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https://www.readbyqxmd.com/read/29474441/expressive-writing-intervention-and-self-reported-physical-health-out-comes-results-from-a-nationwide-randomized-controlled-trial-with-breast-cancer-patients
#1
Mikael B Jensen-Johansen, Mia S O'Toole, Søren Christensen, Heiddis Valdimarsdottir, Sandra Zakowski, Dana H Bovbjerg, Anders B Jensen, Robert Zachariae
The objective was to examine the effect of Expressive Writing Intervention (EWI) on self-reported physical symptoms and healthcare utilization in a nationwide randomized controlled trial with Danish women treated for primary breast cancer, and to explore participant characteristics related to emotion regulation as possible moderators of the effect. Women who had recently completed treatment for primary breast cancer (n = 507) were randomly assigned to three 20 min. home-based writing exercises, one week apart, focusing on emotional disclosure (EWI) of a distressing experience (their cancer or a non-cancer topic) or a non-disclosing topic (control)...
2018: PloS One
https://www.readbyqxmd.com/read/29455301/sexual-functioning-among-early-post-treatment-breast-cancer-survivors
#2
Nancy E Avis, Aimee Johnson, Mollie Rose Canzona, Beverly J Levine
PURPOSE: This study aims (1) to estimate percentages of partnered women who are sexually active over the first 2 years post-breast cancer diagnosis; (2) to identify factors related to sexual inactivity; and (3) to evaluate separately, among both sexually active and inactive survivors, the relation between sexual problems and treatment-related variables, symptoms, and psychosocial factors. METHODS: Longitudinal observational study of breast cancer survivors recruited within 8 months of cancer diagnosis and followed for 18 months...
February 17, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29433784/do-cancer-patients-change-their-diet-in-the-e-health-information-era-a-review-of-the-literature-and-a-survey-as-a-proposal-for-the-italian-population
#3
F Ghelfi, M Tieri, S Gori, F Nicolis, M C Petrella, A Filiberti, G Apolone, L Titta
In recent years, there has been an explosion in the amount of available information on cancer in parallel with an ever-increasing number of cancer survivors. Cancer patients and long-term survivors are known to be more sensitive to health-related information and dietary changes could represent a potential consequence of this huge availability of messages. In our review about dietary changes after cancer diagnosis, we found that this topic is particularly investigated among the breast cancer population. The literature examined show that breast cancer patients modify their eating habits after diagnosis in a percentage that varies between approximately 30% and 60%...
February 2018: Food Research International
https://www.readbyqxmd.com/read/29428830/the-effect-of-a-randomized-controlled-physical-activity-trial-on-health-related-quality-of-life-in-metabolically-unhealthy-african-american-women
#4
Teletia Taylor, Chiranjeev Dash, Kepher Makambi, Xiaoyang Ma, Vanessa Sheppard, Lucile L Adams-Campbell
PURPOSE: African-American women have a higher incidence and mortality from breast cancer compared to most other racial/ethnic groups. African-American women are also more likely to be metabolically unhealthy than White women. Several studies have suggested that metabolic syndrome affects health-related quality of life (HRQoL). Despite numerous exercise studies reporting improvements in metabolic syndrome, no study to date has examined the effect of exercise on HRQoL in metabolically unhealthy African-American women...
February 8, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29422254/the-assisi-think-tank-meeting-and-survey-of-post-mastectomy-radiation-therapy-after-breast-reconstruction-the-attm-smart-report
#5
Cynthia Aristei, Orit Kaidar-Person, Luca Tagliaferri, Meritxell Arenas, Charlotte E Coles, Birgitte V Offersen, Giovanni Frezza, Maria Cristina Leonardi, Vincenzo Valentini, Céline Bourgier, Philip M P Poortmans
PURPOSE: To describe the current European practise on post-mastectomy radiation therapy (PMRT) in relation to breast reconstruction. METHODS: A 21-item questionnaire was distributed online via Survey Monkey. Items referred to 1. general topics (country, centre, years of experience in breast cancer); 2. clinical decision making; 3. RT techniques and dosimetry; 4. dose fractionation. RESULTS: 283 responses were received from 19 countries. Most responders worked in public health services and in academic institutions and had 5-20 years experience...
January 12, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29396665/rapid-review-radiomics-and-breast-cancer
#6
REVIEW
Francesca Valdora, Nehmat Houssami, Federica Rossi, Massimo Calabrese, Alberto Stefano Tagliafico
PURPOSE: To perform a rapid review of the recent literature on radiomics and breast cancer (BC). METHODS: A rapid review, a streamlined approach to systematically identify and summarize emerging studies was done (updated 27 September 2017). Clinical studies eligible for inclusion were those that evaluated BC using a radiomics approach and provided data on BC diagnosis (detection or characterization) or BC prognosis (response to therapy, morbidity, mortality), or provided data on technical challenges (software application: open source, repeatability of results)...
February 2, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29378048/associations-between-diet-quality-scores-and-risk-of-postmenopausal-estrogen-receptor-negative-breast-cancer-a-systematic-review
#7
Mengxi Du, Selena H Liu, Cara Mitchell, Teresa T Fung
Background: Estrogen receptor-negative (ER-) breast cancer tends to have poorer prognosis than estrogen receptor-positive breast cancer. A number of studies have examined the association between diet quality as measured by various diet quality scores and the risk of ER- breast cancer. Objective: This systematic review aimed to summarize existing evidence on this topic. Methods: Medline and Embase searches were conducted until 2 April 2017 for cohort and case-control studies on diet quality scores and ER- breast cancer...
January 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29352368/endocrine-therapy-and-related-issues-in-hormone-receptor-positive-early-breast-cancer-a-roundtable-discussion-by-the-breast-cancer-therapy-expert-group-bcteg
#8
REVIEW
Jame Abraham, Humberto Caldera, Robert Coleman, Anthony Elias, Matthew P Goetz, Muaiad Kittaneh, Elyse Lower, Reshma Mahtani, E Terry Mamounas, Mark Pegram, Hope Rugo, Lee Schwartzberg, Tiffany Traina, Chuck Vogel
PURPOSE: Management of breast cancer is a rapidly evolving field, and, although evidence-based guidelines are available for clinicians to provide direction on critical issues in patient care, clinicians often left to address these issues in the context of community practice situations with their patients. These include the patient's comorbid conditions, actual versus perceived benefit of treatments, patient's compliance as well as financial/reimbursement issues, and long-term tolerability of therapy...
January 19, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29311051/relationship-between-state-level-google-online-search-volume-and-cancer-incidence-in-the-united-states-retrospective-study
#9
Charles A Phillips, Allison Barz Leahy, Yimei Li, Marilyn M Schapira, L Charles Bailey, Raina M Merchant
BACKGROUND: In the United States, cancer is common, with high morbidity and mortality; cancer incidence varies between states. Online searches reflect public awareness, which could be driven by the underlying regional cancer epidemiology. OBJECTIVE: The objective of our study was to characterize the relationship between cancer incidence and online Google search volumes in the United States for 6 common cancers. A secondary objective was to evaluate the association of search activity with cancer-related public events and celebrity news coverage...
January 8, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29286986/fractional-microablative-co2-laser-in-breast-cancer-survivors-affected-by-iatrogenic-vulvovaginal-atrophy-after-failure-of-nonestrogenic-local-treatments-a-retrospective-study
#10
Tiziana Pagano, Pasquale De Rosa, Roberta Vallone, Francesco Schettini, Grazia Arpino, Mario Giuliano, Rossella Lauria, Irene De Santo, Alessandro Conforti, Alessandra Gallo, Giovanni Nazzaro, Sabino De Placido, Mariavittoria Locci, Giuseppe De Placido
OBJECTIVE: Vulvovaginal atrophy (VVA) is a condition frequently observed in menopause. Its symptoms can significantly affect the quality of life of patients. Since VVA is related to estrogen deficiency, chemotherapy and hormone therapy for breast cancer (BC) might cause VVA by inducing menopause. Given the lack of effective treatment for VVA in BC survivors, we retrospectively evaluated the efficacy and tolerability of fractional microablative CO2 laser therapy in these patients. METHODS: We treated 82 BC survivors with three cycles of CO2 laser after failure of topical nonestrogenic therapy...
December 28, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29258457/photosensitive-lichenoid-skin-reaction-to-capecitabine
#11
Rena A Shah, Daniel D Bennett, Mark E Burkard
BACKGROUND: Capecitabine is an oral prodrug of fluorouracil, which is a common agent used in the management of many solid tumor malignancies. Dermatologic reaction is common with various chemotherapy agents but is not commonly reported in the use of capecitabine. When adverse reactions of rashes occur, the offending agent is typically removed. We report here an unusual case of photosensitive lichenoid rash due to capecitabine which is managed conservatively without major alteration in treatment...
December 19, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29251680/iranian-women-s-breast-health-seeking-behaviors-husband-s-role
#12
Seyed Saeed Mazloomy-Mahmoodabad, Mahsa Khodayarian, Mohammad Ali Morowatisharifabad, Minoor Lamyian, Hossein Tavangar
BACKGROUND: Breast cancer has become the most common cancer among Yazdi women in Iran. Thus, it is necessary to encourage these women to participate in breast health-seeking behaviors. In this regard, husbands can play an effective role. OBJECTIVE: The aim of this study was to explore women's perceptions about the effect of their husband's role on breast health-seeking protection motivation. METHODS: This study used a directed qualitative content analysis approach based on the Protection Motivation Theory...
December 14, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/29238220/effect-of-statins-on-breast-cancer-recurrence-and-mortality-a-review
#13
REVIEW
Renae D Van Wyhe, Omar M Rahal, Wendy A Woodward
Statins, or 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, are medications that have been used for decades to lower cholesterol and to prevent or treat cardiovascular diseases. Since their approval by the US Food and Drug Administration in the 1980s, other potential uses for statins have been speculated on and explored. Basic science and clinical research suggest that statins are also effective in the management of breast cancer. Specifically, in various breast cancer cell lines, statins increase apoptosis and radiosensitivity, inhibit proliferation and invasion, and decrease the metastatic dissemination of tumors...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/29221997/what-do-patients-want-to-know-questions-and-concerns-regarding-mammography-expressed-through-social-media
#14
Abbas M Charlie, Yiming Gao, Samantha L Heller
PURPOSE: The purpose of this project is to identify questions and concerns patients have regarding breast cancer screening mammography to establish priorities in patient education and health care communication. METHODS: A content analysis of posted questions (June 2010 to February 2017) containing the keywords mammogram and mammography was conducted on the social media question and answer website Quora (Quora Inc, Mountainview, California). Question topic, responses, and number of views were recorded...
December 5, 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29198586/metastases-of-malignant-neoplasms-historical-biological-clinical-considerations
#15
REVIEW
Mark R Wick
The metastasis of neoplastic cells from their site of origin to distant anatomic locations continues to be the principal cause of death from malignant tumors, and that fact has been recognized by physicians for over a century. After the work done by Halsted in the treatment of breast cancer in the 1880s, accepted surgical canon held that metastasis occurred in a linear fashion, with centrifugal "growth in continuity" from the primary neoplasm that first involved regional lymph nodes. Those structures were considered to then be the sources of more distant, visceral metastases...
November 24, 2017: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/29166896/graph-theoretical-comparison-of-normal-and-tumor-networks-in-identifying-brca-genes
#16
Joaquin Dopazo, Cesim Erten
BACKGROUND: Identification of driver genes related to certain types of cancer is an important research topic. Several systems biology approaches have been suggested, in particular for the identification of breast cancer (BRCA) related genes. Such approaches usually rely on differential gene expression and/or mutational landscape data. In some cases interaction network data is also integrated to identify cancer-related modules computationally. RESULTS: We provide a framework for the comparative graph-theoretical analysis of networks integrating the relevant gene expression, mutations, and potein-protein interaction network data...
November 22, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/29111858/women-s-health-endocrine-update
#17
Ekta Kapoor, Stephanie Faubion, Stephanie Hines, Cynthia A Stuenkel
The clinical update serves as a brief review of recently published, high-impact, and potentially practice changing journal articles summarized for our readers. Topics include menopause, sexual dysfunction, breast health, contraception, osteoporosis, and cardiovascular disease. In this clinical update, we selected four recent high-impact publications related to endocrine issues in women. We have chosen to highlight research on subclinical hypothyroidism during pregnancy and adverse pregnancy outcomes, including cognitive outcomes in offspring; the progression of metabolic syndrome severity during the menopausal transition; and the association of diabetes and metformin use with cancer risk and mortality...
November 7, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29083465/management-of-breast-cancer-therapy-related-sexual-dysfunction
#18
Caitlin E Taylor, Jane Lowe Meisel
Sexual dysfunction is a prevalent concern among breast cancer survivors, and is often multifactorial in nature. Causes can be both physiologic and psychological; chemotherapy, endocrine therapy, and disfigurement from breast cancer surgery can all play a role. Sexual dysfunction can have a profound impact on quality of life and relationships and can also impact adherence to endocrine therapy. However, it can be a difficult topic for both patients and providers to bring up, and as a result, it is often inadequately addressed...
October 15, 2017: Oncology (Williston Park, NY)
https://www.readbyqxmd.com/read/29065738/gestational-diabetes-mellitus-and-maternal-breast-cancer-risk-a-meta-analysis-of-the-literature
#19
Chuanbo Xie, Wei Wang, Xiuhong Li, Nan Shao, Weidong Li, Shanghang Xie
OBJECTIVE: The association between gestational diabetes mellitus (GDM) and maternal breast cancer risk was controversial and inclusive. In this study, we aimed to examine the association between GDM and maternal breast cancer using meta-analysis method. METHODS: Researchers searched and reviewed the topic related articles comprehensively. For each eligible article, we extracted the effect size (odds ratio/relative risk or OR/RR) and its 95% confidence interval (CI)...
October 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28989544/local-therapies-for-breast-cancer
#20
REVIEW
Ruth Exner
During the San Antonio Breast Cancer Symposium in December 2016, the main topics were systemic treatment of breast cancer and molecular research. But several studies were also presented concerning local therapy: Surgical issues on evaluating resection margins, management of ductal carcinoma in situ (DCIS), surgical challenges after neoadjuvant therapy related to assessment of response or treatment of axillary lymph nodes, and studies about outcome after breast reconstruction and radiation therapy were discussed...
2017: Memo
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