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retina psychiatry

Mohamed A Khalil, Alia A Saleh, Sherif M Gohar, Dalia Hamed Khalil, Mohamed Said
BACKGROUND: Research in bipolar disorder suggests the presence of structural brain abnormalities. It is not clear whether these findings are trait markers or operate with the onset and progress with disease severity and duration. Optical coherence tomography (OCT) is a non-invasive technique that detects degenerative changes in the retina reflecting brain degeneration. This study aimed at detecting these changes and relating them to disease severity and clinical characteristics. METHODS: A case-control study conducted in Psychiatry and Addiction Medicine hospital, Faculty of Medicine at Cairo University...
April 28, 2017: Journal of Affective Disorders
Thomas Schwitzer, Raymund Schwan, Emanuel Bubl, Laurence Lalanne, Karine Angioi-Duprez, Vincent Laprevote
Psychiatry and neuroscience research need novel approaches to indirectly investigate brain function. As the retina is an anatomical and developmental extension of the central nervous system (CNS), changes in retinal function may reflect neurological dysfunctions in psychiatric disorders. The last and most integrated retinal relay before visual information transfer to the brain is the ganglion cell layer. Here, based on collected arguments, we argue that these cells offer a crucial site for indirectly investigating brain function...
March 20, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
Shyamal C Bir, Tanmoy Kumar Maiti, Papireddy Bollam, Anil Nanda
INTRODUCTION: Felix Platter is one of the pioneer anatomists and physicians of the 16th century who described various human diseases including meningioma. In this historical article, we present the details of Platter's life and his pioneering work on meningioma. FIRST CASE OF MENINGIOMA: In 1614, Dr. Platter described the first case of meningioma. He described the tumor as a round, fleshy mass shaped like an acorn and as large as a medium-sized apple, and full of holes...
July 2015: Clinical Neurology and Neurosurgery
C Schönfeldt-Lecuona, A Schmidt, E H Pinkhardt, F Lauda, B J Connemann, R W Freudenmann, M Gahr
Optical coherence tomography (OCT) is a non-invasive, contact-less imaging method which provides an "in vivo" representation of the retina. It allows the quantitative measurement of retinal nerve fibre layer thickness (RNFLT) and macula thickness (MT) and, in addition, is suitable to measure volumes (e.g., macula volume/MV). In the research of neurodegenerative diseases, OCT has been increasingly used and has shown its potential as a possible diagnostic tool over the course of the last few years. In recent years, the hypothesis that mental disorders like schizophrenia or unipolar depressive disorder have a degenerative component was established through a variety of volumetric MRI studies...
October 2014: Fortschritte der Neurologie-Psychiatrie
Barry W Rovner, Robin J Casten, Mark T Hegel, Robert W Massof, Benjamin E Leiby, Allen C Ho, William S Tasman
PURPOSE: To compare the efficacy of behavior activation (BA) + low vision rehabilitation (LVR) with supportive therapy (ST) + LVR to prevent depressive disorders in patients with age-related macular degeneration (AMD). DESIGN: Single-masked, attention-controlled, randomized, clinical trial with outcome assessment at 4 months. PARTICIPANTS: Patients with AMD and subsyndromal depressive symptoms attending retina practices (n = 188). INTERVENTIONS: Before randomization, all subjects had 2 outpatient LVR visits, and were then randomized to in-home BA+LVR or ST+LVR...
November 2014: Ophthalmology
Joëlle Lavoie, Michel Maziade, Marc Hébert
Investigating the living brain remains one of the major obstacles in psychiatry research in order to better understand the biological underpinning of brain disorders. Novel approaches are needed to study brain functions indirectly. Since it is part of the central nervous system, retinal functions as measured with the flash electroretinogram (ERG) may reflect the central dysfunctions reported in psychiatric disorders. This review describes the flash ERG anomalies reported in patients with psychiatric disorders such as seasonal affective disorder, schizophrenia, autism spectrum disorder and drug addiction and discusses how changes in retinal functions might be used as biomarkers for psychiatric disorder as well as a potential aid to diagnosis in psychiatry...
January 3, 2014: Progress in Neuro-psychopharmacology & Biological Psychiatry
K Rajsekar, Y L Rajsekar, S K Chaturvedi
The practice of ophthalmology and psychiatry meet over in several aspects of patient diagnosis, management & therapy. The ophthalmologists should be able to recognise signs and symptoms of psychiatric disorder. Non organic disorders could have ophthalmologic manifestations related both the afferent system and motor system related symptoms. Ophthalmologist should be aware of conditions like functional vision loss and visual field loss, voluntary nystagmus, spasm of near reflex, non-organic disturbances of eyelid function, ocular and facial sensation and psychosomatic diseases of eye...
July 1999: Indian Journal of Psychiatry
Stephen A Madill, Gerassimos Lascaratos, Geoffrey B Arden, Dominic H ffytche
BACKGROUND: We sought to determine whether the change in cortical excitability secondary to deafferentation in patients with Charles Bonnet Syndrome (CBS) who hallucinate in a predominant color or combination of colors is related to an alteration in color contrast thresholds and whether the change is specific to the color of the hallucination. METHODS: We prospectively categorized each patient's hallucinations using the Institute of Psychiatry Visual Hallucinations Interview...
September 2009: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
No abstract text is available yet for this article.
December 1963: Klinische Monatsblätter Für Augenheilkunde
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