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https://www.readbyqxmd.com/read/29222739/effects-of-two-aerobic-exercise-training-protocols-on-parameters-of-oxidative-stress-in-the-blood-and-liver-of-obese-rats
#1
Daniela Delwing-de Lima, Ariene Sampaio Souza Farias Ulbricht, Carla Werlang-Coelho, Débora Delwing-Dal Magro, Victor Hugo Antonio Joaquim, Eloise Mariani Salamaia, Silvana Rodrigues de Quevedo, Larissa Desordi
We evaluated the effects of moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT) protocols on the alterations in oxidative stress parameters caused by a high-fat diet (HFD), in the blood and liver of rats. The HFD enhanced thiobarbituric acid reactive substances (TBA-RS) and protein carbonyl content, while reducing total sulfhydryl content and catalase (CAT) and glutathione peroxidase (GSH-Px) activities in the blood. Both training protocols prevented an increase in TBA-RS and protein carbonyl content, and prevented a reduction in CAT...
December 8, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/29220207/mr-imaging-of-muscle-trauma-anatomy-biomechanics-pathophysiology-and-imaging-appearance
#2
Dyan V Flores, Catalina Mejía Gómez, Mauricio Estrada-Castrillón, Edward Smitaman, Mini N Pathria
Muscle is an important component of the muscle-tendon-bone unit, driving skeletal motion through contractions that alter the length of the muscle. The muscle and myotendinous junction (MTJ) are most commonly injured in the young adult, as a result of indirect mechanisms such as overuse or stretching, direct impact (penetrating or nonpenetrating), or dysfunction of the supporting connective tissues. Magnetic resonance (MR) imaging is widely used for assessment of muscle injuries. This review illustrates the MR imaging appearance of a broad spectrum of acute, subacute, and chronic traumatic lesions of muscle, highlighting the pathophysiology, biomechanics, and anatomic considerations underlying these lesions...
December 8, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29217633/stress-echocardiography-in-patients-with-native-valvular-heart-disease
#3
REVIEW
Patrizio Lancellotti, Raluca Dulgheru, Yun Yun Go, Tadafumi Sugimoto, Stella Marchetta, Cécile Oury, Madalina Garbi
Valve stress echocardiography (VSE) can be performed as exercise stress echocardiography (ESE) or dobutamine stress echocardiography (DSE) depending on the patient's clinical status, severity and type of valve disease. ESE combines exercise testing with two-dimensional grey scale and Doppler echocardiography during exercise. Thus, it provides objective assessment of symptomatic status (exercise test), as well as exercise-induced changes of a series of echocardiographic parameters (different depending on the valve disease type), which yield prognostic information in individual patients and help in a better treatment planning...
December 7, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29215907/chemotherapy-and-cognitive-impairment-an-animal-model-approach
#4
Gordon Winocur
A substantial number of cancer survivors who undergo chemotherapy report cognitive disturbances that severely limit daily function (chemobrain). Despite supportive neuropsychological evidence, there is controversy over whether cognitive impairment is caused by the chemotherapy or is the result of potentially confounding factors that include the disease itself, age, and psychological stress. Our research program, conducted on rodents, has confirmed that a range of cognitive processes, mediated in particular by hippocampal and prefrontal brain regions, are affected by anticancer drugs in combination with tumor development and that many of the effects are long lasting...
December 2017: Canadian Journal of Experimental Psychology, Revue Canadienne de Psychologie Expérimentale
https://www.readbyqxmd.com/read/29215751/proteomic-response-of-the-rat-liver-in-differential-swimming-modes
#5
Liang Chen, Yanhua Yang, Yiting Wang, Lipeng Qiu, Hengchuan Xia, Aiai Wang, Hailong Liu, Hongfei Shi, Keping Chen
Moderate exercise helps improve competition results, providing a balanced muscle tone and biochemical activity, whereas excessive training disrupts the balance between training and recovery, causes harm to the organism, and leads to overtraining syndrome (OTS). To explore the mechanisms of different protein expressions during training and acquisition of immunity, we used proteomic analyses to investigate the differences of liver-protein expressions between two swimming modes. Sprague-Dawley rats were randomly divided into control (CT), fatigue training (FT), and exhaustive training (ET) groups, and liver tissues from each group were subjected to two-dimensional electrophoresis (2DE)...
December 7, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/29215144/physiological-coherence-in-healthy-volunteers-during-laboratory-induced-stress-and-controlled-breathing
#6
Elisa Mejía-Mejía, Robinson Torres, Diana Restrepo
Physiological coherence has been related with a general sense of well-being and improvements in health and physical, social, and cognitive performance. The aim of this study was to evaluate the relationship between acute stress, controlled breathing, and physiological coherence, and the degree of body systems synchronization during a coherence-generation exercise. Thirty-four university employees were evaluated during a 20-min test consisting of four stages of 5-min duration each, during which basal measurements were obtained (Stage 1), acute stress was induced using validated mental stressors (Stroop test and mental arithmetic task, during Stage 2 and 3, respectively), and coherence states were generated using a controlled breathing technique (Stage 4)...
December 7, 2017: Psychophysiology
https://www.readbyqxmd.com/read/29212347/oxidative-stress-a-unifying-mechanism-for-cell-damage-induced-by-noise-water-pipe-smoking-and-emotional-stress-therapeutic-strategies-targeting-redox-imbalance
#7
Saeid Golbidi, Huige Li, Ismail Laher
SIGNIFICANCE: Modern technologies have eased our lives but these conveniences can impact our lifestyles in destructive ways. Noise pollution, mental stresses, and smoking (as a stress-relieving solution) are some environmental hazards which affect our well-being and health care budgets. Scrutinizing their pathophysiology could lead to solutions to reduce their harmful effects. Recent advances: Oxidative stress plays an important role in initiating local and systemic inflammation following noise pollution, mental stress, and smoking...
December 6, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29211694/prevention-of-bladder-cancer-incidence-and-recurrence-nutrition-and-lifestyle
#8
Christian D Fankhauser, Hugh Mostafid
PURPOSE OF REVIEW: We review the influence of nutrition and lifestyle on bladder cancer incidence and recurrence and summarize food items, diets and lifestyle practices that physicians may wish to prioritize for discussion with their patients. RECENT FINDINGS: Recent study results suggest an association between bladder cancer incidence and several food items including meat, fruit, vegetables, milk products and oil. Micronutrient deficiency is associated with bladder cancer risk; however, it remains unclear if micronutrient supplementation can modify bladder cancer incidence...
January 2018: Current Opinion in Urology
https://www.readbyqxmd.com/read/29210764/deriving-information-requirements-for-a-smart-nursing-system-for-intensive-care-units
#9
Kunal Khanade, Farzan Sasangohar, Steven C Sutherland, Karen E Alexander
The workplace environment for intensive care nursing is highly stressful, with long working hours and a dynamic workload that may induce fatigue. The resulting stress and fatigue may reduce nurses' efficiency and may contribute to medical errors. A smart wearable system is being designed to help nurses who experience high levels of stress and fatigue at work. This article documents the systematic process of deriving information requirements from 2 focus groups conducted separately with nurses and nurse managers working in various Southeastern Texas hospitals...
January 2018: Critical Care Nursing Quarterly
https://www.readbyqxmd.com/read/29207396/instrumentalization-of-eating-improves-weight-loss-maintenance-in-obesity
#10
Bodil Just Christensen, Eva Winning Iepsen, Julie Lundgren, Lotte Holm, Sten Madsbad, Jens Juul Holst, Signe Sørensen Torekov
AIM: The purpose of this study was to identify psychosocial determinants for maintaining weight loss. METHODS: 42 obese individuals who achieved a 12% weight loss before entering a 52-week weight maintenance program were interviewed qualitatively. Psychosocial factors related to weight loss maintenance were identified in two contrasting groups: weight reducers and weight regainers. Groups were defined by health-relevant weight maintenance (additional weight loss > 3% at week 52, n = 9 versus weight gain > 3%, at week 52, n = 20)...
December 6, 2017: Obesity Facts
https://www.readbyqxmd.com/read/29206761/skeletal-muscle-mitochondrial-function-is-determined-by-burn-severity-sex-and-sepsis-and-is-associated-with-glucose-metabolism-and-functional-capacity-in-burned-children
#11
Victoria G Rontoyanni, Ioannis Malagaris, David N Herndon, Eric Rivas, Karel D Capek, Anahi D Delgadillo, Nisha Bhattarai, Armando Elizondo, Charles D Voigt, Celeste C Finnerty, Oscar E Suman, Craig Porter
BACKGROUND: Restoring normal mitochondrial function represents a new target for strategies aimed at mitigating the stress response to severe burn trauma and hastening recovery. Our objective was to investigate the determinants of skeletal muscle mitochondrial respiratory capacity and function and its association with glucose metabolism and functional capacity in burned children. METHODS: Data from burned children enrolled in the placebo arm of an ongoing prospective clinical trial were analyzed...
December 4, 2017: Shock
https://www.readbyqxmd.com/read/29205021/health-mind-in-a-health-brain
#12
Jyrki Korkeila
The last few years have seen an increase in the research of psychic well-being and positive mental health. A positive point of view refers not only to pleasure but also to the ability to act in a constructive manner in challenging situations, and effectively regulate negative feelings and stress. Although a positive state of mind is often a passing experience, it can also be developed. Analogously, effective methods tested in a controlled manner have been established for the development of positive capabilities...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29204111/stereological-study-on-the-positive-effect-of-running-exercise-on-the-capillaries-in-the-hippocampus-in-a-depression-model
#13
Linmu Chen, Chunni Zhou, Chuanxue Tan, Feifei Wang, Yuan Gao, Chunxia Huang, Yi Zhang, Lin Jiang, Yong Tang
Running exercise is an effective method to improve depressive symptoms when combined with drugs. However, the underlying mechanisms are not fully clear. Cerebral blood flow perfusion in depressed patients is significantly lower in the hippocampus. Physical activity can achieve cerebrovascular benefits. The purpose of this study was to evaluate the impacts of running exercise on capillaries in the hippocampal CA1 and dentate gyrus (DG) regions. The chronic unpredictable stress (CUS) depression model was used in this study...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/29203714/exercise-heat-shock-proteins-and-insulin-resistance
#14
REVIEW
Ashley E Archer, Alex T Von Schulze, Paige C Geiger
Best known as chaperones, heat shock proteins (HSPs) also have roles in cell signalling and regulation of metabolism. Rodent studies demonstrate that heat treatment, transgenic overexpression and pharmacological induction of HSP72 prevent high-fat diet-induced glucose intolerance and skeletal muscle insulin resistance. Overexpression of skeletal muscle HSP72 in mice has been shown to increase endurance running capacity nearly twofold and increase mitochondrial content by 50%. A positive correlation between HSP72 mRNA expression and mitochondrial enzyme activity has been observed in human skeletal muscle, and HSP72 expression is markedly decreased in skeletal muscle of insulin resistant and type 2 diabetic patients...
January 19, 2018: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/29203458/evaluating-in-car-movements-in-the-design-of-mindful-commute-interventions-exploratory-study
#15
Pablo Enrique Paredes, Nur Al-Huda Hamdan, Dav Clark, Carrie Cai, Wendy Ju, James A Landay
BACKGROUND: The daily commute could be a right moment to teach drivers to use movement or breath towards improving their mental health. Long commutes, the relevance of transitioning from home to work, and vice versa and the privacy of commuting by car make the commute an ideal scenario and time to perform mindful exercises safely. Whereas driving safety is paramount, mindful exercises might help commuters decrease their daily stress while staying alert. Increasing vehicle automation may present new opportunities but also new challenges...
December 4, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29203160/myocardial-strain-may-predict-exercise-tolerance-in-patients-with-reduced-and-mid-range-ejection-fraction
#16
Elias Tsougos, George Angelidis, Elias Gialafos, Chara Tzavara, Vaios Tzifos, Ioannis Tsougos, Panagiotis Georgoulias
BACKGROUND: Conventional echocardiographic parameters, such as rest ejection fraction, perform poorly regarding the prediction of exercise tolerance in heart failure. The aim of the present study was to evaluate the contribution of hemodynamic instability in the observed lower functional capacity, investigating the role of left ventricular strain for the prediction of stress test duration in obese hypertensive patients with reduced ejection fraction. METHODS: Sixty-one patients with reduced ejection fraction underwent treadmill exercise echocardiography...
December 1, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29202762/myocyte-membrane-and-microdomain-modifications-in-diabetes-determinants-of-ischemic-tolerance-and-cardioprotection
#17
REVIEW
Jake Russell, Eugene F Du Toit, Jason N Peart, Hemal H Patel, John P Headrick
Cardiovascular disease, predominantly ischemic heart disease (IHD), is the leading cause of death in diabetes mellitus (DM). In addition to eliciting cardiomyopathy, DM induces a 'wicked triumvirate': (i) increasing the risk and incidence of IHD and myocardial ischemia; (ii) decreasing myocardial tolerance to ischemia-reperfusion (I-R) injury; and (iii) inhibiting or eliminating responses to cardioprotective stimuli. Changes in ischemic tolerance and cardioprotective signaling may contribute to substantially higher mortality and morbidity following ischemic insult in DM patients...
December 4, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29200984/mouth-rinsing-with-a-carbohydrate-solution-attenuates-exercise-induced-decline-in-executive-function
#18
Kana Konishi, Tetsuya Kimura, Atsushi Yuhaku, Toshiyuki Kurihara, Masahiro Fujimoto, Takafumi Hamaoka, Kiyoshi Sanada
Background: A decline in executive function could have a negative influence on the control of actions in dynamic situations, such as sports activities. Mouth rinsing with a carbohydrate solution could serve as an effective treatment for preserving the executive function in exercise. The purpose of this study was to examine the effects of mouth rinsing with a carbohydrate solution on executive function after sustained moderately high-intensity exercise. Methods: Eight young healthy participants completed 65 min of running at 75% V̇O2max with two mouth-rinsing conditions: with a carbohydrate solution (CHO) or with water (CON)...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29200906/effects-of-intermittent-ladder-climbing-exercise-training-on-mitochondrial-biogenesis-and-endoplasmic-reticulum-stress-of-the-cardiac-muscle-in-obese-middle-aged-rats
#19
Kijin Kim, Nayoung Ahn, Suryun Jung, Solee Park
The aim of this study is to investigate the effects of intermittent ladder-climbing exercise training on mitochondrial biogenesis and ER stress of the cardiac muscle in high fat diet-induced obese middle-aged rats. We induced obesity over 6 weeks of period in 40 male Sprague-Dawley rats around 50 weeks old, and were randomly divided into four experimental groups: chow, HFD, exercise+HFD, and exercise+chow. The exercising groups underwent high-intensity intermittent training using a ladder-climbing and weight exercise 3 days/week for a total of 8 weeks...
November 2017: Korean Journal of Physiology & Pharmacology
https://www.readbyqxmd.com/read/29200899/effects-of-exercise-on-obesity-induced-mitochondrial-dysfunction-in-skeletal-muscle
#20
REVIEW
Jun-Won Heo, Mi-Hyun No, Dong-Ho Park, Ju-Hee Kang, Dae Yun Seo, Jin Han, P Darrell Neufer, Hyo-Bum Kwak
Obesity is known to induce inhibition of glucose uptake, reduction of lipid metabolism, and progressive loss of skeletal muscle function, which are all associated with mitochondrial dysfunction in skeletal muscle. Mitochondria are dynamic organelles that regulate cellular metabolism and bioenergetics, including ATP production via oxidative phosphorylation. Due to these critical roles of mitochondria, mitochondrial dysfunction results in various diseases such as obesity and type 2 diabetes. Obesity is associated with impairment of mitochondrial function (e...
November 2017: Korean Journal of Physiology & Pharmacology
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