keyword
MENU ▼
Read by QxMD icon Read
search

ovarian lesions

keyword
https://www.readbyqxmd.com/read/29786517/estrogen-receptor-%C3%AE-potential-target-for-therapy-in-adult-granulosa-cell-tumors
#1
Alessandra Ciucci, Gabriella Ferrandina, Floriana Mascilini, Flavia Filippetti, Giovanni Scambia, Gian Franco Zannoni, Daniela Gallo
OBJECTIVE: Adult granulosa cell tumor (AGCT) is a rare form of sex-cord stromal ovarian tumors. Due to their origin, AGCTs secrete estrogens, and thus, estrogen receptor (ER)-mediated signaling has been considered as a possible target for therapy. The aim of the present study was to get insights into estrogen receptor status and activity in AGCTs, as a strategy to provide molecular support for personalized hormonal treatments. METHODS: We evaluated by immunohistochemistry the expression of ERα, ERβ isoforms (i...
May 18, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29786043/risk-factors-for-recurrence-of-ovarian-endometriosis-in-chinese-patients-aged-45-and-over
#2
Zheng-Xing He, Ting-Ting Sun, Shu Wang, Hong-Hui Shi, Qing-Bo Fan, Lan Zhu, Jin-Hua Leng, Da-Wei Sun, Jian Sun, Jing-He Lang
Background: When considering the issue of recurrence, perimenopausal women may have more dilemma during management comparing with young women, for example, whether to retain the uterus and ovary during surgery, whether it is necessary to add adjuvant medicine treatment after operation, and there is no evidence for reference about using of gonadotropin-releasing hormone agonist. This study aimed to study the risk factors for the recurrence of ovarian endometriosis (EM) in patients aged 45 and over...
June 5, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29771717/prognostic-predictive-value-of-preoperative-intratumoral-2-deoxy-2-18f-fluoro-d-glucose-uptake-heterogeneity-in-patients-with-high-grade-serous-ovarian-cancer
#3
Shuai Liu, Zheng Feng, Zhaoxia Jiang, Hao Wen, Junyan Xu, Herong Pan, Yu Deng, Lei Zhang, Xingzhu Ju, Xiaojun Chen, Xiaohua Wu
OBJECTIVE: This study aimed to explore the clinical and prognostic significance of pretreatment positron-emission tomography/computed tomography (PET/CT) parameters, especially 2-deoxy-2-(F)fluoro-D-glucose-based heterogeneity, in high-grade serous ovarian cancer (HGSC). MATERIALS AND METHODS: We retrospectively investigated 56 patients with HGSC who underwent PET/CT before primary surgery at our hospital between January 2010 and June 2015. None of these patients received neoadjuvant chemotherapy...
May 16, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29770630/survival-impact-of-low-anterior-resection-in-patients-with-epithelial-ovarian-cancer-grossly-confined-to-the-pelvic-cavity-a-korean-multicenter-study
#4
Miseon Kim, Dong Hoon Suh, Jeong Yeol Park, E Sun Paik, Seungmee Lee, Kyung Jin Eoh, Joo Hyun Nam, Yoo Young Lee, Jae Weon Kim, Sunghoon Kim
OBJECTIVE: To evaluate survival impact of low anterior resection (LAR) in patients with epithelial ovarian cancer (EOC) grossly confined to the pelvis. METHODS: We retrospectively reviewed 397 patients who underwent primary staging surgery for treatment of 2014 International Federation of Gynecology and Obstetrics (FIGO) stage II-IIIA EOC: 116 (29.2%) IIA, 212 (53.4%) IIB, and 69 (17.4%) IIIA. Patients with grossly enlarged retroperitoneal lymph nodes positive for metastatic carcinoma were excluded...
April 13, 2018: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29759073/laparoscopic-splenectomy-for-solitary-splenic-metastasis-in-a-patient-with-ovarian-cancer-with-a-long-disease-free-interval-a-case-report
#5
Katsuhiko Yasuda, Tomoo Yoshimura, Hiroaki Kitade, Hidesuke Yanagida, Naoki Hosaka
BACKGROUND: In general, splenic metastasis of epithelial ovarian cancer is considered a terminal stage resulting in widespread metastasis. Solitary splenic metastasis of epithelial ovarian cancer is rare in patients with post-treatment ovarian cancer with long disease-free intervals. CASE PRESENTATION: We report a case of a 62-year-old Japanese woman who presented with elevated serum cancer antigen 125 due to a solitary splenic metastasis of ovarian cancer. She underwent primary open cytoreduction including resection of the right ovarian cancer and postoperative chemotherapy, followed by secondary open cytoreduction and additional postoperative chemotherapy...
May 15, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29756706/ovarian-masses-in-infant-juvenile-age
#6
Kaan Sonmez, Zafer Turkyilmaz, Ramazan Karabulut, A Can Basaklar
INTRODUCTION: The appropraite surgical treatment to pediatric patients with ovarian lesions are heterogeneous and ovarian preservation is desirable in children. The aim of this study is to the discuss findings related to a set of patients who were operated on for ovarian lesions. PATIENTS AND METHODS: A retrospective study carried out in 13 years on 56 patients under the age of 17. These patients were divided into 3 groups according to ovarian pathologic diagnosis: 25 with functional (cyts and torsion), 18 with epithelial ovarian lesions and 13 with germ cell tumours...
June 1, 2018: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/29754696/follicle-stimulating-hormone-receptor-protein-is-expressed-in-ovine-uterus-during-the-estrous-cycle-and-utero-placenta-during-early-pregnancy-an-immunohistochemical-study
#7
Anna T Grazul-Bilska, Arshi Reyaz, Veselina Valkov, Sheri T Dorsam, Dale A Redmer
Follicle stimulating hormone (FSH) is a well characterized gonadotropin that controls primarily development and functions of ovarian follicles in mammalian species. FSH binds to a specific G protein-coupled receptor (FSHR) belonging to the glycoprotein hormone receptor family that plays an essential role in reproduction. Although the primary location of FSHR is in the gonads (mainly in ovarian follicles), FSHR protein and/or mRNA have also been detected in extragonadal female reproductive tissues including embryo, placenta, endometrium, cervix, ovarian cancer tissues, and/or endometriotic lesions in several species...
May 11, 2018: Acta Histochemica
https://www.readbyqxmd.com/read/29753662/clinical-value-of-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-in-response-evaluation-after-primary-treatment-of-advanced-epithelial-ovarian-cancer
#8
J Hynninen, M Laasik, T Vallius, J Kemppainen, S Grönroos, J Virtanen, J Casado, S Hautaniemi, S Grenman, M Seppänen, A Auranen
AIMS: To prospectively evaluate the use of 18 F-fluorodeoxyglucose positron emission tomography/computed tomography (18 F-FDG-PET/CT) in the definition of the treatment response after primary treatment of advanced epithelial ovarian cancer (EOC). MATERIALS AND METHODS: Forty-nine patients with advanced EOC had an 18 F-FDG PET/CT scan before and after primary treatment. The treatment response was defined with the currently used radiological and serological Response Criteria in Solid Tumors (RECIST1...
May 9, 2018: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/29750707/secondary-tumors-of-the-gynecologic-tract-a-clinicopathologic-analysis
#9
Georgia Karpathiou, Celine Chauleur, Sirine Hathroubi, Michel Peoc'h
Although the spread of extragenital tumors to individual female genital tract organs, particularly the ovary, has been much studied, histologic data with regard to secondary tumors involving the whole gynecologic tract are largely lacking. Thus, the aim of the study was to investigate the pathologic and clinical features of these tumors in order to better understand their features. This is a retrospective study of 196 secondary lesions involving the gynecologic tract. The parameters studied were the primary site, its histologic type and grade, the presence of mucous production, the type of secondary involvement, defined as distant metastasis, direct extension or locoregional recurrence, and the time to metastasis...
May 10, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29750706/immunohistochemical-analysis-of-somatostatin-receptors-in-endometriosis-tissue-samples-a-retrospective-study
#10
Maxime Fastrez, Camille Marchisello, Marc Rassy, Serge Rozenberg, Nicolas Sirtaine
Three types of endometriosis are described: superficial peritoneal endometriosis (SPE), ovarian endometrioma (OMA), and deep infiltrating endometriosis (DIE). The expression of somatostatin receptors (SSTR1, 2, and 5) in human endometrial tissue and its ectopic form has been previously studied and may be different in each type of endometriosis. The aim of this study was to assess the immunohistochemical expression of SSTR1, 2, and 5 in tissue samples of SPE, OMA, and DIE. We performed a retrospective analysis in the pathology department database...
May 10, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29749474/pgc1%C3%AE-promotes-cisplatin-resistance-in-human-ovarian-carcinoma-cells-through-upregulation-of-mitochondrial-biogenesis
#11
Luyan Shen, Boyang Sun, Jiyao Sheng, Sihang Yu, Yanqing Li, Huadan Xu, Jing Su, Liankun Sun
The induction of lesions in nuclear and mitochondrial DNA by cisplatin is only a small component of its cytostatic/cytotoxic activity. The signaling pathway network in the nucleus and cytoplasm may contribute to chemotherapeutic resistance. Peroxisome proliferator-activated receptor-coactivator 1α (PGC1α)-mediated mitochondrial biogenesis regulates mitochondrial structural and the functional adaptive response against chemotherapeutic stress, and may be a therapeutic target. However, this regulatory network is complex and depends upon tumor types and environments, which require further investigation...
May 9, 2018: International Journal of Oncology
https://www.readbyqxmd.com/read/29749055/aars2-related-ovarioleukodystrophy-clinical-and-neuroimaging-features-of-three-new-cases
#12
I Taglia, I Di Donato, S Bianchi, A Cerase, L Monti, R Marconi, A Orrico, A Rufa, A Federico, M T Dotti
INTRODUCTION: Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), previously known as hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) or pigmentary orthochromatic leukodystrophy (POLD), is the most frequent non-vascular adult-onset leukoencephalopathy. It is caused by autosomal dominant mutations in CSF1R gene. Recently, also autosomal recessive mutations in AARS2 gene were found to be the cause of an adult-onset leukodystrophy with axonal spheroids...
May 10, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29747214/intestinal-perforation-due-to-deep-infiltrating-endometriosis-during-pregnancy-case-report
#13
Márcia Mendonça Carneiro, Luciana Maria Pyramo Costa, Maria Das Graças Torres, Patrícia Salomé Gouvea, Ivete de Ávila
We report the case of a 33 year-old woman who complained of severe dysmenorrhea since menarche. From 2003 to 2009, she underwent 4 laparoscopies for the treatment of pain associated with endometriosis. After all four interventions, the pain recurred despite the use of gonadotropin-releasing hormone (GnRH) analogues and the insertion of a levonorgestrel intrauterine system (LNG-IUS). Finally, a colonoscopy performed in 2010 revealed rectosigmoid stenosis probably due to extrinsic compression. The patient was advised to get pregnant before treating the intestinal lesion...
April 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29745088/the-diagnostic-prediction-of-postoperative-recurrence-and-prognostic-value-of-he4-in-epithelial-ovarian-cancer
#14
Longyi Chen, Xiuwei Yang, Xiariwana Abasi, Gulinaer Shapaer, Ayinuer Aizimu, Shuping Zhang, Yingxiang Wan, Xiamuxi Kamaer, Tuoluniayi Tuerxun, Reyihanguli Abula, Qingyue Zhang
PURPOSE: To explore the clinical value of the level of human epididymis protein 4 (HE4) in serum in the diagnosis, prediction of postoperative recurrence and prognosis of epithelial ovarian cancer (EOC). METHODS: A total of 103 EOC patients and 121 individuals with benign ovarian lesions were selected. All of them were admitted to our hospital between January 2013 and January 2014 as group A (EOC, n=103) and group B (benign ovarian lesions, n=121), respectively...
March 2018: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/29744056/bilateral-ovarian-masses-with-different-histopathology-in-each-ovary
#15
Saeed Baradwan, Haneen Alalyani, Amira Baradwan, Afnan Baradwan, Maram Al-Ghamdi, Jameel Alnemari, Dania Al-Jaroudi
We document the rare occurrence of multiple primary benign lesions that can occur in bilateral ovarian masses with benign imaging appearances and tumor markers. In addition, this case report contributes important information that may aid physicians in guiding their patients to make optimal clinical decisions together.
May 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29742675/risk-of-gynecologic-cancer-according-to-the-type-of-endometriosis
#16
Liisu Saavalainen, Heini Lassus, Anna But, Aila Tiitinen, Päivi Härkki, Mika Gissler, Eero Pukkala, Oskari Heikinheimo
OBJECTIVE: To assess the risks of gynecologic cancer according to the type of endometriosis in women with surgically verified endometriosis. METHODS: This is a population-based study of women with surgically verified endometriosis retrieved from the Finnish Hospital Discharge Register 1987-2012 (N=49,933); the subtypes of ovarian (n=23,210), peritoneal (n=20,187), and deep infiltrating (n=2,372) endometriosis were analyzed separately. Gynecologic cancers were obtained from the Finnish Cancer Registry...
May 7, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29737910/in-vitro-and-in-vivo-evaluation-of-a-novel-folate-targeted-theranostic-nanoemulsion-of-docetaxel-for-imaging-and-improved-anticancer-activity-against-ovarian-cancers
#17
Niravkumar R Patel, Aleksandr Piroyan, Srinivas Ganta, Allison B Morse, Katie M Candiloro, April L Solon, Abbegail H Nack, Corin A Galati, Collete Bora, Marisa A Maglaty, Shane W O'Brien, Samuel Litwin, Barbara Davis, Denise C Connolly, Timothy P Coleman
Ovarian cancer ranks fifth in cancer related deaths for women in USA. The high mortality rate associated with ovarian cancer is due to diagnosis at later stages of disease and the high recurrence rate of 60-80%. Recurrent ovarian cancers are more likely to present as multidrug resistance (MDR) leading to unfavorable response from 2nd and 3rd line chemotherapy. Nanoemulsions (NEs) are emerging as an attractive drug delivery system to overcome MDR challenges. NEs can also minimize exposure of therapeutic cargo to normal tissues potentially reducing side effects...
May 8, 2018: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/29735801/mucinous-cystic-neoplasm-of-the-liver-or-intraductal-papillary-mucinous-neoplasm-of-the-bile-duct-a-case-report-and-a-review-of-literature
#18
Lumir Kunovsky, Zdenek Kala, Roman Svaton, Vladimir Prochazka, Jan Mazanec, Jakub Husty, Petr Moravcik
Mucinous cystic neoplasm of the liver (MCN-L) and intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) are diagnoses that were classified by the World Health Organization in 2010 as mucin-producing bile duct tumors of the hepatobiliary system. The preoperative differential diagnosis between these two entities is difficult; the presence of a communication with the bile duct is usually considered as a typical sign of IPMN-B. However, the presence of an ovarian-like stroma (OLS) has been established to define the diagnosis of MCN-L...
April 9, 2018: Annals of Hepatology
https://www.readbyqxmd.com/read/29731507/primary-papillary-serous-carcinoma-of-the-fallopian-tube-presenting-as-a-vaginal-mass-a-case-report-and-review-of-the-literature
#19
Einav Kadour-Peero, Lena Sagi-Dain, Gil Cohen, Roman Korobochka, Abed Agbarya, Jacob Bejar, Shlomi Sagi
BACKGROUND There is now evidence to support that some cases of high-grade serous papillary carcinoma arise from the fallopian tubes rather than the ovaries. Common symptoms at presentation include abdominal pain and swelling, vomiting, altered bowel habit and urinary symptoms. To our knowledge, this is the first case of serous papillary carcinoma presenting as a vaginal mass lesion. CASE REPORT A 41-year-old woman was referred to the Bnai-Zion Medical Center with the main complaint of irregular vaginal bleeding, vaginal mucous discharge, and suspected pelvic mass...
May 7, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29731206/recommendation-patterns-among-gynaecologists-and-radiologists-for-adnexal-masses-on-ultrasound
#20
Nathalie Bleau, Alexandre Gauvreau, Amira El-Messidi, Haim Arie Abenhaim
OBJECTIVE: Ultrasound is the primary modality used to evaluate adnexal lesions. Follow-up recommendations for ovarian cysts remain controversial between gynaecologists and radiologists. The objective of this study was to compare practice patterns for adnexal masses described on ultrasound on the basis of the interpreter's field of specialty. METHODS: This study was conducted within the McGill University Hospital Network at two hospitals that differ in the department of interpretation of pelvic ultrasounds...
May 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
keyword
keyword
115246
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"