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https://www.readbyqxmd.com/read/28545397/jed-a-java-essential-dynamics-program-for-comparative-analysis-of-protein-trajectories
#1
Charles C David, Ettayapuram Ramaprasad Azhagiya Singam, Donald J Jacobs
BACKGROUND: Essential Dynamics (ED) is a common application of principal component analysis (PCA) to extract biologically relevant motions from atomic trajectories of proteins. Covariance and correlation based PCA are two common approaches to determine PCA modes (eigenvectors) and their eigenvalues. Protein dynamics can be characterized in terms of Cartesian coordinates or internal distance pairs. In understanding protein dynamics, a comparison of trajectories taken from a set of proteins for similarity assessment provides insight into conserved mechanisms...
May 25, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28541428/dissociable-roles-of-cerebral-%C3%AE-opioid-and-type-2-dopamine-receptors-in-vicarious-pain-a-combined-pet-fmri-study
#2
Tomi Karjalainen, Henry K Karlsson, Juha M Lahnakoski, Enrico Glerean, Pirjo Nuutila, Iiro P Jääskeläinen, Riitta Hari, Mikko Sams, Lauri Nummenmaa
Neuroimaging studies have shown that seeing others in pain activates brain regions that are involved in first-hand pain, suggesting that shared neuromolecular pathways support processing of first-hand and vicarious pain. We tested whether the dopamine and opioid neurotransmitter systems involved in nociceptive processing also contribute to vicarious pain experience. We used in vivo positron emission tomography to quantify type 2 dopamine and μ-opioid receptor (D2R and MOR, respectively) availabilities in brains of 35 subjects...
May 24, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28531314/the-solanum-tuberosum-kst1-partial-promoter-as-a-tool-for-guard-cell-expression-in-multiple-plant-species
#3
Gilor Kelly, Nitsan Lugassi, Eduard Belausov, Dalia Wolf, Belal Khamaisi, Danja Brandsma, Jayaram Kottapalli, Lena Fidel, Batsheva Ben-Zvi, Aiman Egbaria, Atiako Kwame Acheampong, Chuanlin Zheng, Etti Or, Assaf Distelfeld, Rakefet David-Schwartz, Nir Carmi, David Granot
To date, guard cell promoters have been examined in only a few species, primarily annual dicots. A partial segment of the potato (Solanum tuberosum) KST1 promoter (KST1 partial promoter, KST1ppro) has previously been shown to confer guard cell expression in potato, tomato (Solanum lycopersicum), citrus [Troyer citrange (C. sinensis×Poncirus trifoliata)], and Arabidopsis (Arabidopsis thaliana). Here, we describe an extensive analysis of the expression pattern of KST1ppro in eight (previously reported, as well as new) species from five different angiosperm families, including the Solanaceae and the Cucurbitaceae, Arabidopsis, the monocot barley (Hordeum vulgare), and two perennial species: grapevine (Vitis vinifera) and citrus...
May 22, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28527193/comparison-of-digital-intraoral-scanners-by-single-image-capture-system-and-full-color-movie-system
#4
Meguru Yamamoto, Yu Kataoka, Atsufumi Manabe
BACKGROUND: The use of dental computer-aided design/computer-aided manufacturing (CAD/CAM) restoration is rapidly increasing. OBJECTIVE: This study was performed to evaluate the marginal and internal cement thickness and the adhesive gap of internal cavities comprising CAD/CAM materials using two digital impression acquisition methods and micro-computed tomography. METHODS: Images obtained by a single-image acquisition system (Bluecam Ver...
2017: Bio-medical Materials and Engineering
https://www.readbyqxmd.com/read/28526252/determinants-of-sleep-behavior-in-adolescents-a-pilot-study
#5
Reut Gruber, Gail Somerville, Soukaina Paquin, Johanne Boursier
PURPOSE: To identify determinants of sleep behavior in adolescents of middle to high socioeconomic status. METHODS: Eighteen students (9 boys, 9 girls) with a mean age of 14.9±1.5years were interviewed using a standardized script inspired by the theory of planned behavior. Interviews were audio-recorded and anonymously transcribed verbatim. In addition, participants completed a survey assessing demographic and health characteristics and their sleep duration was measured using actigraphy...
June 2017: Sleep Health
https://www.readbyqxmd.com/read/28522324/non-invasive-three-dimensional-imaging-of-escherichia-coli-k1-infection-using-diffuse-light-imaging-tomography-combined-with-micro-computed-tomography
#6
REVIEW
Luci A Witcomb, Julie Czupryna, Kevin P Francis, Gad Frankel, Peter W Taylor
In contrast to two-dimensional bioluminescence imaging, three dimensional diffuse light imaging tomography with integrated micro-computed tomography (DLIT-μCT) has the potential to realise spatial variations in infection patterns when imaging experimental animals dosed with derivatives of virulent bacteria carrying bioluminescent reporter genes such as the lux operon from the bacterium Photorhabdus luminescens. The method provides an opportunity to precisely localise the bacterial infection sites within the animal and enables the generation of four-dimensional movies of the infection cycle...
May 15, 2017: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/28521155/is-laughter-a-better-vocal-change-detector-than-a-growl
#7
Ana P Pinheiro, Carla Barros, Margarida Vasconcelos, Christian Obermeier, Sonja A Kotz
The capacity to predict what should happen next and to minimize any discrepancy between an expected and an actual sensory input (prediction error) is a central aspect of perception. Particularly in vocal communication, the effective prediction of an auditory input that informs the listener about the emotionality of a speaker is critical. What is currently unknown is how the perceived valence of an emotional vocalization affects the capacity to predict and detect a change in the auditory input. This question was probed in a combined event-related potential (ERP) and time-frequency analysis approach...
April 11, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28515441/fluorescence-dynamics-of-the-biosynthesized-cdse-quantum-dots-in-candida-utilis
#8
Li-Jiao Tian, Nan-Qing Zhou, Xian-Wei Liu, Xing Zhang, Ting-Ting Zhu, Ling-Li Li, Wen-Wei Li, Han-Qing Yu
Organisms served as factories of bio-assembly of nanoparticles attracted a lot of attentions due to the safe, economic and environmental-benignity traits, especially the fabrication of the super fluorescence properties quantum dots (QDs). However, information about the developmental dynamics of QDs in living organisms is still lacking. In this work, we synthesized cadmium-selenium (CdSe) QDs in Candida utilis WSH02-08, and then tracked and quantitatively characterized the developmental dynamics (photoactivation, photostable and photobleaching processes) of bio-QDs by translating fluorescence microscopy movies into visual quantitative curve...
May 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28502415/effects-of-acute-psychological-stress-induced-in-laboratory-on-physiological-responses-in-asthma-populations-a-systematic-review
#9
REVIEW
Annik Plourde, Kim L Lavoie, Candace Raddatz, Simon L Bacon
BACKGROUND: Psychological stress has long been suspected to have a deleterious effect on asthma, with acute psychological stress being associated with physiological responses in asthma patients. OBJECTIVES: The purpose of this systematic review was to provide a narrative synthesis of the impact of acute laboratory psychological stress on physiological responses among asthma patients. METHODS: An extensive search was conducted by two independent authors using Pubmed, PsycINFO, PsyArticles and the Cochrane Library electronic databases (up to September 2016)...
June 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28493518/on-the-relationships-between-dsm-5-dysfunctional-personality-traits-and-social-cognition-deficits-a-study-in-a-sample-of-consecutively-admitted-italian-psychotherapy-patients
#10
Andrea Fossati, Antonella Somma, Robert F Krueger, Kristian E Markon, Serena Borroni
This study aims at testing the hypothesis that the Diagnostic and Statistical Manual of Mental Disorders fifth edition (DSM-5) alternative model of personality disorder (AMPD) traits may be significantly associated with deficits on 2 different social cognition tasks, namely, the Reading the Mind in the Eyes Test and the Movie for the Assessment of Social Cognition, in a sample of consecutively admitted inpatients and outpatients. The sample was composed of 181 consecutively admitted participants (57.5% women; mean age = 38...
May 11, 2017: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/28483261/computational-fluid-dynamics-simulation-of-the-right-subclavian-artery-cannulation
#11
Satoshi Numata, Keiichi Itatani, Hidetake Kawajiri, Sachiko Yamazaki, Keiichi Kanda, Hitoshi Yaku
OBJECTIVE: The purpose of this study was to evaluate the efficacy of right subclavian artery cannulation using computational fluid dynamics. METHODS: Patient-specific models of the aortic arch were made with 4 patterns (1: normal aorta, 2: ascending aorta aneurysm, 3: distal arch aneurysm, 4: bovine arch) based on the computed tomography images. Right subclavian artery and ascending aorta cannulation models were created to simulate the physiologic pulsatile flow...
April 12, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28481074/atomic-resolution-transmission-electron-microscopic-movies-for-study-of-organic-molecules-assemblies-and-reactions-the-first-10-years-of-development
#12
Eiichi Nakamura
A molecule is a quantum mechanical entity. "Watching motions and reactions of a molecule with our eyes" has therefore been a dream of chemists for a century. This dream has come true with the aid of the movies of atomic-resolution transmission electron microscopic (AR-TEM) molecular images through real-time observation of dynamic motions of single organic molecules (denoted hereafter as single-molecule atomic-resolution real-time (SMART) TEM imaging). Since 2007, we have reported movies of a variety of single organic molecules, organometallic molecules, and their assemblies, which are rotating, stretching, and reacting...
May 8, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28478856/continuous-thermographic-observation-may-predict-extravasation-in-chemotherapy-treated-patients
#13
Maiko Oya, Ryoko Murayama, Makoto Oe, Koichi Yabunaka, Hidenori Tanabe, Toshiaki Takahashi, Yuko Matsui, Eiko Otomo, Chieko Komiyama, Hiromi Sanada
PURPOSE: Extravasation, or leakage of vesicant drugs into subcutaneous tissues, causes serious complications such as induration and necrosis in chemotherapy-treated patients. As macroscopic observation may overlook symptoms during infusion, we focused on skin temperature changes at puncture sites and studied thermographic patterns related to induration or necrosis caused by extravasation. METHODS: Outpatients undergoing chemotherapy using peripheral intravenous catheters were enrolled in this prospective observational study...
June 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28475070/2d-3d-display-auto-adjustment-switch-system
#14
Bor-Shyh Lin, Pei-Jung Wu, Chien-Yu Chen
Recently, 2D/3D switchable displays have become the mainstream in 3D display technologies, and people can now watch 3D movies with a naked 2D/3D switchable display at home. However, some studies have indicated that people might encounter visual fatigue after enjoying a 3D film in the theater. Although 2D/3D switchable technologies have been widely developed, 3D display technologies are still lacking in ergonomic and human-care factors such as reducing visual fatigue. This study proposes a novel 2D/3D display auto-adjustment switch system to provide biofeedback functions to reduce users' visual fatigue...
May 3, 2017: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/28472111/spatiotemporal-characteristics-of-gaze-of-children-with-autism-spectrum-disorders-while-looking-at-classroom-scenes
#15
Takahiro Higuchi, Yuko Ishizaki, Atsushi Noritake, Yoshitoki Yanagimoto, Hodaka Kobayashi, Kae Nakamura, Kazunari Kaneko
Children with autism spectrum disorders (ASD) who have neurodevelopmental impairments in social communication often refuse to go to school because of difficulties in learning in class. The exact cause of maladaptation to school in such children is unknown. We hypothesized that these children have difficulty in paying attention to objects at which teachers are pointing. We performed gaze behavior analysis of children with ASD to understand their difficulties in the classroom. The subjects were 26 children with ASD (19 boys and 7 girls; mean age, 8...
2017: PloS One
https://www.readbyqxmd.com/read/28467449/looking-at-reality-versus-watching-screens-media-professionalization-effects-on-the-spontaneous-eyeblink-rate
#16
Celia Andreu-Sánchez, Miguel Ángel Martín-Pascual, Agnès Gruart, José María Delgado-García
This article explores whether there are differences in visual perception of narrative between theatrical performances and screens, and whether media professionalization affects visual perception. We created a live theatrical stimulus and three audio-visual stimuli (each one with a different video editing style) having the same narrative, and displayed them randomly to participants (20 media professionals and 20 non-media professionals). For media professionals, watching movies on screens evoked a significantly lower spontaneous blink rate (SBR) than looking at theatrical performances...
2017: PloS One
https://www.readbyqxmd.com/read/28457681/-the-plague-a-disease-that-is-still-haunting-our-collective-memory
#17
N Peiffer-Smadja, M Thomas
Although the plague has practically disappeared from Europe since the beginning of the 20th century, it is still present in everyone's memory. Owing to three pandemics, it has left an indelible mark on mankind and has given rise to many popular phrases, paintings, books or more recently movies and video games. After a brief description of the plague as a disease, we will try to trace the history of the plague through some of the works of art it inspired and then to show how the plague is still haunting our collective memory...
April 27, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/28454860/assessing-drivers-response-during-automated-driver-support-system-failures-with-non-driving-tasks
#18
Sijun Shen, David M Neyens
INTRODUCTION: With the increase in automated driver support systems, drivers are shifting from operating their vehicles to supervising their automation. As a result, it is important to understand how drivers interact with these automated systems and evaluate their effect on driver responses to safety critical events. This study aimed to identify how drivers responded when experiencing a safety critical event in automated vehicles while also engaged in non-driving tasks. METHOD: In total 48 participants were included in this driving simulator study with two levels of automated driving: (a) driving with no automation and (b) driving with adaptive cruise control (ACC) and lane keeping (LK) systems engaged; and also two levels of a non-driving task (a) watching a movie or (b) no non-driving task...
June 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/28454767/emergence-of-tissue-shape-changes-from-collective-cell-behaviours
#19
REVIEW
Frank Jülicher, Suzanne Eaton
Anyone watching a movie of embryonic development immediately appreciates the importance of morphogenetic movements and cell flows that reshape tissue. Dynamic tissue shape changes are genetically choreographed, but their execution is essentially a mechanical event. How the interplay between genetics and tissue mechanics controls tissue shape is a fundamental question. Key insights into this problem have emerged from studies in different model organisms as well as in cultured epithelia. These studies have revealed how gene expression patterns can generate patterns of planar cell polarity that orient cellular force generation and give rise to anisotropic mechanical properties of cells and tissues...
April 25, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28450273/importance-performance-analysis-of-personal-health-records-in-taiwan-a-web-based-survey
#20
Hsiao-Hsien Rau, Yi-Syuan Wu, Chi-Ming Chu, Fu-Chung Wang, Min-Huei Hsu, Chi-Wen Chang, Kang-Hua Chen, Yen-Liang Lee, Senyeong Kao, Yu-Lung Chiu, Hsyien-Chia Wen, Anis Fuad, Chien-Yeh Hsu, Hung-Wen Chiu
BACKGROUND: Empowering personal health records (PHRs) provides basic human right, awareness, and intention for health promotion. As health care delivery changes toward patient-centered services, PHRs become an indispensable platform for consumers and providers. Recently, the government introduced "My health bank," a Web-based electronic medical records (EMRs) repository for consumers. However, it is not yet a PHR. To date, we do not have a platform that can let patients manage their own PHR...
April 27, 2017: Journal of Medical Internet Research
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