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"Vaginal lubrication"

M H Zahran, O Fahmy, A S El-Hefnawy, B Ali-El-Dein
OBJECTIVES: To evaluate the impact of radical cystectomy and urinary diversion on female sexual function. MATERIALS AND METHODS: A Medline search was conducted according to the PRISMA statement for all English full-text articles published between 1980 and 2016 and assessing female sexual function post radical cystectomy and urinary diversion. Eligible studies were subjected to critical analysis and revision. The primary outcomes were the reporting methods for female sexual dysfunction (FSD), manifestations of FSD, and factors associated with FSD, postoperative recoverability of FSD, and awareness level regarding FSD...
September 20, 2016: Climacteric: the Journal of the International Menopause Society
Akiva P Novetsky, Marla J Keller, Ana Gradissimo, Zigui Chen, Stephanie L Morgan, Xiaonan Xue, Howard D Strickler, José A Fernández-Romero, Robert Burk, Mark H Einstein
OBJECTIVE: To assess in vitro efficacy of Divine 9, a carrageenan-based vaginal lubricant that is being studied as a microbicide to inhibit HPV16 pseudovirus (PsV) infection. METHODS: Sexually active US women between 19 and 35years without prior HPV vaccination or cervical intraepithelial neoplasia were instructed to use Divine 9 vaginally with an applicator either before sex only or before and after intercourse. Women who applied a single dose of gel returned for cervicovaginal lavage (CVL) collection 1, 4 or 8-12h after intercourse versus those who applied gel before and after intercourse returned 1, 4 or 8-12h after the second gel dose...
September 10, 2016: Gynecologic Oncology
Cheryl B Iglesia
PURPOSE OF REVIEW: The purpose of this review is to describe new terminology for vulvovaginal atrophy and female sexual dysfunction and to highlight recent findings related to vaginal moisturizers, lubricants and prescription estrogen preparations. RECENT FINDINGS: Sexual health is a marker for overall health. A minority (40%) of healthcare providers routinely ask about sexual problems and its impact on quality of life. New terminology by the American Psychiatric Association divides female sexual disorders into three categories: arousal/interest disorder, orgasmic disorder and genital pain and penetration disorder...
October 2016: Current Opinion in Obstetrics & Gynecology
Klemens Winder, Ralf A Linker, Frank Seifert, Martina Deutsch, Tobias Engelhorn, Arnd Dörfler, De-Hyung Lee, Katharina M Hösl, Max J Hilz
OBJECTIVE: This study intended to determine associations between alterations of female sexual arousal as well as vaginal lubrication and the site of cerebral multiple sclerosis (MS) lesions. METHODS: In 44 women with MS (mean age: 36.5 ± 9.9 years), we assessed their medical history and evaluated sexual function using the Female Sexual Function Index scores for arousal and vaginal lubrication. We determined potential confounding factors of sexual dysfunction: age; disease duration; physical disability; depression; bladder or urinary dysfunction; and total volume of cerebral lesions...
October 2016: Annals of Neurology
Martha Hickey, Jennifer L Marino, Sabine Braat, Swee Wong
Discomfort during sexual activity is common after breast cancer. Vaginal estrogens are effective but commonly avoided due to systemic absorption. Despite the large commercial market for vaginal lubricants, no randomized studies have compared products. We aimed to compare efficacy and acceptability of two major types of lubricant for discomfort during sexual activity in postmenopausal breast cancer patients. In a single-center, randomized, double-blind, AB/BA crossover design, sexually active postmenopausal breast cancer patients used each lubricant for 4 weeks...
July 2016: Breast Cancer Research and Treatment
Kyung-Jin Oh, Hyun-Suk Lee, Kyuyoun Ahn, Kwangsung Park
Background. The objectives of this study were to investigate the localization of tight junctions and the modulation of zonula occludens- (ZO-) 1, occludin and claudin-1 expression by estrogen in castrated female rat vagina. Female Sprague-Dawley rats (230-240 g, n = 45) were divided into three groups and subjected to a sham operation (control group, n = 15), bilateral ovariectomy (Ovx group, n = 15), or bilateral ovariectomy followed by daily subcutaneous injection of 17β-estradiol (50 μg/kg/day, Ovx + Est group, n = 15)...
2016: BioMed Research International
Qing Sun, Jiehong Huang, Yong-Jian Yue, Jian-Bang Xu, Ping Jiang, Deng-Liang Yang, Yong Zeng, Wen-Liang Zhou
INTRODUCTION: Hydrogen sulfide (H2S) plays a large role in female and male sexual responses characterized by a smooth muscle relaxant effect. Moreover, H2S is a novel pro-secretory neuromodulator that modulates epithelial ion transport. However, whether H2S has a role in regulating vaginal epithelial ion transport and fluid secretion has not been extensively studied. AIM: To identify the effects of H2S on vaginal epithelial ion transport and lubrication in an exploratory investigation...
May 2016: Journal of Sexual Medicine
Sóstenes Postigo, Sônia Maria Rolim Rosa Lima, Silvia Saito Yamada, Benedito Fabiano dos Reis, Gustavo Maximiliano Dutra da Silva, Tsutomu Aoki
OBJECTIVE: The aim of this study was to study the effects of Tribulus terrestris on sexual function in menopausal women. METHODS: This was a prospective, randomized, double-blind, placebo-controlled clinical trial that included 60 postmenopausal women with sexual dysfunction. The women were divided into two groups, placebo group and Tribulus group, and evaluated by using the Sexual Quotient-female version (SQ-F) and Female Intervention Efficacy Index (FIEI) questionnaires...
March 2016: Revista Brasileira de Ginecologia e Obstetrícia
Hongying He, Zhijun Yang, Jieqing Zhang, Desheng Yao, Jiangtao Fan, Renfeng Zhao, Dingyuan Zeng, Xiaoxia Hu, Zhong Lin, Yanming Jiang, Li Li
OBJECTIVE: To evaluate the short- term and long- term outcomes after laparoscopic surgery compared with traditional laparotomy in patients with stage I-II endometrial cancer. METHODS: A retrospective study of population among 673 patientsfor early-stage endometrial cancer between Jan. 2007 and May 2014 was involved from 6 third-grade class-A communal hospitals in Guangxi. Three hundred and seventy-six cases were performed by laparoscopy, 297 cases by laparotomy...
December 2015: Zhonghua Fu Chan Ke za Zhi
J Di Marco, C De Broglie, P Manceau, L Weglinski, F Le Breton, D Verrollet, G Amarenco
AIM: Determine if the initiation of an anticholinergic treatment affects the sexual function in women diagnosed with multiple sclerosis (MS). METHODS: It was a single-centre prospective open label study on 18 women affected by MS, with a clinical overactive bladder syndrome, and examined before and after anticholinergic treatment. Several variables were studied before and after treatment: the total anticholinergic load (Anticholinergic Drug Scale [ADS]), the Female Sexual Function Index, the Urinary Symptom Profile (USP) and functional status (EDSS, MIF)...
March 2016: Progrès en Urologie
D Edwards, N Panay
Vaginal dryness is a common condition that is particularly prevalent during and after the menopause, and is one of the symptoms of vulvovaginal atrophy/genitourinary syndrome of menopause. The impact of vaginal dryness on interpersonal relationships, quality of life, daily activities, and sexual function can be significant, but is frequently underestimated. Furthermore, barriers exist to treatment-seeking, and this condition is often underreported and undertreated. Greater education about vaginal dryness and the range of available treatments is essential to encourage more women to seek help for this condition...
April 2016: Climacteric: the Journal of the International Menopause Society
Suzanne Lindström, Linda J Kvist
BACKGROUND: Problems related to pain during vaginal penetration are complex and the etiology is multi-factorial. It was the aim of the present study to measure whether treatment using desensitization exercises and cognitive behavioral therapy (CBT) for women with provoked vulvodynia (PVD) could increase sexual interest, sexual satisfaction and response whilst decreasing experiences of sexual pain. METHODS AND OUTCOME MEASURES: Sixty women suffering from PVD were treated during a 10-week period with a combination of mucosal desensitization and pelvic floor exercises and CBT...
2015: BMC Women's Health
Giacomo Ciocca, Judith Usall, Montse Dolz, Erika Limoncin, Giovanni L Gravina, Eleonora Carosa, Bernardo Sánchez, Ana Barajas, Iris Baños, Elena Huerta, Aida Farreny, Camilla Franchi, Genipe Group, Susana Ochoa
AIM: Patients with chronic mental disorders often can suffer from sexual dysfunction. Nevertheless, the sexual functioning of new patients with first-episode psychosis has been little explored. The aim of this study was to investigate gender differences in sexual functioning in people with first-episode psychosis. METHODS: A group of 40 males and 37 females with first-episode psychosis took part in the research. We administered a psychiatric protocol composed of the PANSS, UKU and SCID-DSM-IV diagnosis...
September 2015: Rivista di Psichiatria
Santiago Palacios, Andrea Mejias
INTRODUCTION: Vasomotor symptoms (VMS) and the genitourinary syndrome of menopause (GSM) are recognized as the most frequent and bothersome symptoms associated with menopause. There are different treatments for both groups of symptoms, being necessary to individualize them. AREAS COVERED: There are different therapies for VMS including hormonal treatments with estrogen, with and without progestins; the new alternative, tissue-selective estrogen complex (TSEC), tibolone, phytoestrogens and only progestins...
2015: Expert Opinion on Pharmacotherapy
Rochelle K Rosen, Jacob J van den Berg, Sara E Vargas, Natali Senocak, Julia G Shaw, Robert W Buckheit, Kelley Alison Smith, Kate Morrow Guthrie
OBJECTIVE: Users' sensory perceptions and experiences of intravaginal products can inform acceptability and adherence. Focusing on the meanings women derive from formulation/device characteristics facilitates developers' design iterations toward optimizing user experience. We investigated how users of long-acting gels and intravaginal rings (IVRs) impute meaning to characteristics that may affect future product use. STUDY DESIGN: Focus groups were conducted with contraceptive IVR and vaginal lubricant users...
December 2015: Contraception
Min Y Lee, Amanda Dalpiaz, Richard Schwamb, Yimei Miao, Wayne Waltzer, Ali Khan
The Bartholin's glands are located symmetrically at the posterior region of the vaginal opening and play an important role in the female reproductive system. These two pea-sized glands are involved in mucus secretion and vaginal lubrication. Cyst formation in the glands is common and results from mucus build-up in gland ducts. It is important to monitor such cysts because they may occur in the form of carcinomas. Larger cysts and abscesses are found in the lower vestibular region and typically present with erythema and edema...
May 2015: Current Urology
Frédérique Courtois, Kathleen Charvier
Many aspects of sexuality can be disrupted following a spinal cord lesion (SCL). It can alter an individual's self-esteem and body image, interfere with positioning and mobility, introduce unexpected problems with incontinence and spasticity, decrease pleasure, and delay orgasm. Sexual concerns in men can involve erectile function, essential for intercourse, ejaculation function, necessary for fertility, and the ability to reach orgasm. In women they can involve concerns with vaginal lubrication, genital congestion, and vaginal infections, which can all go unnoticed, and orgasm, which may be lost...
2015: Handbook of Clinical Neurology
Simon Podnar, David B Vodušek
Peripheral nervous system (PNS) disorders may cause sexual dysfunction (SD) in patients of both genders. These disorders include mainly polyneuropathies (particularly those affecting the autonomic nervous system (ANS)) and localized lesions affecting the innervation of genital organs. Impaired neural control may produce a malfunction of the genital response consisting of loss of genital sensitivity, erectile dysfunction, loss of vaginal lubrication, ejaculation disorder, and orgasmic disorder. In addition, there is often a loss of desire which actually has a complex pathogenesis, which goes beyond the mere loss of relevant nerve function...
2015: Handbook of Clinical Neurology
Arif Kokcu, Emel Kurtoglu, Devran Bildircin, Handan Celik, Aysegul Kaya, Tayfun Alper
INTRODUCTION: Hysterectomy is the most common major gynecologic operation, together with bilateral salpingo-oophorectomy in the majority of women over the age of 45. AIM: To investigate whether surgical menopause affects female sexual performance differently from natural menopause. METHODS: The study included 121 women who had undergone surgical menopause and 122 women who had undergone natural menopause. All the women had similar economic, sociocultural, and personal demographic profiles, had been postmenopausal for at least 1 year, and were between the ages of 45 and 65...
June 2015: Journal of Sexual Medicine
Parastou Rad, Mitra Tadayon, Mohammadreza Abbaspour, Seyed Mahmood Latifi, Iran Rashidi, Hamdollah Delaviz
BACKGROUND: Most of the women suffer from vaginal atrophy and dryness, and therefore, efficient and safe treatment is needed to improve vaginal lubrication. Vitamin D has several important functions which may be effective in proliferation and repair of the epithelial tissue. This study aimed to evaluate the effect of vitamin D vaginal suppositories on maturation index, pH, and dryness in postmenopausal women. MATERIALS AND METHODS: Women were enrolled in this double-blind clinical trial, in whom menopause occurred at least one year ago...
March 2015: Iranian Journal of Nursing and Midwifery Research
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