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https://www.readbyqxmd.com/read/29161600/monitoring-wastewater-for-assessing-community-health-sewage-chemical-information-mining-scim
#1
Christian G Daughton
Timely assessment of the aggregate health of small-area human populations is essential for guiding the optimal investment of resources needed for preventing, avoiding, controlling, or mitigating human exposure risks, as well as for maintaining or promoting health. Seeking those interventions yielding the greatest benefit with respect to the allocation of resources is critical for making progress toward community sustainability, reducing health disparities, promoting social justice, and maintaining or improving collective health and well-being...
November 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29161582/the-role-of-emotional-clarity-and-distress-tolerance-in-deliberate-self-harm-in-a-sample-of-trauma-exposed-inpatient-adolescents-at-risk-for-suicide
#2
Andres G Viana, Emma C Woodward, Elizabeth M Raines, Abigail E Hanna, Michael J Zvolensky
OBJECTIVE: The purpose of this study was to examine distress tolerance as a moderator of the relationship between emotional clarity and deliberate self-harm (DSH) in a diverse sample of trauma-exposed adolescents in acute psychiatric care at high risk of suicidal behavior. It was hypothesized that distress tolerance would emerge as a significant moderator, such that the association between emotional clarity and DSH would be significant among youth with high, but not low, distress tolerance...
October 28, 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29160843/public-and-healthcare-professionals-knowledge-and-attitudes-toward-binge-eating-disorder-a-narrative-review
#3
REVIEW
Deborah Lynn Reas
Binge eating disorder (BED) is characterized by recurrent binge eating and marked distress in the absence of inappropriate compensatory behaviors for weight control. BED is prevalent in men and women, is associated with elevated psychosocial and functional impairment, and is associated strongly with obesity and related medical comorbidities. The aim is to provide a brief, state-of-the-art review of the major and recent findings to inform educational and awareness campaigns, stigma reduction interventions, as well as current clinical practice and future research...
November 21, 2017: Nutrients
https://www.readbyqxmd.com/read/29160072/solvent-controlled-branching-of-localized-versus-delocalized-singlet-exciton-states-and-equilibration-with-charge-transfer-in-a-structurally-well-defined-tetracene-dimer
#4
Jasper D Cook, Thomas J Carey, Dylan H Arias, Justin C Johnson, Niels H Damrauer
A detailed photophysical picture is elaborated for a structurally well-defined and symmetrical bis-tetracene dimer in solution. The molecule was designed for interrogation of the initial photophysical steps (S1 → (1)TT) in intramolecular singlet fission (SF). (Triisopropylsilyl)acetylene substituents on the dimer TIPS-BT1 as well as a monomer model TIPS-Tc enable a comparison of photophysical properties, including transient absorption dynamics, as solvent polarity is varied. In nonpolar toluene solutions, TIPS-BT1 decays via radiative and nonradiative pathways to the ground state with no evidence for dynamics related to the initial stages of SF...
November 21, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29160067/molecular-tension-probes-for-imaging-forces-at-the-cell-surface
#5
Yang Liu, Kornelia Galior, Victor Pui-Yan Ma, Khalid Salaita
Mechanical forces are essential for a variety of biological processes ranging from transcription and translation to cell adhesion, migration, and differentiation. Through the activation of mechanosensitive signaling pathways, cells sense and respond to physical stimuli from the surrounding environment, a process widely known as mechanotransduction. At the cell membrane, many signaling receptors, such as integrins, cadherins and T- or B-cell receptors, bind to their ligands on the surface of adjacent cells or the extracellular matrix (ECM) to mediate mechanotransduction...
November 21, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29159874/meta-synthesis-on-migraine-management
#6
REVIEW
Mia T Minen, Lita Anglin, Alexandra Boubour, Allison Squires, Linda Herrmann
BACKGROUND: Migraine is one of the top 10 most disabling conditions among adults worldwide. Most migraine research is quantitative and indicates concerns about medication adherence, stigma, and more. Qualitative studies might reveal an improved understanding of migraine patients' perspectives regarding migraine treatment. OBJECTIVE: The aim of this study was to synthesize the qualitative research on migraine patients' perspectives regarding migraine treatment to (a) identify common patterns across various types of migraine treatment studies and (b) inform future research...
November 21, 2017: Headache
https://www.readbyqxmd.com/read/29158580/ck2-regulates-5-ht4-receptor-signaling-and-modulates-depressive-like-behavior
#7
J Castello, B LeFrancois, M Flajolet, P Greengard, E Friedman, H Rebholz
The serotonergic neurotransmitter system has been widely implicated in the pathophysiology of mood-related disorders such as anxiety and major depressive disorder (MDD). The onset of therapeutic efficacy of traditional antidepressants is delayed by several weeks. The 5-HT4 receptor has emerged as a new therapeutic target since agonists of this receptor induce rapid antidepressant-like responses in rodents. Here we show that the 5-HT4 receptor is regulated by CK2, at transcriptional and post-transcriptional levels...
November 21, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/29158382/active-turbulence-in-a-gas-of-self-assembled-spinners
#8
Gašper Kokot, Shibananda Das, Roland G Winkler, Gerhard Gompper, Igor S Aranson, Alexey Snezhko
Colloidal particles subject to an external periodic forcing exhibit complex collective behavior and self-assembled patterns. A dispersion of magnetic microparticles confined at the air-liquid interface and energized by a uniform uniaxial alternating magnetic field exhibits dynamic arrays of self-assembled spinners rotating in either direction. Here, we report on experimental and simulation studies of active turbulence and transport in a gas of self-assembled spinners. We show that the spinners, emerging as a result of spontaneous symmetry breaking of clock/counterclockwise rotation of self-assembled particle chains, generate vigorous vortical flows at the interface...
November 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29158014/movement-patterns-in-entomopathogenic-nematodes-continuous-vs-temporal
#9
Wei-Bin Ruan, David Shapiro-Ilan, Edwin E Lewis, Fatma Kaplan, Hans Alborn, Xin-Hui Gu, Paul Schliekelman
To exploit resources, animals implement various foraging behaviors to increase their fitness. Entomopathogenic nematodes are obligate parasites of insects in nature. In previous studies, entomopathogenic nematodes were reported to exhibit group movement behavior in the presence and absence of insect hosts. However, it was not determined if group movement is continuous or temporal. For example, nematode movement behavior upon emergence from the host might start out in an independent fashion prior to aggregation, or group movement may be exhibited continuously...
November 17, 2017: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/29157764/perianesthesia-nurses-are-my-second-family-a-qualitative-descriptive-study
#10
Julanne Seefeldt, Stacey Wood, Pamela Bolton, Tara Fitzpatrick, Kristin Stegenga, Cristine Roberts
PURPOSE: Identify the perceptions of perianesthesia nurses regarding behaviors that promote or detract from sustaining a safe, efficient, and satisfying work environment. DESIGN: Two focus groups and seven individual interviews (n=14) were conducted exploring the perceptions regarding team behavior of registered nurses in one pediatric perianesthesia unit. METHODS: Qualitative descriptive data collection, inductive content analysis. FINDINGS: Nurses described a responsive, engaged health care team whose leadership is available and directive when needed, as creating an effective, satisfying work environment...
December 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/29157598/chinese-vietnamese-and-asian-indian-parents-perspectives-about-well-child-visits-a-qualitative-analysis
#11
Maya Ragavan, Wendy Li, A Rani Elwy, John Cowden, Megan Bair-Merritt
OBJECTIVES: Well-child visits are a critical component of pediatric healthcare; however, disparities in attendance and quality of care exist for Asian children. Limited research has explored Asian immigrant parents' perspectives about their well-child visit experience. METHODS: Qualitative interviews were conducted with Chinese, Vietnamese, and Asian Indian immigrant parents. Participants were recruited from community-based organizations in the Boston area. Interviews focused on parents' perceptions about well-child visits, including individual attitudes, social and cultural factors impacting their opinions, perceived behavioral control, and improving visits for Asian immigrant families...
November 17, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/29157322/developmental-relations-between-amygdala-volume-and-anxiety-traits-effects-of-informant-sex-and-age
#12
Katherine Rice Warnell, Meredith Pecukonis, Elizabeth Redcay
Although substantial human and animal evidence suggests a role for the amygdala in anxiety, literature linking amygdala volume to anxiety symptomatology is inconclusive, with studies finding positive, negative, and null results. Clarifying this brain-behavior relation in middle to late childhood is especially important, as this is a time both of amygdala structural maturation and the emergence of many anxiety disorders. The goal of the current study was to clarify inconsistent findings in previous literature by identifying factors moderating the relation between amygdala volume and anxiety traits in a large sample of typically developing children aged 6-13 years (N = 72)...
November 21, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29157006/chronotype-description-in-search-of-a-solid-subjective-amplitude-scale
#13
Halszka Oginska, Justyna Mojsa-Kaja, Olivier Mairesse
The term "subjective circadian amplitude" refers to the range or the distinctness of diurnal variations of arousal, that is, the awareness (or lack thereof) of difference between hyper- and hypo-activation phases, the ability to volitionally modulate one's own psychophysiological state, the strength of morning-evening preferences and flexibility of the rhythm or perceived stability of the circadian phase. The complexity of this construct is the source of difficulties in research and measurement. The psychometric features of distinctness subscales of the Chronotype Questionnaire and the Caen Chronotype Questionnaire are not satisfactory...
November 20, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29156800/comparative-molecular-analyses-of-left-sided-colon-right-sided-colon-and-rectal-cancers
#14
Mohamed E Salem, Benjamin A Weinberg, Joanne Xiu, Wafik S El-Deiry, Jimmy J Hwang, Zoran Gatalica, Philip A Philip, Anthony F Shields, Heinz-Josef Lenz, John L Marshall
Tumor sidedness has emerged as an important prognostic and predictive factor in the treatment of colorectal cancer. Recent studies demonstrate that patients with advanced right-sided colon cancers have a worse prognosis than those with left-sided colon or rectal cancers, and these patient subgroups respond differently to biological therapies. Historically, management of patients with metastatic colon and rectal cancers has been similar, and colon and rectal cancer patients have been grouped together in large clinical trials...
October 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29156291/engineering-the-next-generation-tin-containing-%C3%AE-titanium-alloys-with-high-strength-and-low-modulus-for-orthopedic-applications
#15
Sumit Bahl, Suvam Das, Satyam Suwas, Kaushik Chatterjee
Metastable β Ti alloys are the new emerging class of biomaterial for load bearing orthopedic applications. However, these alloys in the single β phase microstructure have insufficient strength for use in load bearing applications. It is imperative to strengthen these alloys by carefully designed thermo-mechanical processing routes that typically involve aging treatment. In this investigation two newly designed Sn based β Ti alloys of composition Ti-32Nb-(2, 4) Sn are evaluated. The effects of Sn content on the mechanical properties and biological performance of these alloys processed through designed thermo-mechanical processing route are investigated...
November 11, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29156247/humor-doesn-t-retire-improvisation-as-a-health-promoting-intervention-for-older-adults
#16
Lucy A Morse, Linda Xiong, Vanessa Ramirez-Zohfeld, Seltzer Anne, Becca Barish, Lee A Lindquist
As our population ages and aging in place continues to remain a priority of older adults, identifying novel ways to promote the wellbeing of older adults and reduce isolation is of the utmost importance. The Second City is a Chicago-based comedy improvisation organization that provides training in improvisation. One of their training courses, Humor Doesn't Retire, specifically teaches adults 55 and over, on improvisation. This study sought to explore the experiences of older adults enrolled in Humor Doesn't Retire, and to characterize any benefits that older adult participants perceived following participation in the comedy improvisation course...
October 28, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29155913/probing-electrochemically-induced-resistive-switching-of-tio2-using-spm-techniques
#17
Wanheng Lu, Lai-Mun Wong, Shijie Wang, Kaiyang Zeng
Resistive switching on the nanoscale is an emerging research field and Scanning Probe Microscopy (SPM) is a powerful tool for studies in this area. Under the SPM tip, the electrical field is very high due to the small tip radius on the order of tens of nanometers, and this can enable a range of ionic/electrochemical phenomena during the resistive switching of the materials under the SPM tip. Although the ionic/electrochemical phenomena have long been considered vital for the resistive switching of materials, a few pieces of experimental evidence, as well as the decoupling of the effects of the electrochemical processes at different stages, are still needed...
November 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29155331/evolution-of-vomeronasal-receptor-1-v1r-genes-in-the-common-marmoset-callithrix-jacchus
#18
Keiko Moriya-Ito, Takashi Hayakawa, Hikoyu Suzuki, Kimiko Hagino-Yamagishi, Masato Nikaido
Pheromones are crucial for eliciting innate responses and inducing social and sexual behaviors in mammals. The vomeronasal receptor 1 genes, V1Rs, encode members of a pheromone receptor family that are mainly expressed in the vomeronasal organ (VNO). The V1R family shows extraordinary variety in gene number among vertebrates owing to successive gene gains and losses during evolution. Such diversity is believed to reflect a degree of dependence on the VNO. We investigated V1R evolution in primate lineages closely related to humans because these VNOs show a trend toward degeneration...
November 16, 2017: Gene
https://www.readbyqxmd.com/read/29155095/behavioral-and-neural-mechanisms-by-which-prior-experience-impacts-subsequent-learning
#19
Ryan G Parsons
Memory is often thought about in terms of its ability to recollect and store information about the past, but its function likely rests with the fact that it permits adaptation to ongoing and future experience. Thus, the brain circuitry that encodes memory must act as if stored information is likely to be modified by subsequent experience. Considerable progress has been made in identifying the behavioral and neural mechanisms supporting the acquisition and consolidation of memories, but this knowledge comes largely from studies in laboratory animals in which the training experience is presented in isolation from prior experimentally-controlled events...
November 16, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/29154964/lipotoxicity-and-the-gut-liver-axis-in-nash-pathogenesis
#20
REVIEW
Fabio Marra, Gianluca Svegliati-Baroni
The pathogenesis of nanoalcoholic fatty liver disease is still incompletely understood, in particolar the mechanisms whereby a minority of patients develop a more severe phenotype characterized by hepatocellular damage, inflammation, and fibrosis. In this review we discuss two pivotal aspects of the pathogenesis of NASH. We first analyze the initial mechanisms responsible of hepatocellular damage and inflammation, which derive from the toxic effects of excess lipids. Accumulating data indicate that the total amount of triglycerides stored in hepatocytes is not the major determinant of lipotoxicity, and that specific lipid classes act as damaging agents on liver cells...
November 14, 2017: Journal of Hepatology
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