keyword
MENU ▼
Read by QxMD icon Read
search

cyclotron

keyword
https://www.readbyqxmd.com/read/28917103/isolation-of-a-2-picolinic-acid-assimilating-bacterium-and-its-proposed-degradation-pathway
#1
Chunli Zheng, Qiaorui Wang, Yanli Ning, Yurui Fan, Shanshan Feng, Chi He, Tian C Zhang, Zhenxing Shen
Burkholderia sp. ZD1, aerobically utilizes 2-picolinic acid as a source of carbon, nitrogen and energy, was isolated. ZD1 completely degraded 2-picolinic acid when the initial concentrations ranged from 25 to 300mg/L. Specific growth rate (μ) and specific consumption rate (q) increased continually in the concentration range of 25-100mg/L, and then declined. Based on the Haldane model and Andrew's model, μmax and qmax were calculated as 3.9 and 16.5h(-1), respectively. Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) was used to determine the main intermediates in the degradation pathway...
September 6, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28915744/communication-charge-transfer-dominates-over-proton-transfer-in-the-reaction-of-nitric-acid-with-gas-phase-hydrated-electrons
#2
Jozef Lengyel, Jakub Med, Petr Slavíček, Martin K Beyer
The reaction of HNO3 with hydrated electrons (H2O)n(-) (n = 35-65) in the gas phase was studied using Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry and ab initio molecular dynamics simulations. Kinetic analysis of the experimental data shows that OH(-)(H2O)m is formed primarily via a reaction of the hydrated electron with HNO3 inside the cluster, while proton transfer is not observed and NO3(-)(H2O)m is just a secondary product. The reaction enthalpy was determined using nanocalorimetry, revealing a quite exothermic charge transfer with -241 ± 69 kJ mol(-1)...
September 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28905088/new-horizons-in-cardiac-innervation-imaging-introduction-of-novel-18-f-labeled-pet-tracers
#3
Ryohei Kobayashi, Xinyu Chen, Rudolf A Werner, Constantin Lapa, Mehrbod S Javadi, Takahiro Higuchi
Cardiac sympathetic nervous activity can be uniquely visualized by non-invasive radionuclide imaging techniques due to the fast growing and widespread application of nuclear cardiology in the last few years. The norepinephrine analogue (123)I-meta-iodobenzylguanidine ((123)I-MIBG) is a single photon emission computed tomography (SPECT) tracer for the clinical implementation of sympathetic nervous imaging for both diagnosis and prognosis of heart failure. Meanwhile, positron emission tomography (PET) imaging has become increasingly attractive because of its higher spatial and temporal resolution compared to SPECT, which allows regional functional and dynamic kinetic analysis...
September 13, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28895554/anomalous-cyclotron-mass-dependence-on-the-magnetic-field-and-berry-s-phase-in-cd-sub-1-x-y-sub-zn-sub-x-sub-mn-sub-y-sub-sub-3-sub-as-sub-2-sub-solid-solutions
#4
Vasilii S Zakhvalinskii, Tatyana Nikulicheva, Erkki Lähderanta, Mikhail A Shakhov, Ekaterina Nikitovskaya, Sergey Taran
Shubnikov-de Haas (SdH) effect and magnetoresistance measurements of single crystals of diluted II-V magnetic semiconductors (Cd<sub>1-x-y</sub>Zn<sub>x</sub>Mn<sub>y</sub>)<sub>3</sub>As<sub>2</sub> (x + y = 0.4, y = 0.04 and 0.08) are investigated in the temperature range T = 4.2 ÷ 300 K and in transverse magnetic field B = 0 ÷ 25 T. The values of the cyclotron mass m<sub>c</sub>, the effective g-factor g*, and the Dingle temperature T<sub>D</sub> are defined...
September 12, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28894190/novel-detection-of-post-translational-modifications-in-human-monocyte-derived-dendritic-cells-after-chronic-alcohol-exposure-role-of-inflammation-regulator-h4k12ac
#5
Tiyash Parira, Gloria Figueroa, Alejandra Laverde, Gianna Casteleiro, Mario E Gomez Hernandez, Francisco Fernandez-Lima, Marisela Agudelo
Previous reports on epigenetic mechanisms involved in alcohol abuse have focus on hepatic and neuronal regions, leaving the immune system and specifically monocyte-derived dendritic cells (MDDCs) understudied. Our lab has previously shown histone deacetylases are modulated in cells derived from alcohol users and after in vitro acute alcohol treatment of human MDDCs. In the current study, we developed a novel screening tool using matrix assisted laser desorption ionization-fourier transform-ion cyclotron resonance mass spectrometry (MALDI-FT-ICR MS) and single cell imaging flow cytometry to detect post-translational modifications (PTMs) in human MDDCs due to chronic alcohol exposure...
September 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28888821/-11-c-bctc-radiosynthesis-and-in-vivo-binding-to-transient-receptor-potential-vanilloid-subfamily-member-1-trpv1-receptor-in-the-mouse-trigeminal-nerve
#6
Katsushi Kumata, Joji Yui, Yiding Zhang, Yusuke Kurihara, Masanao Ogawa, Wakana Mori, Masayuki Fujinaga, Ming-Rong Zhang
The purpose of this study was to synthesize a new positron emission tomography radiotracer, N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-[(11)C]carboxamide ([(11)C]BCTC, [(11)C]1), and assess its in vivo binding to the transient receptor potential vanilloid subfamily member 1 (TRPV1) receptor in mice. [(11)C]BCTC was synthesized by reacting the hydrochloride of 4-tertiarybutylaniline (2·HCl) with [(11)C]phosgene ([(11)C]COCl2) to give isocyanate [(11)C]4, followed by reaction with 4-(3-chloropyridin-2-yl)tetrahydropyrazine (3)...
September 1, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28886580/a-plasma-metabonomic-analysis-on-potential-biomarker-in-pyrexia-induced-by-three-methods-using-ultra-high-performance-liquid-chromatography-coupled-with-fourier-transform-ion-cyclotron-resonance-mass-spectrometry
#7
Ting Liu, Songhe Li, Xiumin Tian, Zhaoqin Li, Yue Cui, Fei Han, Yunli Zhao, Zhiguo Yu
Pyrexia usually is a systemic pathological process that can lead to metabolic disorders. Metabonomics as a powerful tool not only can reveal the pathological mechanisms, but also can give insight into the progression of pyrexia from another angle. Thus, an ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry (UHPLC-FT-ICR-MS) metabonomic approach was employed for the first time to investigate the plasma biochemical characteristics of pyrexia induced by three methods and to reveal subtle metabolic changes under the condition of pyrexia so as to explore its mechanism...
August 24, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28863634/correlation-electron-cyclotron-emission-diagnostic-in-tcv
#8
M Fontana, L Porte, P Molina Cabrera
The correlation electron cyclotron emission diagnostic of tokamak à configuration variable has recently been upgraded. It now has the choice of three lines of sight: two horizontal lines placed on the low field side of the vessel, perpendicular to the magnetic field, and a dual-axis steerable antenna. The polarization of the radiation collected by the latter can be rotated using a universal polarizer situated in the transmission line. This line is also shared with a reflectometry system, allowing simultaneous measurements of temperature and density fluctuations in the same plasma volumes...
August 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28863342/molecular-transformation-of-natural-and-anthropogenic-dissolved-organic-matter-under-photo-irradiation-in-the-presence-of-nano-tio2
#9
Jitao Lv, Dan Li, Lei Luo, Tong Wu, Shuzhen Zhang
Photochemical transformation of dissolved organic matter (DOM) plays a very important role in the cycling of organic carbon in aquatic systems. Increasing release of photoactive nanoparticles such as titanium dioxide nanoparticles (nano TiO2) into surface water may impact this process. The present study employed Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) to examine the molecular transformation of natural DOM (peat DOM, DOMp) and anthropogenic DOM (sludge-derived DOM, DOMs) under photo-irradiation as affected by nano TiO2...
August 26, 2017: Water Research
https://www.readbyqxmd.com/read/28862209/accelerator-driven-neutron-source-design-via-beryllium-target-and-208-pb-moderator-for-boron-neutron-capture-therapy-in-alternative-treatment-strategy-by-monte-carlo-method
#10
Abdollah Khorshidi
AIMS: The reactor has increased its area of application into medicine especially boron neutron capture therapy (BNCT); however, accelerator-driven neutron sources can be used for therapy purposes. The present study aimed to discuss an alternative method in BNCT functions by a small cyclotron with low current protons based on Karaj cyclotron in Iran. MATERIALS AND METHODS: An epithermal neutron spectrum generator was simulated with 30 MeV proton energy for BNCT purposes...
July 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28844298/uv-vis-degradation-of-%C3%AE-tocopherol-in-a-model-system-and-in-a-cosmetic-emulsion-structural-elucidation-of-photoproducts-and-toxicological-consequences
#11
Ségolène De Vaugelade, Edith Nicol, Svetlana Vujovic, Sophie Bourcier, Stéphane Pirnay, Stéphane Bouchonnet
The UV-vis photodegradation of α-tocopherol was investigated in a model system and in a cosmetic emulsion. Both gas chromatography coupled with tandem mass spectrometry (GC-MS/MS) and high performance liquid chromatography coupled with ultrahigh resolution Fourier transform ion cyclotron resonance mass spectrometry (LC-UHR-MS) were used for photoproducts structural identification. Nine photoproduct families were detected and identified based on their mass spectra and additional experiments with α-tocopherol-d9; phototransformation mechanisms were postulated to rationalize their formation under irradiation...
August 8, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28840311/molecular-interaction-study-of-flavonoids-with-human-serum-albumin-using-native-mass-spectrometry-and-molecular-modeling
#12
Bohong Wang, Qian Qin, Mengmeng Chang, Shuyan Li, Xianzhe Shi, Guowang Xu
Noncovalent interactions between proteins and small-molecule ligands widely exist in biological bodies and play significant roles in many physiological and pathological processes. Native mass spectrometry (MS) has emerged as a new powerful tool to study noncovalent interactions by directly analyzing the ligand-protein complexes. In this work, an ultrahigh-resolution native MS method based on a 15-T SolariX XR Fourier transform ion cyclotron resonance mass spectrometer was firstly used to investigate the interaction between human serum albumin (HSA) and flavonoids...
August 24, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28838027/n-butyl-4-hydroxy-1-8-naphthalimide-a-new-matrix-for-small-molecule-analysis-by-matrix-assisted-laser-desorption-ionization-mass-spectrometry
#13
Xina Cheng, Xueting Ye, Dan Liu, Nan Zhao, Huiyuan Gao, Ping Wang, Guangbo Ge, Xiaozhe Zhang
RATIONALE: The matrix plays an essential role in defining detection limits and ionization yields of analytes in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) analysis. Small molecule MALDI-MS analyses commonly suffer from the high background interference generated from matrices. Moreover, the inhomogeneous crystallization of some matrices, such as 2,5-dihydroxybenzoic acid (DHB), is to the detriment of the quality or repeatability of detection. We have found that N-butyl-4-hydroxy-1,8-naphthalimide (BHN) can provide improved performance as a matrix for small molecule analysis...
August 24, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28835959/-alcl3-bnme2-tacn-a-new-metal-chelate-scaffold-for-radiofluorination-by-cl-f-exchange
#14
William Levason, Sajinder K Luthra, Graeme McRobbie, Francesco M Monzittu, Gillian Reid
Radiofluorination of a 2.63 μM solution (pH 4, NaOAc buffer) of [AlCl3(BnMe2-tacn)] via treatment with 2.99 mol. equiv. of [(19)F]KF doped with cyclotron-produced [(18)F]F(-) target water, with heating to 80-100 °C for 1 h, gives up to 24% (18)F incorporation. SPE purification of the [Al(19)F2(18)F(BnMe2-tacn)] radio-product gives >99% RCP, with excellent stability (>99% RCP after 3 h).
August 24, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28830022/measurement-of-43-sc-and-44-sc-production-cross-section-with-an-18mev-medical-pet-cyclotron
#15
Tommaso Stefano Carzaniga, Martin Auger, Saverio Braccini, Maruta Bunka, Antonio Ereditato, Konrad Pawel Nesteruk, Paola Scampoli, Andreas Türler, Nicholas van der Meulen
(43)Sc and (44)Sc are positron emitter radionuclides that, in conjunction with the β(-) emitter (47)Sc, represent one of the most promising possibilities for theranostics in nuclear medicine. Their availability in suitable quantity and quality for medical applications is an open issue and their production with medical cyclotrons represents a scientific and technological challenge. For this purpose, an accurate knowledge of the production cross sections is mandatory. In this paper, we report on the cross section measurement of the reactions (43)Ca(p,n)(43)Sc, (44)Ca(p,2n) (43)Sc, (46)Ti(p,α)(43)Sc, and (44)Ca(p,n)(44)Sc at the Bern University Hospital cyclotron...
August 10, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28830000/fate-and-abundance-of-classical-and-heteroatomic-naphthenic-acid-species-after-advanced-oxidation-processes-insights-and-indicators-of-transformation-and-degradation
#16
Mohamed N A Meshref, Pamela Chelme-Ayala, Mohamed Gamal El-Din
The toxicological effects from all components in oil sands process-affected water (OSPW) are not known. Alternatively, monitoring the variations and abundance of different classes and compounds after treatments might be a useful approach in OSPW remediation. In this study, the variations in the compositions of classical and heteroatomic naphthenic acids (NAs) after treatment using advanced oxidation processes (AOPs), mainly ozone and peroxone, and two different mass spectrometry methods; ultra-performance liquid chromatography time-of-flight (UPLC-TOFMS) and Fourier transform ion cyclotron resonance (FTICR-MS), were examined...
August 4, 2017: Water Research
https://www.readbyqxmd.com/read/28826521/exploring-metabolism-in-vivo-using-endogenous-11-c-metabolic-tracers
#17
REVIEW
Kiel Neumann, Robert Flavell, David M Wilson
Cancer and other diseases are increasingly understood in terms of their metabolic disturbances. This thinking has revolutionized the field of ex vivo metabolomics and motivated new approaches to detect metabolites in living systems, including proton magnetic resonance spectroscopy ((1)H-MRS), hyperpolarized (13)C MRS, and PET. For PET, imaging abnormal metabolism in vivo is hardly new. Positron-labeled small-molecule metabolites have been used for decades in humans, including (18)F-FDG, which is used frequently to detect upregulated glycolysis in tumors...
September 2017: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/28819889/visualization-of-57-fe-labeled-heme-isotopic-fine-structure-and-localization-of-regions-of-erythroblast-maturation-in-mouse-spleen-by-maldi-fticr-ms-imaging
#18
Makoto Kihara, Yukari Matsuo-Tezuka, Mariko Noguchi-Sasaki, Keigo Yorozu, Mitsue Kurasawa, Yasushi Shimonaka, Michinori Hirata
Epoetin beta pegol (continuous erythropoiesis receptor activator; C.E.R.A.), or methoxy-polyethylene glycol-modified epoetin beta, is a long-acting erythropoiesis stimulating agent (ESA) that effectively maintains hemoglobin levels. It promotes proliferation of erythroid progenitor cells in hematopoietic organs and leads to increased reticulocyte and hemoglobin levels. However, the detailed erythropoietic effects of various ESAs on their target organs have yet to be clarified, and new approaches are needed to analyze tissue iron localization with structural information...
August 17, 2017: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/28804186/-47-sc-production-development-by-cyclotron-irradiation-of-48-ca
#19
R Misiak, R Walczak, B Wąs, M Bartyzel, J W Mietelski, A Bilewicz
The therapeutic radionuclide (47)Sc was produced through the (48)Ca(p,2n) channel on a proton beam accelerator. The obtained results show that the optimum proton energies are in the range of 24-17 MeV, giving the possibility to produce (47)Sc radionuclide containing 7.4% of (48)Sc. After activation, the powdery CaCO3 target material was dissolved in HCl and scandium isotopes were isolated from the targets. The performed separation experiments indicate that, due to the simplicity of the operations and the chemical purity of the obtained (47)Sc the best separation process is when scandium radioisotopes are separated on the 0...
2017: Journal of Radioanalytical and Nuclear Chemistry
https://www.readbyqxmd.com/read/28800703/mechanism-of-reduction-in-igg-and-ige-binding-of-%C3%AE-lactoglobulin-induced-by-ultrasound-pretreatment-combined-with-dry-state-glycation-a-study-using-conventional-spectrometry-and-high-resolution-mass-spectrometry
#20
Wenhua Yang, Zongcai Tu, Hui Wang, Lu Zhang, Shengsheng Xu, Chendi Niu, Honglin Yao, Igor A Kaltashov
Bovine β-lactoglobulin (β-Lg) is one of major allergens in cow's milk. Previous study showed that ultrasound treatment induced the conformational changes of β-Lg and promoted the glycation in aqueous solutions, which is, however, less efficient compared with dry-state. In this work, the effect of ultrasound pretreatment combined with dry-state glycation on the IgG and IgE binding of β-Lg was studied. Dry-state glycation with mannose after ultrasound pretreatment at 0-600 W significantly reduced the IgG and IgE binding of β-Lg, with the lowest values observed at 400 W...
August 29, 2017: Journal of Agricultural and Food Chemistry
keyword
keyword
115150
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"