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JOURNAL ARTICLE
Jacqueline W Miller, Jessica A King, Katrina F Trivers, Machell Town, Susan A Sabatino, Mary Puckett, Lisa C Richardson
INTRODUCTION: Approximately 40,000 U.S. women die from breast cancer each year. Mammography is recommended to screen for breast cancer and reduce breast cancer mortality. Adverse social determinants of heath (SDOH) and health-related social needs (HRSNs) (e.g., lack of transportation and social isolation) can be barriers to getting mammograms. METHODS: Data from the 2022 Behavioral Risk Factor Surveillance System were analyzed to estimate the prevalence of mammography use within the previous 2 years among women aged 40-74 years by jurisdiction, age group, and sociodemographic factors...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
#2
JOURNAL ARTICLE
Ziqiang Li, Qingyong Hong, Kun Li
BACKGROUND: The relationship between lymph node (LN) status and survival outcome in hepatocellular carcinoma (HCC) is a highly controversial topic. The aim of this study was to investigate the prognostic factors in patients without LN metastasis (LNM) and to construct a nomogram to predict cancer-specific survival (CSS) in this group of patients. METHODS: We screened 6840 eligible HCC patients in the Surveillance, Epidemiology and End Results（SEER）database between 2010 and 2019 and randomized them into a training cohort and an internal validation cohort, and recruited 160 patients from Zhongnan Hospital of Wuhan University as an external validation cohort...
April 24, 2024: European Journal of Gastroenterology & Hepatology
#3
JOURNAL ARTICLE
David Cheng, Meghan L Rieu-Werden, Jacquelyn M Lykken, Claudia L Werner, Sarah Feldman, Michelle I Silver, Steven J Atlas, Jasmin A Tiro, Jennifer S Haas, Aruna Kamineni
BACKGROUND: Follow-up of abnormal results is essential to cervical cancer screening, but data on adherence to follow-up are limited. We describe patterns of follow-up after screening abnormalities and identify predictors of guideline-concordant follow-up. METHODS: We identified the index screening abnormality (positive human papillomavirus [HPV] test or atypical squamous cells of undetermined significance [ASC-US] or more severe cytology) among women 25-65 years old at three U...
April 23, 2024: Cancer Epidemiology, Biomarkers & Prevention
#4
JOURNAL ARTICLE
Andrew M Moon, Rachel M Swier, Lindsay M Lane, A Sidney Barritt, Hanna K Sanoff, Andrew F Olshan, Stephanie B Wheeler, George N Ioannou, Nicole J Kim, Scott Hagan, Philip Vutien, Thad Benefield, Louise M Henderson
BACKGROUND: Hepatocellular carcinoma (HCC) surveillance in patients with cirrhosis is associated with improved survival. Provision of HCC surveillance is low in the US, particularly in primary care settings. AIMS: To evaluate current hepatitis C virus (HCV) and HCC surveillance practices and physician attitudes regarding HCC risk-stratification among primary care and subspecialty providers. METHODS: Using the Tailored Design Method, we delivered a 34-item online survey to 7654 North Carolina-licensed internal/family medicine or gastroenterology/hepatology physicians and advanced practice providers in 2022...
April 23, 2024: Digestive Diseases and Sciences
#5
JOURNAL ARTICLE
Reza Darvishvand, Somayeh Rezaeifard, Razie Kiani, Sedigheh Tahmasebi, Zahra Faghih, Nasrollah Erfani
BACKGROUND: Natural killer (NK) cells, CD3- lymphocytes, are critical players in cancer immune surveillance. This study aimed to assess two types of CD3- NK cell classifications (subsets), that is, convectional subsets (based on CD56 and CD16 expression) and new subsets (based on CD56, CD27, and CD11b expression), and their functional molecules in the peripheral blood of patients with breast cancer (BC) in comparison with healthy donors (HDs). METHODS: Thirty untreated females with BC and 20 age-matched healthy women were enrolled...
April 2024: Immunity, Inflammation and Disease
#6
REVIEW
Maciej Gryziak, Leszek Kraj, Rafał Stec
Hepatocellular carcinoma is one of the most common cancers worldwide. Despite progress in treatment, recurrence after radical treatment is common, and the prognosis remains poor for patients with advanced disease. Therefore, there is a need to identify prognostic and predictive factors for the response to therapy or more intensive surveillance or treatment. Because the tumor microenvironment plays a crucial role in the development of cancer and metastasis, it is a crucial need to understand processes that are involved in carcinogenesis...
April 23, 2024: Journal of Gastroenterology and Hepatology
#7
JOURNAL ARTICLE
Govind S Bindra, David J Fei-Zhang, Atharva Desai, John Maddalozzo, Stephanie S Smith, Urjeet A Patel, Daniel C Chelius, Jill N D'Souza, Jeffrey C Rastatter, M Boyd Gillespie, Anthony M Sheyn
BACKGROUND: Salivary gland cancers (SGC)-social determinants of health (SDoH) investigations are limited by narrow scopes of SGC-types and SDoH. This Social Vulnerability Index (SVI)-study hypothesized that socioeconomic status (SES) most contributed to SDoH-associated SGC-disparities. METHODS: Retrospective cohort of 24 775 SGCs assessed SES, minority-language status (ML), household composition (HH), housing-transportation (HT), and composite-SDoH measured by the SVI via regressions with surveillance and survival length, late-staging presentation, and treatment (surgery, radio-, chemotherapy) receipt...
April 23, 2024: Head & Neck
#8
JOURNAL ARTICLE
Mark B Ulanja, Kwabena Oppong Asafo-Agyei, Vijay Neelam, Bryce D Beutler, Daniel Antwi-Amoabeng, Samuel B Governor, Ganiyu A Rahman, Francis T Djankpa, Reginald N Ulanja, Grace B Nteim, Tarig Mabrouk, Millicent Amankwah, Olatunji B Alese
BACKGROUND: Survival differences between left-sided colon cancer (LSCC) and right-sided colon cancer (RSCC) has been previously reported with mixed results, with various study periods not accounting for other causes of mortality. PURPOSE: We sought to assess the trends in colon cancer cause- specific survival (CSS) and overall survival (OS) based on sidedness. METHOD: Fine-Gray competing risk and Cox models were used to analyze Surveillance, Epidemiology, and End Results (SEER) population-based cohort from 1975 to 2019...
April 2024: Cancer Medicine
#9
JOURNAL ARTICLE
Aditi Dhir, Rachna Rahul, Qinran Liu, Dan Pham, Rachel Kronenfeld, Tulay Koru-Sengul, Paulo S Pinheiro
BACKGROUND: Ewing sarcoma (ES) is a malignant bone tumor most commonly affecting non-Hispanic White (NHW) adolescent males, though recognition among Hispanic individuals is rising. Prior population-based studies in the United States (US), utilizing Surveillance, Epidemiology, and End Results (SEER) have shown higher all-cause mortality among White Hispanics, Blacks, and those of low socioeconomic status (SES). Florida is not part of SEER but is home to unique Hispanic populations including Cubans, Puerto Ricans, South Americans that contrasts with the Mexican Hispanic majority in other US states...
April 2024: Cancer Medicine
#10
JOURNAL ARTICLE
Luana A Nurla, Ana-Maria Forsea
Every year in Europe over 150,000 new cases of melanoma are reported and over 25,000 lives are lost to this tumor. Incidence has been rising rapidly, faster than for any other cancer, and it is expected to continue to do so in most regions. Mortality also crept up, decades-long, with only few very recent exceptions. Thus, melanoma remains a public health problem that will not go away soon, nor easy. Some notable progress has been made in the last decade in the fight against this tumor. Registration and reporting for skin cancers improved across Europe...
April 2024: Italian journal of dermatology and venereology
#11
JOURNAL ARTICLE
Johan Stranne, Stefan Carlsson, Adalsteinn Gunnlaugsson, Jon Kindblom, Anna Lantz, Ola Bratt
There is a long history of curative treatment of prostate cancer. However, as prostate cancer often grows very slowly, and symptoms do not have time to develop during a person's lifetime, a more tentative approach has become more and more common in many cases. This may be through either watchful waiting or active surveillance. In the first case palliative hormonal treatment is given in the case of progression, in the latter curative treatment would be the choice. When treatment is deemed necessary for localized disease, surgery and radiotherapy are considered equivalent in terms of efficacy and overall risk of side effects...
April 22, 2024: Läkartidningen
#12
JOURNAL ARTICLE
Dan Huang, Minkyo Song, Sarah Krull Abe, Md Shafiur Rahman, Md Rashedul Islam, Eiko Saito, Katherine De la Torre, Norie Sawada, Akiko Tamakoshi, Xiao-Ou Shu, Hui Cai, Atsushi Hozawa, Seiki Kanemura, Jeongseon Kim, Yu Chen, Hidemi Ito, Yumi Sugawara, Sue K Park, Myung-Hee Shin, Mayo Hirabayashi, Takashi Kimura, Yu-Tang Gao, Wanqing Wen, Isao Oze, Aesun Shin, Yoon-Ok Ahn, Habibul Ahsan, Paolo Boffetta, Kee Seng Chia, Keitaro Matsuo, You-Lin Qiao, Nathaniel Rothman, Wei Zheng, Manami Inoue, Daehee Kang
BACKGROUND: The family history of gastric cancer holds important implications for cancer surveillance and prevention, yet existing evidence predominantly comes from case-control studies. We aimed to investigate the association between family history of gastric cancer and gastric cancer risk overall and by various subtypes in Asians in a prospective study. METHODS: We included 12 prospective cohorts with 550,508 participants in the Asia Cohort Consortium. Cox proportional hazard regression was used to estimate study-specific adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between family history of gastric cancer and gastric cancer incidence and mortality, then pooled using random-effects meta-analyses...
April 22, 2024: Gastric Cancer
#13
JOURNAL ARTICLE
Adom Bondzi-Simpson, Tiago Ribeiro, Angelo Grant, Michael Ko, Natalie Coburn, Julie Hallet, Girish S Kulkarni, Biniam Kidane
OBJECTIVE: Chemoradiation followed by esophagectomy is a standard treatment option for locally advanced esophageal cancer (LAEC) patients. Esophagectomy is a high-risk procedure, and recent evidence suggests select patients may benefit from omitting or delaying surgery. This study aims to compare surgery versus active surveillance for LAEC patients with complete clinical response (cCR) after neoadjuvant chemoradiotherapy (nCRT). METHODS: Decision analysis with Markov modelling was utilized...
April 20, 2024: Journal of Thoracic and Cardiovascular Surgery
#14
REVIEW
Ruihua Liu, Yawei Zhao, Shang Su, Augustine Kwabil, Prisca Chinonso Njoku, Haiquan Yu, Xiaohong Li
Tumor cells disseminate in various distant organs at early stages of cancer progression. These disseminated tumor cells (DTCs) can stay dormant/quiescent without causing patient symptoms for years or decades. These dormant tumor cells survive despite curative treatments by entering growth arrest, escaping immune surveillance, and/or developing drug resistance. However, these dormant cells can reactivate to proliferate, causing metastatic progression and/or relapse, posing a threat to patients' survival. It's unclear how cancer cells maintain dormancy and what triggers their reactivation...
April 20, 2024: Cancer Letters
#15
JOURNAL ARTICLE
Nathan VanderVeer-Harris, Zachary D Zippi, Dev P Patel, Murugesan Manoharan, Jorge R Caso, Georgeta D Vaidean
OBJECTIVE: In 2018, the United States Preventive Services Task Force promoted shared decision making between healthcare provider and patient for men aged 55 to 69. This study aimed to analyze rates of prostate-specific antigen (PSA) testing across racial and ethnic groups following this new recommendation. METHODS: A secondary analysis was conducted of the 2020-2021 Behavioral Risk Factor Surveillance System database to assess men aged 55 or older without a history of prostate cancer...
April 22, 2024: Journal of Medical Screening
#16
JOURNAL ARTICLE
Marcus A Quinn, Annie Reilly, Anne Pullyblank
AIM: Routine carcino-embryonic antigen blood testing is required after colorectal cancer resection, requiring face-to-face appointments. This has workforce implications, and impacts patients' lives. We assessed feasibility and acceptability of self-taken blood tests. METHODS: 50 colorectal cancer patients with experience of face-to-face phlebotomy surveillance agreed to self-testing finger-prick kits. Follow-up questionnaires assessed perspectives and preferences...
March 2024: Future Healthcare Journal
#17
Sajanakan Sriselvakumar, Louise Meehan
Testicular seminoma commonly occurs in young men aged between 15 and 45 years old. Those with testicular cancer may present with a lump or swelling in the testicle. If treated and managed early, patients can expect a greater than 95% success rate. However, advanced stages of testicular seminoma can lead to eventual metastasis. We present a 45-year-old male patient with a prior history of testicular seminoma who was admitted to the emergency department with abdominal distension and acute abdominal pain. The CT identified a rather sizable abdominal mass and the biopsy confirmed metastatic testicular seminoma...
July 2024: Radiology Case Reports
#18
JOURNAL ARTICLE
Siru Li, Jing Li, Qi Yang, Cunli Yin, Bin Liu
OBJECTIVE: To construct nomogram models to predict the risk factors for early death in patients with metastatic melanoma (MM). METHODS: The study covered 2138 cases from the Surveillance, Epidemiology, and End Results Program (SEER) database and all these patients were diagnosed with MM between 2010 and 2015. Logistic regression was performed to identify independent risk factors affecting early death in MM patients. These risk factors were then used to construct nomograms of all-cause early death and cancer-specific early death...
March 20, 2024: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
#19
JOURNAL ARTICLE
Ottavia De Simoni, Melania Scarpa, Ignazio Castagliuolo, Astghik Stepanyan, Imerio Angriman, Andromachi Kotsafti, Camilla Nacci, Federico Scognamiglio, Silvia Negro, Antonella D'Angelo, Valentina Chiminazzo, Gianluca Businello, Cesare Ruffolo, Roberta Salmaso, Boris Franzato, Mario Gruppo, Pierluigi Pilati, Antonio Scapinello, Anna Pozza, Tommaso Stecca, Marco Massani, Ivana Cataldo, Stefano Brignola, Angelo Paolo Dei Tos, Carlotta Ceccon, Vincenza Guzzardo, Chiara Vignotto, Luca Facci, Isacco Maretto, Marco Agostini, Francesco Marchegiani, Giulia Becherucci, Maurizio Zizzo, Giovanni Bordignon, Roberto Merenda, Giovanni Pirozzolo, Alfonso Recordare, Giulia Pozza, Mario Godina, Isabella Mondi, Daunia Verdi, Corrado Da Lio, Licia Laurino, Luca Saadeh, Giorgio Rivella, Silvio Guerriero, Chiara Romiti, Giuseppe Portale, Chiara Cipollari, Ylenia Camilla Spolverato, Giulia Noaro, Roberto Cola, Salvatore Candioli, Laura Gavagna, Fabio Ricagna, Monica Ortenzi, Mario Guerrieri, Giovanni Tagliente, Monica Tomassi, Umberto Tedeschi, Beatrice Salmaso, Gianluca Buzzi, Dario Parini, Daniela Prando, Matteo Zuin, Francesca Bergamo, Vittorina Zagonel, Andrea Porzionato, Francesco Cavallin, Barbara Di Camillo, Loretta Di Cristoforo, Quoc Riccardo Bao, Salvatore Pucciarelli, Romeo Bardini, Gaya Spolverato, Matteo Fassan, Marco Scarpa
BACKGROUND: Long-term daily use of aspirin reduces incidence and mortality due to colorectal cancer (CRC). This study aimed to analyze the effect of aspirin on the tumor microenvironment, systemic immunity, and on the healthy mucosa surrounding cancer. METHODS: Patients with a diagnosis of CRC operated on from 2015 to 2019 were retrospectively analyzed (METACCRE cohort). Expression of mRNA of immune surveillance-related genes (PD-L1, CD80, CD86, HLA I, and HLA II) in CRC primary cells treated with aspirin were extracted from Gene Expression Omnibus-deposited public database (GSE76583)...
April 22, 2024: Cancer
#20
JOURNAL ARTICLE
Liangyu Yin, Ling Zhang, Long Li, Ming Liu, Jin Zheng, Aiguo Xu, Quanjun Lyu, Yongdong Feng, Zengqing Guo, Hu Ma, Jipeng Li, Zhikang Chen, Hui Wang, Zengning Li, Chunling Zhou, Xi Gao, Min Weng, Qinghua Yao, Wei Li, Tao Li, Hanping Shi, Hongxia Xu
BACKGROUND: Body weight and its changes have been associated with cancer outcomes. However, the associations of short-term peridiagnosis weight dynamics in standardized, clinically operational time frames with cancer survival remain largely unknown. This study aimed to screen for and evaluate the optimal indicator of short-term peridiagnosis weight dynamics to predict overall survival (OS) in patients with cancer. METHODS: This multicentre cohort study prospectively collected data from 7460 patients pathologically diagnosed with cancer between 2013 and 2019...
April 21, 2024: Journal of Cachexia, Sarcopenia and Muscle
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