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https://www.readbyqxmd.com/read/27933619/monocyte-mediated-activation-of-endothelial-cells-occurs-only-after-binding-to-extracellular-vesicles-from-red-blood-cell-products-a-process-mediated-by-%C3%AE-integrin
#1
Marleen Straat, Maike E van Hezel, Anita Böing, Anita Tuip-De Boer, Nina Weber, Rienk Nieuwland, Robin van Bruggen, Nicole P Juffermans
BACKGROUND: Red blood cell (RBC) transfusion is associated with organ failure. The mechanism remains unknown, but may include adherence of blood cells to the microvasculature. We hypothesized that RBC-derived extracellular vesicles (EVs) interact with monocytes to activate endothelial cells. STUDY DESIGN AND METHODS: Human umbilical vein endothelial cells were incubated with supernatant from fresh and stored RBC units either containing EVs or depleted from EVs, with or without the addition of immune cells...
December 2016: Transfusion
https://www.readbyqxmd.com/read/27933440/modern-role-of-clinical-ultrasound-in-liver-abscess-and-echinococcosis
#2
REVIEW
Rita Barosa, João Pinto, Ana Caldeira, Eduardo Pereira
In the Western world, liver abscesses are predominantly of pyogenic origin and can present a wide range of ultrasonographic features, from a solid mass to a cystic cavity. Amoebic abscesses are endemic in tropical areas and typically round single lesions. Echinococcal cyst is diagnosed by ultrasound (US). Serology is particularly useful when pathognomonic US features are absent. Treatment is determined based on the WHO ultrasonographic classification, and puncture, aspiration, injection, re-aspiration (PAIR) is a US-guided therapeutic option...
December 8, 2016: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/27933413/investigation-on-genetic-thrombophilic-factors-in-ffpe-autopsy-tissue-from-subjects-who-died-from-pulmonary-embolism
#3
Francesco Brandimarti, Federica Alessandrini, Mauro Pesaresi, Chiara Catalani, Letizia De Angelis, Roberta Galeazzi, Simona Giovagnetti, Rosaria Gesuita, Elisa Righi, Raffaele Giorgetti, Adriano Tagliabracci
Venous thromboembolism (VTE) is a multifactorial disease determined by a combination of inherited and acquired factors. Inherited factors include mutations in the genes coding for coagulation factors, some of which seem to exert a differential influence on the risk of developing deep vein thrombosis (DVT) and pulmonary embolism (PE). In post-mortem studies of subjects who have died from pulmonary embolism (PE), the analysis of the factors that may have augmented the VTE risk is often limited to acquired factors...
December 9, 2016: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/27933378/a-train-track-technique-in-anatomic-reconstruction-of-svc-bifurcation-complicated-by-cardiac-tamponade-an-introspection
#4
Karunakaravel Karuppasamy, Mohammed Al-Natour, Ram Kishore Gurajala
This report describes a stenting technique used to anatomically reconstruct superior vena cava (SVC) bifurcation in a patient with benign SVC syndrome. After recanalizing the SVC bifurcation, we exchanged two 0.035-in. wires for two 0.018-in. wires, deployed the SVC stent over these two wires ("train-track" technique), and stented each innominate vein over one wire. However, our decisions to recanalize both innominate veins, use the "buddy-wire" technique for SVC dilation, and dilate the SVC to 16 mm before stent deployment likely contributed to SVC tear, which was managed by resuscitation, SVC stent placement, and pericardial drainage...
December 8, 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27933375/a-novel-method-of-adrenal-venous-sampling-via-an-antecubital-approach
#5
Xiongjing Jiang, Hui Dong, Meng Peng, Wuqiang Che, Yubao Zou, Lei Song, Huimin Zhang, Haiying Wu
PURPOSE: Currently, almost all adrenal venous sampling (AVS) procedures are performed by femoral vein access. The purpose of this study was to establish the technique of AVS via an antecubital approach and evaluate its safety and feasibility. MATERIALS AND METHODS: From January 2012 to June 2015, 194 consecutive patients diagnosed as primary aldosteronism underwent AVS via an antecubital approach without ACTH simulation. Catheters used for bilateral adrenal cannulations were recorded...
December 8, 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27932866/effect-of-peritoneal-dialysis-fluid-containing-osmo-metabolic-agents-on-human-endothelial-cells
#6
Mario Bonomini, Sara Di Silvestre, Pamela Di Tomo, Natalia Di Pietro, Domitilla Mandatori, Lorenzo Di Liberato, Vittorio Sirolli, Francesco Chiarelli, Cesare Indiveri, Assunta Pandolfi, Arduino Arduini
BACKGROUND: The use of glucose as the only osmotic agent in peritoneal dialysis (PD) solutions (PDSs) is believed to exert local (peritoneal) and systemic detrimental actions, particularly in diabetic PD patients. To improve peritoneal biocompatibility, we have developed more biocompatible PDSs containing xylitol and carnitine along with significantly less amounts of glucose and have tested them in cultured Human Vein Endothelial Cells (HUVECs) obtained from the umbilical cords of healthy (C) and gestational diabetic (GD) mothers...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27932624/allele-rs2010963-c-of-the-vegfa-gene-is-associated-with-the-decreased-risk-of-primary-varicose-veins-in-ethnic-russians
#7
Alexandra S Shadrina, Mariya A Smetanina, Ekaterina A Sokolova, Darya V Shamovskaya, Kseniya S Sevost'ianova, Andrey I Shevela, Evgenii Y Soldatsky, Evgenii I Seliverstov, Marina Y Demekhova, Oleg A Shonov, Evgeny A Ilyukhin, Elena N Voronina, Ilya V Pikalov, Igor A Zolotukhin, Alexander I Kirienko, Maxim L Filipenko
OBJECTIVE: To study the association of polymorphisms rs699947, rs2010963, rs3025039 in the VEGFA gene region and rs1870377, rs2305949, rs2071559 in the VEGFR2 gene region with the risk of primary varicose veins in ethnic Russians. METHODS: Genotypes were determined by real-time PCR allelic discrimination. The case group consisted of 448 patients with primary varicose veins and the control group comprised 609 individuals without a history of chronic venous disease...
December 8, 2016: Phlebology
https://www.readbyqxmd.com/read/27932510/embolization-of-intracranial-dural-arteriovenous-fistulas-using-phil-liquid-embolic-agent-in-26-patients-a-multicenter-study
#8
S Lamin, H S Chew, S Chavda, A Thomas, M Piano, L Quilici, G Pero, M Holtmannspolter, M E Cronqvist, A Casasco, L Guimaraens, L Paul, A Gil Garcia, A Aleu, R Chapot
BACKGROUND AND PURPOSE: The introduction of liquid embolic agents has revolutionized endovascular approach to cranial vascular malformations. The aim of the study was to retrospectively assess the efficacy and safety of Precipitating Hydrophobic Injectable Liquid (PHIL), a new nonadhesive liquid embolic agent, in the treatment of patients with cranial dural arteriovenous fistulas. The primary end point was the rate of complete occlusion of dural arteriovenous fistulas. Secondary end points included the incidence of adverse events and clinical status at 3-month follow-up...
December 8, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27932509/use-of-phase-contrast-mra-to-assess-intracranial-venous-sinus-resistance-to-drainage-in-healthy-individuals
#9
S Fall, G Pagé, J Bettoni, R Bouzerar, O Balédent
BACKGROUND AND PURPOSE: Resistance to blood flow in the cerebral drainage system may affect cerebral hemodynamics. The objective of the present study was to use phase-contrast MRA to quantify resistance to drainage of blood across branches of the venous sinus tree and to determine whether the resistance to drainage values correlated with internal jugular vein outflows. MATERIALS AND METHODS: We performed whole-head phase-contrast MRA and 2D phase-contrast MR imaging in 31 healthy volunteers...
December 8, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27932306/analysis-of-the-outcomes-in-central-venous-access-port-implantation-performed-by-residents-via-the-internal-jugular-vein-and-subclavian-vein
#10
Hajime Matsushima, Tomohiko Adachi, Toru Iwata, Takashi Hamada, Hiroki Moriuchi, Manpei Yamashita, Tomoo Kitajima, Hitoshi Okubo, Susumu Eguchi
OBJECTIVE: The central venous access port (CVAP) has played an important role in the safe administration of chemotherapy and parenteral nutrition. The aim of the present study was to clarify the optimal access vein for CVAP implantation when performed by residents rather than attending surgeons. METHODS: A consecutive cases of CVAP implantation via the subclavian vein (SV) using a landmark-guided technique or via the internal jugular vein (JV) using an ultrasound-guided technique were divided into 2 groups according to whether the intervention was performed by a resident or an attending surgeon...
December 5, 2016: Journal of Surgical Education
https://www.readbyqxmd.com/read/27932281/nutcracker-syndrome-a-rare-cause-of-left-flank-pain-that-can-also-manifest-as-unexplained-pelvic-pain
#11
Jean-Marie Berthelot, Frédéric Douane, Yves Maugars, Eric Frampas
Nutcracker syndrome (NCS) is symptomatic unilateral renal venous hypertension due to compression of the left renal vein between the superior mesenteric artery and aorta (anterior NCS) or between the aorta and spine (posterior NCS). The left ovarian or spermatic vein empties into the left renal vein and is an additional site of venostasis in about half the cases of NCS. The presenting symptom of NCS in about half the cases is atypical left flank pain suggesting a disorder of the lower ribs or thoracolumbar spinal junction, particularly as the pain worsens with standing and increased lumbar lordosis...
December 5, 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/27932185/inferior-vena-cava-duodenal-drainage-in-pancreas-alone-transplantation-for-chronic-pancreatitis-a-case-report
#12
B H Choi, Y M Park, K H Yang, C W Chu, J H Ryu
Enteric drainage has been the main trend in solitary pancreas transplantation. Compared with bladder drainage, it does not cause metabolic or urologic complications, but there is no way to perform immunologic monitoring, except by graft pancreas biopsy. Additionally, although portal drainage of the graft vein is considered physiological drainage, it has more of a risk for surgical complications. To overcome these disadvantages, we successfully performed inferior vena cava (IVC)-duodenal drainage in pancreas alone transplantation...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27932178/extra-anatomical-meso-portal-venous-jump-graft-repair-for-early-portal-vein-thrombosis-after-liver-transplant-in-an-infant-with-a-hypoplastic-portal-vein-a-case-report
#13
R Matsumoto, K Uchida, S Nishida, E R Island, D M Levi, J Fan, A Tekin, G Selvaggi, A G Tzakis
BACKGROUND AND PURPOSE: Small infants with biliary atresia and hypoplastic portal veins (PV) are at risk for portal vein thrombosis (PVT) after liver transplantation (LT), which can lead to graft loss and mortality. Extra-anatomical PV reconstruction techniques have been established for adult cases of PVT; however, they have not been widely accepted for infants. METHODS: Here, we report the successful use of an extra-anatomical meso-portal venous jump graft to treat early PVT after LT in a 6-month-old infant with biliary atresia and PV hypoplasia...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27932173/a-case-report-of-severe-hepatic-artery-vasospasm-induced-by-hepatic-arterial-buffer-response-after-liver-transplantation
#14
Y Hiraki, K Uchida, S Nishida, D M Levi, G Selvaggi, A Tekin, J Fan, T Froud, A G Tzakis
The management of severe hepatic artery vasospasm soon after liver transplantation (LT) is challenging because it can lead to hepatic artery thrombosis and subsequent graft failure. A 61-year-old man with hepatitis C cirrhosis and portal vein thrombosis received a deceased donor LT. On postoperative day 1, Doppler ultrasonography revealed a high-resistance waveform in the hepatic artery. Angiography showed severe vasospasm of the donor hepatic artery on postoperative day 3. Strong hepatic arterial buffer response (HABR) was considered for this etiology due to high portal vein velocity...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27932170/living-donor-liver-transplantation-in-a-patient-with-extensive-portomesenteric-venous-thrombosis-case-report
#15
S Choi, K K Kim, W S Lee, J M Kang, Y H Park
Extensive portomesenteric venous thrombus preventing restoration of adequate portal venous flow used to be considered a contraindication to liver transplantation. The subject was a 49-year-old male with hepatitis B cirrhosis and extensive thrombosis of portal, splenic, and superior mesenteric veins, and two large collateral vessels; one dilated and tortuous inferior to the pancreaticoduodenal vein and relevant to splanchnic venous return and the other a dilated coronary vein relevant to splenic venous return...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27932155/late-allograft-renal-vein-thrombosis-treated-with-anticoagulation-alone-a-case-report
#16
C Ferreira, L Pereira, P Pereira, I Tavares, S Sampaio, M Bustorff, M Pestana
BACKGROUND: Allograft renal vein thrombosis is a rare complication of kidney transplantation. Most cases occur in the first 2 weeks after transplantation, but there are cases described many years after the transplant surgery. Allograft loss is the usual outcome. METHODS: We present a case of a renal transplant recipient with allograft renal vein thrombosis associated with deep venous thrombosis of a lower limb, 9 years after transplantation. He was successfully treated with anticoagulation alone, with recovery of allograft function...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27932149/portal-vein-inflow-from-enlarged-coronary-vein-in-liver-transplantation-surgical-approach-and-technical-tips-a-case-report
#17
M Safwan, S Nagai, M S Abouljoud
Portal vein thrombosis is common in patients with end-stage liver disease, with an incidence as high as 26% in liver transplant candidates. It is known to be associated with a high risk of morbidity and mortality posttransplantation, and its management can be challenging. The management options range from a simple thrombendvenectomy to multivisceral transplantation in cases with diffuse portomesenteric thrombosis. We report a case of liver transplantation in which we performed a rare reconstruction of the portal vein...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27932135/influence-of-body-mass-index-on-venous-thrombotic-complications-of-liver-transplants
#18
A R Molina, A R Vílchez, M B Domínguez, A N García, C M San Miguel, A R R González, Y S Fundora
OBJECTIVE: To analyze venous thrombotic complications in transplanted patients as a function of their body mass index (BMI). MATERIALS AND METHODS: This single-center, observational retrospective study of individuals undergoing liver transplantation between January 2008 and December 2014 analyzed the frequency of pretransplant portal thrombosis, post-transplant venous complications (early and late portal thrombosis), deep vein thrombosis, pulmonary thromboembolism and the survival outcomes as a function of World Health Organization BMI class...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27931947/transection-of-the-omohyoid-muscle-as-an-aid-during-vagal-nerve-stimulator-implantation
#19
June Yowtak, Patrick Jenkins, Cole Giller
BACKGROUND: Exposure of the carotid sheath during VNS implantation is usually straightforward, but can be difficult for patients with a large body habitus. In addition, the exposure must be done with care if the surgeon wishes to keep the vagus nerve in situ without using retractors that might impair access. OBJECTIVE: To describe the use of the omohyoid muscle as a landmark for the jugular vein, and to report how transection of the omohyoid can facilitate a rapid and wide exposure of the carotid sheath...
December 5, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27931945/dural-arteriovenous-fistula-of-the-sinus-of-the-lesser-sphenoid-wing-presenting-with-pontine-hemorrhage-case-report
#20
Hideki Nakajima, Tomoya Ishiguro, Aiko Terada, Masaki Komiyama
BACKGROUND: Dural arteriovenous fistulas (DAVFs) of the sinus of the lesser sphenoid wing (SLSW) with leptomeningeal drainage are rare. We report a patient with a DAVF of the SLSW draining into the basal vein of Rosenthal (BVR) presenting with pontine hemorrhage. CASA DESCRIPTION: A 71-year-old man presented with sudden right hemisensory disturbance of the arm and leg. Brain computed tomography showed left pontine hemorrhage and cerebral angiography revealed a DAVF of the left SLSW...
December 5, 2016: World Neurosurgery
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