keyword
https://read.qxmd.com/read/38520071/in-situ-construction-of-interface-with-photothermal-and-mutual-catalytic-effect-for-efficient-solar-driven-reversible-hydrogen-storage-of-mgh-2
#1
JOURNAL ARTICLE
Xuechun Hu, Xiaowei Chen, Xiaoyue Zhang, Yang Meng, Guanglin Xia, Xuebin Yu, Dalin Sun, Fang Fang
Hydrogen storage in MgH2 is an ideal solution for realizing the safe storage of hydrogen. High operating temperature, however, is required for hydrogen storage of MgH2 induced by high thermodynamic stability and kinetic barrier. Herein, flower-like microspheres uniformly constructed by N-doped TiO2 nanosheets coated with TiN nanoparticles are fabricated to integrate the light absorber and thermo-chemical catalysts at a nanometer scale for driving hydrogen storage of MgH2 using solar energy. N-doped TiO2 is in situ transformed into TiNx Oy and Ti/TiH2 uniformly distributed inside of TiN matrix during cycling, in which TiN and Ti/TiHx pairs serve as light absorbers that exhibit strong localized surface plasmon resonance effect with full-spectrum light absorbance capability...
March 22, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38512500/boosting-hydrogen-storage-performance-of-mgh-2-by-oxygen-vacancy-rich-h-v-2-o-5-nanosheet-as-an-excited-h-pump
#2
JOURNAL ARTICLE
Li Ren, Yinghui Li, Zi Li, Xi Lin, Chong Lu, Wenjiang Ding, Jianxin Zou
MgH2 is a promising high-capacity solid-state hydrogen storage material, while its application is greatly hindered by the high desorption temperature and sluggish kinetics. Herein, intertwined 2D oxygen vacancy-rich V2 O5 nanosheets (H-V2 O5 ) are specifically designed and used as catalysts to improve the hydrogen storage properties of MgH2 . The as-prepared MgH2 -H-V2 O5 composites exhibit low desorption temperatures (Tonset  = 185 °C) with a hydrogen capacity of 6.54 wt%, fast kinetics (Ea  = 84...
March 21, 2024: Nano-Micro Letters
https://read.qxmd.com/read/38498436/single-atom-ni-supported-on-tio-2-for-catalyzing-hydrogen-storage-in-mgh-2
#3
JOURNAL ARTICLE
Jiyue Zhang, Wenda Wang, Xiaowei Chen, Jinlong Jin, Xiaojun Yan, Jianmei Huang
As an efficient and clean energy carrier, hydrogen is expected to play a key role in future energy systems. However, hydrogen-storage technology must be safe with a high hydrogen-storage density, which is difficult to achieve. MgH2 is a promising solid-state hydrogen-storage material owing to its large hydrogen-storage capacity (7.6 wt %) and excellent reversibility, but its large-scale utilization is restricted by slow hydrogen-desorption kinetics. Although catalysts can improve the hydrogen-storage kinetics of MgH2 , they reduce the hydrogen-storage capacity...
March 18, 2024: Journal of the American Chemical Society
https://read.qxmd.com/read/38445357/pharmacokinetic-study-of-multicomponent-in-hong-hua-xiao-yao-tablet
#4
JOURNAL ARTICLE
Xiaofeng Li, Leyi Huang, Junping Xiao, Xuemei Zhang
Hong-Hua-Xiao-Yao tablet (HHXYT) is attracting attention increasingly because of its use in treatment of mammary gland hyperplasia (MGH) and menopausal syndrome. However, its pharmacokinetics remains unclear. This study developed a sensitive and rapid method for simultaneous determination of 10 compounds of HHXYT in rat plasma by liquid chromatography-tandem mass spectrometry and to compare the pharmacokinetics of these compounds in MGH rats and sham operated rats. The linearity, accuracy, precision, stability and matrix effect were within acceptable ranges...
March 6, 2024: Biomedical Chromatography: BMC
https://read.qxmd.com/read/38416582/mgh-2-mg-bh-4-2-core-shell-like-nanostructures-synthesis-hydrolysis-performance-and-promotion-mechanism
#5
JOURNAL ARTICLE
Yongyang Zhu, Liming Zeng, Daifeng Wu, Shun Wang, Qing Zhou, Renheng Tang, Gary Chi-Pong Tsui, Zheng-Long Xu, Xu-Sheng Yang, Kangcheung Chan
The hydrolysis of hydrides, represented by MgH2 , delivers substantial capacity and presents an appealing prospect for an on-site hydrogen supply. However, the sluggish hydrolysis kinetics and low hydrogen yield of MgH2 caused by the formation of a passivation Mg(OH)2 layer hinder its practical application. Herein, we present a dual strategy encompassing microstructural design and compounding, leading to the successful synthesis of a core-shell-like nanostructured MgH2 @Mg(BH4 )2 composite, which demonstrates excellent hydrolysis performance...
February 28, 2024: Nano Letters
https://read.qxmd.com/read/38383031/predictors-of-clinical-deterioration-and-intensive-care-unit-admission-in-trauma-patients-transferred-from-northern-quebec-to-a-level-1-trauma-centre-a-retrospective-cohort-study
#6
JOURNAL ARTICLE
Jeongyoon Moon, Tarek Razek, Jeremy Grushka, Dan Deckelbaum, Nathalie Boulanger, Larry Watt, Kosar Khwaja, Paola Fata, Katherine McKendy, Atif Jastaniah, Evan G Wong
BACKGROUND: Trauma care in Nunavik, Quebec, is highly challenging. Geographic distances and delays in transport can translate into precarious patient transfers to tertiary trauma care centres. The objective of this study was to identify predictors of clinical deterioration during transport and eventual intensive care unit (ICU) admission for trauma patients transferred from Nunavik to a tertiary trauma care centre. METHODS: This is a retrospective cohort study using the Montreal General Hospital (MGH) trauma registry...
2024: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://read.qxmd.com/read/38370801/sars-cov-2-infection-elucidates-unique-features-of-pregnancy-specific-immunity
#7
Dong Sun Oh, Eunha Kim, Guangqing Lu, Rachelly Normand, Lydia L Shook, Amanda Lyall, Olyvia Jasset, Stepan Demidkin, Emily Gilbert, Joon Kim, Babatunde Akinwunmi, Jessica Tantivit, Alice Tirard, Benjamin Y Arnold, Kamil Slowikowski, Marcia B Goldberg, Michael R Filbin, Nir Hacohen, Long H Nguyen, Andrew T Chan, Xu G Yu, Jonathan Z Li, Lael Yonker, Alessio Fasano, Roy H Perlis, Ofer Pasternak, Kathryn J Gray, Gloria B Choi, David A Drew, Pritha Sen, Alexandra-Chloé Villani, Andrea G Edlow, Jun R Huh
Pregnancy is a risk factor for increased severity of SARS-CoV-2 and other respiratory infections. The mechanisms underlying this risk have not been well-established, partly due to a limited understanding of how pregnancy shapes immune responses. To gain insight into the role of pregnancy in modulating immune responses at steady state and upon perturbation, we collected peripheral blood mononuclear cells (PBMC), plasma, and stool from 226 women, including 152 pregnant individuals (n = 96 with SARS-CoV-2 infection and n = 56 healthy controls) and 74 non-pregnant women (n = 55 with SARS-CoV-2 and n = 19 healthy controls)...
February 7, 2024: medRxiv
https://read.qxmd.com/read/38347983/documentation-of-international-classification-of-headache-disorders-criteria-in-patient-medical-records-a-retrospective-cohort-analysis
#8
JOURNAL ARTICLE
Michelle Pershing, Omkar Hirekhan, Azfar Syed, John O Elliott, Jonathan Toot
OBJECTIVE: To determine headache diagnosis and treatment patterns in the outpatient setting, focusing on documentation of the International Classification of Headache Disorders (ICHD) criteria. DESIGN, SETTING, AND PARTICIPANTS: Retrospective cohort data were collected from electronic medical records of adults aged 18-35 who presented to resident-staffed family medicine outpatient clinics in the Midwest, USA, for a new or worsening headache between 2015 and 2016...
January 2024: Curēus
https://read.qxmd.com/read/38340708/hbv-reactivation-and-clinical-resolution-in-an-isolated-anti-hbc-positive-patient-during-immune-checkpoint-inhibition
#9
JOURNAL ARTICLE
Lukas S Baumert, Angela R Shih, Raymond T Chung
BACKGROUND: Immune checkpoint inhibitor (ICI)-related liver injury is a growing concern as ICIs are increasingly used in cancer treatment regimens. Interestingly, ICIs have exhibited antiviral effects among patients with chronic hepatitis B virus (HBV). However, the underlying mechanisms remain unclear, and clinical data on patients with previous HBV infection/exposure and isolated anti-HBV core antibodies (IAHBcs) are lacking. METHODS: We report a case illustrating the dual effects of ICIs in a patient experiencing panlobular hepatitis and concurrent HBV reactivation...
February 9, 2024: Med
https://read.qxmd.com/read/38323851/the-silk-collaborative-a-multidisciplinary-approach-to-serious-illness-communication-for-patients-with-liver-failure-and-acute-kidney-injury
#10
JOURNAL ARTICLE
Danielle L Saly, Andrew S Allegretti, Nneka N Ufere
No abstract text is available yet for this article.
February 7, 2024: Kidney360
https://read.qxmd.com/read/38309310/microbiome-analysis-reveals-the-differences-in-gut-fungal-community-between-dutch-warmblood-and-mongolian-horses
#11
JOURNAL ARTICLE
Yanfang Lan, Yunyun Hu, Yingfang Guo, Farah Ali, Nouman Amjad, Quanli Ouyang, Mikhlid H Almutairi, Dongjing Wang
Similar to gut bacterial community, gut fungal community are also an important part of the gut microbiota and play crucial roles in host immune regulation and metabolism. However, most studies have focused on the gut bacterial community, and research on the gut fungal community has been limited. Dutch Warmblood (DWH) and Mongolian horses (MGH) are important equine breeds, but little research has been done on their gut fungal community. Here, we assessed differences in gut fungal community between two horse species...
February 1, 2024: Microbial Pathogenesis
https://read.qxmd.com/read/38300188/let-d-optimization-verification-with-an-soi-microdosimeter
#12
JOURNAL ARTICLE
V A Pan, L T Tran, T Madden, B Clasie, H Kooy, A B Rosenfeld, N Depauw
PURPOSE: A first of its kind experimental verification of dose-averaged linear energy transfer (LETd ) optimized treatment plans for proton therapy has been carried out using a silicon-on-insulator microdosimeter at the Massachusetts General Hospital (MGH), Boston, USA. METHODS AND MATERIALS: Three clinical treatment plans of a typical ependymoma structure set were designed using the standard clinical approach, the proposed protocol approach, and a one-field approach...
January 31, 2024: International Journal of Radiation Oncology, Biology, Physics
https://read.qxmd.com/read/38297990/development-of-an-electronic-decision-aid-tool-to-facilitate-mainstream-genetic-testing-in-ovarian-cancer-patients
#13
JOURNAL ARTICLE
Kristen M Shannon, Devanshi Patel, Jessica M Jonas, Erica L Blouch, Stephanie R Hicks, Mackenzie Wooters, Meredith Seidel, Carly F Grant, Margaret M Emmet, Daniel C Chung, Karen Sepucha
BACKGROUND: Multigene panel testing is an important component of cancer treatment plans and risk assessment, but there are many different panel options and choosing the most appropriate panel can be challenging for health care providers and patients. Electronic tools have been proposed to help patients make informed decisions about which gene panel to choose by considering their preferences and priorities. MATERIALS AND METHODS: An electronic decision aid (DA) tool was developed in line with the International Patient Decision Aids Standards collaboration...
January 31, 2024: Oncologist
https://read.qxmd.com/read/38286196/immunosuppressant-drug-monitor-a-non-invasive-device-to-measure-tacrolimus-level-in-the-saliva-of-transplanted-patients
#14
JOURNAL ARTICLE
Laura Charlès, Elise Lupon, Tia Sheth, Olivier Camuzard, Alexandre G Lellouch, Chetan Shende, Stuart Farquharson, Kassem Safa, Curtis L Cetrulo
Solid organ and vascularized composite allograft transplantation are pivotal in enhancing both life expectancy and quality of life. However, the significant risk of donor tissue rejection requires lifelong immunosuppressive therapy. Tacrolimus, a common component of immunosuppressive regimens, offers effectiveness in preventing organ rejection but poses challenges due to its narrow therapeutic window and toxicity, making it essential to carefully monitor its concentration. Tacrolimus trough levels are currently measured in blood, requiring frequent blood draws from patients, and results are available after 3 to 6 hours...
January 27, 2024: International Journal of Pharmaceutics
https://read.qxmd.com/read/38272345/near-infrared-photoimmunotherapy-targeting-nectin-4-in-a-preclinical-model-of-bladder-cancer
#15
JOURNAL ARTICLE
Hiroshi Fukushima, Seiichiro Takao, Aki Furusawa, Vladimir Valera Romero, Sandeep Gurram, Takuya Kato, Shuhei Okuyama, Makoto Kano, Peter L Choyke, Hisataka Kobayashi
Enfortumab vedotin (EV), an antibody-drug conjugate (ADC) that targets Nectin-4, has shown promising results in the treatment of bladder cancer. However, multiple resistance mechanisms that are unique to ADCs limit the therapeutic potential of EV in clinical practice. Here, we developed and tested a Nectin-4-targeted near-infrared photoimmunotherapy (NIR-PIT) that utilizes the same target as EV but utilizes a distinct cytotoxic and immunotherapeutic pathway in preclinical models of bladder cancer. NIR-PIT was effective in vitro against luminal subtype human bladder cancer cell lines (RT4, RT112, MGH-U3, SW780, and HT1376-luc), but not against other subtype cell lines (UMUC3 and T24)...
January 23, 2024: Cancer Letters
https://read.qxmd.com/read/38270953/evaluating-the-implementation-of-the-connect-for-health-pediatric-weight-management-program
#16
JOURNAL ARTICLE
Meg Simione, Holly M Frost, Haley Farrar-Muir, Man Luo, Jazmin Granadeño, Carlos Torres, Alexy Arauz Boudreau, Jennifer Moreland, Jessica Wallace, Jackie Young, John Orav, Kerry Sease, Simon J Hambidge, Elsie M Taveras
IMPORTANCE: Adoption of primary care interventions to reduce childhood obesity is limited. Progress in reducing obesity prevalence and eliminating disparities can be achieved by implementing effective childhood obesity management interventions in primary care settings. OBJECTIVE: To examine the extent to which implementation strategies supported the uptake of research evidence and implementation of the Connect for Health pediatric weight management program. DESIGN, SETTING, AND PARTICIPANTS: This quality improvement study took place at 3 geographically and demographically diverse health care organizations with substantially high numbers of children living in low-income communities in Denver, Colorado; Boston, Massachusetts; and Greenville, South Carolina, from November 2019 to April 2022...
January 2, 2024: JAMA Network Open
https://read.qxmd.com/read/38240304/global-minimum-and-a-heap-of-low-lying-isomers-with-planar-tetracoordinate-carbon-in-the-cal-3-mgh-2-system
#17
JOURNAL ARTICLE
Abdul Hamid Malhan, Krishnan Thirumoorthy
A global minimum and a heap of low-lying isomers with planar tetracoordinate carbon (ptC) are identified in the CAl3 MgH2 - system by computational quantum chemical investigations. The nature of the chemical bonding in the global minimum ptC isomer is examined using the conceptual quantum chemical tools. The atoms in molecule (AIM) analysis reveals that the global minimum isomer possesses a ptC geometry. Additionally, the adaptive natural density partitioning (AdNDP), electron localization function (ELF), and nucleus-independent chemical shifts (NICS) analysis corroborate the presence of delocalization in the ptC isomer...
January 19, 2024: Physical Chemistry Chemical Physics: PCCP
https://read.qxmd.com/read/38200767/evaluation-of-the-effectiveness-of-medical-grade-honey-and-hypericum-perforatum-ointment-on-second-intention-healing-of-full-thickness-skin-wounds-in-cats
#18
JOURNAL ARTICLE
Kyriakos Chatzimisios, Vassiliki Tsioli, Georgia D Brellou, Emmanouela P Apostolopoulou, Vasileia Angelou, Emmanouil D Pratsinakis, Niels A J Cremers, Lysimachos G Papazoglou
This study aimed to determine the effects of two topical treatments on second-intention wound healing in cats. Eight 2 × 2 cm full-thickness wounds were created, four on each side of the dorsal midline of eight laboratory cats, to receive either medical-grade honey ointment (MGH) and its control (HC), or Hypericum-based ointment (HP) and its control (HPC). MGH or HP ointment was applied to four wounds on the same side, while the remaining four were used as controls, chosen at random. Planimetry, laser Doppler flowmetry, daily physical examinations, and histologic examinations on days 0, 7, 14, and 25 were used to assess the healing of wounds...
December 21, 2023: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38196148/integration-of-the-cancer-cell-secretome-and-transcriptome-reveals-potential-noninvasive-diagnostic-markers-for-bladder-cancer
#19
JOURNAL ARTICLE
Yi-Ting Chen, Wei-Ju Tu, Zong-Han Ye, Chih-Ching Wu, Shir-Hwa Ueng, Kai-Jie Yu, Chien-Lun Chen, Pei-Hua Peng, Jau-Song Yu, Ying-Hsu Chang
PURPOSE: Bladder cancer (BLCA) is a major cancer of the genitourinary system. Although cystoscopy is the standard protocol for diagnosing BLCA clinically, this procedure is invasive and expensive. Several urine-based markers for BLCA have been identified and investigated, but none has shown sufficient sensitivity and specificity. These observations underscore the importance of discovering novel BLCA biomarkers and developing a noninvasive method for detection of BLCA. Exploring the cancer secretome is a good starting point for the development of noninvasive biomarkers for cancer diagnosis...
January 9, 2024: Proteomics. Clinical Applications
https://read.qxmd.com/read/38194080/impulsivity-in-adolescent-girls-diagnosed-with-trichotillomania-an-evaluation-of-clinical-and-neuropsychological-characteristics
#20
JOURNAL ARTICLE
Hande Günal Okumuş, Devrim Akdemir, Rahime Duygu Temeltürk, Makbule Esen Öksüzoğlu
The aim of this study is to compare the clinical and neuropsychological features of impulsivity in adolescent girls with trichotillomania (TTM) and healthy controls, and to assess the relationships between the severity of TTM and the impulsivity/concomitant symptoms of anxiety and depression. The study sample consisted of 43 adolescent girls who were 12 to 18 years old. The Kiddie-Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version DSM-5 (K-SADS-PL) was administered to the adolescents and their parents...
January 9, 2024: European Child & Adolescent Psychiatry
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