) is a mammalian meat allergy associated with tick bites and specific IgE to the oligosaccharide galactose-α-1,3-galactose (α-gal). Recent studies have shown that 10-20% of AGS patients also react to the dairy proteins. Considering the already described role of the meat lipid fraction in AGS manifestations, the aim of this work has been to investigate whether the milk fat globule proteins (MFGPs) could be involved in AGS. The MFGPs are extracted and their recognition by the IgE of AGS patients is proved through immunoblotting experiments...
May 5, 2024: Molecular Nutrition & Food Research