keyword
https://read.qxmd.com/read/38537086/effect-of-dexmedetomidine-on-the-incidence-of-postoperative-acute-kidney-injury-in-living-donor-liver-transplantation-recipients-a-randomized-controlled-trial
#1
JOURNAL ARTICLE
Hye-Mee Kwon, Sa-Jin Kang, Sang-Bin Han, Jae Hwan Kim, Sung-Hoon Kim, In-Gu Jun, Jun-Gol Song, Gyu-Sam Hwang
BACKGROUND: Acute kidney injury (AKI) is one of the most common complications after living-donor liver transplantation (LDLT) that has great impact on recipient and graft outcomes. Dexmedetomidine is reported to decrease the incidence of AKI. In the current study, we investigated whether intraoperative dexmedetomidine infusion would reduce the AKI following LDLT. MATERIAL AND METHODS: In total, 205 adult patients undergoing elective LDLT were randomly assigned to the dexmedetomidine group (n=103) or the control group (n=102)...
April 3, 2024: International Journal of Surgery
https://read.qxmd.com/read/38536802/predicting-successful-weaning-from-mechanical-ventilation-by-reduction-in-positive-end-expiratory-pressure-level-using-machine-learning
#2
JOURNAL ARTICLE
Seyedmostafa Sheikhalishahi, Mathias Kaspar, Sarra Zaghdoudi, Julia Sander, Philipp Simon, Benjamin P Geisler, Dorothea Lange, Ludwig Christian Hinske
Weaning patients from mechanical ventilation (MV) is a critical and resource intensive process in the Intensive Care Unit (ICU) that impacts patient outcomes and healthcare expenses. Weaning methods vary widely among providers. Prolonged MV is associated with adverse events and higher healthcare expenses. Predicting weaning readiness is a non-trivial process in which the positive end-expiratory pressure (PEEP), a crucial component of MV, has potential to be indicative but has not yet been used as the target...
March 2024: PLOS Digit Health
https://read.qxmd.com/read/38536630/influenza-associated-outcomes-and-healthcare-utilization-by-race-and-ethnicity-in-the-usa-a-retrospective-cohort-study-using-the-national-inpatient-sample-database
#3
JOURNAL ARTICLE
Mohamad El Labban, Wigdan Farah, Perla Mansour, Karine Eid, Yewande E Odeyemi
BACKGROUND: The influenza virus continues to be a public health concern every season. We aimed to evaluate influenza-associated outcomes and healthcare utilization by race and ethnicity. METHODS: We conducted a retrospective cohort study using the National Inpatient Sample across 2019 and 2020. Influenza pneumonia was selected as the principal diagnosis. Outcomes included mortality, use of respiratory support ventilation, length of stay, and total hospitalization charge...
March 27, 2024: Journal of Racial and Ethnic Health Disparities
https://read.qxmd.com/read/38536629/association-of-premorbid-glp-1ra-and-sglt-2i-prescription-alone-and-in-combination-with-covid-19-severity
#4
JOURNAL ARTICLE
Klara R Klein, Trine J Abrahamsen, Anna R Kahkoska, G Caleb Alexander, Christopher G Chute, Melissa Haendel, Stephanie S Hong, Hemalkumar Mehta, Richard Moffitt, Til Stürmer, Kajsa Kvist, John B Buse
INTRODUCTION: People with type 2 diabetes are at heightened risk for severe outcomes related to COVID-19 infection, including hospitalization, intensive care unit admission, and mortality. This study was designed to examine the impact of premorbid use of glucagon-like peptide-1 receptor agonist (GLP-1RA) monotherapy, sodium-glucose cotransporter-2 inhibitor (SGLT-2i) monotherapy, and concomitant GLP1-RA/SGLT-2i therapy on the severity of outcomes in individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection...
March 27, 2024: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://read.qxmd.com/read/38536545/early-sevoflurane-sedation-in-severe-covid-19-related-lung-injury-patients-a-pilot-randomized-controlled-trial
#5
JOURNAL ARTICLE
Beatrice Beck-Schimmer, Erik Schadde, Urs Pietsch, Miodrag Filipovic, Seraina Dübendorfer-Dalbert, Patricia Fodor, Tobias Hübner, Reto Schuepbach, Peter Steiger, Sascha David, Bernard D Krüger, Thomas A Neff, Martin Schläpfer
BACKGROUND: This study aimed to assess a potential organ protective effect of volatile sedation in a scenario of severe inflammation with an early cytokine storm (in particular IL-6 elevation) in patients suffering from COVID-19-related lung injury with invasive mechanical ventilation and sedation. METHODS: This is a small-scale pilot multicenter randomized controlled trial from four tertiary hospitals in Switzerland, conducted between April 2020 and May 2021. 60 patients requiring mechanical ventilation due to severe COVID-19-related lung injury were included and randomized to 48-hour sedation with sevoflurane vs...
March 27, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38535673/a-3d-printed-portable-uv-and-visible-photoreactor-for-water-purification-and-disinfection-experiments
#6
JOURNAL ARTICLE
Nelson Castro, Joana M Queirós, Dinis C Alves, Margarida M Macedo Fernandes, Senetxu Lanceros-Méndez, Pedro M Martins
Water scarcity and contamination are urgent issues to be addressed. In this context, different materials, techniques, and devices are being developed to mitigate contemporary and forthcoming water constraints. Photocatalysis-based approaches are suitable strategies to address water contamination by degrading contaminants and eliminating microbes. Photoreactors are usually designed to perform photocatalysis in a scalable and standardised way. Few or none have been developed to combine these characteristics with portability, flexibility, and cost effectiveness...
March 15, 2024: Nanomaterials
https://read.qxmd.com/read/38535617/identifying-drivers-of-cost-in-pediatric-liver-transplantation
#7
JOURNAL ARTICLE
Divya Sabapathy, Kathleen Hosek, Fong W Lam, Moreshwar S Desai, Eric Williams, John Goss, Jean L Raphael, Michelle A Lopez
BACKGROUND & AIMS: Understanding the economics of pediatric liver transplantation (LT) is central to high-value care initiatives. We examined cost and resource utilization in pediatric LT nationally to identify drivers of cost and hospital factors associated with greater total cost of care. APPROACH & RESULTS: We reviewed 3295 children (<21 y) receiving a LT from 2010-2020 in the Pediatric Health Information System to study cost, both per LT and service-line, and associated mortality, complications and resource utilization...
March 27, 2024: Liver Transplantation
https://read.qxmd.com/read/38535563/lung-microbiota-and-ventilator-associated-pneumonia-in-the-neonatal-period
#8
REVIEW
Fermín García-Muñoz Rodrigo, Lourdes Urquía Martí, Marta Siguero Onrubia, Moreyba Borges Luján, Gloria Galán Henríquez, Desiderio Reyes Suárez
The lung microbiota is a complex community of microorganisms that colonize the respiratory tract of individuals from, or even before, birth. Although the lungs were traditionally believed to be sterile, recent research has shown that there is a diversity of bacterial species in the respiratory system. Knowledge about the lung microbiota in newborns and its relationship with bacterial infections is of vital importance to understand the pathogenesis of respiratory diseases in neonatal patients undergoing mechanical ventilation...
March 1, 2024: Pathogens
https://read.qxmd.com/read/38534990/safety-and-diagnostic-yield-of-medical-pleuroscopy-mp-performed-under-balanced-analgosedation-by-a-pneumological-team-compared-to-video-assisted-thoracic-surgery-vats-a-retrospective-controlled-real-life-study-torapo
#9
JOURNAL ARTICLE
Valentino Allocca, Luca Guidelli, Angela Galgano, Lucia Benedetti, Roberto Fabbroni, Andrea Bianco, Piero Paladini, Raffaele Scala
INTRODUCTION: Medical pleuroscopy (MP) is an invasive technique that provides access to the pleural space with a rigid or semi-rigid work instrument, allowing for visualization and the obtaining of bioptic pleural samples. Using pulmonologist-based analgosedation to perform pleuroscopy is still debated for safety reasons. The aim of this real-life study is to demonstrate the safety and diagnostic yield of MP performed under balanced analgosedation by a pulmonologist team with expertise in the management of critically ill patients in the respiratory intensive care unit (RICU) and interventional pulmonology unit as compared to video-assisted thoracic surgery (VATS) performed by a thoracic surgeon team under anesthesiologist-based analgosedation...
March 7, 2024: Diagnostics
https://read.qxmd.com/read/38534648/risk-factors-associated-with-mortality-in-acinetobacter-baumannii-infections-results-of-a-prospective-cohort-study-in-a-tertiary-public-hospital-in-guayaquil-ecuador
#10
JOURNAL ARTICLE
Luz Abarca-Coloma, Miguel Puga-Tejada, Tamara Nuñez-Quezada, Otilia Gómez-Cruz, Carlos Mawyin-Muñoz, Shivan Barungi, Macarena Perán
Antibiotic overuse and the resulting antimicrobial resistance pose significant global public health challenges, providing an avenue for opportunistic pathogens like Acinetobacter baumannii to thrive. This study will report the trends of Acinetobacter baumannii antimicrobial resistance patterns at the Hospital Teodoro Maldonado Carbo, Ecuador. An observational, analytical, longitudinal, and prospective study was conducted involving patients diagnosed with hospital-acquired infections. Antimicrobial susceptibility testing was performed, followed by molecular analysis of carbapenemase genes in Acinetobacter baumannii isolates...
February 23, 2024: Antibiotics
https://read.qxmd.com/read/38533695/factors-influencing-nurses-use-of-sedation-interruptions-in-a-critical-care-unit-a-descriptive-qualitative-study
#11
JOURNAL ARTICLE
Nicole D Graham, Ian D Graham, Brandi Vanderspank-Wright, Letitia Nadalin Penno, Dean A Fergusson, Janet E Squires
INTRODUCTION AND AIMS: This study examined critical care nurses', physicians', and allied health professionals' perceptions of factors that support, inhibit, or limit the use of sedation interruption (SI) to improve the use of this integral component of care for mechanically ventilated patients. METHOD: We conducted a theory-based, descriptive qualitative study using semi-structured interviews with critical care registered nurses, respiratory therapists, a pharmacist, and a physician in a hospital in Ontario, Canada...
March 28, 2024: JBI evidence implementation
https://read.qxmd.com/read/38533169/from-pansinusitis-to-cerebritis-due-to-eikenella-corrodens
#12
Adriana América Silva, Inês Zão, João A Louro, Eduarda Pereira, Elisabete Monteiro
Meningitis is a rare but possible complication of sinusitis. We present a case of a 21-year-old woman with a history of fever, headache and nasal obstruction who presented at the emergency department with psychomotor agitation. Orotracheal intubation and invasive mechanical ventilation were given to protect airway. Blood analysis showed leukocytosis and elevated C-reactive protein. Cerebral and maxillofacial computed tomography (CT) demonstrated pansinusitis with gas foci more prominent in the left frontal sinus with an area of ​​bone rarefaction on the posterior wall with possible communication with the cranial cavity...
February 2024: Curēus
https://read.qxmd.com/read/38532926/combined-frequency-domain-near-infrared-spectroscopy-and-diffuse-correlation-spectroscopy-system-for-comprehensive-metabolic-monitoring-of-inspiratory-muscles-during-loading
#13
JOURNAL ARTICLE
Carlos A Gómez, Laurent Brochard, Ewan C Goligher, Dmitry Rozenberg, W Darlene Reid, Darren Roblyer
SIGNIFICANCE: Mechanical ventilation (MV) is a cornerstone technology in the intensive care unit as it assists with the delivery of oxygen in critically ill patients. The process of weaning patients from MV can be long and arduous and can lead to serious complications for many patients. Despite the known importance of inspiratory muscle function in the success of weaning, current clinical standards do not include direct monitoring of these muscles. AIM: The goal of this project was to develop and validate a combined frequency domain near-infrared spectroscopy (FD-NIRS) and diffuse correlation spectroscopy (DCS) system for the noninvasive characterization of inspiratory muscle response to a load...
March 2024: Journal of Biomedical Optics
https://read.qxmd.com/read/38532618/extended-period-of-ventilation-before-delayed-cord-clamping-augments-left-to-right-shunting-and-decreases-systemic-perfusion-at-birth-in-preterm-lambs
#14
JOURNAL ARTICLE
Joseph J Smolich, Kelly R Kenna, Jonathan P Mynard
Previous studies have suggested that an extended period of ventilation before delayed cord clamping (DCC) augments birth-related rises in pulmonary arterial (PA) blood flow. However, it is unknown whether this greater rise in PA flow is accompanied by increases in left ventricular (LV) output and systemic arterial perfusion or whether it reflects enhanced left-to-right shunting across the ductus arteriosus and/or foramen ovale (FO), with decreased systemic arterial perfusion. Using an established preterm lamb birth transition model, this study compared the effect of a short (∼40 s, n = 11), moderate (∼2 min, n = 11) or extended (∼5 min, n = 12) period of initial mechanical lung ventilation before DCC on flow probe-derived perinatal changes in PA flow, LV output, total systemic arterial blood flow, ductal shunting and FO shunting...
March 26, 2024: Journal of Physiology
https://read.qxmd.com/read/38532586/-evaluation-of-safety-of-early-enteral-nutrition-in-patients-with-severe-intra-abdominal-infection-and-intestinal-fistulas
#15
JOURNAL ARTICLE
T Xie, C Chen, D L Yang, W Y Wang, F Chen, Y N He, P F Wang, Y S Li
Objective: To evaluate the safety of early enteral nutrition (EEN) support in patients with severe intra-abdominal infection and intestinal fistulas. Methods: This was a retrospective cohort study. We collected relevant clinical data of 204 patients with severe intra-abdominal infection and intestinal fistulas who had been managed in the No. 1 Department of General Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University between 1 January 2017 and 1 January 2020. The patients were allocated to EEN or delayed enteral nutrition (DEN) groups depending on whether enteral nutrition had been instituted within 48 hours of admission to the intensive care unit...
March 25, 2024: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38532405/lung-transcriptomics-reveals-the-underlying-mechanism-by-which-aerobic-training-enhances-pulmonary-function-in-chronic-obstructive-pulmonary-disease
#16
JOURNAL ARTICLE
Jian Li, Cai-Tao Chen, Peijun Li, Xiaoyun Zhang, Xiaodan Liu, Weibing Wu, Wei Gu
BACKGROUND: Aerobic training is the primary method of rehabilitation for improving respiratory function in patients with chronic obstructive pulmonary disease (COPD) in remission. However, the mechanism underlying this improvement is not yet fully understood. The use of transcriptomics in rehabilitation medicine offers a promising strategy for uncovering the ways in which exercise training improves respiratory dysfunction in COPD patients. In this study, lung tissue was analyzed using transcriptomics to investigate the relationship between exercise and lung changes...
March 26, 2024: BMC Pulmonary Medicine
https://read.qxmd.com/read/38532117/acute-sodium-bicarbonate-administration-improves-ventilatory-efficiency-in-experimental-respiratory-acidosis-clinical-implications
#17
JOURNAL ARTICLE
Horacio J Adrogué, Nicolaos E Madias
Administering sodium bicarbonate (NaHCO3 ) to patients with respiratory acidosis breathing spontaneously is contraindicated because it increases carbon dioxide load and depresses pulmonary ventilation. Nonetheless, several studies have reported salutary effects of NaHCO3 in patients with respiratory acidosis but the underlying mechanism remains uncertain. Considering that such reports have been ignored, we examined the ventilatory response of unanesthetized dogs with respiratory acidosis to hypertonic NaHCO3 infusion (1 N, 5 mmol/kg) and compared it with that of animals with normal acid-base status or one of the remaining acid-base disorders...
March 26, 2024: Pflügers Archiv: European Journal of Physiology
https://read.qxmd.com/read/38532048/awake-pronation-with-helmet-cpap-in-early-covid-19-ards-patients-effects-on-respiratory-effort-and-distribution-of-ventilation-assessed-by-eit
#18
JOURNAL ARTICLE
Tommaso Fossali, Martina Locatelli, Riccardo Colombo, Alice Veronese, Beatrice Borghi, Elisabetta Ballone, Antonio Castelli, Roberto Rech, Emanuele Catena, Davide Ottolina
Prone positioning with continuous positive airway pressure (CPAP) is widely used for respiratory support in awake patients with COVID-19-associated acute respiratory failure. We aimed to assess the respiratory mechanics and distribution of ventilation in COVID-19-associated ARDS treated by CPAP in awake prone position. We studied 16 awake COVID-19 patients with moderate-to-severe ARDS. The study protocol consisted of a randomized sequence of supine and prone position with imposed positive end-expiratory pressure (PEEP) of 5 and 10 cmH2 O delivered by helmet CPAP...
March 26, 2024: Internal and Emergency Medicine
https://read.qxmd.com/read/38531748/development-of-a-machine-learning-model-for-prediction-of-the-duration-of-unassisted-spontaneous-breathing-in-patients-during-prolonged-weaning-from-mechanical-ventilation
#19
JOURNAL ARTICLE
Sebastian Johannes Fritsch, Morris Riedel, Gernot Marx, Johannes Bickenbach, Andreas Schuppert
PURPOSE: Treatment of patients undergoing prolonged weaning from mechanical ventilation includes repeated spontaneous breathing trials (SBTs) without respiratory support, whose duration must be balanced critically to prevent over- and underload of respiratory musculature. This study aimed to develop a machine learning model to predict the duration of unassisted spontaneous breathing. MATERIALS AND METHODS: Structured clinical data of patients from a specialized weaning unit were used to develop (1) a classifier model to qualitatively predict an increase of duration, (2) a regressor model to quantitatively predict the precise duration of SBTs on the next day, and (3) the duration difference between the current and following day...
March 26, 2024: Journal of Critical Care
https://read.qxmd.com/read/38531747/perioperative-sildenafil-therapy-in-pulmonary-hypertension-associated-with-congenital-cardiac-disease-an-updated-meta-analysis
#20
REVIEW
Shajie Ur Rehman Usmani, Syed Umar Hasan, Syed Hasan Ali, Syeda Hoorulain Ahmed, Neha Pervez, Muhammad Danial, Owais Khan, Dominique L Tucker, M Mujeeb Zubair
To provide an updated meta-analysis to evaluate the efficacy and safety of sildenafil on pediatric patients with pulmonary hypertension (PH) associated with congenital heart disease (CHD). To assess the efficacy and safety of sildenafil, five outcomes, time duration of post-operative need for mechanical ventilation, time duration of post-operative ICU stay, length of hospitalization (LOH), the incidence of mortalities and pulmonary arterial pressure to aortic pressure ratio (PAP/AoP) were regarded as primary efficacy outcomes...
March 25, 2024: Asian Journal of Surgery
keyword
keyword
115308
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.