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https://www.readbyqxmd.com/read/29776787/the-value-of-peripheral-perfusion-index-measurements-for-early-detection-of-critical-cardiac-defects
#1
Ozgun Uygur, Ozge Altun Koroglu, Erturk Levent, Merve Tosyali, Mete Akisu, Mehmet Yalaz, Nilgun Kultursay
BACKGROUND: Approximately 25% of congenital heart diseases (CHD) are estimated to be critical and require an intervention. In this study, we aimed to investigate the additional value of peripheral perfusion index (PPI) measurements to pulse oximetry screening for critical CHD (CCHD). METHODS: Infants born at Ege University Hospital between May 2013 and September 2015 were prospectively included in the study. In addition to physical examination, pre- and postductal oxygen saturations and PPI values were measured with a new generation pulse oximeter before discharge from the hospital...
April 12, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29776375/range-wide-genetic-analysis-of-dermacentor-variabilis-and-its-francisella-like-endosymbionts-demonstrates-phylogeographic-concordance-between-both-taxa
#2
Emily L Kaufman, Nathan E Stone, Glen A Scoles, Crystal M Hepp, Joseph D Busch, David M Wagner
BACKGROUND: The American dog tick, Dermacentor variabilis, is an important vector of pathogens to humans, wildlife and domestic animals in North America. Although this tick species is widely distributed in the USA and Canada, knowledge of its range-wide phylogeographic patterns remains incomplete. METHODS: We carried out a phylogenetic analysis of D. variabilis using samples collected from 26 USA states and five Canadian provinces. Tick samples (n = 1053 in total) originated from two main sources: existing archives (2000-2011), and new collections made from 2012 to 2013...
May 18, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29762657/prospects-for-tuberculosis-elimination-in-the-united-states-results-of-a-transmission-dynamic-model
#3
Nicolas A Menzies, Ted Cohen, Andrew N Hill, Reza Yaesoubi, Kara Galer, Emory Wolf, Suzanne M Marks, Joshua A Salomon
We estimated long-term tuberculosis (TB) trends in the US population and assessed prospects for TB elimination. We used a detailed simulation model allowing for changes in TB transmission, immigration, and other TB risk determinants. We evaluated 5 hypothetical scenarios from 2017 to 2100: 1) maintain current TB prevention and treatment activities (base-case), 2) provision of latent TB infection testing and treatment for new legal immigrants, 3) increased uptake of latent TB infection screening and treatment among high-risk populations, including a 3-month isoniazid-rifapentine regimen, 4) improved TB case detection, 5) improved TB treatment quality...
May 14, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29753919/epidemiology-of-orofacial-clefts-in-a-danish-county-over-35-years-before-and-after-implementation-of-a-prenatal-screening-programme-for-congenital-anomalies
#4
Eva Berenth Paaske, Ester Garne
In 2004 the Danish National Board of Health changed its screening recommendations. Since 2005 a first trimester screening for Down syndrome and a prenatal ultrasound screening for congenital anomalies in the second trimester of pregnancy has been offered to all pregnant women. The aim of this study was to describe the prevalence of cleft lip with or without cleft palate and cleft palate in a Danish area and to describe associated anomalies and the development in prenatal diagnosis over time. The study was based on data from the EUROCAT Registry for Funen County...
May 10, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29748542/probiotic-lactobacillus-fermentum-strain-jdfm216-stimulates-the-longevity-and-immune-response-of-caenorhabditis-elegans-through-a-nuclear-hormone-receptor
#5
Mi Ri Park, Sangdon Ryu, Brighton E Maburutse, Nam Su Oh, Sae Hun Kim, Sejong Oh, Seong-Yeop Jeong, Do-Youn Jeong, Sangnam Oh, Younghoon Kim
Here, we examined the functionality of Lactobacillus fermentum strain JDFM216, a newly isolated probiotic bacterium, using a Caenorhabditis elegans model. We determined bacterial colonization in the intestinal tract of C. elegans by plate counting and transmission electron microscopy and examined the survival of C. elegans using a solid killing assay. In addition, we employed DNA microarray analysis, quantitative real time-polymerase chain reaction, and immunoblotting assays to explore health-promoting pathways induced by probiotic bacteria in C...
May 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29742375/investigational-testing-for-zika-virus-among-u-s-blood-donors
#6
MULTICENTER STUDY
Paula Saá, Melanie Proctor, Gregory Foster, David Krysztof, Colleen Winton, Jeffrey M Linnen, Kui Gao, Jaye P Brodsky, Ronald J Limberger, Roger Y Dodd, Susan L Stramer
BACKGROUND: Because of the potential severe clinical consequences of Zika virus (ZIKV) infection, the large numbers of asymptomatic travelers returning from ZIKV-active areas, the detection of ZIKV nucleic acid in blood, and reports of transmission of ZIKV through transfusion, in 2016 the Food and Drug Administration released recommendations for individual-unit nucleic acid testing to minimize the risk of transmission of ZIKV through blood transfusions. METHODS: The American Red Cross implemented investigational screening of donated blood for ZIKV RNA by means of transcription-mediated amplification (TMA)...
May 10, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29705883/systematic-review-of-physical-education-based-physical-activity-interventions-among-elementary-school-children
#7
REVIEW
V L Errisuriz, N M Golaszewski, K Born, J B Bartholomew
Physical education (PE)-based interventions are a popular method to target children's physical activity (PA) and fitness; however, little is known about their effectiveness or what factors lead to successful interventions. This paper: (1) systematically reviews studies examining PE interventions designed to impact PA, fitness, and/or body composition; and (2) makes recommendations for new research directions based upon these findings. Our systematic review was limited to experimental and quasi-experimental studies conducted in elementary schools...
April 28, 2018: Journal of Primary Prevention
https://www.readbyqxmd.com/read/29705560/comparative-subtractive-proteomics-based-ranking-for-antibiotic-targets-against-the-dirtiest-superbug-acinetobacter-baumannii
#8
Sajjad Ahmad, Saad Raza, Reaz Uddin, Syed Sikander Azam
Multidrug-resistant Acinetobacter baumannii is indeed to be the most successful nosocomial pathogen responsible for myriad infections in modern health care system. Computational methodologies based on genomics and proteomics proved to be powerful tools for providing substantial information about different aspects of A. baumannii biology that made it possible to design new approaches for treating multi, extensive and total drug resistant isolates of A. baumannii. In this current approach, 35 completely annotated proteomes of A...
April 21, 2018: Journal of Molecular Graphics & Modelling
https://www.readbyqxmd.com/read/29698931/the-impact-of-a-public-health-department-s-expansion-from-a-one-step-to-a-two-step-refugee-screening-process-on-the-detection-and-initiation-of-treatment-of-latent-tuberculosis
#9
E M Einterz, O Younge, C Hadi
OBJECTIVES: To determine, subsequent to the expansion of a county health department's refugee screening process from a one-step to a two-step process, the change in early loss to follow-up and time to initiation of treatment of new refugees with latent tuberculosis infection (LTBI). STUDY DESIGN: Quasi-experimental, quantitative. METHODS: Review of patient medical records. RESULTS: Among 384 refugees who met the case definition of LTBI without prior tuberculosis (TB) classification, the number of cases lost to early follow-up fell from 12...
April 23, 2018: Public Health
https://www.readbyqxmd.com/read/29698544/the-swiss-cystic-fibrosis-infant-lung-development-scild-cohort
#10
Insa Korten, Elisabeth Kieninger, Sophie Yammine, Nicolas Regamey, Sylvia Nyilas, Kathryn Ramsey, Carmen Casaulta, Philipp Latzin, For The Scild Study Group
The Swiss Cystic Fibrosis Infant Lung Development (SCILD) cohort is a prospective birth cohort study investigating the initiating events of cystic fibrosis lung disease during infancy, and their influence on the trajectory of disease progression throughout early childhood. Infants with cystic fibrosis are recruited throughout Switzerland after diagnosis by new-born screening. It is the first European population-based prospective cohort study of infants with cystic fibrosis taking advantage of a nationwide new-born screening programme...
April 26, 2018: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29695386/the-relationship-between-intimate-partner-violence-reported-at-the-first-antenatal-booking-visit-and-obstetric-and-perinatal-outcomes-in-an-ethnically-diverse-group-of-australian-pregnant-women-a-population-based-study-over-10-years
#11
Hannah Grace Dahlen, Ana Maria Munoz, Virginia Schmied, Charlene Thornton
OBJECTIVES: Intimate partner violence (IPV) is a global health issue affecting mainly women and is known to escalate during pregnancy and impact negatively on obstetric and perinatal outcomes. The aim of this study is to determine the incidence of IPV in a pregnant multicultural population and to determine the relationship between IPV reported at booking interview and maternal and perinatal outcomes. DESIGN: This is a retrospective population-based data study. We analysed routinely collected data (2006-2016) from the ObstetriX system on a cohort of pregnant women...
April 25, 2018: BMJ Open
https://www.readbyqxmd.com/read/29668891/maternal-polycystic-ovarian-syndrome-and-early-offspring-development
#12
Griffith A Bell, Rajeshwari Sundaram, Sunni L Mumford, Hyojun Park, James Mills, Erin M Bell, Miranda Broadney, Edwina H Yeung
STUDY QUESTION: Is maternal polycystic ovarian syndrome (PCOS) associated with developmental delays in offspring? SUMMARY ANSWER: Offspring of mothers with PCOS were at higher risk of failure on the Ages and Stages Questionnaire (ASQ). WHAT IS KNOWN ALREADY: There is growing evidence that offspring of mothers with PCOS may be at higher risk for developmental disorders due to potential exposure to hyperandrogenism and insulin resistance. Few studies exist regarding maternal PCOS and early childhood development in the USA...
April 13, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29663955/using-surveillance-data-to-simulate-the-impact-of-a-hypothetical-pre-entry-tuberculosis-screening-programme-in-japan
#13
L Kawatsu, K Uchimura, K Izumi, A Ohkado, S Kato
BACKGROUND: Despite a growing burden of foreign-born tuberculosis (TB) patients, Japan does not currently practise pre-entry tuberculosis (TB) screening among foreign-born entrants. OBJECTIVE: To evaluate the impact of a hypothetical pre-entry TB screening programme among new foreign-born entrants into Japan. METHOD: Using publicly available sources, we estimated 1) the number of prevalent TB cases, defined as bacteriologically or clinically confirmed cases among new foreign-born entrants into Japan in 2015, and 2) the yield from a hypothetical pre-entry TB screening programme under three scenarios: Scenario A, in which screening would be required of all applicants intending to stay for 3 months; Scenario B, screening among applicants for visas for settlement purposes; and Scenario C, screening among student and technical intern visa applicants...
May 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29661584/strategies-for-increasing-uptake-of-vaccination-in-pregnancy-in-high-income-countries-a-systematic-review
#14
REVIEW
Kate Alexandra Bisset, Pauline Paterson
INTRODUCTION: Vaccination in pregnancy is an effective method to protect against disease for the pregnant woman, foetus and new born infant. In England, it is recommended that pregnant women are vaccinated against pertussis and influenza. Improvement in the uptake of both pertussis and influenza vaccination among pregnant women is needed to prevent morbidity and mortality for both the pregnant women and unborn child. AIM: To identify effective strategies in increasing the uptake of vaccination in pregnancy in high-income countries and to make recommendations for England...
April 13, 2018: Vaccine
https://www.readbyqxmd.com/read/29657956/results-of-a-hepatitis-c-virus-screening-program-of-the-1945-1965-birth-cohort-in-a-large-emergency-department-in-new-jersey
#15
Julia Kang Cornett, Vimal Bodiwala, Victor Razuk, Devangi Shukla, Navaneeth Narayanan
Background: Persons born between 1945 and 1965 account for an estimated 81% of those infected with hepatitis C virus (HCV) in the United States. However, up to 60% remain undiagnosed. Prior studies have reported HCV screening results from large urban emergency departments. Methods: This is a retrospective cohort study of patients in the 1945-1965 birth cohort tested for HCV in a large emergency department (ED) in New Jersey from June 1, 2016, through December 31, 2016...
April 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29649735/a-review-of-analytical-procedures-for-the-simultaneous-determination-of-medically-important-veterinary-antibiotics-in-environmental-water-sample-preparation-liquid-chromatography-and-mass-spectrometry
#16
REVIEW
Chansik Kim, Hong-Duck Ryu, Eu Gene Chung, Yongseok Kim, Jae-Kwan Lee
Medically important (MI) antibiotics are defined by the United States Food and Drug Administration as drugs containing certain active antimicrobial ingredients that are used for the treatment of human diseases or enteric pathogens causing food-borne diseases. The presence of MI antibiotic residues in environmental water is a major concern for both aquatic ecosystems and public health, particularly because of their potential to contribute to the development of antimicrobial-resistant microorganisms. In this article, we present a review of global trends in the sales of veterinary MI antibiotics and the analytical methodologies used for the simultaneous determination of antibiotic residues in environmental water...
April 9, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29594846/prevalence-and-spatial-distribution-of-ixodid-tick-populations-in-the-forest-fringes-of-western-ghats-reported-with-human-cases-of-kyasanur-forest-disease-and-monkey-deaths-in-south-india
#17
C Sadanandane, M D Gokhale, A Elango, P Yadav, D T Mourya, P Jambulingam
Kyasanur forest disease (KFD) is a major tick-borne viral haemorrhagic fever caused by KFD virus (KFDV) (Flaviviridae). The disease was reported to be confined to five districts of Karnataka state India until 2011. During 2012-2016, emergence of KFD has been reported in newer areas of Karnataka and adjoining states. Therefore, survey of tick vectors was carried out in these new areas of Karnataka and adjoining states reported with monkey deaths and human cases of KFD. In all selected sites, ticks from the forest floor were collected by lint clothes using flagging method...
March 28, 2018: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/29571077/neonates-with-congenital-cytomegalovirus-and-hearing-loss-identified-via-the-universal-newborn-hearing-screening-program
#18
William D Rawlinson, Pamela Palasanthiran, Beverly Hall, Laila Al Yazidi, Michael J Cannon, Carolyn Cottier, Wendy J van Zuylen, Monica Wilkinson
BACKGROUND: Congenital cytomegalovirus (CMV) is the most common non-genetic cause of sensorineural hearing loss. Currently, there are no universal CMV screening programs for newborns or routine CMV testing of neonates with hearing loss in Australia, or elsewhere. OBJECTIVES: This study was undertaken to determine the prevalence of congenital CMV infection in infants with hearing loss identified using routine resources via the Australian universal neonatal hearing screening (UNHS) program...
May 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29558984/endemic-exotic-and-novel-apicomplexan-parasites-detected-during-a-national-study-of-ticks-from-companion-animals-in-australia
#19
Telleasha L Greay, Alireza Zahedi, Anna-Sheree Krige, Jadyn M Owens, Robert L Rees, Una M Ryan, Charlotte L Oskam, Peter J Irwin
BACKGROUND: Apicomplexan tick-borne pathogens that cause disease in companion animals include species of Babesia Starcovici, 1893, Cytauxzoon Neitz & Thomas, 1948, Hepatozoon Miller, 1908 and Theileria Bettencourt, Franca & Borges, 1907. The only apicomplexan tick-borne disease of companion animals that is known to occur in Australia is babesiosis, caused by Babesia canis vogeli Reichenow, 1937 and Babesia gibsoni Patton, 1910. However, no molecular investigations have widely investigated members of Apicomplexa Levine, 1980 in Australian ticks that parasitise dogs, cats or horses, until this present investigation...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29544376/acceptability-of-hiv-testing-among-jail-inmates-when-combined-with-a-blood-test-for-tuberculosis
#20
Ank E Nijhawan, Princess A Iroh, Esmaeil Porsa
Incarcerated individuals are at high risk of HIV and tuberculosis (TB), though combined screening in the criminal justice system is limited. Newer blood tests for TB provide a unique opportunity to combine HIV and TB testing in corrections. Entering jail inmates were offered routine opt-out HIV testing along with TB screening, both via blood draw. Of the 529 individuals enrolled, 524 (99%) agreed to HIV testing. Testing identified 13 (2.5%) previously diagnosed HIV infections and one new positive. One quarter (138, 26%) of participants had never been tested for HIV and were more likely to be young, Hispanic, born outside of the United States, and incarcerated for the first time...
January 1, 2018: Journal of Correctional Health Care
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