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https://www.readbyqxmd.com/read/29165148/japan-environment-and-children-s-study-backgrounds-activities-and-future-directions-in-global-perspectives
#1
REVIEW
Kazue Ishitsuka, Shoji F Nakayama, Reiko Kishi, Chisato Mori, Zentaro Yamagata, Yukihiro Ohya, Toshihiro Kawamoto, Michihiro Kamijima
There is worldwide concern about the effects of environmental factors on children's health and development. The Miami Declaration was signed at the G8 Environment Ministers Meeting in 1997 to promote children's environmental health research. The following ministerial meetings continued to emphasize the need to foster children's research. In response to such a worldwide movement, the Ministry of the Environment, Japan (MOE), launched a nationwide birth cohort study with 100,000 pairs of mothers and children, namely, the Japan Environment and Children's Study (JECS), in 2010...
July 14, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29155064/enterprise-deployment-through-a-pulserider-to-treat-an-anterior-communicating-artery-aneurysm-recurrence
#2
Iacopo Valente, Nicola Limbucci, Sergio Nappini, Andrea Rosi, Antonio Laiso, Salvatore Mangiafico
BACKGROUND: PulseRider (Pulsar Vascular, Los Gatos, CA, USA) is a new endovascular device designed to treat wide neck bifurcation intracranial aneurysms. Deployment of a stent through a PulseRider to treat an aneurysm's recurrence has never been described before. CASE DESCRIPTION: We report the case of a 55-year-old man who underwent coiling of a 8 mm anterior communicating artery aneurysm with assistance of a PulseRider neck reconstruction device. The 6-month digital subtraction angiography control showed aneurysm recurrence, so we deployed an Enterprise 2 closed-cell stent (Codman, Miami Lakes, FL, USA) in the A1-A2 segment passing across the previously implanted PulseRider...
November 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29140462/data-portal-for-the-library-of-integrated-network-based-cellular-signatures-lincs-program-integrated-access-to-diverse-large-scale-cellular-perturbation-response-data
#3
Amar Koleti, Raymond Terryn, Vasileios Stathias, Caty Chung, Daniel J Cooper, John P Turner, Dušica Vidovic, Michele Forlin, Tanya T Kelley, Alessandro D'Urso, Bryce K Allen, Denis Torre, Kathleen M Jagodnik, Lily Wang, Sherry L Jenkins, Christopher Mader, Wen Niu, Mehdi Fazel, Naim Mahi, Marcin Pilarczyk, Nicholas Clark, Behrouz Shamsaei, Jarek Meller, Juozas Vasiliauskas, John Reichard, Mario Medvedovic, Avi Ma'ayan, Ajay Pillai, Stephan C Schürer
The Library of Integrated Network-based Cellular Signatures (LINCS) program is a national consortium funded by the NIH to generate a diverse and extensive reference library of cell-based perturbation-response signatures, along with novel data analytics tools to improve our understanding of human diseases at the systems level. In contrast to other large-scale data generation efforts, LINCS Data and Signature Generation Centers (DSGCs) employ a wide range of assay technologies cataloging diverse cellular responses...
November 13, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/29116671/screening-for-zika-virus-in-deceased-organ-donors-in-florida
#4
J Simkins, S Anjan, J A Morillas-Rodriguez, S R Greissman, L M Abbo, J F Camargo, P Ruiz, R Vianna, G Guerra, S Salama, M I Morris
Zika virus (ZIKV) cases have been detected across the United States (US) and locally acquired cases have been reported in Florida. Currently, there are no ZIKV screening guidelines and no data on the incidence among organ donors in the US. This retrospective study was conducted at Jackson Memorial-Miami Transplant Institute. Positive ZIKV tests in local deceased organ donors were investigated from 6/2016 to 1/2017. We evaluated demographics and risk factors for ZIKV infection among organ donors and transplant outcomes among recipients of donors with positive ZIKV testing...
November 8, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/29100226/subclinical-atherosclerosis-among-young-and-middle-aged-adults-using-carotid-intima-media-thickness-measurements
#5
Deborah L Jones, Violeta J Rodriguez, Maria L Alcaide, Nicole Barylski, Digna Cabral, Tatjana Rundek, Stephen M Weiss, Mahendra Kumar
OBJECTIVES: The presence of atherosclerotic plaque in the carotid arteries is a strong predictor of cardiovascular disease (CVD). Research and data on CVD risk have been derived primarily from individuals aged 55 years or older, and assessment of CVD risk among young and middle-aged adults seldom has been studied. The use of ultrasonography to measure carotid intima-media thickness (IMT) and carotid plaque appears to have utility to detect subclinical atherosclerosis in asymptomatic adults...
November 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/29100219/healthcare-utilization-by-frail-community-dwelling-older-veterans-a-1-year-follow-up-study
#6
Miriam Zylberglait Lisigurski, Yolin A Bueno, Chandana Karanam, Allen D Andrade, Sisir Akkineni, Victor Cevallos, Jorge G Ruiz
OBJECTIVES: Frailty is a prevalent clinical syndrome associated with a high risk of adverse health outcomes, including disability, morbidity, and mortality, that has become a major challenge for the healthcare system. The aim of this prospective study was to determine the level of healthcare utilization in prefrail and frail community-dwelling older military veterans. METHODS: We studied a cohort of community-dwelling older veterans aged 65 years and older 1 year at the Miami Veterans Affairs Medical Center to determine their levels of healthcare utilization...
November 2017: Southern Medical Journal
https://www.readbyqxmd.com/read/29093135/epidemiology-of-pediatric-zika-virus-infections
#7
Isabel Griffin, Guoyan Zhang, Danielle Fernandez, Christina Cordero, Teresa Logue, Stephen L White, Anthoni Llau, Lakisha Thomas, Emily Moore, Pedro Noya-Chaveco, Marie Etienne, Mercedes Rojas, Cynthia Goldberg, Genevie Rodriguez, Alvaro Mejia-Echeverry, Edhelene Rico, Leah D Gillis, Marshall Cone, Reynald Jean, Lillian Rivera
BACKGROUND AND OBJECTIVE: In July 2016, local transmission of Zika virus (ZIKV) was announced in Miami-Dade County, Florida. In this report, we describe the epidemiology of pediatric ZIKV infections in locally acquired and travel-associated cases. METHODS: All children aged 1 to 17 years tested for ZIKV between October 1, 2015, and March 29, 2017, were included. SAS 9.4 was used to analyze age, sex, race and/or ethnicity, origin of exposure, onset date, affiliation with a household cluster, clinical symptoms, hospitalizations, viremia, viruria, and antibody detection in specimens...
November 1, 2017: Pediatrics
https://www.readbyqxmd.com/read/29068770/determinants-of-driving-under-the-influence-of-alcohol-or-drugs-among-latino-immigrants-in-miami-dade-county-florida
#8
Eduardo Romano, Mariana Sánchez, Mario De La Rosa, Benjamin Ertman
Little is known about the pre- and postimmigration drinking and drunk- and drugged-driving behavior of Latino immigrants. Despite showing risky drinking behaviors, many recent immigrants of low socioeconomic status (SES) do not drive while impaired by alcohol (DWI) due largely to limited access to a vehicle. This effort examines the DWI and driving while impaired by drugs (DWID) behaviors of Latino immigrants who have access to a vehicle. Data came from an ongoing longitudinal sample of Latino immigrants to Miami-Dade County, Florida...
October 25, 2017: Journal of Ethnicity in Substance Abuse
https://www.readbyqxmd.com/read/29067142/intermittent-96-hour-auricular-electroacupuncture-for-hot-flashes-in-patients-with-prostate-cancer-a-pilot-study
#9
Tyvin Rich, Gerald W Porter, Luisel Ricks-Santi, Tzvi Milshtein, Thomas Corbin
Objective: The hot flash is a common vasomotor disorder that causes distress in menopausal women and that can be debilitating in men with prostate cancer who are treated with androgen deprivation therapy (ADT). The utility of auricular electroacupuncture (AEA) was tested exclusively for a small cohort of men with ADT-induced vasomotor symptoms while the men underwent a course of curative radiotherapy. Materials and Methods: Prior to and during radiotherapy treatment, men with vasomotor symptoms were given repeated questionnaires regarding severity and frequency of hot flashes, quality of life (QoL), and sleep over a 6-week span of an AEA protocol...
October 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/29048113/salicylic-acid-dependent-immunity-contributes-to-resistance-against-rhizoctonia-solani-a-necrotrophic-fungal-agent-of-sheath-blight-in-rice-and-brachypodium-distachyon
#10
Yusuke Kouzai, Mamiko Kimura, Megumi Watanabe, Kazuki Kusunoki, Daiki Osaka, Tomoko Suzuki, Hidenori Matsui, Mikihiro Yamamoto, Yuki Ichinose, Kazuhiro Toyoda, Takakazu Matsuura, Izumi C Mori, Takashi Hirayama, Eiichi Minami, Yoko Nishizawa, Komaki Inoue, Yoshihiko Onda, Keiichi Mochida, Yoshiteru Noutoshi
Rhizoctonia solani is a soil-borne fungus causing sheath blight. In consistent with its necrotrophic life style, no rice cultivars fully resistant to R. solani are known, and agrochemical plant defense activators used for rice blast, which upregulate a phytohormonal salicylic acid (SA)-dependent pathway, are ineffective towards this pathogen. As a result of the unavailability of genetics, the infection process of R. solani remains unclear. We used the model monocotyledonous plants Brachypodium distachyon and rice, and evaluated the effects of phytohormone-induced resistance to R...
October 19, 2017: New Phytologist
https://www.readbyqxmd.com/read/29045273/oneflorida-clinical-research-consortium-linking-a-clinical-and-translational-science-institute-with-a-community-based-distributive-medical-education-model
#11
Elizabeth Shenkman, Myra Hurt, William Hogan, Olveen Carrasquillo, Steven Smith, Andrew Brickman, David Nelson
PROBLEM: Developing a national pragmatic clinical trial infrastructure is central to understanding the effectiveness of interventions applied under usual conditions and where people receive health care. To address this challenge, three Florida universities- the University of Florida Clinical and Translational Science Institute, Florida State University (with its community-based distributive medical education model), and the University of Miami-created (2010-2013) a statewide consortium, the OneFlorida Clinical Research Consortium, to support the conduct of pragmatic clinical trials and provide mentored research experiences for medical and graduate students in real-world practice settings...
October 17, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29043912/latina-young-adults-use-of-health-care-during-initial-months-in-the-united-states
#12
Frank R Dillon, Melissa M Ertl, Dylan A Corp, Rosa Babino, Mario De La Rosa
We examined social ecological predictors of health care utilization among Latina young adults during their initial year after immigration to the United States. Participants were 530 Latinas (ages 18-23) who immigrated to Miami-Dade County, Florida, 11.5 months before assessment. We used multiple logistic regression to test predictors of health care usage. Approximately 36% utilized care. Dimensions of marianismo differentially associated with usage. Usage also was more likely for participants who reported more social network attachment, better health, greater neighborhood cohesion, and possessed a job and health insurance...
October 18, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/29042913/paediatric-virology-as-a-new-educational-initiative-an-interview-with-nobelist-professor-of-virology-harald-zur-hausen
#13
Ioannis N Mammas, Demetrios A Spandidos
Born in Gelsenkirchen-Buer in Germany on March 11th, 1936, Professor Harald zur Hausen, Emeritus Professor of Virology at the University of Freiburg and 2008 Nobel Prize Laureate in Physiology or Medicine for his discovery of human papillomavirus (HPV), which causes cervical cancer, believes that good knowledge of virological methods and diagnostic possibilities are an asset for all young paediatricians. Professor zur Hausen considers that the creation of an educational platform on Paediatric Virology is definitely very beneficial for young paediatricians, as this will greatly enhance their knowledge in the field of Virology...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29041992/understanding-patterns-of-socioeconomic-and-demographic-factors-along-with-health-services-provider-availability-for-zika-outbreak-in-south-florida
#14
Linda McQuade, Mya Rao, Roger Miller, Winnie Zhou, Rinku Deol, Brian Sato
In this study, we analyzed the patterns of socioeconomic and demographic factors along with health services provider availability for the current Zika outbreak in Miami-Dade County, South Florida. We used Center for Consumer Information & Insurance Oversight (CCIIO) Machine-Readable Public Use Files (MR-PUFs) to examine provider availability in combination with socioeconomic and demographic factors that could potentially lead to healthcare disparities between any underserved population of the Wynwood neighborhood and the broader population of Miami-Dade County...
October 18, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/29032001/efficacy-of-self-retained-cryopreserved-amniotic-membrane-for-treatment-of-neuropathic-corneal-pain
#15
Melina I Morkin, Pedram Hamrah
PURPOSE: Treatment of neuropathic corneal pain (NCP) remains intricate, and involves a long-term combined multistep approach. The self-retained cryopreserved amniotic membrane (PROKERA(®), Bio-Tissue, Miami,FL) has been utilized for multiple ocular surface disorders. We evaluate the efficacy, safety, and tolerability of ProKera(®) Slim [PKS] and ProKera(®) Clear [PKC] in the treatment of NCP. METHODS: Retrospective case series of 9 patients who received PKS/PKC for the acute treatment of NCP...
October 12, 2017: Ocular Surface
https://www.readbyqxmd.com/read/29029345/evacuating-people-and-their-pets-older-floridians-need-for-and-proximity-to-pet-friendly-shelters
#16
Rachel Douglas, Ayberk Kocatepe, Anne E Barrett, Eren Erman Ozguven, Clayton Gumber
Objectives: Pets influence evacuation decisions, but little is known about pet-friendly emergency shelters' availability or older adults' need for them. Our study addresses this issue, focusing on the most densely populated area of Florida (Miami-Dade)-the state with the oldest population and greatest hurricane susceptibility. Method: We use Geographic Information Systems (GIS)-based methodology to identify the shortest paths to pet-friendly shelters, based on distance and congested and uncongested travel times-taking into account the older population's spatial distribution...
October 4, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29027672/inside-out-representational-ethics-and-diverse-communities
#17
Miryam Haarlammert, Dina Birman, Ashmeet Oberoi, Wendy Jordana Moore
The purpose of this paper is to write about insights and special considerations for researchers who are, to some degree, "insiders" to the communities they study by expanding on the concept of representational ethics as applied to research in community psychology with diverse and marginalized groups. Representational ethics refers to the ways that researchers, artists, or corporations represent the identities of the people they portray in their communications. As community psychologists we generate and disseminate knowledge about the communities we work with, and in that process, create narratives about the people who participate in our studies...
October 13, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/29027635/international-society-for-clinical-electrophysiology-of-vision-miami-fl-usa-55th-annual-symposium-october-21-26-2017
#18
(no author information available yet)
No abstract text is available yet for this article.
October 13, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29022598/landscape-of-x-chromosome-inactivation-across-human-tissues
#19
Taru Tukiainen, Alexandra-Chloé Villani, Angela Yen, Manuel A Rivas, Jamie L Marshall, Rahul Satija, Matt Aguirre, Laura Gauthier, Mark Fleharty, Andrew Kirby, Beryl B Cummings, Stephane E Castel, Konrad J Karczewski, François Aguet, Andrea Byrnes, Tuuli Lappalainen, Aviv Regev, Kristin G Ardlie, Nir Hacohen, Daniel G MacArthur
X chromosome inactivation (XCI) silences transcription from one of the two X chromosomes in female mammalian cells to balance expression dosage between XX females and XY males. XCI is, however, incomplete in humans: up to one-third of X-chromosomal genes are expressed from both the active and inactive X chromosomes (Xa and Xi, respectively) in female cells, with the degree of 'escape' from inactivation varying between genes and individuals. The extent to which XCI is shared between cells and tissues remains poorly characterized, as does the degree to which incomplete XCI manifests as detectable sex differences in gene expression and phenotypic traits...
October 11, 2017: Nature
https://www.readbyqxmd.com/read/29022597/genetic-effects-on-gene-expression-across-human-tissues
#20
Alexis Battle, Christopher D Brown, Barbara E Engelhardt, Stephen B Montgomery
Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases. The Genotype-Tissue Expression (GTEx) project aims to characterize variation in gene expression levels across individuals and diverse tissues of the human body, many of which are not easily accessible. Here we describe genetic effects on gene expression levels across 44 human tissues. We find that local genetic variation affects gene expression levels for the majority of genes, and we further identify inter-chromosomal genetic effects for 93 genes and 112 loci...
October 11, 2017: Nature
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