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https://www.readbyqxmd.com/read/29202940/genitourinary-syndrome-of-menopause-management-strategies-for-the-clinician
#1
REVIEW
Stephanie S Faubion, Richa Sood, Ekta Kapoor
Genitourinary syndrome of menopause (GSM), previously known as atrophic vaginitis or vulvovaginal atrophy, affects more than half of postmenopausal women. Caused by low estrogen levels after menopause, it results in bothersome symptoms, including vaginal dryness, itching, dyspareunia, urinary urgency and increased frequency, and urinary tract infections. Even though women with GSM can have sexual dysfunction that interferes with partner relationships, women are often embarrassed to seek treatment, and health care professionals do not always actively screen for GSM...
December 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29140150/radiotherapy-for-cervical-cancer-impact-on-the-vaginal-epithelium-and-sexual-function
#2
Alexandra Hofsjö, Karin Bergmark, Bo Blomgren, Helen Jahren, Nina Bohm-Starke
BACKGROUND: Women who have been treated for cervical cancer have persistent changes in their sexual function, which result in considerable distress. The aim of this study was to investigate the morphology of the vaginal epithelium in cervical cancer survivors treated with radiotherapy and its correlation to serum levels of sex steroid hormones and sexual function. MATERIAL AND METHODS: We included 34 patients treated for cervical cancer with radiotherapy and 37 healthy age-matched control women scheduled for benign gynecological surgery...
November 15, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29082366/women-s-orgasm-obstacles-a-qualitative-study
#3
Maryam Nekoolaltak, Zohreh Keshavarz, Masoumeh Simbar, Ali Mohammad Nazari, Ahmad Reza Baghestani
BACKGROUND: Woman's orgasm plays a vital role in sexual compatibility and marital satisfaction. Orgasm in women is a learnable phenomenon that is influenced by several factors. OBJECTIVE: The aim of this study is exploring obstacles to orgasm in Iranian married women. MATERIALS AND METHODS: This qualitative study with directed content analysis approach was conducted in 2015-2016, on 20 Iranian married women who were individually interviewed at two medical clinics in Tehran, Iran...
August 2017: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/29067688/the-evidence-for-laser-treatments-to-the-vulvo-vagina-making-sure-we-do-not-repeat-past-mistakes
#4
REVIEW
Sophia Song, Aaron Budden, Asha Short, Erin Nesbitt-Hawes, Rebecca Deans, Jason Abbott
Following menopause, up to 49% of women will experience genitourinary symptoms such as vaginal itching, dryness, dyspareunia and incontinence as a result of oestrogen deficiency. Treatments such as vaginal lubricants and moisturisers only temporarily relieve symptoms, while local oestrogen treatments are often unacceptable or unsafe for many women. Recently, a novel laser treatment has been proposed as a non-invasive, long-term solution to vulvo-vaginal and urinary symptoms. While preliminary histological results have been promising, its therapeutic, clinical effect has yet to be determined...
October 25, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29023137/sexual-vs-nonsexual-currently-most-upsetting-trauma-a-fresh-look-at-attenuation-of-sexual-response-alcohol-intoxication-and-post-traumatic-stress
#5
Elizabeth R Bird, Martin Seehuus, Julia R Heiman, Kelly Cue Davis, Jeanette Norris, William H George
This study examined the dependence of sexual response (vaginal pulse amplitude [VPA] and subjective sexual arousal) on alcohol intoxication (.10% breath alcohol concentration [BrAC] versus no alcohol) and the nature of a woman's currently most upsetting traumatic event (C-MUTE), whether it was sexual (e.g., rape) or nonsexual (e.g., combat). Self-reported sexual outcomes were also compared by C-MUTE type. A total of 117 women completed background measures and either drank alcoholic or nonalcoholic beverages...
October 12, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28877113/sexual-experiences-of-chinese-patients-living-with-an-ostomy
#6
Xiaomei Zhu, Yongyi Chen, Xinhui Tang, Yupan Chen, Yangyu Liu, Wei Guo, Aizhong Liu
PURPOSE: The purpose of this study was to examine the sexual experience of Chinese patients with ostomy and associated factors. DESIGN: A prospective descriptive study using self-report questionnaires. SUBJECTS AND SETTING: Seventy-five Chinese participants who underwent ostomy surgery in a large cancer specialist hospital in the Hunan province between 2008 and 2013. METHODS: Data were collected face-to-face by the investigators in an outpatient setting from 75 participants who completed the Arizona Sexual Experience Inventory Scale (ASEX)...
September 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28547655/sexual-health-needs-and-educational-intervention-preferences-for-women-with-cancer
#7
Cara Stabile, Shari Goldfarb, Raymond E Baser, Deborah J Goldfrank, Nadeem R Abu-Rustum, Richard R Barakat, Maura N Dickler, Jeanne Carter
PURPOSE: To assess sexual/vaginal health issues and educational intervention preferences in women with a history of breast or gynecologic cancer. METHODS: Patients/survivors completed a cross-sectional survey at their outpatient visits. Main outcome measures were sexual dysfunction prevalence, type of sexual/vaginal issues, awareness of treatments, and preferred intervention modalities. Descriptive frequencies were performed, and results were dichotomized by age, treatment status, and disease site...
August 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28492016/vaginal-rejuvenation-using-energy-based-devices
#8
REVIEW
Cheryl Karcher, Neil Sadick
Physiologic changes in a woman's life, such as childbirth, weight fluctuations, and hormonal changes due to aging and menopause, may alter the laxity of the vaginal canal, damage the pelvic floor, and devitalize the mucosal tone of the vaginal wall. These events often lead to the development of genitourinary conditions such as stress urinary incontinence; vaginal atrophy; dryness; and physiologic distress affecting a woman's quality of life, self-confidence, and sexuality. Various treatment modalities are currently available to manage these indications, varying from invasive vaginal surgery to more benign treatments like topical vaginal hormonal gels or hormone-replacement therapy...
September 2016: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28419911/safety-and-long-term-efficacy-of-fractional-co2-laser-treatment-in-women-suffering-from-genitourinary-syndrome-of-menopause
#9
Fariba Behnia-Willison, Sara Sarraf, Joseph Miller, Behrang Mohamadi, Alison S Care, Alan Lam, Nadia Willison, Leila Behnia, Stefano Salvatore
OBJECTIVES: To evaluate the safety and long-term efficacy of fractional CO2 laser treatment in reducing the severity of symptoms of genitourinary syndrome of menopause (GSM) in menopausal women. STUDY DESIGN: 102 women presenting with symptomatic GSM were treated with the fractional CO2 laser (MonaLisa Touch, DEKA) system across a series of treatments delivered at intervals of six or more weeks. The Australian Pelvic Floor Questionnaire was used to gather data on sexual function and side-effects at three time-points across the study period (prospective panel design study)...
April 2, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28240966/efficacy-of-internet-based-cognitive-behavioral-therapy-in-improving-sexual-functioning-of-breast-cancer-survivors-results-of-a-randomized-controlled-trial
#10
RANDOMIZED CONTROLLED TRIAL
Susanna B Hummel, Jacques J D M van Lankveld, Hester S A Oldenburg, Daniela E E Hahn, Jacobien M Kieffer, Miranda A Gerritsma, Marianne A Kuenen, Nina Bijker, Paul J Borgstein, Gijsbert Heuff, Alexander M F Lopes Cardozo, Peter W Plaisier, Herman Rijna, Suzan van der Meij, Eric J van Dulken, Bart C Vrouenraets, Eva Broomans, Neil K Aaronson
Purpose We evaluated the effect of Internet-based cognitive behavioral therapy (CBT) on sexual functioning and relationship intimacy (primary outcomes) and body image, menopausal symptoms, marital functioning, psychological distress, and health-related quality of life (secondary outcomes) in breast cancer survivors (BCSs) with a DSM-IV diagnosis of a sexual dysfunction. Patients and Methods We randomly assigned 169 BCSs to either Internet-based CBT or a waiting-list control group. The CBT consisted of weekly therapist-guided sessions, with a maximum duration of 24 weeks...
April 20, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28229275/a-pilot-randomized-trial-to-prevent-sexual-dysfunction-in-postmenopausal-breast-cancer-survivors-starting-adjuvant-aromatase-inhibitor-therapy
#11
RANDOMIZED CONTROLLED TRIAL
Pragati Advani, Abenaa M Brewster, George P Baum, Leslie R Schover
PURPOSE: A randomized pilot trial evaluated the hypothesis that early intervention lessens sexual dysfunction in the first year on aromatase inhibitors. A secondary aim was comparing the efficacy of two vaginal moisturizers. METHODS: Fifty-seven postmenopausal women with early stage breast cancer starting aromatase inhibitors were randomized to three treatment groups. All received a handout on managing sexual and other side effects. The Usual Care group received no additional therapy...
August 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28080186/satisfaction-with-sex-life-in-sexually-active-heterosexual-couples-dealing-with-breast-cancer-a-nationwide-longitudinal-study
#12
Nina Rottmann, Dorte Gilså Hansen, René dePont Christensen, Mariët Hagedoorn, Morten Frisch, Anne Nicolaisen, Niels Kroman, Henrik Flyger, Christoffer Johansen
BACKGROUND: A breast cancer (BC) diagnosis can profoundly affect the sex life of patient and partner within a couple. The purpose of the present study is to examine whether individual and partner sexual functioning, affectionate behavior, emotional closeness and depressive symptoms are associated with change over time in satisfaction with sex life of sexually active heterosexual couples dealing with BC and to explore whether the associations differ between patients and partners after adjustment for basic sociodemographic characteristics, comorbidity and BC treatment...
February 2017: Acta Oncologica
https://www.readbyqxmd.com/read/27981170/evaluating-sexual-nursing-care-intervention-for-reducing-sexual-dysfunction-in-indonesian-cervical-cancer-survivors
#13
Yati Afiyanti, Imami Nur Rachmawati, Ariesta Milanti
OBJECTIVE: This study aims to describe the factors affecting successful nursing care intervention on sexuality. METHODS: A one-group pre- and post-test design was used. Fifty-three cervical cancer survivors and their spouses were administered with nursing care intervention on sexuality in three sessions and evaluated after 6 weeks. RESULTS: Sexual intervention reduced dyspareunia symptoms, improved vaginal lubrication, improved sexual satisfaction, and enhanced sexual arousal, sexual desire, and orgasm among cancer survivors and their spouses...
July 2016: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/27918337/the-effects-of-a-genital-vibratory-stimulation-device-on-sexual-function-and-genital-sensation
#14
Marsha K Guess, Kathleen A Connell, Scott Chudnoff, Olusola Adekoya, Cherrilyn Richmond, Kayla E Nixon, Katherine Freeman, Arnold Melman
OBJECTIVE: The aim of this study was to evaluate the effectiveness of a genital vibratory stimulation device in improving sexual function in women with arousal and orgasm disorders. METHODS: In this single-arm, prospective study, baseline and 1- and 3-month assessments were performed to evaluate women with sexual arousal and/or orgasmic disorders, who received therapy using a genital vibratory stimulation device. Sexual function, satisfaction, and distress were evaluated using the Female Sexual Function Index (FSFI), the Female Sexual Distress Scale, and the Female Intervention Efficacy Index questionnaires...
July 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27649461/female-sexual-dysfunction-post-radical-cystectomy-and-urinary-diversion
#15
REVIEW
M H Zahran, O Fahmy, A S El-Hefnawy, B Ali-El-Dein
OBJECTIVES: To evaluate the impact of radical cystectomy and urinary diversion on female sexual function. MATERIALS AND METHODS: A Medline search was conducted according to the PRISMA statement for all English full-text articles published between 1980 and 2016 and assessing female sexual function post radical cystectomy and urinary diversion. Eligible studies were subjected to critical analysis and revision. The primary outcomes were the reporting methods for female sexual dysfunction (FSD), manifestations of FSD, and factors associated with FSD, postoperative recoverability of FSD, and awareness level regarding FSD...
December 2016: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/27625046/in-vitro-inhibition-of-human-papillomavirus-following-use-of-a-carrageenan-containing-vaginal-gel
#16
Akiva P Novetsky, Marla J Keller, Ana Gradissimo, Zigui Chen, Stephanie L Morgan, Xiaonan Xue, Howard D Strickler, José A Fernández-Romero, Robert Burk, Mark H Einstein
OBJECTIVE: To assess in vitro efficacy of Divine 9, a carrageenan-based vaginal lubricant that is being studied as a microbicide to inhibit HPV16 pseudovirus (PsV) infection. METHODS: Sexually active US women between 19 and 35years without prior HPV vaccination or cervical intraepithelial neoplasia were instructed to use Divine 9 vaginally with an applicator either before sex only or before and after intercourse. Women who applied a single dose of gel returned for cervicovaginal lavage (CVL) collection 1, 4 or 8-12h after intercourse versus those who applied gel before and after intercourse returned 1, 4 or 8-12h after the second gel dose...
November 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27517339/what-s-new-in-the-world-of-postmenopausal-sex
#17
Cheryl B Iglesia
PURPOSE OF REVIEW: The purpose of this review is to describe new terminology for vulvovaginal atrophy and female sexual dysfunction and to highlight recent findings related to vaginal moisturizers, lubricants and prescription estrogen preparations. RECENT FINDINGS: Sexual health is a marker for overall health. A minority (40%) of healthcare providers routinely ask about sexual problems and its impact on quality of life. New terminology by the American Psychiatric Association divides female sexual disorders into three categories: arousal/interest disorder, orgasmic disorder and genital pain and penetration disorder...
October 2016: Current Opinion in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27464008/neuroanatomic-correlates-of-female-sexual-dysfunction-in-multiple-sclerosis
#18
Klemens Winder, Ralf A Linker, Frank Seifert, Martina Deutsch, Tobias Engelhorn, Arnd Dörfler, De-Hyung Lee, Katharina M Hösl, Max J Hilz
OBJECTIVE: This study intended to determine associations between alterations of female sexual arousal as well as vaginal lubrication and the site of cerebral multiple sclerosis (MS) lesions. METHODS: In 44 women with MS (mean age: 36.5 ± 9.9 years), we assessed their medical history and evaluated sexual function using the Female Sexual Function Index scores for arousal and vaginal lubrication. We determined potential confounding factors of sexual dysfunction: age; disease duration; physical disability; depression; bladder or urinary dysfunction; and total volume of cerebral lesions...
October 2016: Annals of Neurology
https://www.readbyqxmd.com/read/27306420/a-randomized-double-blind-crossover-trial-comparing-a-silicone-versus-water-based-lubricant-for-sexual-discomfort-after-breast-cancer
#19
Martha Hickey, Jennifer L Marino, Sabine Braat, Swee Wong
Discomfort during sexual activity is common after breast cancer. Vaginal estrogens are effective but commonly avoided due to systemic absorption. Despite the large commercial market for vaginal lubricants, no randomized studies have compared products. We aimed to compare efficacy and acceptability of two major types of lubricant for discomfort during sexual activity in postmenopausal breast cancer patients. In a single-center, randomized, double-blind, AB/BA crossover design, sexually active postmenopausal breast cancer patients used each lubricant for 4 weeks...
July 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27127786/estrogen-modulates-expression-of-tight-junction-proteins-in-rat-vagina
#20
Kyung-Jin Oh, Hyun-Suk Lee, Kyuyoun Ahn, Kwangsung Park
Background. The objectives of this study were to investigate the localization of tight junctions and the modulation of zonula occludens- (ZO-) 1, occludin and claudin-1 expression by estrogen in castrated female rat vagina. Female Sprague-Dawley rats (230-240 g, n = 45) were divided into three groups and subjected to a sham operation (control group, n = 15), bilateral ovariectomy (Ovx group, n = 15), or bilateral ovariectomy followed by daily subcutaneous injection of 17β-estradiol (50 μg/kg/day, Ovx + Est group, n = 15)...
2016: BioMed Research International
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