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Surgery pathology

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https://www.readbyqxmd.com/read/28214211/expression-of-bmp-4-in-papillary-thyroid-carcinoma-and-its-correlation-with-tumor-invasion-and-progression
#1
Xiaomei Meng, Peng Zhu, Ning Li, Jinchen Hu, Shaoguang Wang, Shuguang Pang, Jiahui Wang
Bone morphogenetic protein 4 (BMP-4) is a member of the BMP protein family. BMP-4 was reported to induce epithelial-mesenchymal transition (EMT) and promote tumor cell immigration and invasion. This study aimed to investigate the expression of BMP-4 in papillary thyroid carcinoma (PTC) and its correlation with the patients' clinicophathological features and with tumor invasion and metastasis. Surgically resected PTC specimens from 82 patients admitted to the Department of Thyroid Surgery of Yantai Yuhuangding Hospital between Feb 1st and May 31st, 2016 were collected...
January 17, 2017: Pathology, Research and Practice
https://www.readbyqxmd.com/read/28213624/oligometastatic-colorectal-cancer-is-single-site-bony-colorectal-metastasis-a-treatable-condition
#2
Noel Cassar, Adrian Ben Cresswell, Brendan Moran
INTRODUCTION: A potentially resectable bony metastasis in the context of oligometastatic colorectal cancer is uncommon. Bony metastases are usually considered a late event with poor prognosis and generally associated with liver and/or lung metastases. INDEX CASE: A previously healthy 33-year-old gentleman, with no family history of colorectal cancer, presented with rectal bleeding and at colonoscopy had a biopsy-proven adenocarcinoma of the rectum, 7 cm from the anal verge...
February 17, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28213198/a-rare-presentation-of-an-enterogenous-cyst-as-an-intra-axial-pontine-lesion
#3
Tengfei Li, Xia Wu, Yuekang Zhang
A 56-year-old man was admitted to our hospital with intermittent right facial numbness for one year and walking instability for six months. Magnetic resonance imaging revealed an ovoid and well-demarcated intra-axial pontine lesion. Cyst fenestration and biopsy were carried out and the diagnosis of enterogenous cyst was made by MRI and pathologic findings. Preoperative symptoms resolved completely three months after surgery and no evidence of recurrence was found during 3 years of follow-up. Although total resection of enterogenous cysts is recommended, cyst fenestration may be useful if the cyst is adherent to vital neurovascular structures...
February 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28213166/influence-of-clamping-stress-and-duration-on-the-trauma-of-liver-tissue-during-surgery-operation
#4
Jin Wang, Qing-Yuan Yu, Wei Li, Bing-Rui Wang, Zhong-Rong Zhou
BACKGROUND: Tissue grasping damage often occurs in minimally invasive surgery, which would increase the postoperative recovery time and the risk of surgical complications. The purpose of this study was to evaluate the relationship between liver tissue trauma and compression stress magnitude and duration during tissue clamping operation. METHODS: The clamping experiments of liver tissues in vivo were conducted by using a universal soft tissue mechanical testing machine under different clamping stress magnitudes and durations...
February 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28213006/a-prospective-multi-institutional-phase-ii-study-of-induction-chemoradiotherapy-followed-by-surgery-in-patients-with-non-small-cell-lung-cancer-involving-the-chest-wall-cjlsg0801
#5
Koji Kawaguchi, Kohei Yokoi, Hiroshi Niwa, Yasuhisa Ohde, Shoichi Mori, Sakae Okumura, Satoshi Shiono, Hiroyuki Ito, Motoki Yano, Kikuo Shigemitsu, Yoshinori Hiramatsu, Jiro Okami, Hideo Saka
OBJECTIVES: The standard therapy for patients with T3N0-1M0 non-small cell lung cancer (NSCLC) involving the chest wall is considered surgical resection and adjuvant therapy. However, the compliance of adjuvant therapy is relatively low, and the prognosis for those patients has been unsatisfactory. Therefore, we conducted a phase II study of induction chemoradiotherapy followed by surgery with the aim of improving the survival. PATIENTS AND METHODS: This treatment strategy consisted of induction chemotherapy (two cycles of cisplatin at 80mg/m(2) on Day 1 and vinorelbine at 20mg/m(2) on Days 1 and 8) concurrent with radiotherapy (40Gy in 20 fractions) followed by surgery...
February 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28212594/percutaneous-full-endoscopic-treatment-of-bertolotti-syndrome-a-report-of-three-cases-with-technical-note
#6
Byapak Paudel, Hyeun-Sung Kim, Jee Soo Jang, Jeong Hoon Choi, Sung Kyun Chung, Jung Sup Lee, Jeong Hoon Kim, Seong Hoon Oh, Il Tae Jang
Background Bertolotti syndrome is characterized by an abnormal enlargement of the transverse process of the most caudal lumbar vertebra. Most of the time it is asymptomatic, but when it is symptomatic it is associated with low back pain, radiating leg pain, or both. There is no consensus regarding management of this pathology. Open to minimal invasive tubular resection techniques are described in the literature, but a full endoscopic resection technique has not yet been described. Endoscopic technique is a less invasive target-oriented iliolumbar ligament preserving technique...
February 17, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28212354/the-effect-of-dexmedetomidine-on-oxidative-stress-response-following-cerebral-ischemia-reperfusion-in-rats-and-the-expression-of-intracellular-adhesion-molecule-1-icam-1-and-s100b
#7
Yanwen Li, Shikun Liu
BACKGROUND Ischemia-reperfusion injury of whole brain involves a complicated pathophysiology mechanism. Dexmedetomidine (Dex) has been shown to have neuro protective functions. This study observed the effect of Dex on serum S100B and cerebral intracellular adhesion molecule-1 (ICAM-1) in a rat model of cerebral ischemia-reperfusion. MATERIAL AND METHODS Healthy Sprague Dawley (SD) rats (males, 7 weeks old) were randomly divided into sham, model, and Dex groups (n=20 each). A cerebral ischemia-reperfusion model was prepared by clipping of the bilateral common carotid artery combined with hypotension...
February 17, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28212263/shoulder-synovial-fluid-lipoprotein-levels-and-their-relationship-to-the-rotator-cuff
#8
Daniel E Davis, Alexa Narzikul, Daniel Sholder, Mark Lazarus, Surena Namdari, Joseph Abboud
INTRODUCTION: Rotator cuff pathology has been proposed to occur through intrinsic and extrinsic mechanisms. Hyperlipidemia has been proposed as a mechanism of intrinsic rotator cuff pathology. This prospective observational study evaluates serum and synovial lipid profiles in patients with and without rotator cuff tears to further define the relationship of cholesterol and rotator cuff pathology. METHODS: Patients were prospectively enrolled with intact rotator cuff (37 patients) and rotator cuff tear requiring a repair (40 patients) groups...
March 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28212258/factors-influencing-difficulty-of-laparoscopic-abdominoperineal-resection-for-ultra-low-rectal-cancer
#9
Qiken Li, Dechuan Li, Lai Jiang, Pengnian Qiu, Zhixuan Fu, Lilong Tang, Weiping Chen
PURPOSE: Our current study was conducted to identify patients' anatomic, pathologic, and clinical factors to predict difficulty of performing laparoscopic abdominoperineal resection for ultra-low rectal cancer. MATERIALS AND METHODS: Records of 117 consecutive patients with rectal cancer 2 to 5 cm from the anal verge were retrospectively reviewed. Using univariate and multivariate linear or logistic regression models, standardized operative time and blood loss, as well as postoperative morbidity were utilized as endpoints to screen patients' multiple variables to predict operative difficulty...
February 16, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28212172/cognitive-decline-associated-with-anesthesia-and-surgery-in-the-elderly-does-this-contribute-to-dementia-prevalence
#10
Lisbeth Evered, David A Scott, Brendan Silbert
PURPOSE OF REVIEW: To provide an update on the current state of research investigating the effects of anesthesia and surgery on cognition in the elderly, including consideration of overlap with cognitive disorders in the community. RECENT FINDINGS: The studies reviewed here identify detrimental effects of anesthesia and surgery on cognition in a proportion of elderly individuals. Animal models demonstrate an association between anesthetic agents and Alzheimer's disease pathology...
February 15, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28212125/functional-endoscopic-surgery-after-facial-trauma
#11
Marzia Petrocelli, Carolina Sbordone, Giovanni Salzano, Francesco Maria Cassandro, Giuseppe Chiarella, Alfonso Scarpa, Antonio Romano, Giorgio Iaconetta, Luigi Califano, Ettore Cassandro
The present study describes 3 patients of previous facial trauma who have subsequently been treated with functional endoscopic sinus surgery. The authors want pay attention on the possible correlation between facial trauma and sinusitis. Such fractures can be the cause of onset of paranasal sinusitis or of worsening of a previous sinusitis. The correlation between these 2 pathologies could be due to the fact that facial fractures concern the anatomic structures of paranasal sinuses. The damage to these structures during the facial trauma and tissue regeneration after injury or surgical treatment subverts the anatomy and function of the sinuses in a basically compromised situation...
February 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28211807/two-dimensional-shear-wave-elastography-of-breast-lesions-comparison-of-two-different-systems
#12
Wei-Wei Ren, Xiao-Long Li, Ya-Ping He, Dan-Dan Li, Dan Wang, Chong-Ke Zhao, Xiao-Wan Bo, Bo-Ji Liu, Wen-Wen Yue, Hui-Xiong Xu
OBJECTIVE: To evaluate the diagnostic performance of two different shear wave elastography (SWE) techniques in distinguishing malignant breast lesions from benign ones. MATERIALS AND METHODS: From March 2016 to May 2016, a total of 153 breast lesions (mean diameter, 16.8 mm±10.5; range 4.1-90.0 mm) in 153 patients (mean age, 46.4 years±15.1; age range 20-86 years) were separately performed by two different SWE techniques (i.e. T-SWE, Aplio500, Toshiba Medical System, Tochigi, Japan; and S-SWE, the Aixplorer US system, SuperSonic Imagine, Provence, France)...
February 17, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28211283/gallstone-ileus-presenting-as-obstructive-gangrenous-appendicitis
#13
José Cruz-Santiago, Giuseppe Briceño-Sáenz, Javier García-Álvarez, José Luis Beristain-Hernández
We present the very unusual case of a 38-year-old woman with acute appendicitis and intestinal obstruction. During surgery, a 2.5 cm gallstone impacted at the base of the cecal appendix was found as the cause of a gangrenous appendicitis and obstruction; a choledochal-duodenal fistula was found during the same surgery with no gallstones remaining in the gallbladder or elsewhere. The case was managed by appendectomy with retrieval of the gallstones and no other procedure was performed for the gallbladder or the fistula, since no other gallstone was found on examination...
February 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28210944/postoperative-imaging-in-arthroscopic-hip-surgery
#14
REVIEW
F Di Pietto, V Chianca, R de Ritis, E Cesarano, A Reginelli, A Barile, M Zappia, L Ginolfi
Arthroscopic surgery of the hip, compared to that of the knee or the shoulder, has only recently been developed in any significant way. Current indications for arthroscopic surgery of the hip include: diagnosis and treatment of lesions symptomatic of the acetabular labrum, femoroacetabular impingement (FAI), chondral lesions, joint infections, lesions of the teres ligament, impingement of the psoas tendon, pathology of the peritrochanteric space, external snapping hip (coxa saltans), and traumatic and atraumatic instability...
February 16, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28210937/imp3-expression-in-small-intestine-neuroendocrine-neoplasms-a-new-predictor-of-recurrence
#15
Sara Massironi, Alessandro Del Gobbo, Federica Cavalcoli, Stefano Fiori, Dario Conte, Alessio Pellegrinelli, Massimo Milione, Stefano Ferrero
PURPOSE: Small-intestine neuroendocrine neoplasms are heterogeneous neoplasms arising from endocrine cells of the intestinal mucosa. Ki-67 is the main determinant of prognosis in neuroendocrine neoplasms. However, the search for new prognostic makers represents a key point with regard to small-intestine neuroendocrine neoplasms. The oncofetal protein IMP3 plays a role in cell growth and its expression has a prognostic value in lung neoplasms. METHODS: From January 1998 to August 2015, all the consecutive small-intestine neuroendocrine neoplasms patients suitable for surgery were included: 51 patients (32 males, median age 68 years) had small-intestine neuroendocrine neoplasms classified according to the WHO 2010 classification...
February 17, 2017: Endocrine
https://www.readbyqxmd.com/read/28210834/conservative-treatment-in-uncomplicated-acute-appendicitis-reassessment-of-practice-safety
#16
Zvi Steiner, Genady Buklan, Rodica Stackievicz, Michael Gutermacher, Ita Litmanovitz, Guy Golani, Shmuel Arnon
: The success rate of conservative treatment for children with uncomplicated appendicitis was prospectively evaluated among 197 children. All who received intravenous antibiotics for 3-5 days, and if symptoms resolved, were discharged home on oral antibiotics for 5 days. Failure rate, symptoms, laboratory signs, and sonographic findings were evaluated for prognostic markers of treatment failure. Children were followed for 18 months. The success rate of conservative treatment was 87%, with shorter hospital stays compared to children who eventually needed surgery (72 [60-84] vs...
February 16, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28210788/surgical-management-of-degenerative-meniscus-lesions-the-2016-esska-meniscus-consensus
#17
Ph Beaufils, R Becker, S Kopf, M Englund, R Verdonk, M Ollivier, R Seil
PURPOSE: A degenerative meniscus lesion is a slowly developing process typically involving a horizontal cleavage in a middle-aged or older person. When the knee is symptomatic, arthroscopic partial meniscectomy has been practised for a long time with many case series reporting improved patient outcomes. Since 2002, several randomised clinical trials demonstrated no additional benefit of arthroscopic partial meniscectomy compared to non-operative treatment, sham surgery or sham arthroscopic partial meniscectomy...
February 16, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28210708/evaluation-of-aga-and-fukuoka-guidelines-for-eus-and-surgical-resection-of-incidental-pancreatic-cysts
#18
Alexander Lee, Vivek Kadiyala, Linda S Lee
Objectives Management of asymptomatic pancreatic cysts is challenging. Guidelines by the American Gastroenterological Association (AGA) and International Association of Pancreatology (Fukuoka) seek to identify high-risk patients. We assessed performance of these guidelines in selecting patients for endoscopic ultrasound (EUS) and/or surgery. Methods PART I - We retrospectively studied 143 asymptomatic cysts with magnetic resonance imaging (MRI) followed by EUS. Appropriate selection for EUS was defined as: malignant cytology or surgical pathology, or development of concerning features on MRI as defined by the guidelines...
February 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28210705/gastric-esd-may-be-useful-as-accurate-staging-and-decision-of-future-therapeutic-strategy
#19
Ai Fujimoto, Osamu Goto, Toshihiro Nishizawa, Yasutoshi Ochiai, Joichiro Horii, Tadateru Maehata, Teppei Akimoto, Satoshi Kinoshita, Seiji Sagara, Motoki Sasaki, Toshio Uraoka, Naohisa Yahagi
Background and study aims We sometimes perform gastric endoscopic submucosal dissection (ESD) for total pathologic diagnosis when preoperative diagnosis is difficult. In the present study we analyzed the treatment outcomes and adverse events of diagnostic ESD for early gastric cancer (EGC). Patients and methods We conducted a retrospective analysis of 18 consecutive cases of EGC in 18 patients with a suspected out-of-indication diagnosis who underwent diagnostic ESD, between June 2010 and November 2014...
February 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28210549/evaluation-of-discrepancies-in-weights-of-fresh-and-fixed-specimens-in-breast-surgery-a-retrospective-cohort-study
#20
Dinesh Thekkinkattil
BACKGROUND: Handling of breast specimen is not well monitored and there is limited data on the impact of fixative solutions on specimen weights. Weight of resected breast tissue acts as a guide for future reconstructive and symmetrisation procedures. The aim is to quantitatively evaluate the discrepancies in weight of fresh breast specimen and the weight of specimen after being kept in a fixative solution for a variable length of time. METHODS: Single centre retrospective cohort study including patients undergone breast surgery for both diagnostic and therapeutic purposes between January of 2013 and June 2015...
February 2017: Gland Surgery
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