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Q Mahmood, M Hassan, N A Noor
The structural, magnetic and optical characteristics of Zn1-x TM x S/Se (TM  =  Mn, Fe, Co, Ni and x  =  6.25%) have been investigated through the full-potential linearized augmented plane wave method within the framework of density functional theory. The optimized structures have been used to calculate the ferromagnetic and the antiferromagnetic ground-state energies. The stability of the ferromagnetic phase has been confirmed from the formation and the cohesive energies. The Heisenberg model is used to elucidate the Curie temperature (T c) of these alloys...
October 19, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Stephen J Nicholas, Steven J Lee, Michael J Mullaney, Timothy F Tyler, Takumi Fukunaga, Christopher D Johnson, Malachy P McHugh
BACKGROUND: The functional benefits of double-row (DR) versus single-row (SR) rotator cuff repair are not clearly established. PURPOSE: To examine the effect of DR versus SR rotator cuff repair on functional outcomes and strength recovery in patients with full-thickness tears. STUDY DESIGN: Randomized controlled trial; Level of evidence, 2. METHODS: Forty-nine patients were randomized to DR or SR repairs; 36 patients (13 women, 23 men; mean age, 62 ± 7 years; 20 SR, 16 DR) were assessed at a mean 2...
October 2016: Orthopaedic Journal of Sports Medicine
Eline Houben, Willem A Bax, Bastiaan van Dam, Walentina A T Slieker, Gideon Verhave, Fenneke C P Frerichs, Izhar C van Eijk, Wim G Boersma, Guido T M de Kuyper, Erik L Penne
Currently no validated diagnostic system for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is available. Therefore, diagnosing AAV is often challenging. We aimed to identify factors that lead to a clinical diagnosis AAV in ANCA positive patients in a teaching hospital in The Netherlands.In this study, all patients that tested positive for ANCA proteinase 3 (PR3) and/or myeloperoxidase (MPO) between 2005 and 2015 were analysed. Patients with a clinical diagnosis of AAV were compared with patients without a clinical diagnosis of AAV...
October 2016: Medicine (Baltimore)
Zheng Fang
This article describes two publicly available data sources: the new generation of Penn World Table ( and the BP Statistical Review of World Energy ( which can be used to examine the role of human capital in the energy-growth nexus across countries. The critical human capital measure across countries is for the first time made available in the Penn World Table 8.0 and it enables empirical researchers to conduct cross-country analysis involving human capital much easily than ever before...
December 2016: Data in Brief
Payman Zamani, Benjamin French, Jeffrey A Brandimarto, Paschalis-Thomas Doulias, Ali Javaheri, Julio A Chirinos, Kenneth B Margulies, Raymond R Townsend, Nancy K Sweitzer, James C Fang, Harry Ischiropoulos, Thomas P Cappola
Endothelial function may be deranged in heart failure with preserved ejection fraction (HFpEF). Serum NO-derived metabolites (NOm) might provide a biochemical surrogate of endothelial function in patients with heart failure (HF). We measured serum NOm in 415 participants in the Penn HF Study. Participants with HFpEF (n = 82) and those whose EF had recovered (Recovered-HF, n = 125) were matched 1:1 to heart failure with reduced ejection fraction (HFrEF) participants based on age, gender, race, tobacco use, and eGFR...
September 15, 2016: American Journal of Cardiology
Laura Oakley, Nicole Penn, Maria Pipi, Eugene Oteng-Ntim, Pat Doyle
OBJECTIVE: The objective of this study was to investigate whether moderately increased maternal age is associated with obstetric and neonatal outcome in a contemporary population, and to consider the possible role of co-morbidities in explaining any increased risk. STUDY DESIGN: Secondary analysis of routinely collected data from a large maternity unit in London, UK. Data were available on 51,225 singleton deliveries (≥22 weeks) occurring to women aged ≥20 between 2004 and 2012...
2016: PloS One
Danielle Cornacchio, Amy E Pinkham, David L Penn, Philip D Harvey
Patients with severe mental illnesses manifest substantial deficits in self-assessment of the abilities that impact everyday functioning. This study compares patients with schizophrenia to healthy individuals on their social cognitive performance, their assessment of that performance, and the convergence between performance and indicators of effort in solving tasks. Patients with schizophrenia (n=57) and healthy controls (HC; n=47) completed the Bell-Lysaker Emotion Recognition Test (BLERT), a psychometrically sound assessment of emotion recognition...
September 29, 2016: Schizophrenia Research
Lori S Hoggard, LaBarron K Hill
BACKGROUND: African Americans experience more problematic and disordered sleep than White Americans. Racial discrimination has been implicated in this disparity. However, the mechanisms by which discrimination disrupts sleep are unclear. It has been theorized that Perseverative Cognition (PC), characterized by recurrent patterns of reflective (i.e., rumination) and anticipatory (i.e., worry) negative thinking about personally relevant stressors, may reflect the functional mechanism linking discrimination to sleep...
October 3, 2016: Behavioral Sleep Medicine
Henrik Odéen, Scott Almquist, Joshua de Bever, Douglas A Christensen, Dennis L Parker
BACKGROUND: A major challenge in using magnetic resonance temperature imaging (MRTI) to monitor focused ultrasound (FUS) applications is achieving high spatio-temporal resolution over a large field of view (FOV). This is important to accurately monitor all ultrasound (US) power depositions. Magnetic resonance (MR) subsampling in conjunction with thermal model-based reconstruction of the MRTI utilizing Pennes bioheat transfer equation (PBTE) is one promising approach. The thermal properties used in the thermal model are often estimated from a pre-treatment, low-power sonication...
2016: Journal of Therapeutic Ultrasound
Jonathan A Anson, Elbert J Mets, Sonia J Vaida, Tonya S King, Tim Ochoa, Vitaly Gordin
STUDY OBJECTIVE: Back injuries are a highly reported category of occupational injury in the health care setting. The daily clinical activities of an anesthesia provider, including lifting, pushing stretchers, transferring patients, and bending for procedures, are risk factors for developing low back pain. The purpose of this study is to investigate the prevalence of work related low back pain in anesthesia providers. DESIGN/SETTING: We conducted a cross-sectional survey study of anesthesia providers at an academic institution...
November 2016: Journal of Clinical Anesthesia
Jo Hall, Stephen Kellett, Raul Berrios, Manreesh Kaur Bains, Shonagh Scott
OBJECTIVE: Generalized anxiety disorder (GAD) is a common disorder in older adults producing functional impairment, and psychotherapy is the preferred treatment option. Meta-analytic methods sought to determine the efficacy of outpatient cognitive behavioral therapy (CBT) with respect to the hallmark feature of GAD-uncontrolled and excessive worry. In order to optimize clinical applicability, variables associated with GAD treatment outcomes were also examined. METHODS: Systematic search of relevant databases and iterative searches of references from articles retrieved...
November 2016: American Journal of Geriatric Psychiatry
Rogério Bonassi Machado, Luciano Melo Pompei, Mariangela Badalotti, Rui Ferriani, Achilles M Cruz, Eliana Nahas, Hugo Maia
OBJECTIVES: The aim of the study was to assess the efficacy for menstrual-related symptoms of an extended flexible regimen of an oral contraceptive pill containing 20 μg ethinylestradiol and 3 mg drospirenone in comparison with a 24/4 d cyclical regimen of the same formulation. METHODS: This randomised, non-inferiority, open-label, multicentre study was conducted in women aged 18-39 years. Their menstrual-related symptoms were assessed using the Penn Daily Symptom Rating (DSR17)...
September 29, 2016: European Journal of Contraception & Reproductive Health Care
Louis Goffe, Wendy Wrieden, Linda Penn, Frances Hillier-Brown, Amelia A Lake, Vera Araujo-Soares, Carolyn Summerbell, Martin White, Ashley J Adamson, Jean Adams
OBJECTIVES: To determine if the amount of salt delivered by standard salt shakers commonly used in English independent takeaways varies between those with five and 17 holes; and to determine if any differences are robust to variations in: the amount of salt in the shaker, the length of time spent shaking, and the person serving. DESIGN: Four laboratory experiments comparing the amount of salt delivered by shakers. Independent variables considered were: type of shaker used (five or 17 holes), amount of salt in the shaker before shaking commences (shaker full, half full or nearly empty), time spent shaking (3s, 5s or 10s), and individual serving...
2016: PloS One
Charles M Olbert, David L Penn, Steven P Reise, William P Horan, Robert S Kern, Junghee Lee, Michael F Green
Attachment has recently been proposed as a key developmental construct in psychosis, in particular with respect to interpersonal functioning and social cognition. The current study examined the latent structure of the self-report Psychosis Attachment Measure (PAM) and its relationship to lower-level perceptual and higher-order inferential social cognitive processes. The PAM was administered to 138 psychiatrically stable outpatients with schizophrenia alongside a battery of symptom, social cognitive, and functional measures...
September 15, 2016: Psychiatry Research
Jordan Gaines, Alexandros N Vgontzas, Julio Fernandez-Mendoza, Susan L Calhoun, Fan He, Duanping Liao, Marjorie D Sawyer, Edward O Bixler
Only a handful of studies, primarily in clinical samples, have reported an association between obesity, inflammation, and obstructive sleep apnea (OSA) in children and adolescents. No studies, however, have examined the pathogenetic link between visceral adiposity, systemic inflammation, and incident OSA in a large general population sample using objective measures of sleep and body fat. Adolescents (n=392; mean age 17.0±2.2y, 54.0% male) from the Penn State Child Cohort (PSCC) underwent 9-hour overnight polysomnography; a DXA scan to assess body fat distribution; and a single fasting blood draw for the assessment of plasma interleukin-6 (IL-6), IL-6 soluble receptor (IL-6 sR), tumor necrosis factor alpha (TNFα), tumor necrosis factor receptor 1A (TNFR1), C-reactive protein (CRP), leptin, and adiponectin levels via ELISA...
September 20, 2016: American Journal of Physiology. Endocrinology and Metabolism
Jagmohan Singh, Ettickan Boopathi, Sankar Addya, Benjamin Phillips, Isidore Rigoutsos, Raymond B Penn, Satish Rattan
A comprehensive -omic, computational, and physiological approach was employed to examine the (previously unexplored) role of microRNAs (miRNAs) as regulators of IAS smooth muscle contractile phenotype and basal tone. MicroRNA profiling, genome wide expression, validation and network analyses were employed to assess changes in mRNA and miRNA expression in IAS smooth muscles from young vs. aging rats. Multiple miRNAs, including rno-miR-1, rno-miR-340-5p, rno-miR-185, rno-miR-199a-3p, rno-miR-200c, rno-miR-200b, rno-miR-31, rno-miR-133a and rno-miR-206 were found to be up-regulated in aging IAS...
September 15, 2016: American Journal of Physiology. Gastrointestinal and Liver Physiology
Helmet Karim, Dana Larisa Tudorascu, Howard Aizenstein, Sarah Walker, Rachel Good, Carmen Andreescu
OBJECTIVE: Generalized anxiety disorder (GAD) in older adults is associated with persistent deficits in emotion reactivity (ER) and regulation, yet the neural basis of these deficits has not been explored. This study focuses on the neural basis of ER deficits in late-life GAD and the association with cerebrovascular burden. METHODS: Twenty elderly nonanxious participants and 17 late-life GAD participants were included. The faces-shapes functional magnetic resonance imaging task was used to assess ER; the Hamilton Anxiety Rating Scale and the Penn State Worry Questionnaire to measure global anxiety and worry, respectively; linear regression models to examine the association between ER and global anxiety severity and between ER and worry severity; and mediation analysis to explore the effect of ER on the relationship between global anxiety/worry severity and cerebrovascular burden...
November 2016: American Journal of Geriatric Psychiatry
Anna U Morgan, David T Grande, Tamala Carter, Judith A Long, Shreya Kangovi
Community-engaged researchers who work with low-income communities can be reliant on grant funding. We use the illustrative case of the Penn Center for Community Health Workers (PCCHW) to describe a step-by-step framework for achieving financial sustainability for community-engaged research interventions. PCCHW began as a small grant-funded research project but followed an 8-step framework to engage both low-income patients and funders, determine outcomes, and calculate return on investment. PCCHW is now fully funded by Penn Medicine and delivers the Individualized Management for Patient-Centered Targets (IMPaCT) community health worker intervention to 2000 patients annually...
November 2016: American Journal of Public Health
Jennifer H Strehlau, Melissa S Stemig, R Lee Penn, William A Arnold
Nitroaromatic compounds are groundwater pollutants that can be degraded through reactions with Fe(II) adsorbed on iron oxide nanoparticles, although little is known about the evolving reactivity of the minerals with continuous pollutant exposure. In this work, Fe(II)/goethite reactivity toward 4-chloronitrobenzene (4-ClNB) as a function of pH, organic matter presence, and reactant concentrations was explored using sequential-spike batch reactors. Reaction rate constants were smaller with lower pH, introduction of organic matter, and diluted reactant concentrations as compared to a reference condition...
October 4, 2016: Environmental Science & Technology
P Kumar, Dinesh Kumar, K N Rai
This paper theoretically investigates the thermal behavior in a living biological tissue under various coordinate systems and different non-Fourier boundary conditions with the dual-phase-lag bioheat transfer model during thermal therapy. The properties of Legendre wavelets together with the finite difference scheme are used to find an approximate analytical solution of the present problem. It has been observed that surrounding healthy tissues are less affected in second and third kind of boundary condition when applied along with spherical symmetric coordinate system...
November 2016: Mathematical Biosciences
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