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https://www.readbyqxmd.com/read/29144407/the-effects-of-various-weather-conditions-as-a-potential-ischemic-stroke-trigger-in-dogs
#1
Kristy L Meadows, Gena M Silver
Stroke is the fifth leading cause of death in the United States, and is the leading cause of serious, long-term disability worldwide. There are at least 795,000 new or recurrent strokes each year, and approximately 85% of all stroke occurrences are ischemic. Unfortunately, companion animals are also at risk for ischemic stroke. Although the exact incidence of ischemic stroke in companion animals is unknown, some studies, and the veterinary information network (VIN), report that approximately 3% of neurological case referrals are due to a stroke...
November 16, 2017: Veterinary Sciences
https://www.readbyqxmd.com/read/29143688/investigating-management-choices-for-canine-heartworm-disease-in-northern-mississippi
#2
Tobi N Ku
BACKGROUND: There are concerns that the chronic use of macrocyclic lactone preventives to kill adult heartworms ("soft-" or "slow-kill") may have contributed to the development of macrocyclic lactone resistance. This prospective analysis was designed to expand our understanding of currently employed treatment decisions, protocols utilized in a "slow-kill" methodology, and trends in heartworm prevention in a region with concerns about macrocyclic lactone resistance. We tested the hypothesis that practitioners underestimate the actual percentage of heartworm-positive dogs treated with "slow-kill" therapy...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29143687/prevalence-and-epidemiology-of-canine-and-feline-heartworm-infection-in-taiwan
#3
Ta-Li Lu, Jun-Yue Wong, Ta-Lun Tan, Yong-Wei Hung
BACKGROUND: Heartworm, Dirofilaria immitis, has long been recognized in Taiwanese dogs but feline heartworm infection has been largely overlooked by veterinarians and pet owners. The main goal of this study was to determine the prevalence and epidemiology of canine and feline heartworm infection in Taiwan. METHODS: Household dogs and cats were selected from 103 veterinary hospitals in 13 cities throughout Taiwan. All animals were at least 1 year old, had received no heartworm prevention for more than 1 year, and had lived in the same city for at least 1 year...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29143666/comparative-evaluation-of-commercially-available-point-of-care-heartworm-antigen-tests-using-well-characterized-canine-plasma-samples
#4
Lindsay A Starkey, Joy V Bowles, Mark E Payton, Byron L Blagburn
BACKGROUND: Dirofilaria immitis is a worldwide parasite that is endemic in many parts of the United States. There are many commercial assays available for the detection of D. immitis antigen, one of which was modified and has reentered the market. Our objective was to compare the recently reintroduced Witness® Heartworm (HW) Antigen test Kit (Zoetis, Florham Park, NJ) and the SNAP® Heartworm RT (IDEXX Laboratories, Inc., Westbrook, ME) to the well-based ELISA DiroChek® Heartworm Antigen Test Kit (Zoetis, Florham Park, NJ)...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29143657/clinical-benefits-of-incorporating-doxycycline-into-a-canine-heartworm-treatment-protocol
#5
C Thomas Nelson, Elizabeth S Myrick, Thomas A Nelson
BACKGROUND: The objective of heartworm treatment is to improve the clinical condition of the patient and to eliminate pre-cardiac, juvenile, and adult worm stages with minimal complications. Pulmonary thromboembolisms are an inevitable consequence of worm death and can result in severe pulmonary reactions and even death of the patient. To minimize these reactions, various treatment protocols involving melarsomine, the only adulticidal drug approved by the US Food and Drug Administrations (FDA), in conjunction with macrocyclic lactone heartworm preventives and glucocorticosteroids have been advocated...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29143650/microfilarial-reduction-following-proheart%C3%A2-6-and-proheart%C3%A2-sr-12-treatment-in-dogs-experimentally-inoculated-with-a-resistant-isolate-of-dirofilaria-immitis
#6
Tom L McTier, Aleah Pullins, Gregory A Inskeep, Genevieve Gagnon, Huihao Fan, Adam Schoell, Tara Bidgood, Joyce Login, Patrick Meeus
BACKGROUND: Emerging resistance of heartworms (Dirofilaria immitis) to macrocyclic lactone (ML) preventives is an increasing concern for veterinarians, pet owners and animal health companies that supply heartworm preventives, with recent reports of resistant isolates identified from the Mississippi Delta region of the United States. Products that are effective in eliminating microfilariae (MF) in dogs harboring resistant heartworm infections could be important in reducing the spread of heartworm resistance...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29143645/impact-of-heat-treatment-on-dirofilaria-immitis-antigen-detection-in-shelter-dogs
#7
Brian A DiGangi, Carly Dworkin, Jason W Stull, Jeanette O'Quin, Morgan Elser, Antoinette E Marsh, Lesli Groshong, Wendy Wolfson, Brandy Duhon, Katie Broaddus, Elise N Gingrich, Emily Swiniarski, Elizabeth A Berliner
BACKGROUND: The diagnosis and management of canine heartworm disease is a growing concern for shelter veterinarians. Although the accuracy of commercial antigen test kits has been widely studied, recent reports have renewed interest in antigen blocking as a causative factor for false "no antigen detected" results. The objectives of this study were to determine the prevalence of false "no antigen detected" results in adult dogs entering shelters in northern, southern, and western regions of the country and to identify historical and clinical risk factors for such results...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29143643/subcutaneous-dirofilariosis-dirofilaria-repens-an-infection-spreading-throughout-the-old-world
#8
REVIEW
Claudio Genchi, Laura Kramer
BACKGROUND: Two main Dirofilaria species infect dogs: D. immitis and D. repens. While D. immitis has a worldwide distribution, D. repens is currently found only in Europe, Asia, and Africa. Adult D. repens are located in subcutaneous tissues of natural hosts where they survive for long periods of time. First-stage larvae, microfilariae, circulate in the peripheral bloodstream, where they are taken up by the mosquito intermediate hosts. Infected mosquitoes then transmit infective third-stage (L3) larvae to new hosts through the blood meal...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29141638/diffusion-weighted-imaging-of-the-brains-of-dogs-with-idiopathic-epilepsy
#9
Antje Hartmann, Steffen Sager, Klaus Failing, Marion Sparenberg, Martin J Schmidt
BACKGROUND: Idiopathic epilepsy is one of the most common neurological disorders in dogs. Unfortunately, up to 30% of dogs with idiopathic epilepsy show no improvement under antiepileptic drug treatment. Diffusion-weighted imaging is used in human medicine to identify epileptogenic foci in the brain to allow for more invasive treatments such as deep brain stimulation or surgical removal. The aim of this study was to ass the feasibility of interictal diffusion-weighted MRI in dogs and to evaluate the distribution of diffusion in the brains of dogs with idiopathic epilepsy (IE) and to compare these values to previously published values from healthy beagle dogs...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29141627/in-vitro-properties-of-concentrated-canine-platelets-stored-in-two-additive-solutions-a-comparative-study
#10
N Hlavac, C S Lasta, M L Dalmolin, L A Lacerda, D de Korte, N A Marcondes, S R Terra, F B Fernandes, F H D González
BACKGROUND: Platelet transfusion therapy poses many challenges in veterinary clinical practice. Lack of readily available blood donors, short shelf-life, and inability to administer a sufficient number of platelets to meet a dog's transfusion need are the major difficulties encountered. Platelet additive solutions are already in use at American and European human blood banks, showing to be a realistic alternative. This study compares the in vitro platelet function in plasma, Composol, or SSP+ during storage for 13 days...
November 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29140262/influence-of-professional-affiliation-on-expert-s-view-on-welfare-measures
#11
Nina Dam Otten, Tine Rousing, Björn Forkman
The present study seeks to investigate the influence of expert affiliation in the weighing procedures within animal welfare assessments. Experts are often gathered with different backgrounds with differing approaches to animal welfare posing a potential pitfall if affiliation groups are not balanced in numbers of experts. At two time points (2012 and 2016), dairy cattle and swine experts from four different stakeholder groups, namely researchers (RES), production advisors (CONS), practicing veterinarians (VET) and animal welfare control officers (AWC) were asked to weigh eight different welfare criteria: Hunger, Thirst, Resting comfort, Ease of movement, Injuries, Disease, Human-animal bond and Emotional state...
November 15, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/29140260/vaccinia-virus-natural-infections-in-brazil-the-good-the-bad-and-the-ugly
#12
REVIEW
Jaqueline Silva de Oliveira, Poliana de Oliveira Figueiredo, Galileu Barbosa Costa, Felipe Lopes de Assis, Betânia Paiva Drumond, Flávio Guimarães da Fonseca, Maurício Lacerda Nogueira, Erna Geessien Kroon, Giliane de Souza Trindade
The orthopoxviruses (OPV) comprise several emerging viruses with great importance to human and veterinary medicine, including vaccinia virus (VACV), which causes outbreaks of bovine vaccinia (BV) in South America. Historically, VACV is the most comprehensively studied virus, however, its origin and natural hosts remain unknown. VACV was the primary component of the smallpox vaccine, largely used during the smallpox eradication campaign. After smallpox was declared eradicated, the vaccination that conferred immunity to OPV was discontinued, favoring a new contingent of susceptible individuals to OPV...
November 15, 2017: Viruses
https://www.readbyqxmd.com/read/29139145/pharmacokinetic-assessment-of-the-monepantel-plus-oxfendazole-combined-administration-in-dairy-cows
#13
M Ballent, P Viviani, F Imperiale, P Dominguez, S Halwachs, H Mahnke, W Honscha, C Lanusse, G Virkel, A Lifschitz
Monepantel (MNP) is a novel anthelmintic compound launched into the veterinary pharmaceutical market. MNP is not licenced for use in dairy animals due to the prolonged elimination of its metabolite monepantel sulphone (MNPSO2 ) into milk. The goal of this study was to evaluate the presence of potential in vivo drug-drug interactions affecting the pattern of milk excretion after the coadministration of the anthelmintics MNP and oxfendazole (OFZ) to lactating dairy cows. The concentrations of both parent drugs and their metabolites were measured in plasma and milk samples by HPLC...
November 15, 2017: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29138745/spontaneous-nervous-system-concussion-in-dogs-a-description-of-two-cases-and-a-review-of-terminology-in-veterinary-medicine
#14
Angelo Pasquale Giannuzzi, Antonio De Simone, Mario Ricciardi
In human medicine, central nervous system (CNS) concussion is defined as a transient neurological dysfunction following a traumatic event, without evidence of structural abnormalities of the affected region on advanced diagnostic imaging. Depending on the anatomical region involved, three forms of concussive syndromes are described: brain concussion, spinal concussion and cerebellar concussion. Although major textbooks of veterinary neurology admit the existence of canine brain concussion, spontaneous cases of this pathological condition have not been reported in small animals so far...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/29138693/investigations-on-the-occurrence-and-associated-risk-factors-of-avian-coccidiosis-in-osun-state-southwestern-nigeria
#15
Shola David Ola-Fadunsin
Avian coccidiosis is one of the most important diseases of poultry and it is responsible for a large number of poultry mortalities worldwide. This study was carried out to investigate the occurrence and associated risk factors of avian coccidiosis in Osun State, Nigeria. Fecal samples were collected and examined from 5,544 avian species that were brought for treatment at the state veterinary hospitals over a 10-year period. Parameters such as age, sex, season, and species of birds were determined. Also, the months of the year were taken into consideration...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/29137887/effects-of-chlortetracycline-on-the-fate-of-multi-antibiotic-resistance-genes-and-the-microbial-community-during-swine-manure-composting
#16
Zhiqiang Chen, Yao Wang, Qinxue Wen
Excessive use of antibiotics in breeding industry leads to accumulation of antibiotic residuals and antibiotic resistance genes (ARGs) in environment from improperly treated livestock excrements. Four commonly used veterinary antibiotics including chlortetracycline (CTC), sulfamerazine (SMZ), enrofloxacin (ENR) and erythromycin (ERY) were monitored in the swine manure composting. Co-resistance and cross-resistance effects among relative ARGs, correlations between ARGs and bacterial community under multiple antibiotics residual during the composting were investigated in this research...
November 11, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29137329/development-of-a-radiolabeled-caninized-anti-egfr-antibody-for-comparative-oncology-trials
#17
Judit Fazekas-Singer, Neydher Berroterán-Infante, Christina Rami-Mark, Monika Dumanic, Miroslawa Matz, Michael Willmann, Fritz Andreae, Josef Singer, Wolfgang Wadsak, Markus Mitterhauser, Erika Jensen-Jarolim
Due to large homology of human and canine EGFR, dogs suffering from spontaneous EGFR+ cancer can be considered as ideal translational models. Thereby, novel immunotherapeutic compounds can be developed for both human and veterinary patients. This study describes the radiolabeling of a canine anti-EGFR IgG antibody (can225IgG) with potential diagnostic and therapeutic value in comparative clinical settings. Can225IgG was functionalized with DTPA for subsequent chelation with the radionuclide (99m)Tc. Successful coupling of 10 DTPA molecules per antibody on average was proven by significant mass increase in MALDI-TOF spectroscopy, gel electrophoresis and immunoblots...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29136156/increase-in-antimicrobial-resistance-and-emergence-of-major-international-high-risk-clonal-lineages-in-dogs-and-cats-with-urinary-tract-infection-16-year-retrospective-study
#18
Cátia Marques, Adriana Belas, Andreia Franco, Catarina Aboim, Luís Telo Gama, Constança Pomba
Objectives: To evaluate temporal trends in antimicrobial resistance, over 16 years, in bacteria isolated from dogs and cats with urinary tract infection (UTI) and the clonal lineages of bacteria harbouring critical antimicrobial resistance mechanisms. Methods: Antimicrobial susceptibility testing was conducted for 948 bacteria isolated from dogs and cats with UTI (1999-2014). Resistance mechanisms were detected by PCR, namely ESBL/AmpC in third-generation cephalosporin (3GC)-resistant Escherichia coli and Proteus mirabilis, mecA in methicillin-resistant staphylococci, and aac(6')-Ieaph(2″)-Ia and aph(2″)-1d in high-level gentamicin-resistant (HLGR) enterococci...
November 9, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29134728/recent-advances-in-veterinary-radiation-oncology
#19
EDITORIAL
Michael S Kent, Michelle M Turek, John Farrelly
No abstract text is available yet for this article.
November 13, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/29133148/adventitious-viruses-in-insect-cell-lines-used-for-recombinant-protein-expression
#20
REVIEW
Christoph Geisler, Donald L Jarvis
Insect cells are widely used for recombinant protein expression, typically as hosts for recombinant baculovirus vectors, but also for plasmid-mediated transient transfection or stable genetic transformation. Insect cells are used to express proteins for research, as well as to manufacture biologicals for human and veterinary medicine. Recently, several insect cell lines used for recombinant protein expression were found to be persistently infected with adventitious viruses. This has raised questions about how these infections might affect research performed using those cell lines...
November 10, 2017: Protein Expression and Purification
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