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Seborrheic keratosis

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https://www.readbyqxmd.com/read/27922892/galectin-3-expression-in-benign-and-malignant-skin-diseases-with-epidermal-hyperplasia
#1
Ze-Xin Jiang, Guo-Zhen Tan, Zhen-Rui Shi, Yu-Ping Zhang, Yan-Fang Han, Liangchun Wang
Galectin-3 has been suggested relative to tumor genesis, progression, and metastasis in basal cell carcinoma and squamous cell carcinoma that are the most common skin cancers characterized by malignant epidermal proliferation. In this study, we evaluated galectin-3 expression in seborrheic keratosis, keratoacanthoma, and infectious diseases including verruca vulgaris, condyloma acuminatum, and chromoblastomycosis that are pathologically featured by benign epidermal proliferation. Galectin-3 expression was shown by immunohistochemical staining and quantified using the Image Pro Plus V6...
November 7, 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27904179/a-clinicopathological-and-dermoscopic-correlation-of-seborrheic-keratosis
#2
Geethu Francis Alapatt, D Sukumar, M Ramesh Bhat
BACKGROUND: Seborrheic keratosis (SK) is the most common benign epidermal tumor of the skin. Even though SK has been well characterized clinically, dermoscopically, and histopathologically, data regarding clinical dermoscopic and histopathological correlation of different types of SK are inadequate. AIM: We carried out this study to establish any correlation between the clinical, dermoscopic, and histopathological appearance of SK and its variants. METHODS: This was a descriptive study...
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27888829/treatment-of-seborrheic-keratosis-in-bilateral-external-auditory-canal-using-fiber-co2-laser
#3
Raşit Cevizci, Selin Üstün Bezgin, Gökhan Altın, Gülbin Oran, Yıldırım Ahmet Bayazıt
In this article, we report a 33-year-old female patient with lesions of bilateral external auditory canals who was treated using fiber CO2 laser without canaloplasty. Histopathological examination confirmed the diagnosis of irritated type seborrheic keratosis, which is rare in external auditory canal. Twelve months after the treatment, the patient showed no signs of recurrence.
September 2016: Kulak Burun Boğaz Ihtisas Dergisi: KBB, Journal of Ear, Nose, and Throat
https://www.readbyqxmd.com/read/27867748/pigmented-bowen-s-disease-presenting-with-a-starburst-pattern
#4
Vincenzo Maione, Enzo Errichetti, Sara Laurent Roussel, Celeste Lebbé
Pigmented Bowen's disease (pBD) is an uncommon in situ squamous cell carcinoma of the skin usually presenting as a dark scaly plaque involving chronically exposed sites, which is not uncommonly mistaken for other similar pigmented lesions, such as melanoma, pigmented basal cell carcinoma or seborrheic keratosis [1,2]. Dermoscopy has been proven to improve its diagnosis by showing several findings, i.e., gray/brownish dots in linear arrangement, scales, coiled vessels, focal/multifocal amorphous hypopigmentation and bluish structureless areas [1,2]...
October 2016: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/27867743/in-vivo-reflectance-confocal-microscopy-features-of-a-melanoacanthoma
#5
Neda Shahriari, Jane M Grant-Kels, Harold S Rabinovitz, Margaret Oliviero, Alon Scope
Efforts have been expended to evaluate the reflectance confocal microscopy (RCM) features of different clinical entities in order to more thoroughly delineate benign versus malignant features. In this way, RCM can help clinicians to be more selective in regard to undertaking appropriate skin biopsies and improving their benign to malignant ratio. Herein, we report a case of a histopathologically proven melanoacanthoma, a variant of seborrheic keratosis. There are scarce reports describing the RCM features of melanoacanthoma...
October 2016: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/27811637/cutaneous-horn-of-the-eyelid-in-13-cases
#6
Renelle Pointdujour-Lim, Molly R Marous, Celine E Satija, Alexzandra M Douglass, Ralph C Eagle, Jerry A Shields, Carol L Shields
INTRODUCTION: Cutaneous horn of the eyelid is uncommon. The authors evaluate the features of benign, premalignant, and malignant tumors at the base of cutaneous horn of the eyelid. OBJECTIVE: To describe the clinical and histopathologic features of cutaneous horn of the eyelid. DESIGN: A retrospective analysis of 13 cases of cutaneous horn of the eyelid treated between 1994 and 2014 was performed. PARTICIPANTS: Thirteen patients participated in this study...
November 2, 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27792064/seborrheic-keratosis-like-lesions-of-the-cervix-and-vagina-report-of-a-new-entity-possibly-related-to-low-risk-human-papillomavirus-infection
#7
Karen L Talia, W Glenn McCluggage
We report a series of 7 unusual and morphologically distinct cervical or upper vaginal lesions in women aged 41 to 70 years. The lesions involved the cervix in 3 cases, the upper vagina in 2, the cervix and vagina in 1, and in 1 case the site of origin could not be determined. The lesions had a consistent morphologic appearance with a surface "plaque-like" or "stuck-on" configuration apparent in those cases where surrounding normal tissues were present. Broad coalescing solid sheets and interconnecting trabeculae of cytologically bland cells with a rather "basaloid" appearance emanated from the surface and there were scattered squamous eddies...
October 27, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27790747/two-cases-of-seborrheic-keratosis-with-basal-clear-cells
#8
Takashi Anan, Takaya Fukumoto, Tetsunori Kimura
Seborrheic keratosis with basal clear cells (SKBCC) is an extremely rare histopathological variant of seborrheic keratosis that has histological similarities to melanoma in situ. We herein report two cases of SKBCC and provide the first description of the dermoscopic features of this condition, in addition to the histopathological findings. Both of the two lesions showed typical histological architectures of seborrheic keratosis with rows or focal clusters of monomorphic clear cells with abundant pale cytoplasm and small round nucleus in the basal layer...
October 28, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27593207/exposure-to-fine-particulate-matter-associated-with-senile-lentigo-in-chinese-women-a-cross-sectional-study
#9
F Peng, C-H Xue, S K Hwang, W-H Li, Z Chen, J-Z Zhang
BACKGROUND: Skin ageing especially senile lentigo directly affects self-esteem. For decades, senile lentigo has been associated with chronic exposure to solar radiation. However, a study conducted recently in Caucasian subjects suggested that exposure to air pollution was significantly correlated with extrinsic skin ageing, in particular senile lentigines. OBJECTIVE: To investigate the association between fine particulate matter (PM2.5 ) and skin ageing, particularly senile lentigo and seborrheic keratosis...
September 5, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27578084/paraneoplastic-itch-management
#10
Brandon Rowe, Gil Yosipovitch
Paraneoplastic itch occurs as the result of a systemic reaction to an underlying malignancy. Paraneoplastic itch is most commonly associated with lymphoproliferative malignancies and solid tumors that result in cholestasis. Paraneoplastic itch may occur in the absence of a primary rash or in association with dermatologic conditions such as erythroderma, acanthosis nigricans, dermatomyositis, Grover's disease, and eruptive seborrheic keratosis. Treatment of paraneoplastic itch is centered on targeting the underlying malignancy responsible for the systemic reaction...
2016: Current Problems in Dermatology
https://www.readbyqxmd.com/read/27565032/indole-3-acetic-acid-photodynamic-therapy-in-the-treatment-of-multiple-actinic-keratoses-a-proof-of-concept-pilot-study
#11
Vieri Grandi, Irene Baldi, Pietro Cappugi, Moira Mori, Nicola Pimpinelli
BACKGROUND: Actinic Keratoses (AK) are considered a form of in situ Squamous Cell Carcinoma (SCC) arising on chronically photoexposed skin. PDT with ALA or MAL is an effective treatment for multiple AK due its high Overall Response Ratio (ORR) but is burdened by important drawbacks: time-consumption, pain and high costs. Indole-3 acetic acid (IAA) is a newly described photosensitizer with proven clinical efficacy on seborrheic dermatitis and acne vulgaris. The aim of the study was to assess efficacy, safety and tolerability of a cycle of IAA-PDT at 0...
August 23, 2016: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/27512194/nodulocystic-basal-cell-carcinoma-arising-directly-from-a-seborrheic-keratosis-a-rare-case-report
#12
Kana Shibao, Naoko Okiyama, Ryota Tanaka, Hitoshi Maruyama, Yasuhiro Fujisawa, Manabu Fujimoto
Seborrheic keratoses (SKs) are common epidermal tumors composed of benign keratinocytes. Malignant skin tumors including basal cell carcinoma (BCC) rarely arise within SKs. We report a rare case of an 82-year-old man with nodulocystic BCC that appeared at the center of a scaly hyperpigmented SK that had been presented for more than 10 years. It was histologically confirmed that CK19-positive BCC arose directly from the wall of the pseudohorn cyst, a part of the SK. Nodular and/or cystic BCC also rarely arise within SKs while the most common histologic type of BCC within SKs is the superficial type...
July 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27477176/dermatoscopic-findings-of-seborrheic-keratosis-in-melanoma
#13
Maria Luiza Brandão, Cíntia Maria Oliveira Lima, Heloísa Helena Moura, Cleide Ishida, Gabriella Campos-do-Carmo, Tullia Cuzzi, Marcia Ramos-E-Silva
Cutaneous melanoma may in some instances be confused with seborrheic keratosis, which is a very common neoplasia, more often mistaken for actinic keratosis and verruca vulgaris. Melanoma may clinically resemble seborrheic keratosis and should be considered as its possible clinical simulator. We report a case of melanoma with dermatoscopic characteristics of seborrheic keratosis and emphasize the importance of the dermatoscopy algorithm in differentiating between a melanocytic and a non-melanocytic lesion, of the excisional biopsy for the establishment of the diagnosis of cutaneous tumors, and of the histopathologic examination in all surgically removed samples...
June 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27438205/dermatofibroma-simulating-seborrheic-keratosis-dermoscopically
#14
Daniel Holanda Barroso, Camila Pinon Zoby Leite, Gabriela Diniz de Souza Araujo, Márcia Almeida Galvão Teixeira, Eliane Ruth Barbosa Alencar, Silvana Maria de Morais Cavalcanti
Dermatofibroma is a frequent benign tumor of easy clinical diagnosis in most cases, but that can mimic other dermatoses. Dermoscopy may help to define the diagnosis and its classical pattern is a central white area, similar to a scar, surrounded by a discrete pigment network. However, dermoscopic findings are not always typical. We describe here a case of dermatofibroma exhibiting ridges, furrows and pseudocomedos, a pattern which is typical of seborrheic keratosis, in dermoscopy.
May 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27331234/cells-to-surgery-quiz-march-2016
#15
Vidhi V Shah, Adam S Aldahan, Stephanie Mlacker, Sahal Samarkandy, Amr Molla, Keyvan Nouri
No abstract text is available yet for this article.
March 2016: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/27326718/image-analysis-for-quantification-of-nucleolar-organizer-regions-in-basal-cell-carcinoma-and-seborrheic-keratosis
#16
S Y Lee, J S Lee, C H Oh
BACKGROUND/AIMS: Nucleolar organizer regions (NORs) have recently attracted much attention because of claims that their frequency within nuclei is significantly higher in malignant cells than in normal, reactive, or benign neoplastic cells. The purpose of this paper is to analyze a method allowing selection of the best morphometric criterion for quantifying AgNORs (Silver stained Nucleolar organizer Regions) under conventional observation conditions, by light microscopy. METHODS: The various parameters including NORs counting in cutaneous tumors using image analysis system were studied...
November 1995: Skin Research and Technology
https://www.readbyqxmd.com/read/27317533/pigmented-seborrheic-keratosis-showing-starburst-pattern
#17
Akane Minagawa, Masaru Tanaka, Hiroshi Koga, Ryuhei Okuyama
No abstract text is available yet for this article.
July 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27303152/a-case-of-melanoacanthoma-immunohistochemical-staining-using-vector%C3%A2-novared%C3%A2-to-distinguish-melanocytes-from-the-cutaneous-pigment
#18
Jae Eun Choi, Eui Jong Bae, Ae Ree Kim, Sang Wook Son, Hae Jun Song, Chil Hwan Oh
Melanoacanthoma is a rare benign mixed tumor of both keratinocytes and melanocytes. Although some authors said that it is a rare variant of seborrheic keratosis, it has clinical and histological features distinct from seborrheic keratosis. It has large dendritic melanin-laden melanocytes throughout all levels of epidermis showing a disruption of melanin transfer from the melanocytes to neighboring keratinocytes. However, it is difficult to distinguish melanocytes clearly from cutaneous pigment in immunohistochemical stain with usually used brown chromogen...
March 2008: Annals of Dermatology
https://www.readbyqxmd.com/read/27294065/diclofenac-gel-may-be-a-new-treatment-option-for-seborrheic-keratosis
#19
Habibullah Aktaş, Can Ergin, Havva Özge Keseroğlu
No abstract text is available yet for this article.
May 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27294052/inverted-follicular-keratosis-successfully-treated-with-imiquimod
#20
Ayse Serap Karadag, Emin Ozlu, Tugba Kevser Uzuncakmak, Necmettin Akdeniz, Bengu Cobanoglu, Berkant Oman
Inverted follicular keratosis is a rare benign tumor of the follicular infundibulum characterized by exo-endophytic growing. It is thought to be a rare variant of the seborrheic keratosis. The diagnosis of inverted follicular keratosis is generally established histopathologically because clinical differentiation from other lesions is difficult. Herein, we present one such rare case, successfully treated with topical 5% imiquimod cream.
May 2016: Indian Dermatology Online Journal
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