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Seborrheic keratosis

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https://www.readbyqxmd.com/read/28978228/an-unusual-childhood-mole-pigmented-basal-cell-cancer-mimicking-macular-seborrheic-keratosis
#1
Ramya Vangipuram, Kevin G Sharghi, Stephen K Tyring
No abstract text is available yet for this article.
October 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28947467/prevalence-and-associated-factors-of-skin-diseases-in-aged-nursing-home-residents-a-multicentre-prevalence-study
#2
Elisabeth Hahnel, Ulrike Blume-Peytavi, Carina Trojahn, Gabor Dobos, Irina Jahnke, Vera Kanti, Claudia Richter, Andrea Lichterfeld-Kottner, Natalie Garcia Bartels, Jan Kottner
OBJECTIVES: The aim of this study was to measure the prevalence of skin diseases in aged nursing home residents and to explore possible associations with demographic and medical characteristics. DESIGN: Descriptive multicentre prevalence study. SETTING AND PARTICIPANTS: The study was conducted in a random sample of ten institutional long-term care facilities in the federal state of Berlin, Germany. In total, n=223 residents were included. RESULTS: In total, 60 dermatological diseases were diagnosed...
September 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28937426/seborrheic-keratosis-with-prominent-clear-cell-changes-a-rare-but-important-diagnostic-variant
#3
Thomas H Long, David Zlotnick, Stanley L Hurst, Zsolt Argenyi
Seborrheic keratoses, although exceedingly common, occasionally have morphologic similarities to other lesions that complicate a typically straightforward diagnosis. The authors present a case of a 69-year-old man with a left shoulder lesion that displayed characteristic clinical and microscopic features of seborrheic keratosis on biopsy. However, diffuse and prominent clear cells were also noted. These stained strongly with Periodic acid-Schiff and were diastase sensitive, suggestive of glycogen accumulation and possible trichilemmal differentiation...
September 12, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28932054/darier-disease-a-rare-genodermatosis
#4
Hema Suryawanshi, Akshay Dhobley, Aparna Sharma, Pramod Kumar
Darier disease (DD), also known as keratosis follicularis or dyskeratosis follicularis, is a rare autosomal dominant genodermatosis with high penetrance and variable expressivity. It is caused by mutations of ATP2A2 gene which encodes the sarco/endoplasmic reticulum Ca(2+) ATPase isoform 2. It is clinically manifested by hyperkeratotic papules primarily affecting seborrheic areas on the head, neck and thorax, with less frequent involvement of the oral mucosa. When oral manifestations are present, they primarily affect the palatal and alveolar mucosa, are usually asymptomatic and are discovered in routine dental examination...
May 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28916031/dermatosis-papulosa-nigra-a-clinically-and-histopathologically-distinct-entity
#5
Simon Arda Metin, Brian W Lee, William Clark Lambert, Lawrence Charles Parish
Dermatosis papulosa nigra was first described by Aldo Castellani (1874-1971) more than 90 years ago, and it has since been presumed to be a variant of seborrheic keratosis. Despite their morphologic similarities both macroscopically and microscopically, key differences have yet to be explained. These lesions also exhibit different demographics, with dermatosis papulosa nigra having a predilection for dark-skinned individuals and a female predominance. No studies to date have investigated this, but studies assessing the mechanisms of similar dermatologic conditions may yield significant clues...
September 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28915278/differential-diagnosis-of-seborrheic-keratosis-clinical-and-dermoscopic-features
#6
Ralph P Braun, Sabine Ludwig, Ashfaq A Marghoob
<p>Seborrheic keratosis (SK) is a benign epidermal keratinocytic tumor that is extremely common, particularly in individuals over the age of 50. Most individuals with SK will have more than one lesion and the presence of over 10 lesions in the same person is not uncommon. Although the clinical morphology of most SK with their stuck-on, symmetric, keratotic, and waxy appearance makes them easy to identify, many manifest a morphology resembling melanoma or squamous cell carcinoma. One can argue that such cases will ultimately not prove to be problematic since a simple biopsy will easily reveal their benign nature and eliminate any concerns...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28913302/eccrine-poroma-of-the-postauricular-area
#7
Hyun Rok Lee, Gyu Yong Jung, Hea Kyeong Shin, Dong Lark Lee, Jong Im Lee, Jung Hwan Kim
Eccrine poroma is a common benign cutaneous tumor that originates in an intraepidermal eccrine duct. This tumor exhibits acral distribution (sole, palm), and is rarely encountered in the head and neck area. In fact eccrine poroma in the postauricular area has only been rarely reported. A 55-year-old female visited our hospital with a main complaint of a mass that first developed in the left postauricular area about a year previously. The mass was painless, soft, protruding, domed, and dark red in color, and had slowly enlarged (at presentation it measured 1×1 cm)...
March 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28902028/a-101-a-proprietary-topical-formulation-of-high-concentration-hydrogen-peroxide-solution-a-randomized-double-blind-vehicle-controlled-parallel-group-study-of-the-dose-response-profile-in-subjects-with-seborrheic-keratosis-of-the-face
#8
Janet C DuBois, Michael Jarratt, Brian B Beger, Mark Bradshaw, Christopher V Powala, Stuart D Shanler
BACKGROUND: Seborrheic keratosis (SK) is a common benign skin tumor, yet no topical treatments are approved in the United States. OBJECTIVE: To evaluate the proprietary, stabilized, high-concentration hydrogen peroxide-based topical solution A-101 (32.5% and 40% concentrations) for treatment of facial SK lesions. MATERIALS AND METHODS: In this multicenter, double-blind, vehicle-controlled study, eligible subjects were randomly assigned to receive up to 2 treatments of A-101 40%, A-101 32...
September 4, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28857272/acanthoma-planoepitheliale-hyperkeratoticum-lesions-associated-with-braf-inhibitor-in-metastatic-melanoma
#9
M Sokołowska-Wojdyło, B Olszewska, M Sobjanek, M Sławińska, K Sosińska-Mielcarek, W Biernat, R Nowicki
A 68-year-old woman was diagnosed with BRAF V600 mutation positive melanoma of unknown primary (MUP) with metastasis to the lung, liver and brain. According to local standards dabrafenib monotherapy was started in July 2016. Control CT performed after two months revealed disease stabilization. The tolerance of therapy was good, but after 2 months of treatment with dabrafenib the patient developed disseminated skin lesions with extended seborrheic keratosis G2 (according to international common toxicity criteria CTC)...
August 30, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28832993/what-s-new-in-dermoscopy-of-bowen-s-disease-two-new-dermoscopic-signs-and-its-differential-diagnosis
#10
Yi Yang, Jingrong Lin, Shifeng Fang, Shixin Han, Zhiqi Song
BACKGROUND: Clinical and dermoscopic features of Bowen's disease (BD) show great diversity. Some lesions of BD are often difficult to be differentiated from seborrheic keratosis, actinic keratosis, lichen planus-like keratosis, etc. It is necessary to fully describe the dermoscopic features of the disease, considering differential diagnosis. OBJECTIVE: To describe the dermoscopic feautres of Bowen's disease and summarize the dermoscopic differential diagnosis of the disease...
October 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28761291/various-dermatoses-what-the-patients-with-cutaneous-melanoma-had-anxiety-for-the-recurrence-during-postoperative-surveillance
#11
Hyun-Joo Lee, Hyunju Jin, Hyang-Suk You, Woo-Haing Shim, Jeong-Min Kim, Gun-Wook Kim, Je-Ho Mun, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim
BACKGROUND: The incidence and mortality rates associated with cutaneous melanoma (CM) have steadily increased over the last 20 years. Even with successful treatment, melanoma patients usually experience substantial anxiety regarding the development of terrible recurrence. To date, few studies have investigated various dermatoses what the patients with CM had anxiety for the recurrence during postoperative surveillance (Dw). OBJECTIVE: To describe various Dw and to evaluate the risk of subsequent malignant skin disease in patients with CM...
August 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28730249/sebaceoma-associated-with-seborrheic-keratosis
#12
Angel Fernandez-Flores, José Antonio Manjón
Sebaceoma associated with seborrheic keratosis has only been described once in the literature. Herein, we present an additional case in a 69-year-old woman who complained of a multicolored plaque on the left breast. Dermatoscopy showed a central orange lesion with orange globules suggestive of dilated glands. The periphery of the lesion was brown and gray, with some more pigmented zones. The histopathological study demonstrated a seborrheic keratosis in the peripheral areas, whereas the central part of the lesion was a sebaceoma...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28667573/urologic-dermatology-a-review
#13
REVIEW
Andrew W Stamm, Kathleen C Kobashi, Ksenija B Stefanovic
PURPOSE OF REVIEW: Genital dermatology represents a challenge to many providers. Though dermatologic lesions involving the genitalia may present to any of a number of practices, ranging from primary care to urology, gynecology, and dermatology, few training programs provide significant training regarding the diagnosis and management of genital dermatologic lesions. The purpose of this review is to provide urologists with an overview of common genital dermatological lesions that may be encountered in a clinic...
August 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28589622/cutaneous-malignancies-simulating-seborrheic-keratoses-an-underappreciated-phenomenon
#14
Tiffany Y Chen, Annie O Morrison, Clay J Cockerell
BACKGROUND: Seborrheic keratosis (SK), a common and benign entity, is generally diagnosed clinically without the need for a biopsy. Given their variable appearance, SK may mimic cancer clinically and require biopsy for clinically equivocal cases. A clinician may also choose to perform biopsies on SK based on other circumstances, such as cosmetic reasons or SK being in an inconvenient and irritative location. METHODS: Dermatopathology samples from 2015 obtained from private and university locations were retrospectively assessed...
June 7, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28578364/xeroderma-pigmentosum-at-a-tertiary-care-center-in-saudi-arabia
#15
Lenah Alwatban, Yousef Binamer
BACKGROUND: Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder caused by defective DNA repair that results in extreme sensitivity to ultraviolet (UV) rays. Depending on the type of XP, the disease may affect the skin, eyes and nervous system. OBJECTIVES: Describe the dermatologic manifestations in patients suffering from XP. DESIGN: Retrospective, descriptive review of medical records. SETTING: Dermatology clinic at tertiary care center in Riyadh...
May 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28562437/use-of-skin-biopsies-among-dermatologists
#16
David A Weinstein, Sasank Konda, Brett M Coldiron
BACKGROUND: Skin biopsies are essential to establish a diagnosis in many skin diseases. Utilization has been increasing rapidly and represents a significant health care cost. There are no benchmarks or baselines to guide the practice of skin biopsies. OBJECTIVE: To create a reference data set of biopsy behavior among dermatologists. METHODS: Five hundred eighty-eight dermatologists belonging to the American Dermatological Association (ADA) were surveyed...
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28541873/an-unusual-presentation-of-seborrheic-keratoses-in-a-man-with-hereditary-hemochromatosis
#17
Tiffany Y Loh, Philip R Cohen
Hereditary hemochromatosis is an autosomal recessive disorder that disturbs iron metabolism and results in iron deposition throughout the body. Iron accumulation in various organs may cause a wide range of systemic symptoms and cutaneous manifestations of the disease are particularly striking. Classically, hereditary hemochromatosis has been termed "bronze diabetes." Although diffuse hyperpigmentation is a well-described feature of this disease, other cutaneous symptoms may also occur, and a variety of anomalies may be observed...
April 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28515993/triage-amalgamated-dermoscopic-algorithm-tada-for-skin-cancer-screening
#18
Tova Rogers, Maria Marino, Stephen W Dusza, Shirin Bajaj, Michael A Marchetti, Ashfaq Marghoob
IMPORTANCE: Dermoscopic triage algorithms have been shown to improve beginners' abilities for identifying pigmented skin lesions requiring biopsy. OBJECTIVE: To estimate the diagnostic accuracy of the Triage Amalgamated Dermoscopic Algorithm (TADA) for pigmented and nonpigmented skin cancers. Secondarily, to compare TADAs performance to those of existing triage algorithms for the identification of pigmented skin cancers. DESIGN: Cross-sectional, observational, reader study that took place at a beginner and intermediate level dermoscopy course...
April 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/28488240/erratum-to-increasing-frequency-of-seborrheic-keratosis-diagnoses-as-a-favorable-consequence-of-teledermatology-based-skin-cancer-screening-a-cross-sectional-study-of-34-553-patients
#19
David Moreno-Ramírez, Jesús Raya-Maldonado, Macarena Morales-Conde, Teresa Ojeda-Vila, Francisco J Martín-Gutiérrez, Andrés Ruíz-de-Casas, Almudena Fernández-Orland, Juan M Herrerías-Esteban, Lara Ferrándiz
No abstract text is available yet for this article.
May 9, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28475506/clonal-seborrheic-keratosis-versus-pagetoid-bowen-disease-histopathology-and-role-of-adjunctive-markers
#20
Inchara Yeliur Kalegowda, Almut Böer-Auer
Clonal seborrheic keratosis (CSK) and pagetoid Bowen disease (squamous cell carcinoma in situ) (PBD) share similar histological features making it sometimes difficult to differentiate the 2. The study group included 29 and 13 cases of CSK and PBD, respectively. Both groups were examined histopathologically (suprabasal mitotic figures, broad rete ridges, crowding of nuclei, nuclear pleomorphism, necrotic keratinocytes, parakeratosis, and dermal inflammation) and immunohistochemically (CK10, Ki-67, and p16). P values for all parameters were calculated using Fisher exact test, 2 tailed...
June 2017: American Journal of Dermatopathology
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