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https://www.readbyqxmd.com/read/28075222/expression-of-myd88-in-adipose-tissue-of-obese-people-is-there-some-role-in-the-development-of-metabolic-syndrome
#1
Ada M Cuevas, Mariana Lazo, Isabel Zuñiga, Fernando Carrasco, Jim J Potter, Veronica Alvarez, Marcos Berry, Fernando Maluenda, Mario Ferrario, Jeanne M Clark
BACKGROUND: The mechanism leading to the development of metabolic complications in obese individuals is not fully understood. Thus, the objective of this study was to examine differences in insulin resistance, inflammation, cytokine and adipokine levels, and expression of selected genes across obese individuals with different number of metabolic syndrome (MetS) components. METHODS: Forty obese individuals who underwent bariatric surgery, divided in three groups based on the number of components of MetS, in addition to abdominal obesity (0, 1, and 2-3 additional components), were studied...
January 11, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28066672/intraoperative-molecular-imaging-to-identify-lung-adenocarcinomas
#2
REVIEW
Andrew D Newton, Gregory T Kennedy, Jarrod D Predina, Philip S Low, Sunil Singhal
Intraoperative molecular imaging is a promising new technology with numerous applications in lung cancer surgery. Accurate identification of small nodules and assessment of tumor margins are two challenges in pulmonary resections for cancer, particularly with increasing use of video-assisted thoracoscopic surgery (VATS). One potential solution to these problems is intraoperative use of a fluorescent contrast agent to improve detection of cancer cells. This technology requires both a targeted fluorescent dye that will selectively accumulate in cancer cells and a specialized imaging system to detect the cells...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28066670/image-guided-thoracoscopic-surgery-with-dye-localization-in-a-hybrid-operating-room
#3
Shun-Mao Yang, Wei-Chun Ko, Mong-Wei Lin, Hsao-Hsun Hsu, Chih-Yang Chan, I-Hui Wu, Yeun-Chung Chang, Jin-Shing Chen
BACKGROUND: The rate of detection of small pulmonary nodules (SPNs) has increased. Thoracoscopic resection following image-guided localization had been a reliable alternative in their treatment. We present our experience with image-guided dye localization using robotic C-arm computed tomography (CT) followed by immediate video-assisted thoracoscopic surgery (VATS) for SPNs in a hybrid operating room (OR). METHODS: From July 2015 to July 2016, 25 consecutive patients with SPNs smaller than 2 cm underwent robotic C-arm CT-guided blue dye tattooing followed by immediate VATS in a hybrid OR...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28066667/preoperative-computed-tomography-guided-dye-injection-to-localize-multiple-lung-nodules-for-video-assisted-thoracoscopic-surgery
#4
Yao-Hui Tseng, Yee-Fan Lee, Min-Shu Hsieh, Ning Chien, Wei-Chun Ko, Jo-Yu Chen, Jang-Ming Lee, Pei-Ming Huang, Mong-Wei Lin, Jin-Shing Chen, Yeun-Chung Chang
BACKGROUND: Preoperative computed tomography (CT)-guided localization of small lung nodules is important for accurate and efficient video-assisted thoracoscopic surgery (VATS). Resection of multiple small pulmonary nodules in one VATS procedure can aid in patient management. The aim of this study was to evaluate the usefulness of CT-guided Patent Blue V (PBV) dye localization in patients with multiple pulmonary nodules who underwent VATS. METHODS: This retrospective study was conducted from January 2013 to December 2015...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28066601/postoperative-predictors-of-ipsilateral-and-contralateral-recurrence-in-patients-with-primary-spontaneous-pneumothorax
#5
Ying-Yi Chen, Hsu-Kai Huang, Hung Chang, Shih-Chun Lee, Tsai-Wang Huang
BACKGROUND: Preventive surgery for contralateral recurrence of primary spontaneous pneumothorax (PSP) remains controversial and few studies discussed both ipsilateral and contralateral recurrences simultaneously. Thus, we aimed to identify the predictors of ipsilateral and contralateral PSP recurrence and to review literatures on the association of blebs/bullae on HRCT with PSP recurrence. METHODS: We retrospectively reviewed consecutive patients who were treated at our hospital for first recurrence of PSP between January 2001 and December 2005...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28063672/c-reactive-protein-crp-as-a-prognostic-factor-for-colorectal-cancer-after-surgical-resection-of-pulmonary-metastases
#6
Cong Li, Qi Xu, Lei Chen, Cong Luo, Jieer Ying, Jinshi Liu
INTRODUCTION: Pulmonary metastases occur in up to 25% of colorectal cancer (CRC) patients. Many studies have reported that pulmonary metastasectomy might increase 5-year survival of these patients. The aim of this study was to describe our experience with pulmonary metastasectomy for metastatic colorectal cancer and to explore the prognostic value of serum C-reactive protein (CRP) and other factors. METHODS: Between June 2002 and December 2013, the clinicopathological data of 88 patients who underwent resection of pulmonary metastases from colorectal carcinoma were retrospectively reviewed and analyzed...
January 4, 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28059973/long-term-survival-based-on-the-surgical-approach-to-lobectomy-for-clinical-stage-i-nonsmall-cell-lung-cancer-comparison-of-robotic-video-assisted-thoracic-surgery-and-thoracotomy-lobectomy
#7
Hao-Xian Yang, Kaitlin M Woo, Camelia S Sima, Manjit S Bains, Prasad S Adusumilli, James Huang, David J Finley, Nabil P Rizk, Valerie W Rusch, David R Jones, Bernard J Park
OBJECTIVE: To compare the long-term outcomes among robotic, video-assisted thoracic surgery (VATS), and open lobectomy in stage I nonsmall cell lung cancer (NSCLC). BACKGROUND: Survival comparisons between robotic, VATS, and open lobectomy in NSCLC have not yet been reported. Some studies have suggested that survival after VATS is superior, for unclear reasons. METHODS: Three cohorts (robotic, VATS, and open) of clinical stage I NSCLC patients were matched by propensity score and compared to assess overall survival (OS) and disease-free survival (DFS)...
February 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28058494/-oncologic-esophageal-resection-and-reconstruction-open-hybrid-minimally-invasive-or-robotic
#8
I Gockel, D Lorenz
Minimally invasive resections are increasingly employed in oncologic surgery for esophageal carcinoma. The new German S3 guideline states that esophagectomy, as well as reconstruction of the esophagus, can be performed minimally invasively or in combination with open techniques (hybrid). However, the current value of different techniques - ranging from complete minimally invasive esophagectomy over hybrid to robotic surgery - remains unregarded.This review provides a critical comparison of these techniques based on current evidence...
January 5, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28043896/marrow-adipose-tissue-composition-in-adults-with-morbid-obesity
#9
Elaine W Yu, Logan Greenblatt, Alireza Eajazi, Martin Torriani, Miriam A Bredella
Patients with type 2 diabetes mellitus (T2DM) have increased fracture risk despite normal or increased bone mineral density (BMD). Elevations in marrow adipose tissue (MAT) and declines in MAT unsaturation are both associated with increased skeletal fragility. The objective of our study was to characterize the quantity and composition of MAT in adults with morbid obesity and T2DM, and to evaluate determinants of MAT. We studied 21 adults with morbid obesity prior to bariatric surgery, 8 of whom had T2DM. All subjects underwent 1H-MR spectroscopy of the lumbar spine and femur for assessment of MAT and dual-energy x-ray absorptiometry (DXA) and quantitative computed tomography (QCT) of the lumbar spine and hip for assessment of areal BMD (aBMD) and volumetric BMD (vBMD)...
December 30, 2016: Bone
https://www.readbyqxmd.com/read/28043480/the-integrated-comprehensive-care-program-a-novel-home-care-initiative-after-major-thoracic-surgery
#10
Yaron Shargall, Wael C Hanna, Laura Schneider, Colin Schieman, Christian J Finley, Anna Tran, Shantel Demay, Carolyn Gosse, James M Bowen, Gord Blackhouse, Kevin Smith
The objective of the study was to evaluate the Integrated Comprehensive Care (ICC) program, a novel health system integration initiative that coordinates home care and hospital-based clinical services for patients undergoing major thoracic surgery relative to traditional home care delivery. Methods included a pilot retrospective cohort analysis that compared the intervention cohort (ICC), composed of all patients undergoing major thoracic surgery in the 2012-2013 fiscal year with a control cohort, who underwent surgery in the year before the initiation of ICC...
July 2016: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28043477/thymectomy-for-myasthenia-gravis-complete-stable-remission-and-associated-prognostic-factors-in-over-1000-cases
#11
Andrew J Kaufman, Justin Palatt, Mark Sivak, Peter Raimondi, Dong-Seok Lee, Andrea Wolf, Fouad Lajam, Faiz Bhora, Raja M Flores
The efficacy of thymectomy and the optimal surgical technique in the treatment of myasthenia gravis (MG) remain controversial. Long-term outcomes are lacking and remission rates are based on small populations. We reviewed our institutional experience of thymectomy for MG focusing on long-term outcomes, complete stable remission (CSR), improvement of symptoms, after transcervical, transsternal, thoracotomy, and VATS thymectomy. A retrospective review of a prospectively maintained database of 3017 patients from 1941-2013 with MG was performed...
July 2016: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28041689/video-assisted-thoracic-surgery-and-anatomical-lung-resections-where-do-we-stand-national-survey-by-the-spanish-society-of-thoracic-surgery
#12
Raul Embun, Néstor Martínez Hernández, Sergi Call, Beatriz de Olaiz Navarro, Jon Zabaleta, Ricard Ramos, Jose Galbis, Nicolás Moreno
INTRODUCTION: The objective of this survey is to find out the cumulated experience and the current situation of video-assisted thoracic surgery (VATS) for anatomical lung resections in Spain. MATERIAL AND METHODS: This is a descriptive study performed from two independent surveys designed through the Survey Monkey(®) web platform. The first survey was aimed at 53 thoracic surgery departments from the public and state-assisted national health system. The second survey, of a personal nature, was directed at 315 thoracic surgeons in active service, including physicians at their residency program...
December 29, 2016: Cirugía Española
https://www.readbyqxmd.com/read/28028308/metastatic-squamous-cell-carcinoma-of-the-pleura-a-rare-complication-of-hidradenitis-suppurativa
#13
Kiran Joglekar, Christopher Jackson, Dipen Kadaria, Amik Sodhi
BACKGROUND Squamous cell carcinoma (SCC), also known as Marjolin ulcer, is a rare complication of hidradenitis suppurativa (HS). Metastatic SCC from HS typically involves the axial skeleton or abdominopelvic viscera. Metastatic disease to the lungs is a rare phenomenon with only three reported cases of lung parenchyma. We present a biopsy proven case of metastatic SCC to the pleura from gluteal HS. CASE REPORT A 46-year-old male with a history of recently diagnosed Marjolin ulcer secondary to gluteal HS was transferred to our intensive care unit for acute hypoxemic respiratory failure secondary to recurrent pleural effusion...
December 28, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/28026848/three-dimensional-ct-angiography-of-the-pulmonary-veins-and-their-anatomical-variations-involvement-in-vats-lobectomy-for-lung-cancer
#14
Alex Fourdrain, Florence De Dominicis, Marie Bensussan, Jules Iquille, Sophie Lafitte, David Michel, Pascal Berna
BACKGROUND: Identification and section of pulmonary veins are an essential part of anatomical pulmonary resections. Intraoperative misunderstandings of pulmonary venous anatomy can lead to serious complications such as bleeding and delayed lung infarction or necrosis. We evaluated principally the rate of pulmonary venous anatomical variations, and secondarily the reliability and clinical outcomes of a preoperative morphological analysis. MATERIALS AND METHODS: Between November 2012 and October 2013, we studied 100 consecutive patients with highly suspected or diagnosed stage I-II primitive lung cancer lesion...
December 27, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/28009427/first-italian-consensus-conference-on-vats-lobectomy-for-nsclc
#15
Mario Nosotti, Andrea Droghetti, Luca Luzzi, Piergiorgio Solli, Roberto Crisci
PURPOSE: Video-assisted thoracoscopic surgery (VATS) lobectomy has become an accepted procedure for the treatment of selected cases of lung cancer. The aim of this project was to establish national practical recommendations for the management of patients suitable for VATS lobectomy. METHODS: The Scientific Committee of the VATS Lobectomy Group (a branch of the Italian Society of Thoracic Surgery) identified the consensus conference as an appropriate tool for a national debate...
December 19, 2016: Tumori
https://www.readbyqxmd.com/read/28008900/-re-operations-in-thoracic-surgery
#16
Amn Kurbonov, F I Makhmadov, K R Nazirboev
AIM: To optimize the outcomes of reoperations for postoperative complications in patients with thoracic diseases and injuries. MATERIAL AND METHODS: The study enrolled 1258 patients with different thoracic diseases and injuries. Postoperatively 58 (4.6%) patients underwent re-thoracotomy and 15 (1.1%) patients - video-assisted interventions for any complications. Indications for re-operations were intrapleural bleeding, bronchial stump failure, esophagogastrostomy insufficiency, prolonged air leak through the drains due to unsealed lung parenchyma, clotted hemothorax...
2016: Khirurgiia
https://www.readbyqxmd.com/read/28007874/new-tubeless-video-assisted-thoracoscopic-surgery-for-small-pulmonary-nodules
#17
Shuben Li, Long Jiang, Keng-Leong Ang, Hanzhang Chen, Qinglong Dong, Hanyu Yang, Jingpei Li, Jianxing He
OBJECTIVE: Problems associated with intubation, chest drainage and urinary catheterization can have a negative impact on patient's recovery after thoracic surgery. We therefore evaluated the feasibility of a new tubeless (spontaneous ventilation without tracheal intubation, urinary catheterization, and no post-operative chest drain placement) approach to perform video-assisted thoracoscopic surgery (VATS) for small pulmonary nodules (SPN) less than 2cm in diameter. METHODS: From 1 January 2012 to 31 December 2014, 34 patients with SPNs were treated using tubeless VATS in our centre...
December 22, 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28003030/prognostic-value-of-p53-for-colorectal-cancer-after-surgical-resection-of-pulmonary-metastases
#18
Cong Li, Qi Xu, Lei Chen, Cong Luo, Yinbo Chen, Jieer Ying
BACKGROUND: Pulmonary metastases occur in up to 25% of colorectal cancer (CRC) patients. Many studies have reported that pulmonary metastasectomy might increase 5-year survival of these patients. The aim of this study was to describe our experience with pulmonary metastasectomy for metastatic colorectal cancer and to explore the prognostic value of p53 overexpression and other factors. METHODS: Between July 2002 and December 2013, the clinicopathological data of 88 patients with colorectal carcinoma who underwent pulmonary metastases resection were retrospectively reviewed and analyzed...
December 21, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28000203/comparison-of-continuous-epidural-block-and-continuous-paravertebral-block-in-postoperative-analgaesia-after-video-assisted-thoracoscopic-surgery-lobectomy-a-randomised-non-inferiority-trial
#19
Sylweriusz Kosiński, Edward Fryźlewicz, Michał Wiłkojć, Adam Ćmiel, Marcin Zieliński
BACKGROUND: Video-assisted (VATS) lung lobectomy can be associated with stronger postoperative pain than is commonly believed. It is generally accepted to introduce multimodal analgaesic strategies based on regional blockade, opioids and non-steroidal anti-inflammatory drugs. However, there is still no consensus regarding the optimal regional technique. The aim of this study was to compare the analgaesic efficacy of continuous thoracic epidural block (TEA) and percutaneous continuous paravertebral block (PVB) in patients undergoing video-assisted lung lobectomy...
2016: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/27999784/a-patient-with-situs-inversus-totalis-and-lung-cancer-a-rare-combination
#20
Konstantinos Grapatsas, Anastasios Piyis, Konstantinos Neofotistos, Zoi Tsilogianni, Paul Zarogoulidis, Dimitrios Paliouras, Apostolos Gogakos, Nikolaos Barbetakis, John Organtzis, Ioannis Kioumis, Konstantinos Porpodis, Wolfgang Hohenforst-Schmidt, Ilias Karapantzos, Chrysa Karapantzou, Kosmas Tsakiridis, Aggeliki Rapti, Charalampos Charalampidis, Konstantinos Kaselouris
Situs inversus totalis (SIT) is a rare clinical entity which is characterized by a complete reverse anatomy of the thoracic cage and abdomen. There are a few reports of patients with SIT and lung cancer. The number of the cases that have been treated surgically is also very small. We report a case of an 80 years old patient who underwent left lower lobectomy after staging with uniportal video-assisted thoracoscopic surgery (VATS) and mediastinoscopy.
November 2016: Annals of Translational Medicine
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