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https://www.readbyqxmd.com/read/28448858/the-development-and-piloting-of-an-ehealth-breastfeeding-resource-targeting-fathers-and-partners-as-co-parents
#1
Jennifer Abbass-Dick, Fangli Xie, Jaymie Koroluk, Shelley Alcock Brillinger, Joanne Huizinga, Amber Newport, William M Goodman, Cindy-Lee Dennis
OBJECTIVE: Traditionally breastfeeding education programs target mothers solely. The objective of this study was to design and pilot test an interactive eHealth breastfeeding co-parenting resource developed to target both mothers and fathers. eHealth resources provide an accessible and engaging format on which to educate parents and assist them in meeting their breastfeeding goals. Best practices to design such resources are not currently known. DESIGN: A three phase pilot study was conducted...
April 18, 2017: Midwifery
https://www.readbyqxmd.com/read/28448590/significant-changes-in-circulating-microrna-by-dietary-supplementation-of-selenium-and-coenzyme-q10-in-healthy-elderly-males-a-subgroup-analysis-of-a-prospective-randomized-double-blind-placebo-controlled-trial-among-elderly-swedish-citizens
#2
Urban Alehagen, Peter Johansson, Jan Aaseth, Jan Alexander, Dick Wågsäter
BACKGROUND: Selenium and coenzyme Q10 is essential for important cellular functions. A low selenium intake is reported from many European countries, and the endogenous coenzyme Q10 production is decreasing in the body with increasing age. Supplementation with selenium and coenzyme Q10 in elderly have shown reduced cardiovascular mortality and reduced levels of markers of inflammation. However, microRNA analyses could give important information on the mechanisms behind the clinical effects of supplementation...
2017: PloS One
https://www.readbyqxmd.com/read/28447621/direct-involvement-of-androgen-receptor-in-oxytocin-gene-expression-possible-relevance-for-mood-disorders
#3
Dan Dai, Qiao-Chu Li, Qiong-Bin Zhu, Shao-Hua Hu, Rawien Balesar, Dick Swaab, Ai-Min Bao
Oxytocin (OXT), synthesized in the hypothalamic paraventricular nucleus (PVN) and then released into different brain areas, may play a crucial role in various behaviors and neuropsychiatric disorders, including depression. Testosterone has been proposed by clinical studies to have the opposite effect of oxytocin in these disorders. We began by studying, in the postmortem hypothalamus of fifteen patients with mood disorders and fifteen matched controls, the expression of OXT in the PVN by means of immunocytochemistry (ICC) and the co-localization of OXT and androgen receptor (AR) by means of double labeling ICC...
April 27, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28445659/adalimumab-plus-methotrexate-for-uveitis-in-juvenile-idiopathic-arthritis
#4
Athimalaipet V Ramanan, Andrew D Dick, Ashley P Jones, Andrew McKay, Paula R Williamson, Sandrine Compeyrot-Lacassagne, Ben Hardwick, Helen Hickey, Dyfrig Hughes, Patricia Woo, Diana Benton, Clive Edelsten, Michael W Beresford
Background Adalimumab, a fully human anti-tumor necrosis factor α monoclonal antibody, is effective in the treatment of juvenile idiopathic arthritis (JIA). We tested the efficacy of adalimumab in the treatment of JIA-associated uveitis. Methods In this multicenter, double-blind, randomized, placebo-controlled trial, we assessed the efficacy and safety of adalimumab in children and adolescents 2 years of age or older who had active JIA-associated uveitis. Patients who were taking a stable dose of methotrexate were randomly assigned in a 2:1 ratio to receive either adalimumab (at a dose of 20 mg or 40 mg, according to body weight) or placebo, administered subcutaneously every 2 weeks...
April 27, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28445163/annealing-of-au-ag-and-au-ag-alloy-nanoparticle-arrays-on-gaas-100-and-111-b
#5
Alexander M Whiticar, Erik K Mårtensson, Jesper Nygård, Kimberly A Dick, Jessica Bolinsson
Metal nanoparticles (NPs), in particular gold NPs, are often used in the fabrication process of semiconductor nanowires. Besides being able to induce the 1D crystallization of new material, it is highly beneficial if the NPs can be used to dictate the position and diameter of the final nanowire structure. To achieve well-defined NP arrays of varying diameter and pitch distances for nanowire growth, it is necessary to understand and control the effect that a pre-growth annealing process may have on the pre-defined NP arrays...
May 19, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28443275/integration-of-hiv-testing-into-maternal-newborn-and-child-health-weeks-for-improved-case-finding-and-linkage-to-prevention-of-mother-to-child-transmission-services-in-benue-state-nigeria
#6
Olusoji Akinleye, Gideon Dura, Arjan de Wagt, Abiola Davies, Dick Chamla
BACKGROUND: In Nigeria, maternal, newborn, and child health (MNCH) weeks are campaign-like events designed to accelerate progress toward Millennium Development Goals. The authors examined whether integrating HIV testing into MNCH weeks was feasible and could lead to increased case finding and linkage to prevention of mother-to-child transmission (PMTCT) services. METHODS: Pregnant women attending MNCH week during the first week of December 2014 in 13 local government areas in Benue State were provided with HIV tests and referrals to PMTCT services...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28440866/a-prospective-comparison-of-how-the-level-of-response-to-alcohol-and-impulsivity-relate-to-future-dsm-iv-alcohol-problems-in-the-coga-youth-panel
#7
Marc A Schuckit, Tom L Smith, George Danko, Robert Anthenelli, Lara Schoen, Mari Kawamura, John Kramer, Danielle M Dick, Zoe Neale, Samuel Kuperman, Vivia McCutcheon, Andrey P Anokhin, Victor Hesselbrock, Michie Hesselbrock, Kathleen Bucholz
BACKGROUND: Alcohol problems reflect both environmental and genetic characteristics that often operate through endophenotypes like low levels of response (low LRs) to alcohol and higher impulsivity. Relationships of these preexisting characteristics to alcohol problems have been studied, but few analyses have included both low LR and impulsivity in the same model. METHODS: We extracted prospective data from 1,028 participants in the Prospective Youth Sample of the Collaborative Study for the Genetics of Alcoholism (COGA)...
April 25, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28439620/development-of-an-optimal-filter-substrate-for-the-identification-of-small-microplastic-particles-in-food-by-micro-raman-spectroscopy
#8
Barbara E Oßmann, George Sarau, Sebastian W Schmitt, Heinrich Holtmannspötter, Silke H Christiansen, Wilhelm Dicke
When analysing microplastics in food, due to toxicological reasons it is important to achieve clear identification of particles down to a size of at least 1 μm. One reliable, optical analytical technique allowing this is micro-Raman spectroscopy. After isolation of particles via filtration, analysis is typically performed directly on the filter surface. In order to obtain high qualitative Raman spectra, the material of the membrane filters should not show any interference in terms of background and Raman signals during spectrum acquisition...
April 24, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28433116/foreword
#9
EDITORIAL
Michael J Aminoff, François Boller, Dick F Swaab
No abstract text is available yet for this article.
2017: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/28426968/map2-defines-a-pre-axonal-filtering-zone-to-regulate-kif1-versus-kif5-dependent-cargo-transport-in-sensory-neurons
#10
Laura F Gumy, Eugene A Katrukha, Ilya Grigoriev, Dick Jaarsma, Lukas C Kapitein, Anna Akhmanova, Casper C Hoogenraad
Polarized cargo transport is essential for neuronal function. However, the minimal basic components required for selective cargo sorting and distribution in neurons remain elusive. We found that in sensory neurons the axon initial segment is largely absent and that microtubule-associated protein 2 (MAP2) defines the cargo-filtering zone in the proximal axon. Here, MAP2 directs axonal cargo entry by coordinating the activities of molecular motors. We show that distinct kinesins differentially regulate cargo velocity: kinesin-3 drives fast axonal cargo trafficking, while kinesin-1 slows down axonal cargo transport...
April 19, 2017: Neuron
https://www.readbyqxmd.com/read/28426849/effect-of-adalimumab-on-visual-functioning-in-patients-with-noninfectious-intermediate-uveitis-posterior-uveitis-and-panuveitis-in-the-visual-1-and-visual-2-trials
#11
John Sheppard, Avani Joshi, Keith A Betts, Stacie Hudgens, Samir Tari, Naijun Chen, Martha Skup, Andrew D Dick
Importance: Adalimumab was recently approved for the treatment of noninfectious intermediate uveitis, posterior uveitis, and panuveitis. Objective: To assess the effect of adalimumab on the visual functioning and quality of life in patients with corticosteroid-dependent noninfectious intermediate uveitis, posterior uveitis, and panuveitis. Design: A post hoc analysis of clinical trials of adults with active (VISUAL-1) and inactive (VISUAL-2) noninfectious intermediate uveitis, posterior uveitis, and panuveitis was conducted in the United States, Canada, Europe, Israel, Australia, Latin America, and Japan...
April 20, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28424107/early-maturation-and-substance-use-across-adolescence-and-young-adulthood-a-longitudinal-study-of-finnish-twins
#12
Jeanne E Savage, Richard J Rose, Lea Pulkkinen, Karri Silventoinen, Tellervo Korhonen, Jaakko Kaprio, Nathan Gillespie, Danielle M Dick
Early maturation, indexed by pubertal development (PD), has been associated with earlier initiation and greater frequency of adolescent substance use, but this relationship may be biased by confounding factors and effects that change across development. Using a population-based Finnish twin sample (N = 3,632 individuals), we conducted twin modeling and multilevel structural equation modeling of the relationship between PD and substance use at ages 12-22. Shared environmental factors contributed to early PD and heavier substance use for females...
April 20, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28421185/changes-in-composition-of-the-gut-bacterial-microbiome-after-fecal-microbiota-transplantation-for-recurrent-clostridium-difficile-infection-in-a-pediatric-heart-transplant-patient
#13
Kyle L Flannigan, Taylor Rajbar, Andrew Moffat, Leanna S McKenzie, Frank Dicke, Kevin Rioux, Matthew L Workentine, Thomas J Louie, Simon A Hirota, Steven C Greenway
The microbiome is increasingly recognized as an important influence on human health and many of the comorbidities that affect patients after solid organ transplantation (SOT) have been shown to involve changes in gut bacterial populations. Thus, microbiome changes in an individual patient may have important health implications after SOT but this area remains understudied. We describe changes in the composition of the fecal microbiome from a pediatric heart transplant recipient before and >2.5 years after he underwent repeated fecal microbiota transplantation (FMT) for recurrent Clostridium difficile infection (CDI)...
2017: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28420673/a-single-bout-of-high-intensity-interval-training-reduces-awareness-of-subsequent-hypoglycemia-in-patients-with-type-1-diabetes
#14
Hanne M Rooijackers, Evita C Wiegers, Marinette van der Graaf, Dick H Thijssen, Roy P C Kessels, Cees J Tack, Bastiaan E de Galan
High-intensity interval training (HIIT) gains increasing popularity in patients with diabetes. HIIT acutely increases plasma lactate levels. This may be important, since administration of lactate during hypoglycemia suppresses symptoms and counterregulation, whilst preserving cognitive function. We tested the hypothesis that HIIT acutely reduces awareness of hypoglycemia and attenuates hypoglycemia-induced cognitive dysfunction. In a randomized crossover trial, patients with type 1 diabetes and normal awareness of hypoglycemia (NAH), patients with impaired awareness of hypoglycemia (IAH), and healthy participants (n=10 per group) underwent a hyperinsulinemic-hypoglycemic (2...
April 18, 2017: Diabetes
https://www.readbyqxmd.com/read/28419430/the-role-of-family-characteristics-for-students-academic-outcomes-a%C3%A2-person-centered-approach
#15
Isabelle Häfner, Barbara Flunger, Anna-Lena Dicke, Hanna Gaspard, Brigitte M Brisson, Benjamin Nagengast, Ulrich Trautwein
Using data from 1,571 ninth-grade students (Mage  = 14.62) from 82 academic track schools in Germany and their predominantly Caucasian middle-class parents, configurations of different family characteristics reported by parents were investigated. Latent profile analyses considering academic involvement, family interest, parents' self-concept, child's need for support, and parents' time and energy identified average, indifferent, motivated and engaged, motivated and disengaged, and involved families. Cross-sectional and longitudinal associations with students' motivational (self-concept, effort, and interest) and achievement outcomes (achievement test and grades) in math were analyzed...
April 17, 2017: Child Development
https://www.readbyqxmd.com/read/28418090/natural-mortality-and-cause-of-death-analysis-of-the-captive-chimpanzee-pan-troglodytes-a-35-year-review
#16
REVIEW
Hannah Laurence, Shyamesh Kumar, Michael A Owston, Robert E Lanford, Gene B Hubbard, Edward J Dick
We present the spontaneous causes of mortality for 137 chimpanzees (Pan troglodytes) over a 35-year period. A record review of the pathology database was performed and a primary cause of mortality was determined for each chimpanzee. The most common causes of mortality were as follows: cardiomyopathy (40% of all mortalities), stillbirth/abortion, acute myocardial necrosis, chimpanzee-induced trauma, amyloidosis, and pneumonia. Five morphologic diagnoses accounted for 61% of mortalities: cardiomyopathy, hemorrhage, acute myocardial necrosis, amyloidosis, and pneumonia...
April 18, 2017: Journal of Medical Primatology
https://www.readbyqxmd.com/read/28413602/do-sex-differences-in-ceoaes-and-2d-4d-ratios-reflect-androgen-exposure-a-study-in-women-with-complete-androgen-insensitivity-syndrome
#17
Judy van Hemmen, Peggy T Cohen-Kettenis, Thomas D Steensma, Dick J Veltman, Julie Bakker
BACKGROUND: Studies investigating the influence of perinatal hormone exposure on sexually differentiated traits would greatly benefit from biomarkers of these early hormone actions. Click-evoked otoacoustic emissions show sex differences that are thought to reflect differences in early androgen exposure. Women with complete androgen insensitivity syndrome (CAIS), who lack androgen action in the presence of XY-chromosomes, enabled us to study the effect of complete androgen inaction. The main goal was to investigate a possible link between click-evoked otoacoustic emissions and effective androgen exposure and, thus, whether this can be used as a biomarker...
2017: Biology of Sex Differences
https://www.readbyqxmd.com/read/28412613/intensified-emotion-perception-in-depression-differences-in-physiological-arousal-and-subjective-perceptions
#18
Sofia Wenzler, Marleen Hagen, Mika P Tarvainen, Marietheres Hilke, Naddy Ghirmai, Ann-Caitlin Huthmacher, Marco Trettin, Rolf van Dick, Andreas Reif, Viola Oertel-Knöchel
People suffering from depression perceive themselves and their surroundings as more negative than healthy ones. An explanation might be that depressed individuals experience negative information as more stressful than non-depressed subjects and, consequently, respond in an amplified manner on a subjective and physiological level. To test this proposition, we presented 41 patients with recurrent depressive episodes and 42 controls with stimuli from the International Affective Picture System split into three valence categories while different parameters of physiological arousal (e...
April 2, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28410717/greater-vertical-spot-spacing-to-improve-femtosecond-laser-capsulotomy-quality
#19
Tim Schultz, Stephanie C Joachim, Rozina Noristani, Wendell Scott, H Burkhard Dick
PURPOSE: To evaluate the effect of adapted capsulotomy laser settings on the cutting quality in femtosecond laser-assisted cataract surgery. SETTING: Ruhr-University Eye Clinic, Bochum, Germany. DESIGN: Prospective randomized case series. METHODS: Eyes were treated with 1 of 2 laser settings. In Group 1, the regular standard settings were used (incisional depth 600 μm, pulse energy 4 μJ, horizontal spot spacing 5 μm, vertical spot spacing 10 μm, treatment time 1...
March 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28410716/clinical-performance-in-continuous-curvilinear-capsulorhexis-creation-supported-by-a-digital-image-guidance-system
#20
Yesim Haeussler-Sinangin, Dorothee Dahlhoff, Tim Schultz, H Burkhard Dick
PURPOSE: To test whether a default capsulorhexis diameter could be attained more precisely when manual continuous curvilinear capsulorhexis (CCC) creation was supported by a biomorphological detection unit. SETTING: Ruhr University Eye Hospital, Bochum, Germany. DESIGN: Prospective interventional study. METHODS: Patients were assigned to either of 2 groups. In the first group, a digital image system was applied to guide capsulorhexis...
March 2017: Journal of Cataract and Refractive Surgery
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