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M A Palomino Garibay, C Revilla Monsalve, A Cárdenas Sánchez, A C Polanco Ponce, S Islas Andrade
Diabetes mellitus is a major cause of morbidity and mortality and it has been studied in relation to the organs that affects, and the reproduction system is not the exception. Scientists had developed experimental animal models to investigate the effects of diabetes using different substances being streptozotocin (STZ) the most effective. STZ is natural compound produced by the Streptomyces achromogenes that selectively destroys the beta cells of the pancreas breaking the DNA. It has been proved that equilibrated solutions of STZ stored at 6 degrees C, are very effective in inducing diabetes to several animal species such as rat, mouse and hamster...
October 1998: Ginecología y Obstetricia de México
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