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Crataegus-pinnatifida

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https://www.readbyqxmd.com/read/28757888/rhodiolae-kirliowii-radix-et-rhizoma-and-crataegus-pinnatifida-fructus-extracts-effectively-inhibit-bk-virus-and-jc-virus-infection-of-host-cells
#1
San-Yuan Chen, Ru-Hsiou Teng, Meilin Wang, Pei-Lain Chen, Mien-Chun Lin, Cheng-Huang Shen, Chun-Nun Chao, Ming-Ko Chiang, Chiung-Yao Fang, Deching Chang
The human polyomaviruses BK (BKPyV) and JC (JCPyV) are ubiquitous pathogens long associated with severe disease in immunocompromised individuals. BKPyV causes polyomavirus-associated nephropathy and hemorrhagic cystitis, whereas JCPyV is the causative agent of the fatal demyelinating disease progressive multifocal leukoencephalopathy. No effective therapies targeting these viruses are currently available. The goal of this study was to identify Chinese medicinal herbs with antiviral activity against BKPyV and JCPyV...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28710433/high-density-genetic-linkage-map-construction-and-quantitative-trait-locus-mapping-for-hawthorn-crataegus-pinnatifida-bunge
#2
Yuhui Zhao, Kai Su, Gang Wang, Liping Zhang, Jijun Zhang, Junpeng Li, Yinshan Guo
Genetic linkage maps are an important tool in genetic and genomic research. In this study, two hawthorn cultivars, Qiujinxing and Damianqiu, and 107 progenies from a cross between them were used for constructing a high-density genetic linkage map using the 2b-restriction site-associated DNA (2b-RAD) sequencing method, as well as for mapping quantitative trait loci (QTL) for flavonoid content. In total, 206,411,693 single-end reads were obtained, with an average sequencing depth of 57× in the parents and 23× in the progeny...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28601279/escitalopram-or-novel-herbal-treatments-differentially-alter-cytokine-and-behavioral-responses-to-immune-challenge
#3
Ronit Avitsur, Shalva Paley, Motty Franko, Nizan Wolff, Nir Eyal, Ravid Doron
Studies suggest that inflammation is involved in the pathophysiology of depression. The present study examined the effects of the commonly used antidepressant escitalopram, in comparison with a novel herbal treatment (NHT) consisted of Crataegus pinnatifida, Triticum aestivum, Lilium brownii and Fructus Ziziphus jujuba, on cytokine and behavioral responses to an immune challenge. Escitalopram augmented lipopolysaccharide-induced tumor necrosis factor (TNF)-α peripheral secretion and induced a faster kinetics of interleukin-1β secretion, while marginally reducing sickness behavior...
August 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28539730/near-infrared-spectroscopy-as-a-process-analytical-technology-tool-for-monitoring-the-parching-process-of-traditional-chinese-medicine-based-on-two-kinds-of-chemical-indicators
#4
Kaiyue Li, Weiying Wang, Yanping Liu, Su Jiang, Guo Huang, Liming Ye
BACKGROUND: The active ingredients and thus pharmacological efficacy of traditional Chinese medicine (TCM) at different degrees of parching process vary greatly. OBJECTIVE: Near-infrared spectroscopy (NIR) was used to develop a new method for rapid online analysis of TCM parching process, using two kinds of chemical indicators (5-(hydroxymethyl) furfural [5-HMF] content and 420 nm absorbance) as reference values which were obviously observed and changed in most TCM parching process...
April 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28486427/an-efficient-method-for-the-preparative-isolation-and-purification-of-flavonoids-from-leaves-of-crataegus-pinnatifida-by-hsccc-and-pre-hplc
#5
Lei Wen, Yunliang Lin, Ruimin Lv, Huijiao Yan, Jinqian Yu, Hengqiang Zhao, Xiao Wang, Daijie Wang
In this work, flavonoid fraction from the leaves of Crataegus pinnatifida was separated into its seven main constituents using a combination of HSCCC coupled with pre-HPLC. In the first step, the total flavonoid extract was subjected to HSCCC with a two-solvent system of chloroform/methanol/water/n-butanol (4:3:2:1.5, v/v), yielding four pure compounds, namely (-)-epicatechin (1), quercetin-3-O-(2,6-di-α-l-rhamnopyranosyl)-β-d-galactopyranoside (2), 4''-O-glucosylvitexin (3) and 2''-O-rhamnosylvitexin (4) as well as a mixture of three further flavonoids...
May 9, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28165392/sphingosine-kinase-1-involves-the-inhibitory-action-of-hif-1%C3%AE-by-chlorogenic-acid-in-hypoxic-du145-cells
#6
Myoung-Sun Lee, Seon-Ok Lee, Kyu-Ri Kim, Hyo-Jeong Lee
Hypoxia enhances cancer development in a solid tumor. Hypoxia-inducible factor-1 α (HIF-1α) is a transcription factor that is dominantly expressed under hypoxia in solid tumor cells and is a key factor that regulates tumor. HIF-1α regulates several target genes involved in many aspects of cancer progression, including angiogenesis, metastasis, anti-apoptosis and cell proliferation as well as imparts resistance to cancer treatment. In this study, we assessed Crataegus Pinnatifida Bunge var. typical Schneider ethanol extract (CPE) for its anti-cancer effects in hypoxia-induced DU145 human prostate cancer cell line...
February 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28123324/antiaging-effects-of-the-mixture-of-panax-ginseng-and-crataegus-pinnatifida-in-human-dermal-fibroblasts-and-healthy-human-skin
#7
Eunson Hwang, Sang-Yong Park, Chang Shik Yin, Hee-Taek Kim, Yong Min Kim, Tae Hoo Yi
BACKGROUND: Human skin undergoes distinct changes throughout the aging process, based on both intrinsic and extrinsic factors. In a process called photoaging, UVB irradiation leads to upregulation of matrix metalloproteinase-1, which then causes collagen degradation and premature aging. Mixtures of medicinal plants have traditionally been used as drugs in oriental medicine. Based on the previously reported antioxidant properties of Panax ginseng Meyer and Crataegus pinnatifida, we hypothesized that the mixture of P...
January 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28119096/hawthorn-crataegus-pinnatifida-bunge-leave-flavonoids-attenuate-atherosclerosis-development-in-apoe-knock-out-mice
#8
Pengzhi Dong, Lanlan Pan, Xiting Zhang, Wenwen Zhang, Xue Wang, Meixiu Jiang, Yuanli Chen, Yajun Duan, Honghua Wu, Yantong Xu, Peng Zhang, Yan Zhu
ETHNOPHARMACOLOGICAL RELEVANCE: Hawthorn (Crataegus pinnatifida Bunge) leave have been used to treat cardiovascular diseases in China and Europe. Hawthorn leave flavonoids (HLF) are the main part of extraction. Whether hawthorn leave flavonoids could attenuate the development of atherosclerosis and the possible mechanism remain unknown. MATERIALS AND METHODS: High-fat diet (HFD) mixed with HLF at concentrations of 5mg/kg and 20mg/kg were administered to apolipoprotein E (apoE) knock out mice...
February 23, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28025124/major-triterpenoids-in-chinese-hawthorn-crataegus-pinnatifida-and-their-effects-on-cell-proliferation-and-apoptosis-induction-in-mda-mb-231-cancer-cells
#9
Lingrong Wen, Ruixue Guo, Lijun You, Arshad Mehmood Abbasi, Tong Li, Xiong Fu, Rui Hai Liu
The cytotoxicity and antiproliferative effect of phytochemicals presenting in the fruits of Chinese hawthorn (Crataegus pinnatifida) were evaluated. Shanlihong (Crataegus pinnatifida Bge. var. major N.E.Br.) variety possessed significant levels of flavonoids and triterpenoids, and showed potent antiproliferative effect against HepG2, MCF-7 and MDA-MB- 231 human cancer cells lines. Triterpenoids-enriched fraction (S9) prepared by Semi-preparative HPLC, and its predominant ingredient ursolic acid (UA) demonstrated remarkably antiproliferative activities for all the tested cancer cell lines...
February 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/27807684/inhibition-of-murine-norovirus-and-feline-calicivirus-by-edible-herbal-extracts
#10
Dong Joo Seo, Changsun Choi
Human noroviruses (HuNoVs) cause foodborne and waterborne viral gastroenteritis worldwide. Because HuNoV culture systems have not been developed thus far, no available medicines or vaccines preventing infection with HuNoVs exist. Some herbal extracts were considered as phytomedicines because of their bioactive components. In this study, the inhibitory effects of 29 edible herbal extracts against the norovirus surrogates murine norovirus (MNV) and feline calicivirus (FCV) were examined. FCV was significantly inhibited to 86...
March 2017: Food and Environmental Virology
https://www.readbyqxmd.com/read/27792149/herbal-formula-ht048-attenuates-diet-induced-obesity-by-improving-hepatic-lipid-metabolism-and-insulin-resistance-in-obese-rats
#11
Yoon Hee Lee, Bora Jin, Sung Hyun Lee, MiKyung Song, HyeonHui Bae, Byung Jae Min, Juyeon Park, Donghun Lee, Hocheol Kim
It is well established that obesity causes a variety of chronic diseases such as cardiovascular diseases and diabetes. Despite the diligent scientific efforts to find effective ways to lower the level of obesity, the size of obese population grows continuously around the world. Here we present the results that show feeding diet containing HT048, a mixture of the extracts of Crataegus pinnatifida leaves and Citrus unshiu peel, two of the well-known traditional herbal medicines in Eastern Asia, decreases obesity in rats...
October 25, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27754461/in-vitro-study-on-anti-hepatitis-c-virus-activity-of-spatholobus-suberectus-dunn
#12
Shao-Ru Chen, An-Qi Wang, Li-Gen Lin, Hong-Cong Qiu, Yi-Tao Wang, Ying Wang
Hepatitis C virus (HCV) infects 200 million people worldwide, and 75% of HCV cases progress into chronic infections, which consequently cause cirrhosis and hepatocellular carcinoma. HCV infection is treated with currently considered standard drugs, including direct anti-viral agents (DAAs), alone or in combination with peginterferon-α plus ribavirin. However, sustained viral responses vary in different cohorts, and high costs limit the broad use of DAAs. In this study, the ethanol and water extracts of 12 herbs from Lingnan in China were examined in terms of their inhibitory effect on HCV replication...
October 15, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27706748/classification-and-phylogenetic-analysis-of-chinese-hawthorn-assessed-by-plant-and-pollen-morphology
#13
S L Y Ma, Y M Lu
The Chinese hawthorn (Crataegus pinnatifida Bge. var. major N.E.Br.) is uniquely originated in northern China. The ecological and horticultural importance of Chinese hawthorn is considerable and some varieties are valued for their fruit or medicine extracts. Its taxonomy and phylogeny remain poorly understood. Apart from general plant morphological traits, pollen is an important trait for the classification of plants and their evolutionary origin. However, few studies have investigated the pollen of Chinese hawthorn...
September 19, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27519059/genome-sequences-of-three-apple-chlorotic-leaf-spot-virus-isolates-from-hawthorns-in-china
#14
Wei Guo, Wenyan Zheng, Mei Wang, Xiaohong Li, Yue Ma, Hongyan Dai
The genome sequences of Apple chlorotic leaf spot virus (ACLSV) isolates from three accessions of hawthorns (Crataegus pinnatifida) grown at Shenyang Agricultural University were determined using Illumina RNA-seq. To confirm the assembly data from the de novo sequencing, two ACLSV genomic sequences (SY01 and SY02) were sequenced using the Sanger method. The SY01 and SY02 sequences obtained with the Sanger method showed 99.5% and 99.7% nucleotide identity with the transcriptome data, respectively. The genome sequences of the hawthorn isolates SY01, SY02 and SY03 (GenBank accession nos...
2016: PloS One
https://www.readbyqxmd.com/read/27374510/effects-of-pretreatments-on-anthocyanin-composition-phenolics-contents-and-antioxidant-capacities-during-fermentation-of-hawthorn-crataegus-pinnatifida-drink
#15
Suwen Liu, Xuedong Chang, Xiufeng Liu, Zhanwei Shen
The effect of microwave and heat pretreatment on the content and composition of anthocyanins, phenolics, and the antioxidant capacity of hawthorn drink were studied. Nine anthocyanins were isolated by chromatographic separation from the Zirou hawthorn source and their structure identified using HPLC-DAD-ESI/MS analysis. Heat and microwave pretreatments had a significant impact on the relative contents of hawthorn anthocyanins, such as cyanidin-3-galactoside (82.9% and 76.9%, respectively) and cyanidin-3-glucoside (9...
December 1, 2016: Food Chemistry
https://www.readbyqxmd.com/read/27187458/hawthorn-fruit-extract-elevates-expression-of-nrf2-ho-1-and-improves-lipid-profiles-in-ovariectomized-rats
#16
Jeong-Hyun Yoo, Yanan Liu, Hyun-Sook Kim
The purpose of this study was to investigate the effects of hawthorn (Crataegus pinnatifida Bunge) extract on the lipid profiles and antioxidant properties in ovariectomized (OVX) rats. After ovariectomy, the rats were randomly divided into four groups: the non-OVX control (Sham), the OVX-control (OVX), the OVX + 100 mg/kg b.w. of hawthorn extract (OL), and the OVX + 200 mg/kg b.w. of hawthorn extract (OH). The final body weights of the OVX group were significantly increased, but the increment was significantly decreased in hawthorn groups (p < 0...
May 13, 2016: Nutrients
https://www.readbyqxmd.com/read/27074499/antioxidant-properties-of-phenolic-compounds-in-renewable-parts-of-crataegus-pinnatifida-inferred-from-seasonal-variations
#17
Meng Luo, Xuan Yang, Jiao-Yang Hu, Jiao Jiao, Fan-Song Mu, Zhuo-Yue Song, Qing-Yan Gai, Qi Qiao, Xin Ruan, Yu-Jie Fu
In this study, the effect of seasonal variations on Crataegus pinnatifida, changes in antioxidant activity and active components in C. pinnatifida leaves, roots, twigs, and fruits from May to October were investigated. Through correlation analysis of climatic factors and 7 phenolic compounds yield, the phenolic compounds content was positively correlated with temperatures and daytime. The correlation coefficient of temperatures and daytime were 0.912 and 0.829, respectively. 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, 2,2'-azino-bis 3-ethylbenzothiazoline-6-sulphonic acid (ABTS) radical scavenging and reducing power tests were employed to evaluate the antioxidant activity of the C...
May 2016: Journal of Food Science
https://www.readbyqxmd.com/read/27019563/comparation-of-hypolipidemic-and-antioxidant-effects-of-aqueous-and-ethanol-extracts-of-crataegus-pinnatifida-fruit-in-high-fat-emulsion-induced-hyperlipidemia-rats
#18
Feng Shao, Lifei Gu, Huijuan Chen, Ronghua Liu, Huilian Huang, Gang Ren
BACKGROUND: Hawthorn (Crataegus pinnatifida) is a Chinese medicinal plant traditionally used in the treatment of hyperlipidemia. Recently, studies indicated free radical scavenging was one of the major pathways to alleviate hyperlipidemia. Moreover, hawthorn fruit is a rich source of phenols, which quench free radical and attenuate hyperlipidemia. However, the phenols vary with processing methods, especially solvent type. OBJECTIVE: Our aim was to compare hypolipidemic and antioxidant effects of aqueous and ethanol extracts of hawthorn fruit in hyperlipidemia rats...
January 2016: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/27005663/antioxidant-capacities-of-hot-water-extracts-and-endopolysaccharides-of-selected-chinese-medicinal-fruits
#19
Sang Chul Jeong, Ratna Tulasi, Sundar Rao Koyyalamudi
Fruits are a rich source of antioxidants and traditional Chinese fruits have been studied for their chemopreventive and chemotherapeutic properties against cancers and other diseases. The total phenol and flavonoid contents of eleven Chinese fruits extracts were determined. Total phenolic and flavonoid contents were estimated by both the Folin-Ciocalteau and aluminium chloride methods. The antioxidant activities were evaluated by four assays: a biological assay using Saccharomyces cerevisiae, DPPH radical scavenging activity, chelating ability for ferrous ions and ferric reducing antioxidant power (FRAP)...
2016: Cancers
https://www.readbyqxmd.com/read/26807707/application-of-alkyl-polyglycoside-surfactant-in-ultrasonic-assisted-extraction-followed-by-macroporous-resin-enrichment-for-the-separation-of-vitexin-2%C3%A2-o-rhamnoside-and-vitexin-from-crataegus-pinnatifida-leaves
#20
Feng Han, Yupin Guo, Huiyan Gu, Fenglan Li, Baozhong Hu, Lei Yang
An alkyl polyglycoside (APG) surfactant was used in ultrasonic-assisted extraction to effectively extract vitexin-2″-O-rhamnoside (VOR) and vitexin (VIT) from Crataegus pinnatifida leaves. APG0810 was selected as the surfactant. The extraction process was optimized for ultrasonic power, the APG concentration, ultrasonic time, soaking time, and liquid-solid ratio. The proposed approach showed good recovery (99.80-102.50% for VOR and 98.83-103.19% for VIT) and reproducibility (relative standard deviation, n=5; 3...
February 15, 2016: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
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