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https://www.readbyqxmd.com/read/28325030/application-of-meg-coherence-in-lateralization-of-mtle
#1
Mohammad R Nazem-Zadeh, Susan M Bowyer, John E Moran, Esmaeil Davoodi-Bojd, Andrew Zillgitt, Hassan Bagher-Ebadian, Fariborz Mahmoudi, Kost V Elisevich, Hamid Soltanian-Zadeh
Magnetoencephalography (MEG) is a noninvasive imaging method for localization of focal epileptiform activity in patients with epilepsy. This study investigates the cerebral functional abnormalities quantified by MEG coherence laterality in mesial temporal lobe epilepsy (mTLE). Resting state MEG data was analyzed using MEG coherence source imaging (MEG-CSI) method to determine the coherence in 54 anatomical sites in 12 adult mTLE patients and 12 age- and gender-matched controls. MEG coherence laterality, after Bonferroni adjustment, showed significant differences for right versus left mTLE in insular cortex and both lateral orbitofrontal and superior temporal gyri (p<;0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28325029/noninvasive-eeg-correlates-of-overground-and-stair-walking
#2
Justin A Brantley, Trieu Phat Luu, Recep Ozdemir, Fangshi Zhu, Anna T Winslow, Helen Huang, Jose L Contreras-Vidal
Automated walking intention detection remains a challenge in lower-limb neuroprosthetic systems. Here, we assess the feasibility of extracting motor intent from scalp electroencephalography (EEG). First, we evaluated the corticomuscular coherence between central EEG electrodes (C1, Cz, C2) and muscles of the shank and thigh during walking on level ground and stairs. Second, we trained decoders to predict the linear envelope of the surface electromyogram (EMG). We observed significant EEG-led corticomuscular coupling between electrodes and sEMG (tibialis anterior) in the high delta (3-4 Hz) and low theta (4-5 Hz) frequency bands during level walking, indicating efferent signaling from the cortex to peripheral motor neurons...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324944/biclustering-strategies-for-genetic-marker-selection-in-gynecologic-tumor-cell-lines
#3
A Alevyzaki, S Sfakianakis, E S Bei, E Obermayr, R Zeillinger, D Fotiadis, M Zervakis
Over the past few decades great interest has been focused on cell lines derived from tumors, because of their usability as models to understand the biology of cancer. At the same time, advanced technologies such as DNA-microarrays have been broadly used to study the expression level of thousands of genes in primary tumors or cancer cell lines in a single experiment. Results from microarray analysis approaches have provided valuable insights into the underlying biology and proven useful for tumor classification, prognostication and prediction...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324943/overcoming-spatio-temporal-limitations-using-dynamically-scaled-in-vitro-pc-mri-a-flow-field-comparison-to-true-scale-computer-simulations-of-idealized-stented-and-patient-specific-left-main-bifurcations
#4
Susann Beier, John Ormiston, Mark Webster, John Cater, Stuart Norris, Pau Medrano-Gracia, Alistair Young, Kathleen Gilbert, Brett Cowan
The majority of patients with angina or heart failure have coronary artery disease. Left main bifurcations are particularly susceptible to pathological narrowing. Flow is a major factor of atheroma development, but limitations in imaging technology such as spatio-temporal resolution, signal-to-noise ratio (SNRv), and imaging artefacts prevent in vivo investigations. Computational fluid dynamics (CFD) modelling is a common numerical approach to study flow, but it requires a cautious and rigorous application for meaningful results...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324930/rtms-enhanced-gamma-oscillation-through-strengthened-network-connection
#5
Mengmeng Dou, Xin Tian
Gamma oscillations emerge generally in working memory to aspect of higher cognitive functions, and typically with the interaction of brain network. How is gamma oscillatory activity influenced by the functional connection in the brain'a network? How can gamma oscillations be increased by neural modulation to result in potential benefits for working memory? The present study aims to investigate the intensity of gamma oscillations modulated by low frequency repetitive transcranial magnetic stimulation (rTMS), and the possible brain network mechanism of increased gamma oscillations during working memory task in rats...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324792/tolerance-of-uncertainty-conceptual-analysis-integrative-model-and-implications-for-healthcare
#6
REVIEW
Marij A Hillen, Caitlin M Gutheil, Tania D Strout, Ellen M A Smets, Paul K J Han
RATIONALE: Uncertainty tolerance (UT) is an important, well-studied phenomenon in health care and many other important domains of life, yet its conceptualization and measurement by researchers in various disciplines have varied substantially and its essential nature remains unclear. OBJECTIVE: The objectives of this study were to: 1) analyze the meaning and logical coherence of UT as conceptualized by developers of UT measures, and 2) develop an integrative conceptual model to guide future empirical research regarding the nature, causes, and effects of UT...
March 14, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28324609/optical-coherence-microscopy
#7
Rainer A Leitgeb
The present chapter aims at demonstrating the capabilities of optical coherence microscopy (OCM) for applications in biomedical imaging. We furthermore review the functional imaging capabilities of OCM focusing on lable-free optical angiography. We conclude with a section on digital wavefront control and a short outlook on future developments, in particular for contrast enhancement techniques.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28324116/thick-prelaminar-tissue-decreases-lamina-cribrosa-visibility
#8
Katie A Lucy, Bo Wang, Joel S Schuman, Richard A Bilonick, Yun Ling, Larry Kagemann, Ian A Sigal, Ireneusz Grulkowski, Jonathan J Liu, James G Fujimoto, Hiroshi Ishikawa, Gadi Wollstein
Purpose: Evaluation of the effect of prelaminar tissue thickness on visualization of the lamina cribrosa (LC) using optical coherence tomography (OCT). Methods: The optic nerve head (ONH) region was scanned using OCT. The quality of visible LC microstructure was assessed subjectively using a grading system and objectively by analyzing the signal intensity of each scan's superpixel components. Manual delineations were made separately and in 3-dimensions quantifying prelaminar tissue thickness, analyzable regions of LC microstructure, and regions with a visible anterior LC (ALC) boundary...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28324111/arap1-deficiency-causes-photoreceptor-degeneration-in-mice
#9
Ala Moshiri, Devin Humpal, Brian C Leonard, Denise M Imai, Addy Tham, Lynette Bower, Dave Clary, Thomas M Glaser, K C Kent Lloyd, Christopher J Murphy
Purpose: Small guanosine triphosphatase (GTPase) ADP-ribosylation factors (Arfs) regulate membrane traffic and actin reorganization under the control of GTPase-activating proteins (GAPs). Arap1 is an Arf-directed GAP that inhibits the trafficking of epidermal growth factor receptor (EGFR) to the early endosome, but the diversity of its functions is incompletely understood. The aim of this study was to determine the role of Arap1 in the mammalian retina. Methods: Genetically engineered Arap1 knockout mice were screened for ocular abnormalities in the National Institutes of Health Knockout Mouse Production and Phenotyping (KOMP2) Project...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28323591/treatment-and-monitoring-of-central-serous-chorioretinopathy-in-pilots
#10
Ari Shinojima, Ryusaburo Mori, Kyoko Fujita, Mitsuko Yuzawa
BACKGROUND: Central serous chorioretinopathy (CSC), which has the characteristics of a serous retinal detachment (SRD) in the macular area, affects mostly men in the 30- to 50-yr age range. Some patients have persistent SRD, which may cause retinal thinning and photoreceptor impairment. CSC symptoms are gradual vision loss and/or metamorphopsia. Some commercial airline pilots are concerned about CSC symptoms, which can disqualify them from flying for months and can also reoccur. Thus, careful monitoring and treatment of CSC are critical for pilots, especially those with chronic or recurrent CSC...
December 1, 2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28323496/dengue-fever-presenting-as-purtscher-like-retinopathy
#11
Luiz H Lima, Silvana Vianello, Sérgio Pimentel, Gabriel Costa de Andrade, Claudio Zett, Léo Muller, Michel E Farah, Rubens Belfort
PURPOSE: To report the fundus manifestations and spectral-domain optical coherence tomographic (SD-OCT) features of dengue fever presenting as Purtscher-like retinopathy. METHODS: Retrospective review of two cases of dengue fever. RESULTS: Color fundus photograph revealed the presence of cotton-wool spots in a Purtscher-like configuration in the posterior pole of all study eyes. SD-OCT demonstrated increased reflectivity signal in the inner retinal layers, and after a variable follow-up period, there was complete disappearance of cotton-wool spots and persistence of the hyperreflectivity signal...
March 21, 2017: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/28319789/group-schema-therapy-for-personality-disorders-a-pilot-study-for-implementation-in-acute-psychiatric-in-patient-settings
#12
Igor Nenadić, Sina Lamberth, Neele Reiss
Group schema therapy (GST) has been proposed as a novel long-term treatment programme for borderline and cluster C personality disorders. We implemented a short-term GST programme (12-15 sessions, based on the manual by Farrell and Shaw (2012), including both cognitive / behavioural and experiential interventions for in-patients (n=9) with either borderline or cluster C personality disorders (and axis I co-morbidities) treated in a (sub)acute psychiatric in-patient setting. We evaluated pre- and post-treatment self-report of maladaptive and adaptive schema modes (using the SMI) and early maladaptive schemas (YSQ-3), as well as overall symptom severity (brief symptom check list, BSCL-53-S), patient satisfaction (ZUF-8) and group climate and coherence (GCQ-S)...
February 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28319641/correlation-of-visually-evoked-functional-and-blood-flow-changes-in-the-rat-retina-measured-with-a-combined-oct-erg-system
#13
Bingyao Tan, Erik Mason, Benjamin MacLellan, Kostadinka K Bizheva
Purpose: To correlate visually evoked functional and blood flow changes in the rat retina measured simultaneously with a combined optical coherence tomography and electroretinography system (OCT+ERG). Methods: Male Brown Norway (n = 6) rats were dark adapted and anesthetized with ketamine/xylazine. Visually evoked changes in the retinal blood flow (RBF) and functional response were measured simultaneously with an OCT+ERG system with 3-μm axial resolution in retinal tissue and 47-kHz image acquisition rate...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28319450/retinal-and-choroidal-thickness-in-adult-patients-with-familial-mediterranean-fever
#14
Tolga Bicer, Osman Celikay, Mustafa Kosker, Muhammed Yunus Alp, Cem Ozisler, Ahmet Yesilyurt, Burcu Kucuk Bicer, Canan Gurdal
PURPOSE: We aimed to evaluate changes in retinal, choroidal, ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL) thicknesses in genetically diagnosed adult patients with familial Mediterranean fever (FMF). METHODS: A total of 50 eyes of 50 genetically diagnosed patients with FMF and 50 eyes of controls were analyzed. Patients were recruited from the Genetic Diagnostic Center of Dışkapı Yıldırım Beyazıt Research and Training Hospital, Turkey. Retinal and choroidal thicknesses were obtained using spectral-domain optical coherence tomography from choroid, retina, GCC, and RNFL...
March 20, 2017: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/28319388/visualizing-intramolecular-vibrational-redistribution-in-cyclotrimethylene-trinitramine-rdx-crystal-by-multiplex-coherent-anti-stokes-raman-scattering
#15
Guoyang Yu, Yangyang Zeng, Wencan Guo, Honglin Wu, Gangbei Zhu, Zhaoyang Zheng, Xianxu Zheng, Yunfei Song, Yanqiang Yang
The femtosecond time-resolved multiplex coherent anti-Stokes Raman scattering (CARS) technique has been performed to investigate the intramolecular vibrational redistribution (IVR) through vibrational couplings in RDX molecules. In the multiplex CARS experiment, the supercontinuum (SC) was used as broadband Stokes light to coherently and collectively excite multiple vibrational modes, and quantum beats arising from vibrational couplings among these modes were observed. The IVR of RDX is visualized by a topological graph of these vibrational couplings...
March 20, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28319274/intraoperative-optical-coherence-tomography-for-soft-tissue-sarcoma-differentiation-and-margin-identification
#16
Kelly J Mesa, Laura E Selmic, Paritosh Pande, Guillermo L Monroy, Jennifer Reagan, Jonathan Samuelson, Elizabeth Driskell, Joanne Li, Marina Marjanovic, Eric J Chaney, Stephen A Boppart
BACKGROUND AND OBJECTIVE: Sarcomas are rare but highly aggressive tumors, and local recurrence after surgical excision can occur in up to 50% cases. Therefore, there is a strong clinical need for accurate tissue differentiation and margin assessment to reduce incomplete resection and local recurrence. The purpose of this study was to investigate the use of optical coherence tomography (OCT) and a novel image texture-based processing algorithm to differentiate sarcoma from muscle and adipose tissue...
March 20, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28319160/psychometric-assessment-of-the-chinese-version-of-the-brief-illness-perception-questionnaire-in-breast-cancer-survivors
#17
Na Zhang, Richard Fielding, Inda Soong, Karen K K Chan, Conrad Lee, Alice Ng, Wing Kin Sze, Janice Tsang, Victor Lee, Wendy Wing Tak Lam
OBJECTIVE: The eight-item Brief Illness Perception Questionnaire (B-IPQ) supposedly evaluates cognitive and emotional representations of illness. This study examined the validity and reliability of a traditional Chinese version of the B-IPQ in Hong Kong Chinese breast cancer survivors. METHODS: 358 Chinese breast cancer survivors who had recently ended their primary treatment completed this B-IPQ Chinese version. Confirmatory factor analysis (CFA) tested the factor structure...
2017: PloS One
https://www.readbyqxmd.com/read/28318888/characterization-of-the-lung-parenchyma-using-ultrasound-multiple-scattering
#18
Kaustav Mohanty, John Blackwell, Thomas Egan, Marie Muller
The purpose of the study described here was to showcase the application of ultrasound to quantitative characterization of the micro-architecture of the lung parenchyma to predict the extent of pulmonary edema. The lung parenchyma is a highly complex and diffusive medium for which ultrasound techniques have remained qualitative. The approach presented here is based on ultrasound multiple scattering and exploits the complexity of ultrasound propagation in the lung structure. The experimental setup consisted of a linear transducer array with an 8-MHz central frequency placed in contact with the lung surface...
March 16, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28318638/optical-coherence-tomography-guided-decisions-in-retinoblastoma-management
#19
Sameh E Soliman, Cynthia VandenHoven, Leslie D MacKeen, Elise Héon, Brenda L Gallie
PURPOSE: Assess the role of handheld optical coherence tomography (OCT) in guiding management decisions during diagnosis, treatment, and follow-up of eyes affected by retinoblastoma. DESIGN: Retrospective, noncomparative, single-institution case series. PARTICIPANTS: All children newly diagnosed with retinoblastoma from January 2011 to December 2015 who had an OCT session during their active treatment at The Hospital for Sick Children (SickKids) in Toronto, Canada...
March 15, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28318637/impact-of-multiple-en-face-image-averaging-on-quantitative-assessment-from-optical-coherence-tomography-angiography-images
#20
Akihito Uji, Siva Balasubramanian, Jianqin Lei, Elmira Baghdasaryan, Mayss Al-Sheikh, SriniVas R Sadda
PURPOSE: To investigate the impact of multiple en face image averaging on quantitative measurements of the retinal microvasculature using optical coherence tomography angiography (OCTA). DESIGN: Prospective, observational, cross-sectional case series. PARTICIPANTS: Twenty-one healthy individuals with normal eyes. METHODS: Macular OCTA images were acquired from all participants using the Zeiss Cirrus 5000 with Angioplex OCTA software (Carl Zeiss Meditec, Dublin, CA)...
March 16, 2017: Ophthalmology
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