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https://www.readbyqxmd.com/read/29140147/sprint-running-performance-and-technique-changes-in-athletes-during-periodized-training-an-elite-training-group-case-study
#1
Ian N Bezodis, David G Kerwin, Stephen-Mark Cooper, Aki I T Salo
PURPOSE: To understand how training periodization influences sprint performance and key step characteristics over an extended training period in an elite sprint training group. METHODS: Four sprinters were studied during five months of training. Step velocities, step lengths and step frequencies were measured from video of the maximum velocity phase of training sprints. Bootstrapped mean values were calculated for each athlete for each session and 139 within-athlete, between-session comparisons were made with a repeated measures ANOVA...
November 15, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29106864/six-month-old-infants-with-deformational-plagiocephaly-do-not-differ-from-unaffected-infants-with-respect-to-vocal-control
#2
Kathleen Wermke, Christian Linz, Annette Hasenberg, Felix Kunz, Philipp Meyer-Marcotty, Tilmann Schweitzer
OBJECTIVES: The recommendation of a supine sleeping position led to a significant reduction of SIDS, but increased positional skull deformities (DP). Here, a quantitative analysis of babbling aims to complement previous studies of language-relevant competence based on items of the Bayley-scales that suggested the presence of developmental language delays in DP infants. Measures of fundamental frequency variability as proxies for vocal control are well suited for testing this assumption, since the laryngeal neuro-muscular system matures early and is coupled with brain function while working rapidly in coordinating the structures and mechanisms involved in infant sound production...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29074396/translocation-and-dissemination-of-botulinum-neurotoxin-from-the-intestinal-tract
#3
Yukako Fujinaga, Michel R Popoff
Botulinum neurotoxins (BoNTs) are potent toxins which induce flaccid paralysis by inhibiting the release of acetylcholine at the neuromuscular junctions. They associate with non-toxic proteins (ANTPs or NAPs) to form complexes of various sizes which are resistant to acidic pH and protease degradation. BoNT trafficking from the digestive tract to the target neurons is still a matter of debate. BoNTs use different strategies to pass through the intestinal barrier including passage of BoNT complexes containing hemagglutinins (HAs) via M cells, HA-dependent perturbation of E-cadherin intercellular junctions between enterocytes and paracellular passage of BoNT complexes, and transcytosis of BoNT free of NAPs through certain intestinal epithelial cells...
October 23, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28981152/low-conversion-rate-of-ocular-to-generalized-myasthenia-gravis-in-singapore
#4
Kelvin Y Teo, Sharon L Tow, Benjamin Haaland, Tushar D Gosavi, Loo Jing-Liang, L O Yew Long, Dan Milea
INTRODUCTION: Ocular myasthenia gravis (OMG) is a common condition of the neuromuscular junction that may convert to generalized myasthenia gravis (GMG). Our aim in this study was to determine the conversion rate and predictive factors for generalization in OMG, in an Asian population. METHODS: The investigation consisted of a retrospective study of OMG patients with a minimum 2 years of follow-up. RESULTS: Among 191 patients with OMG, 155 had the minimum 2-year follow-up...
October 5, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28929907/management-of-obesity-after-spinal-cord-injury-a-systematic-review
#5
M H Shojaei, S M Alaviniaa, B C Craven
CONTEXT: Individuals with chronic spinal cord injury (SCI) are susceptible to central and visceral obesity and it's metabolic consequences; consensus based guidelines for obesity management after SCI have not yet been stablished. OBJECTIVES: To identify and compare effective means of obesity management among SCI individuals. METHODS: This systematic review included English and non-English articles, published prior to April 2017 found in the PubMed/Medline, Embase, CINAHL Psychinfo and Cochrane databases...
September 20, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28808834/biochemical-and-behavioral-phenotype-of-agat-and-gamt-deficient-mice-following-long-term-creatine-monohydrate-supplementation
#6
Furhan Iqbal, Herald Hoeger, Gurt Lubec, Olaf Bodamer
The creatine/phosphocreatine system is essential for cellular phosphate coupled energy storage and production. We investigated the utility of creatine monohydrate supplementation in two different creatine deficient knockout mouse models. Following weaning, female Arginine: Glycine Amidinotransferase (AGAT) and Guanidinoacetate: methyltransferase (GAMT) knockouts and wild type mice were studied based on their genotypes and dietary supplementation (creatine free or 2% creatine monohydrate supplemented diet) for 10 weeks, using a series of behavioral tests and biochemical analyzes...
December 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28748108/readyspeech-for-people-with-dysarthria-after-stroke-protocol-for-a-feasibility-randomised-controlled-trial
#7
Claire Mitchell, Audrey Bowen, Sarah Tyson, Paul Conroy
BACKGROUND: Dysarthria, a disordered speech production resulting from neuro-muscular impairment, is a common symptom after stroke. It causes significant problems for patients' speech intelligibility, communication, psychological well-being, social engagement and stroke recovery. Rehabilitation for dysarthria is variable in quality, intensity and duration, which may be, in part, due to the lack of good quality evidence. An online therapy programme, ReaDySpeech, has the potential to improve quality, intensity and duration of speech rehabilitation and was considered in a proof-of-concept study to be acceptable to speech and language therapists and patients which warranted further evaluation...
2018: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28709849/effects-of-huperzin-a-on-the-beta-amyloid-accumulation-in-the-brain-and-skeletal-muscle-cells-of-a-rat-model-for-alzheimer-s-disease
#8
Cagatay Han Turkseven, Belgin Buyukakilli, Ebru Balli, Derya Yetkin, Mehmet Emin Erdal, Senay Gorucu Yilmaz, Leyla Sahin
AIMS: Alzheimer's Disease (AD) is characterized by a loss of cognitive function and also the accumulation of β-amyloid peptide (βAP) in the brain parenchyma, which plays an important role in this disease. However, it is often also associated with the non-cognitive symptoms such as loss of muscle function (Inclusion-Body Myositis-IBM). MAIN METHODS: Sprague-Dawley rats (13 weeks-n=68) were randomly assigned into five groups: Group C: Control; Group D: d-galactose; Group O+D: Bilateral oophorectomy+d-galactose; Group O: Bilateral oophorectomy; Group O+D+H: Bilateral oophorectomy+d-galactose+Hup-A...
September 1, 2017: Life Sciences
https://www.readbyqxmd.com/read/28702442/kinematics-and-neuromuscular-recruitment-during-vertical-treadmill-exercise
#9
Alastair R Jordan, Andrew Barnes, David Claxton, Alison Purvis, Mary Fysh
The vertical treadmill (VertiRun) is an unresearched, partial weight-bearing exercise mode for lower limb rehabilitation. The user undertakes a "running-like" action whilst body weight is supported by a bench and the limb is drawn downwards against overhanging resistance cables on a vertically hung nonmotorised treadmill. This study sought to describe the kinematics and neuromuscular recruitment during VertiRun exercise in the supine, 40°, and 70° postures. Twenty-one healthy male participants (age, 25±7 years; stature, 1...
June 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28658860/muscle-activation-profiles-and-co-activation-of-quadriceps-and-hamstring-muscles-around-knee-joint-in-indian-primary-osteoarthritis-knee-patients
#10
Sanjeev Kumar Sharma, Shiv Lal Yadav, U Singh, Sanjay Wadhwa
INTRODUCTION: Osteoarthritis (OA) of knee is a common joint disease. It is associated with reduced knee joint stability due to impaired quadriceps strength, pain, and an altered joint structure. There is altered muscle activation in knee OA patients, which interferes with normal load distribution around the knee and facilitates disease progression. AIM: Our primary aim was to determine activation patterns of the muscles i.e., quadriceps and hamstrings in knee OA patients during walking...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28642711/weekly-time-course-of-neuro-muscular-adaptation-to-intensive-strength-training
#11
Niklas Brown, Dieter Bubeck, Daniel F B Haeufle, Johannes Weickenmeier, Ellen Kuhl, Wilfried Alt, Syn Schmitt
Detailed description of the time course of muscular adaptation is rarely found in literature. Thus, models of muscular adaptation are difficult to validate since no detailed data of adaptation are available. In this article, as an initial step toward a detailed description and analysis of muscular adaptation, we provide a case report of 8 weeks of intense strength training with two active, male participants. Muscular adaptations were analyzed on a morphological level with MRI scans of the right quadriceps muscle and the calculation of muscle volume, on a voluntary strength level by isometric voluntary contractions with doublet stimulation (interpolated twitch technique) and on a non-voluntary level by resting twitch torques...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28631679/-the-comparative-assessment-of-the-vocal-function-in-the-professional-voice-users-and-non-occupational-voice-users-in-the-late-adulthood
#12
O G Pavlikhin, S G Romanenko, D I Krasnikova, E V Lesogorova, V S Yakovlev
The objective of the present study was to evaluate the clinical and functional condition of the voice apparatus in the elderly patients and to elaborate recommendations for the prevention of disturbances of the vocal function in the professional voice users. This comprehensive study involved 95 patients including the active professional voice users (n=48) and 45 non-occupational voice users at the age from 61 to 82 years with the employment history varying from 32 to 51 years. The study was designed to obtain the voice characteristics by means of the subjective auditory assessment, microlaryngoscopy, video laryngostroboscopy, determination of maximum phonation time (MPT), and computer-assisted acoustic analysis of the voice with the use of the MDVP Kay Pentaxy system...
2017: Vestnik Otorinolaringologii
https://www.readbyqxmd.com/read/28591954/-the-effect-of-emulsified-sevofluran-on-muscular-relaxation-through-selective-blockage-of-peripheral-nerves
#13
Ling Ye, Xin-Xin Sun, Tao Zhu, Ping-Liang Yang
OBJECTIVES: To identify the site that emulsified sevoflurane influences in the nerve system. METHODS: Thirty-six healthy New Zealand rabbits were randomly and equally divided into low concentration emulsified sevoflurane group [4 mL/(kg·h)], medium concentration [6 mL/(kg·h)]group, high concentration group[10 mL/(kg·h)]and intralipid control group. Emulsified sevoflurane was infused through arterial to selectively block peripheral nerves, neuro-muscular junctions and muscle fibers...
July 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28582628/energetic-demand-and-physical-conditioning-of-table-tennis-players-a-study-review
#14
Alessandro Moura Zagatto, Miran Kondric, Beat Knechtle, Pantelis Theo Nikolaidis, Billy Sperlich
Table tennis is a racket sport characterised by an intermittent movement profile, including short rallies interspersed with short breaks. In contrast to other racket sports, information is lacking regarding the: (i) physiological responses during table tennis matches and training; and (ii) practical recommendations for enhancing aerobic and anaerobic performance in table tennis by improving cardio-metabolic and neuro-muscular fitness, anthropometry and nutritional strategies. Therefore, this review article attempts to narratively provide an overview of the physiology of table tennis by describing the metabolic mechanisms underlying match play and outlining a framework for practical recommendations for improving cardio-metabolic and neuro-muscular fitness, anthropometry as well as nutritional strategies...
June 5, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28573027/operating-length-and-velocity-of-human-m-vastus-lateralis-fascicles-during-vertical-jumping
#15
Maria Elissavet Nikolaidou, Robert Marzilger, Sebastian Bohm, Falk Mersmann, Adamantios Arampatzis
Humans achieve greater jump height during a counter-movement jump (CMJ) than in a squat jump (SJ). However, the crucial difference is the mean mechanical power output during the propulsion phase, which could be determined by intrinsic neuro-muscular mechanisms for power production. We measured M. vastus lateralis (VL) fascicle length changes and activation patterns and assessed the force-length, force-velocity and power-velocity potentials during the jumps. Compared with the SJ, the VL fascicles operated on a more favourable portion of the force-length curve (7% greater force potential, i...
May 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28465161/assessment-of-elisa-as-endpoint-in-neuronal-cell-based-assay-for-bont-detection-using-hipsc-derived-neurons
#16
Sabine Pellett, William H Tepp, Eric A Johnson, Dorothea Sesardic
INTRODUCTION: Botulinum neurotoxins (BoNTs), the causative agents of botulism, are widely used as powerful bio-pharmaceuticals to treat neuro-muscular disorders. Due to the high potency and potential lethality of BoNTs, careful monitoring of the biologic activity of BoNT-based pharmaceuticals is required to ensure safe usage. For decades, the only approved method for potency determination of pharmaceutical BoNTs was the mouse bioassay (MBA), but in recent years improvements in cell-assay technologies have enabled MBA replacement by cell-based assays for specific product evaluations...
November 2017: Journal of Pharmacological and Toxicological Methods
https://www.readbyqxmd.com/read/28456577/evaluation-of-processed-borax-as-antidote-for-aconite-poisoning
#17
Prasanta Kumar Sarkar, Pradeep K Prajapati, Vinay J Shukla, Basavaiah Ravishankar
ETHNOPHARMACOLOGICAL RELEVANCE: Aconite root is very poisonous; causes cardiac arrhythmias, ventricular fibrillation and ventricular tachycardia. There is no specific antidote for aconite poisoning. In Ayurveda, dehydrated borax is mentioned for management of aconite poisoning. AIM OF THE STUDY: The investigation evaluated antidotal effect of processed borax against acute and sub-acute toxicity, cardiac toxicity and neuro-muscular toxicity caused by raw aconite...
April 26, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28449491/characteristics-and-provision-of-care-of-patients-with-the-acute-respiratory-distress-syndrome-descriptive-findings-from-the-dacapo-cohort-baseline-and-comparison-with-international-findings
#18
Frank Dodoo-Schittko, Susanne Brandstetter, Magdalena Brandl, Sebastian Blecha, Michael Quintel, Steffen Weber-Carstens, Stefan Kluge, Patrick Meybohm, Caroline Rolfes, Björn Ellger, Friedhelm Bach, Tobias Welte, Thomas Muders, Kathrin Thomann-Hackner, Thomas Bein, Christian Apfelbacher
BACKGROUND: Little is known about the characteristics and real world life circumstances of ARDS (acute respiratory distress syndrome) patient populations. This knowledge is essential for transferring evidence-based therapy into routine healthcare. The aim of this study was to report socio-demographic and clinical characteristics in an unselected population of ARDS patients and to compare these results to findings from other large ARDS cohorts. METHODS: A German based cross-sectional observational study was carried out...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28268984/exploring-neuro-muscular-synergies-of-reaching-movements-with-unified-independent-component-analysis
#19
Fiorenzo Artoni, Elvira Pirondini, Alessandro Panarese, Silvestre Micera
The coordinated recruitment of group of muscles through muscles synergies is known to simplify the control of movements. However, how and to what extent such control scheme is encoded at a cortical level is poorly understood. So far, electroencephalography (EEG) and electromyography (EMG) have been used, separately, to investigate the cortical regions of the human brain which may be involved in activating muscle synergies. Here we aim at extending these results by looking for a hierarchical relationship between cortical and muscular sources of activity (neuro-muscular synergies) with a unified analysis of independent components (IC) simultaneously extracted from both EEG and EMG signals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227194/exploring-neuro-muscular-synergies-of-reaching-movements-with-unified-independent-component-analysis
#20
Fiorenzo Artoni, Elvira Pirondini, Alessandro Panarese, Silvestre Micera, Fiorenzo Artoni, Elvira Pirondini, Alessandro Panarese, Silvestre Micera, Elvira Pirondini, Alessandro Panarese, Fiorenzo Artoni, Silvestro Micera
The coordinated recruitment of group of muscles through muscles synergies is known to simplify the control of movements. However, how and to what extent such control scheme is encoded at a cortical level is poorly understood. So far, electroencephalography (EEG) and electromyography (EMG) have been used, separately, to investigate the cortical regions of the human brain which may be involved in activating muscle synergies. Here we aim at extending these results by looking for a hierarchical relationship between cortical and muscular sources of activity (neuro-muscular synergies) with a unified analysis of independent components (IC) simultaneously extracted from both EEG and EMG signals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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