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https://www.readbyqxmd.com/read/29338554/site-specific-evaluation-of-lymphatic-vessel-sclerosis-in-lower-limb-lymphedema-patients
#1
Makoto Mihara, Hisako Hara, Yoshihisa Kawakami, Han Peng Zhou, Shuichi Tange, Kazuki Kikuchi, Takuya Iida
BACKGROUND: Histological changes in the collecting lymphatics in patients with lymphedema are classified as Normal type, Ectasis type, Contraction type, and Sclerosis type (NECST) classification. In this study, we investigated the condition of the lymphatic vessels in different sites of the legs. PATIENTS AND METHODS: We prospectively investigated the lymphatic vessels of patients with lymphedema who underwent lymphaticovenous anastomosis (LVA) from August 8, 2014 to August 4, 2015 based on the NECST classification...
January 17, 2018: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/29327607/up-regulation-of-cav3-1-expression-in-sh-sy5y-cells-induced-by-lidocaine-hydrochloride
#2
Qin Gong, Xianjie Wen, Heng Li, Jian He, Yunhua Wang, Huiping Wu, Hanbing Wang, Xiaoping Wang
BACKGROUND: Neurotoxicity induced by the local anaesthetics has aroused concern. A previous study has shown that an overload of intracellular calcium was involved in the neurotoxic effect. Cav3.1 is one of the low-voltage-activated (LVA) calcium channels which play a key point to regulate the intracellular calcium ion level. This study aimed to investigate the changes of the Cav3.1 expression in the SH-SY5Y cells treated with lidocaine hydrochloride. METHODS: The SH-SY5Y cells were treated with different concentrations of lidocaine hydrochloride(1 mM, 5 mM and 10 mM, namely L1 group, L5 group and L10 group) and different exposure times (1 h,12 h and 24 h), respectively...
January 12, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29318381/-evaluation-of-the-medical-treatment-situation-of-the-visually-impaired-significant-differences-between-young-and-old
#3
M Oeverhaus, H Hirche, J Esser, A Eckstein, B Schaperdoth-Gerlings
BACKGROUND AND OBJECTIVE: Patients with irreversible visual impairment need individual visual rehabilitation to regain or improve reading ability and mobility. To analyze the prescription of low vision aids (LVA) and their relation to age, we performed a retrospective chart analysis of our specialized low vision outpatient clinic. METHODS: Patient charts of all patients who attended our low vision outpatient clinic from 2014-2016 were analyzed with respect to the diagnosis, visual acuity, magnification needs, age and prescribed or used LVA...
January 9, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29313561/relation-between-post-procedural-platelet-count-and-left-ventricular-aneurysm-in-patients-with-acute-anterior-st-elevated-myocardial-infarction-following-primary-percutaneous-coronary-intervention
#4
Zuoyan Wang, Lihui Ren, Na Liu, Jianjun Peng
BACKGROUND: Left ventricular aneurysm (LVA) relates to the worse prognosis of patients with myocardial infarction despite successful reperfusion treatment. There is no evidence of early detectable biomarkers to predict risk for the future development of LVA. The aim of our study was to investigate the possible predictive value of peri-procedural hematological parameters for the LVA. METHODS: A total of 281 patients with acute anterior ST-elevated myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PPCI) were enrolled...
January 9, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29288397/a-cadaveric-study-of-aortic-arch-variation-in-an-irish-population
#5
Aisling M O'Malley, Walid H El Kininy, Helina Debebe, Azreena B Burukan, Shane W Davy
AIM: The aim of this study is to investigate the incidence of variation in the branching pattern of aortic arch (AA) vessels in an Irish population. METHOD: A cadaveric study of 24 subjects was conducted. The vessels of the AA were identified, their branching patterns were noted and photographed and the following measurements were recorded: the angle of the AA to the coronal plane, the distance from the midline to the brachiocephalic trunk (BCT); the left common carotid artery (LCC) ; the left subclavian artery (LSC), the distance between the BCT and the right subclavian artery (RSC); the RSC and the right vertebral artery (RVA), and between the LSC and left vertebral artery (LVA)...
December 29, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29286964/lymphaticovenous-anastomoses-for-lymphedema-complicated-by-severe-lymphorrhea-following-resection-of-soft-tissue-sarcomas-of-the-adductor-compartment-a-report-of-two-cases
#6
Hiroshi Kobayashi, Takuya Iida, Takumi Yamamoto, Masachika Ikegami, Yusuke Shinoda, Sakae Tanaka, Hirotaka Kawano
CASE: Lymphedema and lymphorrhea are major causes of wound complications after the resection of soft-tissue sarcomas in the adductor compartment of the thigh. We report 2 cases of successful treatment of lymphedema and lymphorrhea, which had been refractory to nonoperative treatment, with use of lymphaticovenous anastomosis (LVA) and intraoperative indocyanine green lymphography after the resection of a sarcoma in the adductor compartment. CONCLUSION: These 2 cases highlight that LVA can be a useful and minimally invasive alternative to myocutaneous flaps for the treatment of wound complications caused by lymphedema and lymphorrhea after surgery for soft-tissue sarcomas in the adductor compartment of the thigh...
October 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29275886/the-extent-of-left-atrial-low-voltage-areas-included-in-pulmonary-vein-isolation-is-associated-with-freedom-from-recurrent-atrial-arrhythmia
#7
Dong Huang, Jing-Bo Li, Tarek Zghaib, Esra Gucuk Ipek, Muhammad Balouch, David D Spragg, Hiroshi Ashikaga, Harikrishna Tandri, Sunil K Sinha, Joseph E Marine, Ronald D Berger, Hugh Calkins, Saman Nazarian
BACKGROUND: The extent of left atrial (LA) baseline low-voltage areas (LVA-B), which may be a surrogate for fibrosis, is associated with recurrent atrial fibrillation (AF) after ablation. This study aimed to assess the relationship between the extent of LVA-B isolated by ablation (LVA-I) and AF recurrence. METHODS: The study cohort included 159 consecutive patients with drug-refractory AF who underwent an initial AF ablation with LA voltage mapping during sinus rhythm...
January 2018: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29272990/coronary-sinus-signal-amplitude-predicts-left-atrial-scarring
#8
Philipp Attanasio, Daniel Qaiyumi, Robert Röhle, Alexander Wutzler, Erdal Safak, Bogdan Muntean, Leif-Hendrik Boldt, Burkert Pieske, Wilhelm Haverkamp, Martin Huemer
BACKGROUND: Left atrial scarring is recognised as a critical component in the maintenance of atrial fibrillation and is associated with the failure of interventional treatment. Diminished bipolar voltage (LV) has been proposed as a useful tool for left atrial scar quantification. We hypothesised that, due to its anatomic location, signals on the coronary sinus catheter might be used to predict the amount of left atrial low voltage. METHODS AND RESULTS: A total of 124 patients (42% women, average age 66 ± 9 years) were included...
December 22, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/29177475/individually-tailored-vs-standardized-substrate-modification-during-radiofrequency-catheter-ablation-for-atrial-fibrillation-a-randomized-study
#9
Simon Kircher, Arash Arya, David Altmann, Sascha Rolf, Andreas Bollmann, Philipp Sommer, Nikolaos Dagres, Sergio Richter, Ole-A Breithardt, Borislav Dinov, Daniela Husser, Charlotte Eitel, Thomas Gaspar, Christopher Piorkowski, Gerhard Hindricks
Aims: This randomized single-centre study sought to compare the efficacy and safety of pulmonary vein isolation (PVI) plus voltage-guided ablation vs. PVI with or without linear ablation depending on the type of atrial fibrillation (AF). Methods and results: Overall, 124 ablation-naive patients with paroxysmal or persistent AF were randomized to PVI with (persistent AF) or without (paroxysmal AF) additional linear ablation (control group) vs. PVI plus ablation of low-voltage areas (LVAs) irrespective of AF type...
November 21, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29110936/right-versus-left-apical-transvenous-pacing-for-bradycardia-results-of-the-rivela-randomized-study
#10
Haran Burri, Hajo Müller, Richard Kobza, Christian Sticherling, Peter Ammann, Heiko Zerlik, Carine Stettler, Catherine Klersy, Frits Prinzen, Angelo Auricchio
AIMS: To compare cardiac function when pacing from the right or left ventricular apex in patients with preserved left ventricular systolic function, at 1-year follow-up. METHODS: Prospective, multicentre centre randomizing conventional right ventricular apical (RVA) versus left ventricular apical (LVA) pacing using a coronary sinus lead in patients requiring ventricular pacing for bradycardia. Follow-up was performed using 3D-echocardiography at 6 and 12 months...
October 27, 2017: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29100882/multi-site-lymphatic-venous-anastomosis-using-echography-to-detect-suitable-subcutaneous-vein-in-severe-lymphedema-patients
#11
Makoto Mihara, Hisako Hara, Yoshihisa Kawakami, Hang Peng Zhou, Shuichi Tange, Kazuki Kikuchi, Takuya Iida
BACKGROUND: The method of lymphatic venous anastomosis (LVA), including its indications or preoperative examinations, has not been established. The purpose of this study is to reveal the possible application of preoperative echography in surgical LVA outcome. METHODS: We performed a retrospective case-control study on patients with lower limb lymphedema who underwent LVA between August 15, 2013 and August 15, 2014. As a preoperative examination, we used venous echography to identify subcutaneous veins in the echo group, while we only used Accuvein visualizing system in the control group...
October 17, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29071967/-efficacy-of-modified-acupuncture-method-at-renying-st-9-for-patients-with-cervical-spondylosis-of-vertebral-artery-type-and-its-impact-on-velocity-of-cervical-blood-flow
#12
Xing-Hua Gui, Chao-Yang Ma, Lei Tang, Wen-Jun Wan, Yan-Fu Wang, Fen Xu, Shun-Yu Zhao
OBJECTIVE: To observe the clinical efficacy of modified acupuncture at Renying point (ST 9) for patients with cervical spondylosis of vertebral artery type and its influence on velocity of cervical blood flow. METHODS: Fifty-nine cases of vertebral artery type cervical spondylosis were randomly divided into control group (n=30) and treatment group (n=29). Both groups were acupunctured at ST 9, with routine acupuncture technique used in the control group and modified technique in the treatment group, respectively...
April 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29058780/effective-and-efficient-lymphaticovenular-anastomosis-using-preoperative-ultrasound-detection-technique-of-lymphatic-vessels-in-lower-extremity-lymphedema
#13
Akitatsu Hayashi, Nobuko Hayashi, Hidehiko Yoshimatsu, Takumi Yamamoto
BACKGROUND: Identification of functional lymphatic vessels and localization of lymphatic vessels are important for lymphaticovenular anastomosis (LVA). Indocyanine green (ICG) lymphography is useful for localization of superficial lymphatic vessels where dermal backflow is not observed, but not for lymphatic vessels in deep layer or where dermal backflow is observed. Ultrasound has been applied in LVA and is considered useful for localization of lymphatic vessels with ICG lymphography cannot be visualized...
October 23, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29038409/-total-arch-replacement-for-distal-arch-aneurysm-with-isolated-left-vertebral-artery-report-of-a-case
#14
Motonori Uchino, Masaru Yoshikai, Hisashi Sato, Jun Osaki
We herein present a case of distal aortic arch aneurysm with an isolated left vertebral artery(LVA). In surgery, after establishing cardiopulmonary bypass, the LVA was anastomosed to the left common carotid artery (LCCA) while under moderate hypothermia. Selective cerebral perfusion (SCP) was then initiated by inserting catheters into the brachiocephalic artery( BCA), the LCCA and the left subclavian artery (LSA). The aorta was transected between the BCA and the LCCA, and an open stent graft was deployed into the descending aorta during circulatory arrest...
October 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29027927/conotoxins-as-tools-to-understand-the-physiological-function-of-voltage-gated-calcium-cav-channels
#15
REVIEW
David Ramírez, Wendy Gonzalez, Rafael A Fissore, Ingrid Carvacho
Voltage-gated calcium (CaV) channels are widely expressed and are essential for the completion of multiple physiological processes. Close regulation of their activity by specific inhibitors and agonists become fundamental to understand their role in cellular homeostasis as well as in human tissues and organs. CaV channels are divided into two groups depending on the membrane potential required to activate them: High-voltage activated (HVA, CaV1.1-1.4; CaV2.1-2.3) and Low-voltage activated (LVA, CaV3.1-3.3)...
October 13, 2017: Marine Drugs
https://www.readbyqxmd.com/read/29016757/association-of-left-atrial-low-voltage-area-and-thromboembolic-risk-in-patients-with-atrial-fibrillation
#16
Patrick Müller, Hisaki Makimoto, Johannes W Dietrich, Franzsika Fochler, Karin Nentwich, Joachum Krug, David Duncker, Christian Blockhaus, Malte Kelm, Alexander Fürnkranz, Thomas Deneke, Philipp Halbfass
Aims: Atrial fibrillation (AF) is associated with thromboembolic events. Currently, the CHA2DS2-VASc score is recommended for thromboembolic risk stratification in non-valvular AF patients. However, recent data suggested a potential role of atrial remodelling on thromboembolism. This study aimed to assess the association between left atrial low-voltage area (LVA) and history of clinical manifest as well as subclinical silent cerebral ischaemia (SCI) in AF patients. Methods and results: Two-hundred patients [64 ± 10...
July 25, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28988444/usefulness-of-epicardial-impedance-evaluation-for-epicardial-mapping-and-determination-of-epicardial-ablation-site-for-ventricular-tachycardia-a-pilot-study
#17
Takeshi Kitamura, Seiji Fukamizu, Satoshi Miyazawa, Iwanari Kawamura, Rintaro Hojo, Yuya Aoyama, Mitsuhiro Nishizaki, Harumizu Sakurada, Masayasu Hiraoka
BACKGROUND: During epicardial mapping, determination of appropriate ablation sites in low voltage areas (LVA) is challenging because of large epicardial areas covered by adipose tissue. OBJECTIVE: To evaluate the impedance difference between epicardial fat and the epicardial LVA using multiple detector computed tomography (MDCT). METHODS: We enrolled patients who underwent ventricular tachycardia (VT) ablation via the epicardial approach after endocardial ablation failure...
October 8, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28972280/systematic-review-of-lymphovenous-anastomosis-lva-for-the-treatment-of-lymphedema
#18
REVIEW
Mario F Scaglioni, Duveken B Y Fontein, Michael Arvanitakis, Pietro Giovanoli
INTRODUCTION: Lymphedema is a chronic condition caused by the obstruction or impairment of lymphatic fluid transport resulting in irreversible skin fibrosis. Besides conservative therapy, surgical techniques for lymphedema including liposuction, lymphatico-lymphatic bypass, lymphovenous anastomosis (LVA), and vascularized lymph node transfer (VLNT) are options with increasing popularity in the recent past. In our review, we investigated the efficacy of LVA for the treatment of lymphedema...
October 3, 2017: Microsurgery
https://www.readbyqxmd.com/read/28952193/lymphatic-mapping-of-the-upper-limb-with-lymphedema-before-lymphatic-supermicrosurgery-by-mirroring-of-the-healthy-limb
#19
Stefano Gentileschi, Maria Servillo, Roberta Albanese, Francesca De Bonis, Girolamo Tartaglione, Marzia Salgarello
INTRODUCTION: Supermicrosurgical lymphatic-venous anastomosis (LVA) can improve limbs lymphedema. We describe a technique that we employ for preoperative lymphatic mapping of the upper limb (UL), when indocyanine green (ICG) lymphography shows only dermal backflow (DB) and no lymphatic vessel is detectable. PATIENTS AND METHODS: Sixteen patients undergoing LVA for unilateral UL lymphedema, showing "stardust" or "diffuse" DB pattern, were included. Demographic, clinical data, and limbs measurements were recorded...
September 27, 2017: Microsurgery
https://www.readbyqxmd.com/read/28894674/lymphedema-of-the-lower-extremities-due-to-refractory-malignant-lymphoma-treated-by-lymphaticovenous-anastomosis
#20
Naohiro Ishii, Marie Aoki, Kazuo Kishi
Lymphaticovenous anastomosis (LVA) is primarily performed for lymphedema of the lower extremities after surgical treatment of gynecologic cancer and lymphedema of the upper extremities after surgical resection of breast cancer; however, LVA for lymphedema due to malignant lymphoma has not been reported to date. We herein present a patient with severe lymphedema of the lower extremities due to refractory malignant lymphoma, which markedly improved with LVA. LVA could contribute to improve quality of life in patients with end-stage disease with lymphedema of the lower extremities due to refractory malignant lymphoma...
August 2017: Plastic and Reconstructive Surgery. Global Open
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