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https://www.readbyqxmd.com/read/29650313/a-novel-feature-extraction-technique-for-pulmonary-sound-analysis-based-on-emd
#1
Ashok Mondal, Poulami Banerjee, Hong Tang
BACKGROUND AND OBJECTIVE: The stethoscope based auscultation technique is a primary diagnostic tool for chest sound analysis. However, the performance of this method is limited due to its dependency on physicians experience, knowledge and also clarity of the signal. To overcome this problem we need an automated computer-aided diagnostic system that will be competent in noisy environment. In this paper, a novel feature extraction technique is introduced for discriminating various pulmonary dysfunctions in an automated way based on pattern recognition algorithms...
June 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29588643/integrated-care-to-address-the-physical-health-needs-of-people-with-severe-mental-illness-a-mapping-review-of-the-recent-evidence-on-barriers-facilitators-and-evaluations
#2
Mark Rodgers, Jane Dalton, Melissa Harden, Andrew Street, Gillian Parker, Alison Eastwood
People with mental health conditions have a lower life expectancy and poorer physical health outcomes than the general population. Evidence suggests this is due to a combination of clinical risk factors, socioeconomic factors, and health system factors, notably a lack of integration when care is required across service settings. Several recent reports have looked at ways to better integrate physical and mental health care for people with severe mental illness (SMI). We built on these by conducting a mapping review that looked for the most recent evidence and service models in this area...
January 25, 2018: International Journal of Integrated Care
https://www.readbyqxmd.com/read/29571628/differences-in-%C3%AE-crystallin-isomerization-reveal-the-activity-of-protein-isoaspartyl-methyltransferase-pimt-in-the-nucleus-and-cortex-of-human-lenses
#3
Yana A Lyon, Georgette M Sabbah, Ryan R Julian
Although it is well-known that protein turnover essentially stops in mature lens fiber cells, mapping out the ensuing protein degradation and its effects on lens function over time remains challenging. In particular, isomerization is a common, spontaneous post-translational modification that occurs over long timescales and generates products invisible to most analytical methods. Nevertheless, isomerization can significantly impact protein structure, function, and solubility, which are all necessary to maintain clarity and proper refractive index within the lens...
March 20, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29548894/spiritual-distress-within-inpatient-settings-a-scoping-review-of-patient-and-family-experiences
#4
REVIEW
Amanda L Roze des Ordons, Tasnim Sinuff, Henry T Stelfox, Jane Kondejewski, Shane Sinclair
CONTEXT: Spiritual distress contributes to patient and family experiences of care. OBJECTIVES: To map the literature on how seriously ill patients and their family members experience spiritual distress within inpatient settings. METHODS: Our scoping review included 4 databases using search terms 'existential' or 'spiritual' combined with 'angst', 'anxiety', 'distress', 'stress' or 'anguish'. We included original research describing experiences of spiritual distress among adult patients or family members within inpatient settings and instrument validation studies...
March 14, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29514402/how-fundamental-aspects-of-nursing-care-are-defined-in-the-literature-a-scoping-review
#5
Rebecca Feo, Alison Kitson, Tiffany Conroy
AIMS AND OBJECTIVES: To investigate how fundamental aspects of nursing care have been defined in the literature from 2010-2016. BACKGROUND: A 2010 narrative review of nursing texts identified little consensus on what constitutes the fundamental aspects of nursing care. Since then there has been a proliferation of policies, strategic frameworks and research teams dedicated to investigating such care. It is unclear whether this increased activity has led to greater conceptual clarity...
March 7, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29505486/adapting-the-consolidated-framework-for-implementation-research-to-create-organizational-readiness-and-implementation-tools-for-project-echo
#6
Eva Serhal, Amanda Arena, Sanjeev Sockalingam, Linda Mohri, Allison Crawford
The Project Extension for Community Healthcare Outcomes (ECHO) model expands primary care provider (PCP) capacity to manage complex diseases by sharing knowledge, disseminating best practices, and building a community of practice. The model has expanded rapidly, with over 140 ECHO projects currently established globally. We have used validated implementation frameworks, such as Damschroder's (2009) Consolidated Framework for Implementation Research (CFIR) and Proctor's (2011) taxonomy of implementation outcomes, combined with implementation experience to (1) create a set of questions to assess organizational readiness and suitability of the ECHO model and (2) provide those who have determined ECHO is the correct model with a checklist to support successful implementation...
March 1, 2018: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/29386133/organization-of-valence-encoding-and-projection-defined-neurons-in-the-basolateral-amygdala
#7
Anna Beyeler, Chia-Jung Chang, Margaux Silvestre, Clémentine Lévêque, Praneeth Namburi, Craig P Wildes, Kay M Tye
The basolateral amygdala (BLA) mediates associative learning for both fear and reward. Accumulating evidence supports the notion that different BLA projections distinctly alter motivated behavior, including projections to the nucleus accumbens (NAc), medial aspect of the central amygdala (CeM), and ventral hippocampus (vHPC). Although there is consensus regarding the existence of distinct subsets of BLA neurons encoding positive or negative valence, controversy remains regarding the anatomical arrangement of these populations...
January 23, 2018: Cell Reports
https://www.readbyqxmd.com/read/29364117/improved-visualization-of-gastrointestinal-slow-wave-propagation-using-a-novel-wavefront-orientation-interpolation-technique
#8
Terence P Mayne, Niranchan Paskaranandavadivel, Jonathan C Erickson, Gregory OGrady, Leo K Cheng, Timothy R Angeli
OBJECTIVE: High-resolution mapping of gastrointestinal (GI) slow waves is a valuable technique for research and clinical applications. Interpretation of high-resolution GI mapping data relies on animations of slow wave propagation, but current methods remain as rudimentary, pixelated electrode activation animations. This study aimed to develop improved methods of visualizing high-resolution slow wave recordings that increases ease of interpretation. METHODS: The novel method of "wavefront-orientation" interpolation was created to account for the planar movement of the slow wave wavefront, negate any need for distance calculations, remain robust in atypical wavefronts (i...
February 2018: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/29248498/towards-a-neuro-computational-account-of-prism-adaptation
#9
Pierre Petitet, Jill X O'Reilly, Jacinta O'Shea
Prism adaptation has a long history as an experimental paradigm used to investigate the functional and neural processes that underlie sensorimotor control. In the neuropsychology literature, prism adaptation behaviour is typically explained by reference to a traditional cognitive psychology framework that distinguishes putative functions, such as 'strategic control' versus 'spatial realignment'. This theoretical framework lacks conceptual clarity, quantitative precision and explanatory power. Here, we advocate for an alternative computational framework that offers several advantages: 1) an algorithmic explanatory account of the computations and operations that drive behaviour; 2) expressed in quantitative mathematical terms; 3) embedded within a principled theoretical framework (Bayesian decision theory, state-space modelling); 4) that offers a means to generate and test quantitative behavioural predictions...
December 14, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29236560/examining-the-nature-of-interprofessional-practice-an-initial-framework-validation-and-creation-of-the-interprofessional-activity-classification-tool-interpact
#10
Andreas Xyrichis, Scott Reeves, Merrick Zwarenstein
The practice of, and research on interprofessional working in healthcare, commonly referred to as teamwork, has been growing rapidly. This has attracted international policy support flowing from the growing belief that patient safety and quality of care can only be achieved through the collective effort of the multiple professionals caring for a given patient. Despite the increasing policy support, the evidence for effectiveness lags behind: while there are supporting analytic epidemiological studies, few reliable intervention studies have been published and so we have yet to confirm a causal link...
December 13, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29196268/developing-3d-microscopy-with-clarity-on-human-brain-tissue-towards-a-tool-for-informing-and-validating-mri-based-histology
#11
Markus Morawski, Evgeniya Kirilina, Nico Scherf, Carsten Jäger, Katja Reimann, Robert Trampel, Filippos Gavriilidis, Stefan Geyer, Bernd Biedermann, Thomas Arendt, Nikolaus Weiskopf
Recent breakthroughs in magnetic resonance imaging (MRI) enabled quantitative relaxometry and diffusion-weighted imaging with sub-millimeter resolution. Combined with biophysical models of MR contrast the emerging methods promise in vivo mapping of cyto- and myelo-architectonics, i.e., in vivo histology using MRI (hMRI) in humans. The hMRI methods require histological reference data for model building and validation. This is currently provided by MRI on post mortem human brain tissue in combination with classical histology on sections...
November 28, 2017: NeuroImage
https://www.readbyqxmd.com/read/29194334/creativity-and-innovation-in-health-care-tapping-into-organizational-enablers-through-human-centered-design
#12
Christi Dining Zuber, Louise Moody
There is an increasing drive in health care for creativity and innovation to tackle key health challenges, improve quality and access, and reduce harm and costs. Human-centered design (HCD) is a potential approach to achieving organizational innovation. However, research suggests the nursing workforce feels unsupported to take the risks needed for innovation, and leaders may not understand the conditions required to fully support them. The aim of this study was to identify enabling conditions that support frontline nurses in their attempts to behave as champions of innovation and change...
January 2018: Nursing Administration Quarterly
https://www.readbyqxmd.com/read/29171994/hippocampal-stratum-radiatum-lacunosum-and-moleculare-sparing-in-mild-cognitive-impairment
#13
Li Su, Lawrence Hayes, Soteris Soteriades, Guy Williams, Susannah A E Brain, Michael J Firbank, Giulia Longoni, Robert J Arnold, James B Rowe, John T O'Brien
BACKGROUND: Alzheimer's disease (AD) is associated with atrophy in entorhinal cortex (ERC), the hippocampus, and its subfields Cornu Ammonis 1 (CA1) and subiculum, which predict conversion from mild cognitive impairment (MCI) to clinical AD. The stratum radiatum, lacunosum, and moleculare (SRLM) are also important gateways involving ERC and CA1, which are affected by early AD pathology. OBJECTIVE: To assess whether the SRLM is affected in MCI and AD. METHODS: In this proof-of-concept study, 27 controls, 13 subjects with AD, and 22 with MCI underwent 3T MRI...
2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29138689/clarifying-sub-genomic-positions-of-qtls-for-flowering-habit-and-fruit-quality-in-u-s-strawberry-fragaria-%C3%A3-ananassa-breeding-populations-using-pedigree-based-qtl-analysis
#14
Sujeet Verma, Jason D Zurn, Natalia Salinas, Megan M Mathey, Beatrice Denoyes, James F Hancock, Chad E Finn, Nahla V Bassil, Vance M Whitaker
The cultivated strawberry ( Fragaria × ananassa ) is consumed worldwide for its flavor and nutritional benefits. Genetic analysis of commercially important traits in strawberry are important for the development of breeding methods and tools for this species. Although several quantitative trait loci (QTL) have been previously detected for fruit quality and flowering traits using low-density genetic maps, clarity on the sub-genomic locations of these QTLs was missing. Recent discoveries in allo-octoploid strawberry genomics led to the development of the IStraw90 single-nucleotide polymorphism (SNP) array, enabling high-density genetic maps and finer resolution QTL analysis...
2017: Horticulture Research
https://www.readbyqxmd.com/read/29138191/evaluation-of-guidelines-regarding-surgical-treatment-of-breast-cancer-using-the-agree-instrument-a-systematic-review
#15
Xin Lei, Fengtao Liu, Shuying Luo, Ya Sun, Liling Zhu, Fengxi Su, Kai Chen, Shunrong Li
OBJECTIVES: Many clinical practice guidelines and consensus statements (CPGs/consensus statements) have been developed for the surgical treatments for breast cancer. This study aims to evaluate the quality of these CPGs/consensus statements. METHODS: We systematically searched the PubMed and EMBASE databases, as well as four guideline repositories, to identify CPGs and consensus statements regarding surgical treatments for breast cancer between January 2009 and December 2016...
November 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29076013/hospital-staff-views-of-prescribing-and-discharge-communication-before-and-after-electronic-prescribing-system-implementation
#16
Pamela Ruth Mills, Anita Elaine Weidmann, Derek Stewart
Background Electronic prescribing system implementation is recommended to improve patient safety and general practitioner's discharge information communication. There is a paucity of information about hospital staff perspectives before and after system implementation. Objective To explore hospital staff views regarding prescribing and discharge communication systems before and after hospital electronic prescribing and medicines administration (HEPMA) system implementation. Setting A 560 bed United Kingdom district general hospital...
December 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29038182/protocol-for-a-scoping-review-to-identify-and-map-the-global-health-personnel-considered-skilled-attendants-at-birth-in-low-and-middle-income-countries-between-2000-and-2015
#17
Amy J Hobbs, Ann-Beth Moller, Liliana Carvajal-Aguirre, Agbessi Amouzou, Doris Chou, Lale Say
INTRODUCTION: Despite progress towards the Millennium Development Goals (MDG), maternal mortality remains high in countries where there are shortages of skilled personnel able to manage and provide quality care during pregnancy and childbirth. The 'percentage of births attended by skilled health personnel' (SAB, skilled attendants at birth) was a key indicator for tracking progress since the MDGs and is part of the Sustainable Development Goal agenda. However, due to contextual differences between and within countries on the definition of SAB, a lack of clarity exists around the training, competencies, and skills they are qualified to perform...
October 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29028141/mapping-trends-in-the-concept-of-nurse-rounding-a-bibliometric-analysis-and-research-agenda
#18
Marie Hutchinson, Mary Higson, Debra Jackson
AIMS: Examine the growth and diffusion of research on the concept of nurse rounding and provide definitional clarity on forms of nurse rounding. METHODS: Bibliometric and content analysis of primary research on nurse rounding were used to map development of the field. Manuscripts were identified from a keyword search of MEDLINE, CINAHL, and PsycINFO databases for the period 2000 to 2015. Titles, country of origin, and year of publication along with details on the characteristics and sample of each study were coded on a database...
December 2017: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/28974248/toward-criteria-for-pragmatic-measurement-in-implementation-research-and-practice-a-stakeholder-driven-approach-using-concept-mapping
#19
Byron J Powell, Cameo F Stanick, Heather M Halko, Caitlin N Dorsey, Bryan J Weiner, Melanie A Barwick, Laura J Damschroder, Michel Wensing, Luke Wolfenden, Cara C Lewis
BACKGROUND: Advancing implementation research and practice requires valid and reliable measures of implementation determinants, mechanisms, processes, strategies, and outcomes. However, researchers and implementation stakeholders are unlikely to use measures if they are not also pragmatic. The purpose of this study was to establish a stakeholder-driven conceptualization of the domains that comprise the pragmatic measure construct. It built upon a systematic review of the literature and semi-structured stakeholder interviews that generated 47 criteria for pragmatic measures, and aimed to further refine that set of criteria by identifying conceptually distinct categories of the pragmatic measure construct and providing quantitative ratings of the criteria's clarity and importance...
October 3, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28972922/transmission-kikuchi-diffraction-versus-electron-back-scattering-diffraction-a-case-study-on-an-electron-transparent-cross-section-of-twip-steel
#20
Azdiar A Gazder, Khalil I Elkhodary, Mitchell J B Nancarrow, Ahmed A Saleh
The present case study compares transmission Kikuchi diffraction (TKD) with electron back-scattering diffraction (EBSD) on the same area of an electron transparent cross-section of a twinning induced plasticity steel. While TKD expectedly provides better clarity of internal defect substructures in the band contrast map, EBSD returns orientation data that approaches the quality of the TKD map. This was rationalised by Monte Carlo simulations of the electron energy spreads, which showed that due to the geometry-based compromises associated with adapting a conventional EBSD detector (which is off-axis with respect to the incident electron beam) to TKD, a broadening in the electron energy distribution of the forward-scattered electrons collected on the detector phosphor screen, is unavoidable...
December 2017: Micron: the International Research and Review Journal for Microscopy
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