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"BOSWELLIA SERRATA"

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https://www.readbyqxmd.com/read/28278495/antioxidant-supplements-and-gastrointestinal-diseases-a-critical-appraisal
#1
Islam Khan, Sue E Samson, Ashok Kumar Grover
The gastrointestinal tract digests and absorbs dietary nutrients; protects the body against physical and chemical damage from contents in its lumen; provides immunity against external antigens and keeps an optimum environment for the gut microbiota. These functions cannot be performed normally in several diseases of which the following are discussed here: irritable bowel syndrome, inflammatory bowel disease which includes Crohn's disease and ulcerative colitis. Because these diseases are associated with oxidative stress, a host of antioxidant supplements are used for maintenance and recovery of the gut functions...
March 8, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/28245338/boswellia-serrata-resin-extract-alleviates-azoxymethane-aom-dextran-sodium-sulfate-dss-induced-colon-tumorigenesis
#2
Ya-Chun Chou, Joon Hyuk Suh, Yu Wang, Manoj Pahwa, Vladimir Badmeav, Chi-Tang Ho, Min-Hsiung Pan
SCOPE: Boswellia serrata (BS) resin is a popular dietary supplement for joint nourishment. In this study, we investigated the chemopreventive effects of dietary BS extract and its impact of gut microbiota on azoxymethane/dextran sulfate sodium (AOM/DSS)-induced colitis-associated colon cancer in mice. METHODS AND RESULTS: Male ICR mice were injected with AOM and 2% DSS via drinking water. The mice were fed with 0.25% or 0.5% BS extract, and colonic tissue were collected at 15 wk...
February 28, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28210929/effect-of-boswellia-serrata-resin-supplementation-on-basic-chemical-and-mineral-element-composition-in-the-muscles-and-liver-of-broiler-chickens
#3
A R M Al-Yasiry, B Kiczorowska, W Samolińska
Supplementation of broiler chicken diets with resin rich in bioactive components, such as different boswellic acids, could improve productivity, chemical composition, and nutritive value of produced meat. The aim of the study was to assess the effect of different levels of Boswellia serrata (BSR) supplementation in broiler chicken diet on the basic chemical composition and the Ca, P, Mg, Fe, Zn, and Cu contents in the breast and drumstick muscles and liver. The analyses involved 200 Ross 308 chickens. The broiler chickens were fed with diets containing 0 (BSR0), 1...
February 16, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28205185/use-of-an-alpha-lipoic-methylsulfonylmethane-and-bromelain-dietary-supplement-opera-%C3%A2-for-chemotherapy-induced-peripheral-neuropathy-management-a-prospective-study
#4
Isacco Desideri, Giulio Francolini, Carlotta Becherini, Francesca Terziani, Camilla Delli Paoli, Emanuela Olmetto, Mauro Loi, Marco Perna, Icro Meattini, Vieri Scotti, Daniela Greto, Pierluigi Bonomo, Susanna Sulprizio, Lorenzo Livi
Chemotherapy-induced peripheral neuropathy (CIPN) is a major clinical problem associated with a number of cytotoxic agents. OPERA(®) (GAMFARMA srl, Milan, Italy) is a new dietary supplement where α-lipoic acid, Boswellia Serrata, methylsulfonylmethane and bromelain are combined in a single capsule. The aim of this prospective study was to determine the efficacy and safety of OPERA(®) supplementation in a series of patients affected by CIPN. We selected 25 subjects with CIPN evolving during or after chemotherapy with potentially neurotoxic agents...
March 2017: Medical Oncology
https://www.readbyqxmd.com/read/28160759/five-herbs-plus-thiamine-reduce-pain-and-improve-functional-mobility-in-patients-with-pain-a-pilot-study
#5
Robert Hedaya
Context • Five herbs-Urtica dioica (stinging nettle), Boswellia serrata, Equisetum arvense, Allium sativum, and Apium graveolens-have been demonstrated to have activity at several anti-inflammatory pathways and have analgesic properties that are effective in treating chronic musculoskeletal pain. Objectives • The study intended to evaluate the clinical efficacy of a proprietary blend of U dioica, B serrata, E arvense, A sativum, A graveolens, and thiamine (vitamin B1), or "the blend," in the treatment of chronic musculoskeletal pain...
January 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28051248/movardol%C3%A2-n-acetylglucosamine-boswellia-serrata-ginger-supplementation-in-the-management-of-knee-osteoarthritis-preliminary-results-from-a-6-month-registry-study
#6
G Bolognesi, G Belcaro, B Feragalli, U Cornelli, R Cotellese, S Hu, M Dugall
OBJECTIVE: Knee Osteoarthritis (OA) is a chronic disease caused by the deterioration of cartilage in joints, which results in activation of the inflammatory response, pain, and impaired movement. Complementary therapies, particularly supplementation, in the management of moderate/severe knee OA have been gaining attention. This registry study aimed at evaluating the synergistic effect of Movardol®, a supplementation containing active ingredients with recognized anti-inflammatory activities on symptoms and levels of circulating biomarkers of knee OA...
December 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27980494/in-vivo-osteoinduction-evaluating-2-beta-coxatene-as-an-immunoinductive-compound-and-novel-ingredient-for-joint-support
#7
Katherine Spinks, James J Scaffidi
CONTEXT: Osteoarthritis (OA) is a degenerative joint disease characterized by progressive loss of articular cartilage. Many treatments lack the ability to stimulate the growth of native cartilage tissue while they simultaneously increase joint comfort. For the past few decades, dietary supplements have been investigated for the ability to both address joint inflammation and stimulate cartilage tissue. OBJECTIVES: The present study intended to examine the supplement's in vivo osteoinductive capabilities and clinical efficacy for overall joint health...
October 2016: Integrative Medicine
https://www.readbyqxmd.com/read/27966331/boswellia-serrata-gum-resin-aqueous-extract-upregulatesbdnf-but-not-creb-expression-in-adult-male-rat-hippocampus
#8
Mohammad Khalaj-Kondori, Farzaneh Sadeghi, Mohammad Ali Hosseinpourfeizi, Farzam Shaikhzadeh-Hesari, Aylar Nakhlband, Mohammad Rahmati-Yamchi
BACKGROUND/AIM: Boswellia from the family Burseraceae has been proposed for prevention of amnesia; however, the molecular mechanism by which it affects memory is not clear. To reveal the potential molecular mechanism, the effects of boswellia on the expression of two memory related genes, CREB and BDNF, were investigated. MATERIALS AND METHODS: Twenty-one male rats were randomly divided into 3 groups (n = 7): the control group received distilled water and the treatment groups received two doses of aqueous extract of Boswellia serrata gum resin (boswellia) (50 and 100 mg/kg) every day for 4 weeks...
November 17, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27879642/curcumin-and-boswellia-serrata-modulate-the-glyco-oxidative-status-and-lipo-oxidation-in-master-athletes
#9
Nino Cristiano Chilelli, Eugenio Ragazzi, Romina Valentini, Chiara Cosma, Stefania Ferraresso, Annunziata Lapolla, Giovanni Sartore
BACKGROUND: Chronic intensive exercise is associated with a greater induction of oxidative stress and with an excess of endogenous advanced glycation end-products (AGEs). Curcumin can reduce the accumulation of AGEs in vitro and in animal models. We examined whether supplementation with curcumin and Boswellia serrata (BSE) gum resin for 3 months could affect plasma levels of markers of oxidative stress, inflammation, and glycation in healthy master cyclists. METHODS: Forty-seven healthy male athletes were randomly assigned to Group 1, consisting of 22 subjects given a Mediterranean diet (MD) alone (MD group), and Group 2 consisted of 25 subjects given a MD plus curcumin and BSE (curcumin/BSE group)...
November 21, 2016: Nutrients
https://www.readbyqxmd.com/read/27822272/combined-administration-of-melissa-officinalis-and-boswellia-serrata-extracts-in-an-animal-model-of-memory
#10
Mohaddese Mahboubi, Mohsen Taghizadeh, Sayyed Alireza Talaei, Sayyed Mehdi Takht Firozeh, Ali Akbar Rashidi, Omid Reza Tamtaji
BACKGROUND: Boswellia serrata and Melissa officinalis is traditionally used for its memory enhancing effects. OBJECTIVES: In this study, we evaluated the protective effects of combined form of these extracts on memory improvement of scopolamine treated rats by the Morris water maze method. MATERIALS AND METHODS: Two groups (group 1 and 2) of animals were pretreated with combined extracts of B. serrata and M. officinalis (200, 400 mg/Kg body weight) for four weeks and then, 30 minutes before starting the experiment scopolamine was injected (0...
September 2016: Iranian Journal of Psychiatry and Behavioral Sciences
https://www.readbyqxmd.com/read/27782055/quantitative-determination-of-3-o-acetyl-11-keto-%C3%AE-boswellic-acid-akba-and-other-boswellic-acids-in-boswellia-sacra-flueck-syn-b-carteri-birdw-and-boswellia-serrata-roxb
#11
Giuseppe Mannino, Andrea Occhipinti, Massimo E Maffei
Boswellia serrata and Boswellia sacra (syn. B. carteri) are important medicinal plants widely used for their content of bioactive lipophilic triterpenes. The qualitative and quantitative determination of boswellic acids (BAs) is important for their use in dietary supplements aimed to provide a support for osteoarthritic and inflammatory diseases. We used High Performance Liquid Chromatography (HPLC)-Diode Array Detector (DAD) coupled to ElectroSpray Ionization and tandem Mass Spectrometry (ESI-MS/MS) for the qualitative and quantitative determination of BAs extracted from the gum resins of B...
October 6, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27775780/a-novel-lecithin-based-delivery-form-of-boswellic-acids-casperome%C3%A2-for-the-management-of-osteo-muscular-pain-a-registry-study-in-young-rugby-players
#12
F Franceschi, S Togni, G Belcaro, M Dugall, R Luzzi, A Ledda, L Pellegrini, R Eggenhoffner, L Giacomelli
OBJECTIVE: Several experimental studies and clinical trials support the potential of Boswellia serrata extracts (BSE) for the treatment of various inflammatory diseases. The aim of this registry study was to assess the safety and the efficacy of a novel lecithin-based delivery form of Boswellia serrata extract (Casperome®) in the supportive management of osteo-muscular pain. PATIENTS AND METHODS: 52 healthy young rugby players with acute knee pain and inflammation were recruited...
October 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27765357/a-single-dose-randomized-cross-over-two-way-open-label-study-for-comparing-the-absorption-of-boswellic-acids-and-its-lecithin-formulation
#13
Antonella Riva, Paolo Morazzoni, Christian Artaria, Pietro Allegrini, Jürgen Meins, Daniele Savio, Giovanni Appendino, Manfred Schubert-Zsilavecz, Mona Abdel-Tawab
BACKGROUND: The oral administration of the gum resin extracts of Indian frankincense (Boswellia serrata Roxb. ex Colebr) results in very low plasma concentrations of boswellic acids (BAs), being far below the pharmacologically active concentrations required in vitro for anti-inflammatory activity. For that reason the use of Indian frankincense in clinical practice and pharmaceutical development has substantially lagged behind. Recently the application of new formulation technologies resulted in a formulation of frankincense extract with lecithin, which revealed improved absorption and tissue penetration of BAs in a rodent study, leading for the first time to plasma concentrations of BAs in the range of their anti-inflammatory activity...
November 15, 2016: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/27730658/synergistic-antimicrobial-activity-of-boswellia-serrata-roxb-ex-colebr-burseraceae-essential-oil-with-various-azoles-against-pathogens-associated-with-skin-scalp-and-nail-infections
#14
S Sadhasivam, S Palanivel, S Ghosh
Antimicrobials from natural sources have gained immense importance in recent times to combat the global challenge of antibiotic resistance. Essential oils are implicated in antimicrobial action against several species. Here, we have screened nine commercially available essential oils for their antimicrobial activity against organisms associated with skin, scalp and nail infections mainly Propionibacterium acnes, Malassezia spp., Candida albicans and Trichophyton spp. Among nine essential oils, Boswellia serrata essential oil demonstrated superior antimicrobial activity against all the micro-organisms and surprisingly it showed maximum activity against Trichophyton spp...
December 2016: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/27681813/clinical-comparison-of-oral-administration-and-viscosupplementation-of-hyaluronic-acid-ha-in-early-knee-osteoarthritis
#15
M Ricci, G M Micheloni, M Berti, F Perusi, E Sambugaro, E Vecchini, B Magnan
PURPOSE: Osteoarthritis (OA) is a progressive, chronic and degenerative joint disease characterized by a loss of articular cartilage. Treatment of OA is largely palliative based on nonsteroidal anti-inflammatory drugs, opioids and injections of steroids. Regarding conservative treatment, intra-articular injections of hyaluronic acid (HA) can play a role in early symptomatic knee OA. MATERIALS AND METHODS: Between August 2015 and September 2015, sixty patients (32 males and 28 females) between 40 and 70 years old were randomly allocated into two groups: Half were treated with three weekly intra-articular injections of hyaluronic acid 1...
September 28, 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27567921/the-effects-of-alpha-boswellic-acid-on-reelin-expression-and-tau-phosphorylation-in-human-astrocytes
#16
Esmat Fathi, Fatemeh Hedayati Katouli, Gholam Hossein Riazi, Marzieh Dehghan Shasaltaneh, Elham Parandavar, Samaneh Bayati, Ali Afrasiabi, Reza Nazari
Reelin is an extracellular glycoprotein which contributes to synaptic plasticity and function of memory in the adult brain. It has been indicated that the Reelin signaling cascade participates in Alzheimer's disease (AD). Besides the neurons, glial cells such as astrocytes also express Reelin protein. While functional loss of astrocytes has been reported to be associated with AD, dysfunction of astrocytic Reelin signaling pathway has not received much attention. Therefore, we investigated the effects of α-boswellic acid (ABA) as one of the major component of Boswellia serrata resin on primary fetal human astrocytes under a stress paradigm as a possible model for AD through study on Reelin cascade...
August 27, 2016: Neuromolecular Medicine
https://www.readbyqxmd.com/read/27545217/reversal-of-the-multidrug-resistance-of-human-ileocecal-adenocarcinoma-cells-by-acetyl-11-keto-%C3%AE-boswellic-acid-via-downregulation-of-p-glycoprotein-signals
#17
Xia Xue, Fang Chen, Anxin Liu, Deqing Sun, Jing Wu, Feng Kong, Yun Luan, Xianjun Qu, Rongmei Wang
Multidrug resistance (MDR) represents a clinical obstacle to cancer chemotherapy since it causes cancer recurrence and metastasis. Acetyl-11-keto-β-boswellic acid (AKBA), an active ingredient derived from the plant Boswellia serrata, has been found to inhibit the growth of a wide variety of tumor cells, including glioma, colorectal cancer, leukemia, human melanoma, hepatocellular carcinoma, and prostate cancer cells. However, the actions of AKBA in multidrug-resistant cancer cells have not been fully elucidated...
November 15, 2016: Bioscience Trends
https://www.readbyqxmd.com/read/27516696/the-efficacy-of-boswellia-serrata-gum-resin-for-control-of-lipid-profile-and-blood-glucose-in-diabetic-patients
#18
Saeed Mehrzadi, Bahreh Tavakolifar, Hasan Fallah Huseini, Seyed Hamdollah Mosavat, Mojtaba Heydari
BACKGROUND: Regarding preclinical evidence for antidiabetic effects of Boswellia serrata, we evaluated anti-hyperglycemic and lipid-lowering effects of Boswellia serrate gum resin in type 2 diabetic patients in a double-blind randomized placebo-control trial. METHODS: Fifty-six diabetic patients were randomly allocated to two groups to receive 250 mg of the Boswellia serrate gum resin or placebo twice daily for 8 weeks, in addition to their routine antidiabetic treatments...
May 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27515127/aqueous-and-ethanolic-extracts-of-boswellia-serrata-protect-against-focal-cerebral-ischemia-and-reperfusion-injury-in-rats
#19
Fatemeh Forouzanfar, Hossein Hosseinzadeh, Alireza Ebrahimzadeh Bideskan, Hamid R Sadeghnia
Oxidative stress and cell apoptosis play major roles in neuronal injury after ischemia-reperfusion (I-R) injury. Boswellia serrata is a medicinal plant with antioxidant properties. Acetyl-11-keto-β-boswellic acid (AKBA) is an active triterpenoid compound from B. serrate. In the current study, the neuroprotective effects of aqueous and ethanolic extracts of B. serrata (named ABS and EBS, respectively) and AKBA were investigated against middle cerebral artery occlusion-induced cerebral I-R injury in rats...
December 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/27494534/boswellia-serrata-protects-against-glutamate-induced-oxidative-stress-and-apoptosis-in-pc12-and-n2a-cells
#20
Arezoo Rajabian, Mohammad Taher Boroushaki, Parichehr Hayatdavoudi, Hamid Reza Sadeghnia
This study was designed to investigate whether the extract from Boswellia serrata oleo-gum resin (BSE) can protect against glutamate-induced oxidative damage and cytotoxicity in PC12 and N2a cell lines. Using a simple and reliable reverse-phase high-performance liquid chromatography (HPLC), the amount of 3-acetyl-11-keto-β-boswellic acid (AKBA) in the BSE was found to be 18.5% w/w. The results confirmed that BSE and AKBA, at concentrations as high as 100 μg/mL or 10 μM, respectively, caused no significant cytotoxicity or apoptotic cell death...
November 2016: DNA and Cell Biology
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