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Gastric cancer and endoscopy

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https://www.readbyqxmd.com/read/27930534/does-the-interval-of-screening-endoscopy-affect-survival-in-gastric-cancer-patients-a-cross-sectional-study
#1
Jieun Kim, Su Mi Kim, Man Ho Ha, Jeong Eun Seo, Min-Gew Choi, Jun Ho Lee, Tae Sung Sohn, Sung Kim, Sin-Ho Jung, Jae Moon Bae
Gastric cancer remains the second most common cancer in Korea; however, its mortality has decreased due to earlier diagnosis. In Korea, screening endoscopy has been performed nationwide since 1999. The aim of this study was to elucidate the benefit of screening endoscopy on actual survival in gastric cancer patients and to determine the optimal interval of screening endoscopy.We analyzed 1651 patients diagnosed with gastric adenocarcinoma who underwent surgical treatment between June 2008 and December 2014...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27928446/gastrostomy-with-peritoneal-collar-versus-percutaneous-endoscopic-gastrostomy
#2
Tudor C, Branescu C, Savlovschi C, El-Khatib A, Pantu H, Nica A, Dascalu Am, Masoumeh B, Tudor As, Oprescu Sm, Serban D
Aim. The present study aimed to perform a medico-surgical comparative analysis of the 2 most widely used techniques: gastrostomy with peritoneal collar versus percutaneous endoscopic gastrostomy, based on the vast clinical experience in an Upper Digestive Surgery Clinic. Materials and method. A retrospective study was carried out between January 2010 and January 2015 on the patients admitted for a surgical solution for feeding. The indications, preoperative preparation, surgical techniques, and postoperative outcomes were analyzed...
October 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27916772/slow-progression-of-gastric-adenocarcinoma-of-fundic-gland-type-a-case-report
#3
Chiaki Kusumoto, Kenji Shigehara, Susumu Take, Kuniharu Ishiki, Kouhei Taniguchi
Here we report the case of a 73-year-old male who had undergone esophagogastroduodenoscopy (EGD) at a nearby hospital or at our hospital every year since 2006. In 2013, EGD results revealed a discolored lesion, measuring 6mm in diameter, on the anterior side of the upper body in the stomach. Helicobacter pylori (HP) was eradicated in 2010, and the background mucosa around the lesion was endoscopically diagnosed as non-atrophic. We performed endoscopic biopsy of the lesion. Histological examination of the specimen confirmed gastric adenocarcinoma of the fundic gland type...
2016: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/27915451/interobserver-agreement-in-detection-of-white-globe-appearance-and-the-ability-of-educational-lectures-to-improve-the-diagnosis-of-gastric-lesions
#4
Hitoshi Omura, Naohiro Yoshida, Tomoyuki Hayashi, Kazuhiro Miwa, Hajime Takatori, Hirokazu Tsuji, Katsuhisa Inamura, Yukihiro Shirota, Hiroyuki Aoyagi, Takaharu Masunaga, Kazuyoshi Katayanagi, Hiroshi Kurumaya, Shuichi Kaneko, Hisashi Doyama
BACKGROUND: White globe appearance (WGA) refers to a small white lesion of globular shape underneath cancerous gastric epithelium that can be clearly visualized by magnifying endoscopy with narrowband imaging (M-NBI). WGA has been reported to be a novel endoscopic marker that is highly specific in differentiating early gastric cancer (GC) from low-grade adenoma, and has a significantly higher prevalence in early GCs than in noncancerous lesions. However, interobserver agreement in detecting WGA and whether training intervention can improve diagnostic accuracy are unknown...
December 3, 2016: Gastric Cancer
https://www.readbyqxmd.com/read/27895391/characteristics-of-gastric-cancer-detected-within-1-year-after-successful-eradication-of-helicobacter-pylori
#5
Toshihiro Nishizawa, Hidekazu Suzuki, Toru Arano, Shuntaro Yoshida, Hiroharu Yamashita, Keisuke Hata, Takanori Kanai, Naohisa Yahagi, Osamu Toyoshima
Gastric cancers are sometimes diagnosed in patients who have successfully undergone Helicobacter pylori (H. pylori) eradication. We analyzed the clinicopathological features of gastric cancers detected after eradication to clarify their characteristics. We reviewed 31 patients with 34 cases of gastric cancer detected after successful H. pylori eradication. Clinicopathological characteristics analyzed included interval since eradication, interval since last endoscopy, tumor size, and depth of invasion. Patients were classified into two groups: early detection (<1 year since eradication) and delayed detection (≥1 year since eradication)...
November 2016: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/27871804/additional-surgical-resection-after-endoscopic-mucosal-dissection-for-early-gastric-cancer-a-medium-sized-hospital-s-experience
#6
Bunzo Nakata, Masashige Tendo, Masatsugu Okuyama, Kenichi Nakahara, Hirotaka Ishizu, Go Masuda, Tomohiro Lee, Takeshi Hori, Masahiko Ohsawa, Hiroshi Sato, Tetsuro Ishikawa
PURPOSE: In Japan, the majority of early gastric cancers (EGCs) are now treated with endoscopic submucosal dissection (ESD). Patients with non-curative lesions treated by ESD are advised to undergo additional surgical resection (ASR) based on guidelines from the Japan Gastroenterological Endoscopy Society (JGES) and Japanese Gastric Cancer Association (JGCA). However, many studies have demonstrated that residual cancer and lymph node metastasis are only rarely found in ASR specimens. Here we retrospectively analyzed the conditions that could enable the avoidance of unnecessary ASR...
November 15, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27868244/ddw-2016-review-advances-in-therapeutic-upper-gastrointestinal-endoscopy
#7
REVIEW
Shannon Melissa Chan, Baldwin Yeung, Philip Wai Yan Chiu
This editorial provides a review of the lectures and abstracts presented at Digestive Disease Week 2016 in San Diego on advances in therapeutic upper gastrointestinal procedures. There were a significant number of reports on expanded indications for endoscopic submucosal dissection (ESD) of early gastric cancers, advanced endoscopic techniques for resection including submucosal tunnel endoscopic resection (STER) and endoscopic full thickness resection (EFTR), per oral endoscopic myotomy (POEM), and novel endoscopic techniques including antireflux mucosectomy (ARMS) as well as endoscopic suturing...
November 21, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27864714/clinical-features-of-postoperative-anastomotic-bleeding-after-gastrectomy-and-efficacy-of-endoscopic-hemostasis-a-case-control-study
#8
Sunpyo Lee, Ji Yong Ahn, Shin Na, Hee Kyong Na, Kee Wook Jung, Do Hoon Kim, Jeong Hoon Lee, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Seon-Ok Kim
BACKGROUND: Postoperative anastomotic bleeding (PAB) is relatively rare; however, it can be lethal if not treated immediately. The aim of our study was to investigate the clinical features of PAB and the efficacy of endoscopic hemostasis (EH) for PAB. METHODS: Between January 2004 and May 2013, 16,591 patients underwent gastrectomy for gastric cancer at Asan Medical Center. Among them, 36 patients who experienced PAB within 2 months after the gastrectomy were enrolled as a case group...
November 18, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27846453/a-case-report-of-chylous-ascites-after-gastric-bypass-for-morbid-obesity
#9
Esmeralda Capristo, Valerio Spuntarelli, Giorgio Treglia, Vincenzo Arena, Alessandro Giordano, Geltrude Mingrone
INTRODUCTION: We described the case of a highly aggressive antral gastric carcinoma with a scarce symptomatology, in a patient undergone Roux-en-Y Gastric Bypass (RYGB) for obesity. PRESENTATION OF CASE: A 61 year-old white man in apparent good health, who underwent laparoscopic RYGB for obesity 18 months earlier, with a loss of 30kg, reported a sudden abdominal distension and breath shortness with a weight gain of 5kg in few days. Endoscopy of both upper gastro-intestinal tract and the colon were performed along with CT-scan and positron-emission tomography (PET) CT- scan...
November 5, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27845158/the-application-of-nanoparticles-in-diagnosis-and-theranostics-of-gastric-cancer
#10
Rutian Li, Baorui Liu, Jiahui Gao
Gastric cancer is the fourth most common cancer and the second leading cause of cancer related death worldwide. For the diagnosis of gastric cancer, apart from regular systemic imaging, the locoregional imaging is also of great importance. Moreover, there are still other ways for the detecting of gastric cancer, including the early detection of gastric cancer by endoscopy, the detection of gastric-cancer related biomarkers and the detection of circulating tumor cells (CTCs) of gastric cancer. However, conventional diagnostic methods are usually lack of specificity and sensitivity...
November 11, 2016: Cancer Letters
https://www.readbyqxmd.com/read/27844264/does-routine-endoscopy-or-contrast-swallow-study-after-esophagectomy-and-gastric-tube-reconstruction-change-patient-management
#11
N Nederlof, J de Jonge, T de Vringer, T C K Tran, M C W Spaander, H W Tilanus, B P L Wijnhoven
BACKGROUND: Anastomotic leakage is a severe complication after esophagectomy. The objective was to investigate the diagnostic and predictive value of routine contrast swallow study and endoscopy for the detection of anastomotic dehiscence in patients after esophagectomy. METHODS: All patients who underwent contrast swallow and/or endoscopy within 7 days after oesophagectomy for cancer between January 2005 and December 2009 were selected from an institutional database...
November 14, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/27842547/health-related-quality-of-life-in-patients-with-barrett-s-esophagus
#12
Chi-Yang Chang, Lukas Jyuhn-Hsiarn Lee, Jung-Der Wang, Ching-Tai Lee, Chi-Ming Tai, Tao-Qian Tang, Jaw-Town Lin
BACKGROUND: Gastroesophageal reflux disease (GERD) has become a major health problem globally, affecting patients' health-related quality of life (HRQOL). Barrett's esophagus (BE) is a precancerous lesion associated with GERD. BE patients might not only suffer from HRQOL losses by GERD but also face psychological distress due to the increased risk of developing cancer. However, the majority of patients in Asia have shorter BE segment which is different from the West. This study aimed to determine whether the HRQOL in BE patients were worse than in healthy referents in Taiwan...
November 14, 2016: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/27833394/two-cases-of-adenocarcinoma-occurring-in-sporadic-fundic-gland-polyps-observed-by-magnifying-endoscopy-with-narrow-band-imaging
#13
Kazumi Togo, Tetsuya Ueo, Hirotoshi Yonemasu, Hideho Honda, Tetsuya Ishida, Hiroshi Tanabe, Kenshi Yao, Akinori Iwashita, Kazunari Murakami
Gastric fundic gland polyps (FGPs) are common non-adenomatous gastric polyps arising from normal fundic mucosa without Helicobacter pylori (H. pylori) infection. Although systemic FGPs associated with familial adenomatous polyposis (FAP) often have dysplasia, there are few reports of dysplasia occurring in sporadic FGPs, especially when detected by magnifying endoscopy with narrow band imaging (ME-NBI). We experienced two cases of adenocarcinoma occurring in sporadic FGPs, and their ME-NBI findings were very useful for differentiating FGP with cancer from non-dysplastic FGP...
October 28, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27832356/risk-factors-for-intestinal-metaplasia-in-a-southeastern-chinese-population-an-analysis-of-28-745-cases
#14
Jian-Xia Jiang, Qing Liu, Bing Zhao, Hai-Han Zhang, Huai-Ming Sang, Soyfoo-Muhammad Djaleel, Guo-Xin Zhang, Shun-Fu Xu
PURPOSE: To identify risk factors for intestinal metaplasia in a southeastern Chinese population. METHODS: Subjects who underwent upper GI endoscopy and endoscopic biopsy in the First Affiliated Hospital of Nanjing Medical University from 2008 to 2013 were included into this study. Various demographic, geographic, clinical and pathological data were analyzed separately to identify risk factors for intestinal metaplasia. RESULTS: The incidence of intestinal metaplasia differed significantly in 17 municipal areas ranging from 16...
November 10, 2016: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/27821077/a-case-series-of-intestinal-adenomatous-polyposis-of-unidentified-etiology-a-late-effect-of-irradiation
#15
Lisanne Sara Rigter, Frank G J Kallenberg, Barbara Bastiaansen, Theo A M van Os, Floor E van Leeuwen, Monique Esther van Leerdam, Evelien Dekker
BACKGROUND: In a large number of patients with multiple gastrointestinal adenomatous polyps, no causal germline mutation can be found. Non-genetic factors may contribute to the development of adenomatous polyps in these unexplained polyposis patients. In the development of gastrointestinal cancer, prior exposure to abdominal radiotherapy has been identified as such a factor, as it increases the gastrointestinal cancer risk in cancer survivors. A relationship of radiotherapy with intestinal polyposis, however, has not yet been described...
November 8, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27809451/gastric-cancer-and-family-history
#16
REVIEW
Yoon Jin Choi, Nayoung Kim
Gastric cancer is associated with high morbidity and mortality rates worldwide. Identifying individuals at high risk is important for surveillance and prevention of gastric cancer. Having first-degree relatives diagnosed with gastric cancer is a strong and consistent risk factor for gastric cancer, but the pathogenic mechanisms behind this familial aggregation are unclear. Against this background, we reviewed the risk factors for gastric cancer in those with a first-degree relative with gastric cancer, and the possible causes for familial clustering of gastric cancer including bacterial factors, inherited genetic susceptibility, environmental factors or a combination thereof...
November 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27806511/predictive-factors-of-survival-for-upper-gastrointestinal-cancers-in-iranian-population
#17
Ali Zargar, Aliakbar Hajaghamohammadi, Somayeh Ahmadi Gooraji
BACKGROUND: Upper gastrointestinal cancers (esophageal and gastric cancers) are among the most common cancers with high mortality and low survival rate. This study aimed to determine the predictive factors of survival for patients with upper gastrointestinal cancers in Iranian population. METHODS: In this study, 122 patients with upper gastrointestinal cancers diagnosed from 2007 to 2009 were included, who were referred to the only center of endoscopy in the northwest of Qazvin province...
July 19, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27804306/regression-of-gastric-intestinal-metaplasia-after-the-eradication-of-helicobacter-pylori-infection-in-a-hospital-in-mexico
#18
Jaime Alberto Sánchez Cuén, Ana Bertha Irineo Cabrales, Gregorio Bernal Magaña, Felipe Peraza Garay
BACKGROUND: Intestinal metaplasia is a precursor lesion of gastric cancer. Infection by Helicobacter pylori is the principal cause of metaplasia. While evidence of the regression of metaplasia after treatment to eradicate this infection has been demonstrated, controversy remains with regard to this subject. OBJECTIVE: The objective of this study was to determine the frequency of the regression of gastric intestinal metaplasia one year after the eradication of Helicobacter pylori...
December 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27803736/the-location-of-obstruction-predicts-stent-occlusion-in-malignant-gastric-outlet-obstruction
#19
Douglas Grunwald, Jonah Cohen, Anthony Bartley, Jennifer Sheridan, Ram Chuttani, Mandeep S Sawhney, Douglas K Pleskow, Tyler M Berzin, Meir Mizrahi
BACKGROUND: Gastric outlet obstruction (GOO) can occur with locally invasive or metastatic cancer involving the upper gastrointestinal tract at the pylorus or the duodenum. Endoscopic management with self-expanding metal stents (SEMSs) is often the preferred palliative approach. Stent occlusion is a common reason for failure and reintervention. We set out to determine whether the location of the malignant obstruction is associated with the angulation of the stent and can predict stent occlusion...
November 2016: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/27797257/diagnostic-power-of-blood-parameters-as-screening-markers-in-gastric-cancer-patients
#20
Lukasz Pietrzyk, Zbigniew Plewa, Marta Denisow-Pietrzyk, Remigiusz Zebrowski, Kamil Torres
BACKGROUND: Gastric cancer (GC) is the fifth most common cancer worldwide. Since development is usually asymptomatic, it is generally diagnosed at an advanced stage. The value of screening in patients with nonspecific symptoms for GC is controversial. AIM: The study aimed to evaluate whether hematological parameters (platelet count (PC), mean platelet volume (MPV), MPV/PC ratio, red blood cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR)) are useful markers to differentiate between gastric cancer patients and healthy individuals...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
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