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https://www.readbyqxmd.com/read/29780224/correlative-study-between-c-reactive-protein-clinical-severity-and-nerve-conduction-studies-in-guillain-barr%C3%A3-syndrome
#1
Yosria A Altaweel, Sawsan Abdelaziz, Hala A Fathy, Shimaa AbdelBadea
Background: Guillain-Barre' syndrome (GBS) is a serious autoimmune disorder in which the immune system attacks healthy nerve cells of the peripheral nervous system causing polyradiculoneuropathy which leads to weakness, numbness, and tingling, and can eventually cause paralysis. Autoimmune conditions like GBS can induce a high level of inflammation resulting in an increase in the C-reactive protein( CRP) production. The aim of this study is to assess the relationship between CRP level and the clinical severity as well as the electrophysiological findings of nerve conduction studies in patients with GBS...
2018: Egypt J Neurol Psychiatr Neurosurg
https://www.readbyqxmd.com/read/29768030/evaluation-of-petrifilm-lactic-acid-bacteria-plates-for-counting-lactic-acid-bacteria-in-food
#2
Satomi Kanagawa, Chihiro Ohshima, Hajime Takahashi, Burenqiqige, Misato Kikuchi, Fumina Sato, Ayaka Nakamura, Shimaa M Mohamed, Takashi Kuda, Bon Kimura
Although lactic acid bacteria (LAB) are used widely as starter cultures in the production of fermented foods, they are also responsible for food decay and deterioration. The undesirable growth of LAB in food causes spoilage, discoloration, and slime formation. Because of these adverse effects, food companies test for the presence of LAB in production areas and processed foods and consistently monitor the behavior of these bacteria. The 3M Petrifilm LAB Count Plates have recently been launched as a time-saving and simple-to-use plate designed for detecting and quantifying LAB...
May 16, 2018: Journal of Food Protection
https://www.readbyqxmd.com/read/29762531/synthesis-spectroscopic-and-biological-studies-of-mixed-ligand-complexes-of-gemifloxacin-and-glycine-with-zn-ii-sn-ii-and-ce-iii
#3
Shimaa H Sakr, Hazem S Elshafie, Ippolito Camele, Sadeek A Sadeek
Three novel mixed ligand metal complexes have been synthesized by the reaction of Zn(II), Sn(II), and Ce(III) with gemifloxacin (GMFX) in the presence of glycine (Gly) (1:1:1 molar ratio). The coordination possibility of the two ligands toward metal ions has been proposed in the light of elemental analysis, molar conductance, spectral infrared (IR), ultraviolet-visible (UV-Vis) and proton-nuclear magnetic resonance (¹H NMR), and magnetic studies. Results suggest that GMFX and Gly interact with the metal ions as bidentate ligands...
May 15, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29759200/rapid-colorimetric-lactoferrin-based-sandwich-immunoassay-on-cotton-swabs-for-the-detection-of-foodborne-pathogenic-bacteria
#4
Saleh Alamer, Shimaa Eissa, Raja Chinnappan, Paul Herron, Mohammed Zourob
Cotton swab is the conventional swabbing tool that is usually applied for collecting pathogens from contaminated surfaces, followed by cells lysis and DNA extraction before subjecting to genetic analysis. However, such an approach is time consuming as it involves several steps and requires highly trained personnel to perform the experiment. In this study, we developed a new cotton swab-based detection system that involved integrating bacterial collection, preconcentration and detection on Q-tips. The platform is based on a sandwich assay that can detect different pathogens visually by color changes...
August 1, 2018: Talanta
https://www.readbyqxmd.com/read/29757684/an-account-of-the-real-life-hepatitis-c-management-in-a-single-specialized-viral-hepatitis-treatment-centre-in-egypt-results-of-treating-7042-patients-with-7-different-direct-acting-antiviral-regimens
#5
Mohamed El Kassas, Mohamed Alboraie, Dalia Omran, Mohamed Salaheldin, Mohamed Naguib Wifi, Mohamed ElBadry, Adel El Tahan, Sameera Ezzat, Enass Moaz, Amir M Farid, Heba Omar, Mahmoud Abouelkhair, Shimaa Afify, Kadry Elsaeed, Yehia Shazly, Wahid Doss, Gamal Esmat
BACKGROUND: A large Egyptian treatment program for HCV was launched in 2014 after the introduction of direct-acting antiviral agents (DAAs). This program depended mainly on establishing specialized independent centres for HCV treatment. These centres represent the major strengths in the Egyptian model of care, as they provide integrated care for HCV patients and have enabled Egypt to treat more than one million patients in 3 years. The New Cairo Viral Hepatitis Treatment Center (NCVHTC) is an example of these specialized centres...
May 14, 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29743497/radioprotective-effect-of-date-syrup-on-radiation-induced-damage-in-rats
#6
Shimaa M Abou-Zeid, Badr E El-Bialy, Nermeen B El-Borai, Huda O AbuBakr, Abdel Monsef A Elhadary
Ionizing radiation has cytotoxic and genotoxic effects caused mainly by the oxidative damage induced by free radical release. The need for radioprotectives is increasing to protect normal tissues during radiotherapy. In the present study, we investigated the radioprotective effect of Date syrup in rats subjected to whole body radiation at 6 Gy through biochemical, molecular and histopathological analysis. Significant elevations were recorded in the activities of serum ALT, AST, ALP and LDH and in the levels of all lipid profiles parameters, while the level of HDL-C was reduced...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29704207/effects-of-selenium-and-chromium-enriched-diets-on-growth-performance-lipid-profile-and-mineral-concentration-in-different-tissues-of-growing-rabbits
#7
Shimaa A Amer, Anaam E Omar, Mohamed E Abd El-Hack
The aim of this study was to investigate the effect of dietary supplementation with different sources of selenium and/or organic chromium on the growth performance, digestibility, lipid profile, and mineral content of hair, liver, and fore and hind limb of growing rabbits. A total of 150 weanling New Zealand White (NZW) male rabbits were randomly allotted to six dietary treatment groups: (1) basal diet (control group), (2) basal diet + 0.6 mg sodium selenite/kg diet, (3) basal diet + 0.6 mg selenium yeast/kg diet, (4) basal diet + 0...
April 27, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29693337/impact-of-mesenchymal-stem-cells-and-vitamin-d-on-transforming-growth-factor-beta-signaling-pathway-in-hepatocellular-carcinoma-in-rats
#8
Shimaa Saad El-Din, Hanan Fouad, Laila Ahmed Rashed, Soheir Mahfouz, Rania Elsayed Hussein
Background: Transforming growth factor-beta (TGF-β) signaling is recognized as being critical for carcinogenesis. Vitamin D has proved to exert numerous tumor suppressive effects. Effects of bone marrow derived mesenchymal stem cells (BM-MSCs) on tumor progression are still controversial. The present study was conducted to evaluate the effects of BM-MSCs and vitamin D on TGF-β signaling in an experimental hepatocellular carcinoma (HCC) model in rats. Materials and Methods: The study was conducted on fifty female white albino rats divided equally into 5 groups: controls, HCC induced by diethyl-nitrosamine (DENA) and carbon tetrachloride (CCl4), HCC plus MSCs, HCC plus vitamin D and HCC plus both MSCs and vitamin D...
April 25, 2018: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29675559/truncated-aptamers-for-total-and-glycated-hemoglobin-and-their-integration-into-a-graphene-oxide-based-fluorometric-method-for-high-throughput-screening-for-diabetes
#9
Abrar Yousef Almusharraf, Shimaa Eissa, Mohammed Zourob
The authors describe the identification of an effective binding region of aptamers against glycated (HbA1c) and total haemoglobin (tHb) by using a fluorometric assay. Truncation of the originally selected aptamers from 60 to 46 and 34 nucleotides for HbA1c and tHb, respectively, enhances the affinity for their targets. Moreover, shortening the aptamer sequences leads to a better conformational change after target binding which enabled the integration of the aptamers in a graphene oxide (GO)-based fluorometric assay...
April 19, 2018: Mikrochimica Acta
https://www.readbyqxmd.com/read/29657408/interspecies-comparison-of-probiotics-isolated-from-different-animals
#10
Amr M Abdou, Riham H Hedia, Shimaa T Omara, Mohamed Abd El-Fatah Mahmoud, Mai M Kandil, M A Bakry
Aim: The aim of the current study was to isolate and identify naturally occurring probiotic Lactobacillus species in different animals with the different environmental background including fish, and farm animals to investigate interspecies differences in probiotics on the species level. Materials and Methods: A total of 44 fecal and milk samples were collected under aseptic conditions from cattle, buffalo, camel, sheep, goats, and fish. The samples were cultured, and the isolated strains were confirmed biochemically and molecularly using 16S rRNA multiplex polymerase chain reaction (PCR) analysis following DNA extraction from the bacterial isolates...
February 2018: Veterinary World
https://www.readbyqxmd.com/read/29622989/echocardiographic-predictors-of-atrial-fibrillation-after-mitral-valve-replacement
#11
REVIEW
Al-Shimaa Mohamed Sabry, Heba Abd El-Kader Mansour, Tarek Helmy Abo El-Azm, Shimaa Ahmed Mostafa, Basant Samy Zahid
Objectives: Detection of the echocardiographic predictors of post-operative atrial fibrillation in patients with rheumatic mitral valve disease undergoing mitral valve replacement. Methods: The study included 50 patients with rheumatic mitral valve disease undergoing mitral valve replacement. Preoperative assessment included standard two-dimensional echocardiography to assess LA diameter, volume, and emptying fraction, LV volume and ejection fraction. TDI derived velocity, strain of the left atrium and speckle tracking to assess left ventricular function then postoperative follow up for 1 month for occurrence of atrial fibrillation...
December 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29594804/a-rapid-colorimetric-immunoassay-for-the-detection-of-pathogenic-bacteria-on-poultry-processing-plants-using-cotton-swabs-and-nanobeads
#12
Saleh Alamer, Shimaa Eissa, Raja Chinnappan, Mohammed Zourob
The work describes a simple cotton swab-based colorimetric immunoassay as a rapid screening tool for pathogenic bacteria on poultry processing plants. This immunosensing platform can be used for the detection of pathogens present on surfaces such as glass, stainless steel and chicken meat. Unlike the reported assays, here, cotton swab plays dual function: as a sample collector from the solid surfaces and as detection platform. The immunoassay was tested for the detection of 4 different bacteria; Salmonella typhimurium, Salmonella enteritidis, Staphylococcus aureus and Campylobacter jejuni...
February 10, 2018: Mikrochimica Acta
https://www.readbyqxmd.com/read/29594712/fluorometric-graphene-oxide-based-detection-of-salmonella-enteritis-using-a-truncated-dna-aptamer
#13
Raja Chinnappan, Saleh AlAmer, Shimaa Eissa, Anas Abdel Rahamn, Khalid M Abu Salah, Mohammed Zourob
The work describes a fluorescence-based study for mapping the highest affinity truncated aptamer from the full length sequence and its integration in a graphene oxide platform for the detection of Salmonella enteriditis. To identify the best truncated sequence, molecular beacons and a displacement assay design are applied. In the fluorescence displacement assay, the truncated aptamer was hybridized with fluorescein and quencher-labeled complementary sequences to form a fluorescence/quencher pair. In the presence of S...
December 18, 2017: Mikrochimica Acta
https://www.readbyqxmd.com/read/29568203/role-of-relevant-immune-modulators-and-cytokines-in-hepatocellular-carcinoma-and-premalignant-hepatic-lesions
#14
Abdel-Rahman N Zekri, Somaya El Deeb, Abeer A Bahnassy, Abeer M Badr, Mona S Abdellateif, Gamal Esmat, Hosny Salama, Marwa Mohanad, Ahmed Esam El-Dien, Shimaa Rabah, Assmaa Abd Elkader
AIM: To assess the levels of different immune modulators in patients with hepatocellular carcinoma (HCC), in relation to other hepatic diseases. METHODS: Eighty-eight patients were included in the current study and represented patients with HCC (20), liver cirrhosis (28) and chronic hepatitis (CH; 25), and normal controls (NC; 15). Peripheral blood was isolated for immunophenotyping of active myeloid dendritic cells (mDCs; CD1c and CD40), mature inactive myeloid cells (CD1c and HLA), active plasmacytoid cells (pDCs; CD303 and CD40), mature inactive pDCs (CD30 and HLA), active natural killer (NK) cells (CD56 and CD161), active NK cells (CD56 and CD314) and inactive NK cells (CD56 and CD158) was done by flow cytometry...
March 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29530503/vitamin-d-deficiency-and-vitamin-d-receptor-variants-in-mothers-and-their-neonates-are-risk-factors-for-neonatal-sepsis
#15
Safaa I Tayel, Shimaa E Soliman, Hanan M Elsayed
BACKGROUND AND AIM: Increasing prevalence of neonatal sepsis in recent years catch attention to early prevention and management. Vitamin D receptor (VDR) polymorphism can modulate VDR expression level that greatly influences immunity and susceptibility to microbial infections. We aimed to investigate the association of VDR polymorphism at FokI, rs2228570 T/C, and TaqI, rs731236 C/T gene with serum 25-hydroxyvitamin D level and risk of neonatal sepsis. METHODS: This work carried on 160 subjects classified into 80 cases (40 mothers and their 40 septic neonates) and 80 healthy controls (40 volunteer mothers and their 40 healthy neonates)...
June 2018: Steroids
https://www.readbyqxmd.com/read/29528112/n-methylation-in-amino-acids-and-peptides-scope-and-limitations
#16
REVIEW
Anamika Sharma, Ashish Kumar, Shimaa A H Abdel Monaim, Yahya E Jad, Ayman El-Faham, Beatriz G de la Torre, Fernando Albericio
Active pharmaceutical ingredients (APIs) can be divided into two types, namely chemical and biological entities. Traditionally, the former has been associated with the so-called small molecules. The revival of peptides in pharmaceutical industry results from their importance in many biological roles. However, low metabolic stability and the lack of oral availability of most peptides is the main drawback for peptide to fulfill that paradigmatic situation. In this regard, efforts are being channeled into addressing this issue by introducing restrictions into the flexible peptide backbone, mainly through N-methyl amino acids (NMAAs) or development of small cyclic peptides...
March 12, 2018: Biopolymers
https://www.readbyqxmd.com/read/29524879/chemosensitizing-effect-of-alpinia-officinarum-rhizome-extract-in-cisplatin-treated-rats-with-hepatocellular-carcinoma
#17
Shimaa A Abass, Nabil M Abdel-Hamid, Tarek K Abouzed, Mamdouh Mohammad El-Shishtawy
This study was conducted to estimate the preventing and sensitizing efficiency of Alpinia officinarum rhizome extract (AORE) in an experimental model of hepatocellular carcinoma (HCC) +/- cisplatin. HCC was induced by a single intraperitoneal (i.p) dose of diethylnitrosamine (DENA, 200mg/kg). After 14 days, phenobarbitone (PB, 0.05%) was added to drinking water for 14 weeks to promote hepatocarcinogenesis. Cisplatin (CP) was given in a dose of 1.5 mg/kg (i.p), twice a week, alone or with AORE (400 mg/kg daily, orally) for 21 days...
May 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29498455/ethnicity-influences-breast-cancer-stem-cells-drug-resistance
#18
Mohamed Kamal, Ebtesam H O Nafie, Shimaa Elsers, Salma Alanwar, Rawayeh Ibrahim, Fatma Farag, Mohamed Mlees, Bruno M Simões, Kath Spence, Angélica Santiago-Gómez, Mohamed L Salem, Robert B Clarke
No abstract text is available yet for this article.
March 2, 2018: Breast Journal
https://www.readbyqxmd.com/read/29498183/il1a-889-gene-polymorphism-is-associated-with-the-effect-of-diet-as-a-risk-factor-in-acne-vulgaris
#19
Adel A Ibrahim, Rehab M Salem, Ola S El-Shimi, Shaymaa M A Baghdady, Shimaa Hussein
BACKGROUND: Despite the several studies suggesting the genetic basis of acne vulgaris, the exact genetic architecture of this very common condition is not yet clear. AIM OF THE WORK: This study aimed to investigate the association between IL-1A (-889) gene polymorphism and acne vulgaris in a sample of patients. SUBJECTS AND METHOD: Blood samples from 100 patients with acne vulgaris and 100 healthy age, sex, and BMI matched controls were obtained...
March 1, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29493404/mycobacterium-marinum-infection-in-fish-and-man-epidemiology-pathophysiology-and-management-a-review
#20
Emad Hashish, Abdallah Merwad, Shimaa Elgaml, Ali Amer, Huda Kamal, Ahmed Elsadek, Ayman Marei, Mahmoud Sitohy
Mycobacterium marinum is an opportunistic pathogen inducing infection in fresh and marine water fish. This pathogen causes necrotizing granuloma like tuberculosis, morbidity and mortality in fish. The cell wall-associated lipid phthiocerol dimycocerosates, phenolic glycolipids and ESAT-6 secretion system 1 (ESX-1) are the conserved virulence determinant of the organism. Human infections with Mycobacterium marinum hypothetically are classified into four clinical categories (type I-type IV) and have been associated with the exposure of damaged skin to polluted water from fish pools or contacting objects contaminated with infected fish...
December 2018: Veterinary Quarterly
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