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https://www.readbyqxmd.com/read/29331910/review-of-synthetic-human-faeces-and-faecal-sludge-for-sanitation-and-wastewater-research
#1
REVIEW
Roni Penn, Barbara J Ward, Linda Strande, Max Maurer
Investigations involving human faeces and faecal sludge are of great importance for urban sanitation, such as operation and maintenance of sewer systems, or implementation of faecal sludge management. However, working with real faecal matter is difficult as it not only involves working with a pathogenic, malodorous material but also individual faeces and faecal sludge samples are highly variable, making it difficult to execute repeatable experiments. Synthetic faeces and faecal sludge can provide consistently reproducible substrate and alleviate these challenges...
December 30, 2017: Water Research
https://www.readbyqxmd.com/read/29331595/the-interaction-between-neurocognitive-functioning-subthreshold-psychotic-symptoms-and-pharmacotherapy-in-22q11-2-deletion-syndrome-a-longitudinal-comparative-study
#2
R Weinberger, O Weisman, Y Guri, T Harel, A Weizman, D Gothelf
BACKGROUND: The 22q11.2 deletion syndrome (22q11DS) is the most common genetic syndrome associated with schizophrenia. The goal of this study was to evaluate longitudinally the interaction between neurocognitive functioning, the presence of subthreshold psychotic symptoms (SPS) and conversion to psychosis in individuals with 22q11DS. In addition, we attempted to identify the specific neurocognitive domains that predict the longitudinal evolution of positive and negative SPS, as well as the effect of psychiatric medications on 22q11DS psychiatric and cognitive developmental trajectories...
December 8, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29329697/ageing-perceptions-and-non-adherence-to-aromatase-inhibitors-among-breast-cancer-survivors
#3
Moriah J Brier, Dianne L Chambless, Jinbo Chen, Jun J Mao
PURPOSE: Aromatase inhibitors (AIs) are a potentially life-saving treatment for breast cancer survivors, yet poor adherence to treatment is a prevalent problem. A common adverse effect of AI treatment is arthralgia, which is identified by survivors as a major reason for treatment discontinuation. Women who experience arthralgia on AIs often report feeling they have aged rapidly while on the treatment. In the present study, we examined whether arthralgia-associated ageing perceptions predicted non-adherence...
January 9, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29327166/loneliness-in-psychosis-a-systematic-review
#4
REVIEW
Michelle H Lim, John F M Gleeson, Mario Alvarez-Jimenez, David L Penn
PURPOSE: The aim of the review is to understand the relationships between loneliness and related psychological and social factors in individuals with psychosis. Loneliness is poorly understood in people with psychosis. Given the myriad of social challenges facing individuals with psychosis, these findings can inform psychosocial interventions that specifically target loneliness in this vulnerable group. METHODS: We adhered to the PRISMA guidelines and systematically reviewed empirical studies that measured loneliness either as a main outcome or as an associated variable in individuals with psychosis...
January 11, 2018: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29316948/traditional-uses-of-medicinal-plants-practiced-by-the-indigenous-communities-at-mohmand-agency-fata-pakistan
#5
Muhammad Abdul Aziz, Muhammad Adnan, Amir Hasan Khan, Abdelaaty Abdelaziz Shahat, Mansour S Al-Said, Riaz Ullah
BACKGROUND: Plant-derived products have an imperative biological role against certain pathogenic organisms and were considered to be a major source of modern drugs. Rural people residing in developing countries are relying on traditional herbal medical system due to their strong believe and minimum access to allopathic medicines. Hence, ethnomedicinal knowledge is useful for the maintenance of community's based approaches under this medical system. Present study was carried out in an unexplored remote tribal area of Pakistan to investigate and document the existing ethnomedicinal knowledge on local flora...
January 9, 2018: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/29303459/multimodal-treatment-approach-in-a-patient-with-multiple-intracranial-myxomatous-aneurysms
#6
David L Penn, Arianna B Lanpher, Jennifer M Klein, Harry P W Kozakewich, Kristopher T Kahle, Edward R Smith, Darren B Orbach
The most common primary cardiac tumor is myxoma, typically originating in the left atrium. Emboli to the central nervous system can cause cerebral infarction or, rarely, seed tumor growth within vessel walls, causing myxomatous aneurysms. Fewer than 60 myxomatous aneurysms have been reported, including 2 cases in children. Here, the authors describe 2 different growing myxomatous aneurysms in a child successfully managed using a combined multidisciplinary approach. A 12-year-old boy developed a sudden headache, diplopia, gait instability, and speech difficulty...
January 5, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29301935/-inhibition-of-histone-h3k27-demethylase-selectively-modulates-inflammatory-phenotypes-of-natural-killer-cells
#7
Adam Cribbs, Edward S Hookway, Graham Wells, Morten Lindow, Susanna Obad, Henrik Oerum, Rab K Prinjha, Nick Athanasou, Aneka Sowman, Martin Philpott, Henry Penn, Kalle Soderstrom, Marc Feldmann, Udo Oppermann
Natural killer (NK) cells are innate lymphocytes, important in immune surveillance and elimination of stressed, transformed, or virus-infected cells. They critically shape the inflammatory cytokine environment to orchestrate interactions of cells of the innate and adaptive immune systems. Some studies have reported that NK cell activation and cytokine secretion are controlled epigenetically, but have yielded only limited insight into the mechanisms. Using chemical screening with small-molecule inhibitors of chromatin methylation and acetylation, further validated by knockdown approaches, we here identified Jumonji-type histone H3K27 demethylases as key regulators of cytokine production in human NK cell subsets...
January 4, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29301700/3d-brain-tumor-localization-and-parameter-estimation-using-thermographic-approach-on-gpu
#8
Abdelmajid Bousselham, Omar Bouattane, Mohamed Youssfi, Abdelhadi Raihani
The aim of this paper is to present a GPU parallel algorithm for brain tumor detection to estimate its size and location from surface temperature distribution obtained by thermography. The normal brain tissue is modeled as a rectangular cube including spherical tumor. The temperature distribution is calculated using forward three dimensional Pennes bioheat transfer equation, it's solved using massively parallel Finite Difference Method (FDM) and implemented on Graphics Processing Unit (GPU). Genetic Algorithm (GA) was used to solve the inverse problem and estimate the tumor size and location by minimizing an objective function involving measured temperature on the surface to those obtained by numerical simulation...
January 2018: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29301699/two-dimensional-closed-form-model-for-temperature-in-living-tissues-for-hyperthermia-treatments
#9
Jaideep Dutta, Balaram Kundu
This research article determines an exact analytical expression for 2-D thermal field in single layer living tissues under a therapeutic condition by means of Fourier and non-Fourier heat transfer approaches. An actual spatially dependent initial condition has been adopted to analyze the heat propagation in tissues. The exact analytical determination for this actual initial condition for temperature may be difficult. However, in this study, an approximate analytical method has newly been established for an appropriate initial condition...
January 2018: Journal of Thermal Biology
https://www.readbyqxmd.com/read/29301008/psychometric-evaluation-of-the-patient-reported-outcomes-measurement-information-system-promis-nicotine-dependence-item-bank-for-use-with-electronic-cigarettes
#10
Meghan Morean, Suchitra Krishnan-Sarin, Steve Sussman, Jonathan Foulds, Howard Fishbein, Rachel Grana, Stephanie S O'Malley
Introduction: Psychometrically sound measures of e-cigarette dependence are lacking. Methods: We modified the PROMIS Nicotine Dependence Item Banks for use with e-cigarettes and evaluated the psychometrics of the 22-, 8- and 4-item adapted versions. 1009 adults who reported using e-cigarettes at least weekly completed an anonymous survey in Summer 2016 (50.2% male, 77.1% White, mean age 35.81 [10.71], 66.4% daily e-cigarette users, 72.6% current cigarette smokers)...
January 2, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29289175/effects-of-transients-in-ligo-suspensions-on-searches-for-gravitational-waves
#11
M Walker, T D Abbott, S M Aston, G González, D M Macleod, J McIver, B P Abbott, R Abbott, C Adams, R X Adhikari, S B Anderson, A Ananyeva, S Appert, K Arai, S W Ballmer, D Barker, B Barr, L Barsotti, J Bartlett, I Bartos, J C Batch, A S Bell, J Betzwieser, G Billingsley, J Birch, S Biscans, C Biwer, C D Blair, R Bork, A F Brooks, G Ciani, F Clara, S T Countryman, M J Cowart, D C Coyne, A Cumming, L Cunningham, K Danzmann, C F Da Silva Costa, E J Daw, D DeBra, R T DeRosa, R DeSalvo, K L Dooley, S Doravari, J C Driggers, S E Dwyer, A Effler, T Etzel, M Evans, T M Evans, M Factourovich, H Fair, A Fernández Galiana, R P Fisher, P Fritschel, V V Frolov, P Fulda, M Fyffe, J A Giaime, K D Giardina, E Goetz, R Goetz, S Gras, C Gray, H Grote, K E Gushwa, E K Gustafson, R Gustafson, E D Hall, G Hammond, J Hanks, J Hanson, T Hardwick, G M Harry, M C Heintze, A W Heptonstall, J Hough, K Izumi, R Jones, S Kandhasamy, S Karki, M Kasprzack, S Kaufer, K Kawabe, N Kijbunchoo, E J King, P J King, J S Kissel, W Z Korth, G Kuehn, M Landry, B Lantz, N A Lockerbie, M Lormand, A P Lundgren, M MacInnis, S Márka, Z Márka, A S Markosyan, E Maros, I W Martin, D V Martynov, K Mason, T J Massinger, F Matichard, N Mavalvala, R McCarthy, D E McClelland, S McCormick, G McIntyre, G Mendell, E L Merilh, P M Meyers, J Miller, R Mittleman, G Moreno, G Mueller, A Mullavey, J Munch, L K Nuttall, J Oberling, M Oliver, P Oppermann, Richard J Oram, B O'Reilly, D J Ottaway, H Overmier, J R Palamos, H R Paris, W Parker, A Pele, S Penn, M Phelps, V Pierro, I Pinto, M Principe, L G Prokhorov, O Puncken, V Quetschke, E A Quintero, F J Raab, H Radkins, P Raffai, S Reid, D H Reitze, N A Robertson, J G Rollins, V J Roma, J H Romie, S Rowan, K Ryan, T Sadecki, E J Sanchez, V Sandberg, R L Savage, R M S Schofield, D Sellers, D A Shaddock, T J Shaffer, B Shapiro, P Shawhan, D H Shoemaker, D Sigg, B J J Slagmolen, B Smith, J R Smith, B Sorazu, A Staley, K A Strain, D B Tanner, R Taylor, M Thomas, P Thomas, K A Thorne, E Thrane, C I Torrie, G Traylor, D Tuyenbayev, G Vajente, G Valdes, A A van Veggel, A Vecchio, P J Veitch, K Venkateswara, T Vo, C Vorvick, R L Ward, J Warner, B Weaver, R Weiss, P Weßels, B Willke, C C Wipf, J Worden, G Wu, H Yamamoto, C C Yancey, Hang Yu, Haocun Yu, L Zhang, M E Zucker, J Zweizig
This paper presents an analysis of the transient behavior of the Advanced LIGO (Laser Interferometer Gravitational-wave Observatory) suspensions used to seismically isolate the optics. We have characterized the transients in the longitudinal motion of the quadruple suspensions during Advanced LIGO's first observing run. Propagation of transients between stages is consistent with modeled transfer functions, such that transient motion originating at the top of the suspension chain is significantly reduced in amplitude at the test mass...
December 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29287663/the-could-and-the-should-of-reconstructing-severe-hind-foot-injuries
#12
EDITORIAL
Jowan G Penn-Barwell, Philippa M Bennett, Andrew C Gray
No abstract text is available yet for this article.
December 26, 2017: Injury
https://www.readbyqxmd.com/read/29287588/relation-between-duration-of-the-prodromal-phase-and-renal-damage-in-anca-associated-vasculitis
#13
Eline Houben, Stefanie L Groenland, Joost W van der Heijden, Alexandre E Voskuyl, Hiëronymus J Doodeman, Erik L Penne
BACKGROUND: In ANCA-associated vasculitis the acute phase of the disease is often preceded by prodromal symptoms. The aim of the present study was to analyze the relation between the duration of the prodromal phase and renal damage. METHODS: Patients with ANCA-associated vasculitis and renal involvement from a retrospective single-center cohort were divided into two equal groups based on the duration of the prodromal phase. The prodromal phase was defined as the time between first vasculitis related symptoms and the date of diagnosis...
December 29, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29287237/a-novel-approach-of-substitution-therapy-with-inhalation-of-essential-oil-for-the-reduction-of-inhalant-craving-a-double-blinded-randomized-controlled-trial
#14
Rasmon Kalayasiri, Wanjaree Maneesang, Michael Maes
Inhalants, which are neurotoxic central nervous system (CNS) suppressants, are frequently abused by young adults. Unlike other CNS depressants, including alcohol and opiates, no treatment is currently approved for inhalant dependence. In this report, a novel approach of substitution treatment for inhalant addiction was explored in a double-blinded, randomized, controlled crossover design to examine the effects of inhalation of essential oil and perfume on the reduction of cue-induced craving for inhalant in thirty-four Thai males with inhalant dependence...
December 11, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29280026/management-of-non-functioning-pituitary-adenomas-surgery
#15
REVIEW
David L Penn, William T Burke, Edward R Laws
Non-functional pituitary adenomas (NFPAs) are benign tumors of the pituitary gland that do not over-secrete hormonal products, therefore, they are generally detected through symptoms of mass effect, including headache, vision loss, or hypopituitarism. There are multiple pathological subtypes of NFPAs, such as null cell adenomas, silent gonadotrophs, silent somatotrophs, silent corticotrophs, and silent subtype 3, all of which can be classified based on immunohistochemical studies and electron microscopy. Despite these numerous pathological subtypes, surgical resection remains the first-line treatment for NFPAs...
December 26, 2017: Pituitary
https://www.readbyqxmd.com/read/29275814/changing-the-paradigm-of-defining-detecting-and-diagnosing-nec-perspectives-on-bell-s-stages-and-biomarkers-for-nec
#16
Sheila M Gephart, Phillip V Gordon, Alexander H Penn, Katherine E Gregory, Jonathan R Swanson, Akhil Maheshwari, Karl Sylvester
Better means to diagnose and define necrotizing enterocolitis are needed to guide clinical practice and research. Adequacy of Bell's staging system for clinical practice and clarity of cases used in NEC clinical datasets has been a topic of controversy for some time. This article provides reasons why a better global definition for NEC is needed and offers a simple alternative bedside definition for preterm NEC called the "Two out of Three" rule. Some argue that biomarkers may fill knowledge gaps and provide greater precision in defining relevant features of a clinical disease like NEC...
February 2018: Seminars in Pediatric Surgery
https://www.readbyqxmd.com/read/29261012/the-association-of-anxiety-depression-and-worry-symptoms-on-cognitive-performance-in-older-adults
#17
Alyssa de Vito, Matthew Calamia, Steven Greening, Scott Roye
Emerging research suggests that a relationship exists between the cognitive aspects of anxiety (e.g. worry) and cognitive decline in older adults. The current study examined the association between anxiety, depressive, and worry symptoms on cognitive performance. Participants were 156 older adults enrolled in the Nathan Kline Institute-Rockland Sample Study (NKI-RS).  Hierarchical linear regression analysis was used to determine the unique associations of anxiety, depressive, and worry symptoms on cognitive performance as measured by the Penn Computerized Neurocognitive Battery (Penn CNB), the Delis-Kaplan Executive Function System (D-KEFS), and the Rey Auditory Verbal Learning Test (RAVLT)...
December 20, 2017: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/29251055/validation-of-a-multivariate-clinical-prediction-model-for-the-diagnosis-of-mild-stroke-transient-ischemic-attack-in-physician-first-contact-patient-settings
#18
Maximilian B Bibok, Andrew M Penn, Mary L Lesperance, Kristine Votova, Robert Balshaw
We validate our previously developed (DOI: 10.1101/089227) clinical prediction rule for diagnosing transient ischemic attack on the basis of presenting clinical symptoms and compare its performance with the ABCD2 score in first-contact patient settings. Two independent and prospectively collected patient validation cohorts were used: (a) referral cohort-prospectively referred emergency department and general practitioner patients ( N = 877); and (b) SpecTRA cohort-participants recruited as part of the SpecTRA biomarker project ( N = 545)...
December 1, 2017: Health Informatics Journal
https://www.readbyqxmd.com/read/29249958/unlocking-neurocognitive-substrates-of-late-life-affective-symptoms-using-the-research-domain-criteria-worry-is-an-essential-dimension
#19
Sherry A Beaudreau, Nathan C Hantke, Nehjla Mashal, Christine E Gould, Victor W Henderson, Ruth O'Hara
While investigations have sought to identify the distinct and shared contributions of anxiety and depression to neurocognitive processes in late life, less is known regarding the further contribution of worry, a unique and critical dimension of affective dysregulation. Capturing the full range of symptoms, as inspired by the NIH Research Domain Criteria (RDoC), may provide finer-grained information on inter-relationships among worry, anxiety and depression on neurocognitive processing in later life. The objective of this study was to determine if the dimensional trait of worry intensifies known negative associations of dimensional measures of anxiety and depressive symptoms with neurocognitive processes, specifically cognitive control and memory processes...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29244137/severe-traumatic-brain-injury
#20
David L Penn, John H Chi, Mark R Proctor
No abstract text is available yet for this article.
January 1, 2018: Neurosurgery
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