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https://www.readbyqxmd.com/read/28918588/a-practical-approach-to-managing-hypoactive-sexual-desire-disorder-in-women-with-diabetes
#1
REVIEW
Charmaine Rochester-Eyeguokan, Lisa Meade
Female sexual dysfunction (FSD) is highly prevalent in women with diabetes mellitus (DM), yet it remains unaddressed, undiagnosed, and untreated. Hypoactive sexual desire disorder (HSDD) is the most common complaint among women with FSD, but there is a paucity of research into its multifactorial etiology. Flibanserin is the only therapy approved by the US Food and Drug Administration for treating acquired, generalized HSDD in premenopausal women. Women with DM diagnosed with HSDD may require a multidisciplinary approach for optimal management...
September 16, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28911977/screening-for-sexual-dissatisfaction-among-people-with-type-2-diabetes-in-primary-care
#2
Anne Bijlsma-Rutte, Annemarie M J Braamse, Patricia van Oppen, Frank J Snoek, Paul Enzlin, Peter Leusink, Giel Nijpels, Petra J M Elders
AIMS: The identification and discussion of sexual care needs in people with type 2 diabetes mellitus (T2DM) in primary care is currently insufficient. The objective of this study was to determine the prevalence of sexual dissatisfaction, sexual problems and need for help by using a screening instrument among people with T2DM in primary care. METHODS: Data were collected in 45 general practices in the Netherlands from January 2015 to February 2016. The Brief Sexual Symptom Checklist (BSSC) was used to screen among 40-75 year old men and women...
August 4, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28893567/molecular-basis-of-androgen-action-on-human-sexual-desire
#3
REVIEW
Daniele Santi, Giorgia Spaggiari, Lisa Gilioli, Francesco Potì, Manuela Simoni, Livio Casarini
Reproduction is a fundamental process for the species maintenance and the propagation of genetic information. The energy expenditure for mating is overtaken by motivational stimuli, such as orgasm, finely regulated by steroid hormones, gonadotropins, neurotransmitters and molecules acting in the brain and peripheral organs. These functions are often investigated using animal models and translated to humans, where the androgens action is mediated by nuclear and membrane receptors converging in the regulation of both long-term genomic and rapid non-genomic signals...
September 8, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28885410/distressing-sexual-function-at-midlife-unmet-needs-practical-diagnoses-and-available-treatments
#4
James A Simon, Vanessa A Lukas
Female sexual dysfunction (FSD) is characterized as chronic sexual symptoms that manifest with personal distress in the domains of desire, arousal, orgasm, and pain. Extensive epidemiologic evidence estimates that almost 50% of perimenopausal and postmenopausal women experience FSD. Screening for FSD is not readily conducted and patient-physician discussion of sexuality is limited by the lack of physician training on the topic and by the patient-held belief that sexual issues are not medical in nature. The purpose of this commentary is to provide clinicians with a framework to approach the discussion of FSD, to clinically identify FSD through patient symptoms and physical signs, and to manage FSD in perimenopausal and postmenopausal patients with the available U...
September 5, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28873063/a-descriptive-cross-sectional-study-to-assess-quality-of-life-and-sexuality-in-turkish-patients-with-a-colostomy
#5
Emel Yilmaz, Dilruba Çelebi, Yavuz Kaya, Hakan Baydur
A stoma affects personality, self-esteem, and body image, inevitably impacting lifestyle and quality of life (QOL). A descriptive, cross-sectional study was conducted between May 1, 2015 and May 1, 2016 to evaluate the effect of a stoma on sexual function and QOL among patients receiving care in a general surgery clinic of a university hospital in the western region of Turkey.Eligibility requirements included patients willing to participate, >18 years of age, with a colostomy for at least 4 months, who were married and/or with a sexual partner and in otherwise good physical and mental health with no rectal nerve damage or receiving radio- or chemotherapy...
August 2017: Ostomy/wound Management
https://www.readbyqxmd.com/read/28871716/the-influence-of-eruca-sativa-arugula-on-pharmacokinetics-of-sildenafil-in-rats
#6
Eyad Mallah, Soadad Saleh, Walid Abu Rayyan, Wael Abu Dayyih, Feras Darwish Elhajji, Mohammed Mima, Riad Awad, Tawfiq Arafat
OBJECTIVES: A drug like Sildenafil is commonly used for the treatment of erectile dysfunction. Eruca sativa is known as a garden plant used in folk medicine to enhance the sexual desire in males. Nevertheless, the interaction of Sildenafil and Eruca sativa was not studied. In the current study, we aimed to examine the influence of Eruca sativa on Sildenafil pharmacokinetics in rats. STUDY DESIGN: A crossover experiment with washout period of two weeks was conducted...
August 5, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28868819/erectile-dysfunction-in-men-with-and-without-lower-urinary-tract-symptoms-in-nigeria
#7
Patrick Temi Adegun, Peter Olufemi Areo, Abidemi Solomon, Samuel Ayokunle Dada, Philip Babatunde Adebayo
PURPOSE: Much attention has been focused in recent decades on the effects of erectile dysfunction (ED) secondary to lower urinary tract symptoms (LUTS), potentially underestimating its effects in men without LUTS. This study aimed to compare the prevalence and predictors of ED in men with and without LUTS. MATERIALS AND METHODS: The International Index of Erectile Function questionnaire was administered to 303 patients between January 2014 and June 2016. Within this sample, 147 patients with LUTS (cases) were compared to 156 men without LUTS who were matched for age, level of education, and occupation (controls)...
August 2017: World Journal of Men's Health
https://www.readbyqxmd.com/read/28867561/depressive-symptoms-and-low-sexual-desire-after-radical-prostatectomy-early-and-long-term-outcomes-in-a-real-life-setting
#8
Luca Boeri, Paolo Capogrosso, Eugenio Ventimiglia, Walter Cazzaniga, Filippo Pederzoli, Giorgio Gandaglia, Nadia Finocchio, Federico Dehò, Alberto Briganti, Emanuele Montanari, Francesco Montorsi, Andrea Salonia
PURPOSE: To assess the rate of and predictors of depressive symptoms (DS) and sexual desire (SD) impairment in patients who underwent either open (ORP) or robot-assisted (RARP) radical prostatectomy. MATERIALS AND METHODS: 811 patients completed the International Index of Erectile Function (IIEF) and the Beck's Inventory for Depression (BDI) preoperatively and at 6, 12, 24 and 36 months post surgery. Rates and predictors of DS and SD impairment were assessed with descriptive statistics and logistic regression models...
August 31, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28865901/neuroimaging-of-female-sexual-desire-and-hypoactive-sexual-desire-disorder
#9
REVIEW
Stephanie Cacioppo
INTRODUCTION: Recent advances in neuroimaging offer an unprecedented window into the female sexual brain. The small samples and poor statistical power of individual functional magnetic resonance imaging studies have limited what can be gleaned about the systematic brain network that is involved in female sexual desire and female sexual dysfunction (eg, hypoactive sexual desire disorder [HSDD]). AIM: To quantitatively determine the brain network involved in HSDD...
August 30, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28858028/prevalence-of-sexual-symptoms-in-relation-to-menopause-in-women-in-asia-a-systematic-review
#10
Rakibul M Islam, Robin J Bell, Susan R Davis
OBJECTIVE: This systematic review of the literature was undertaken to investigate the prevalence of sexual symptoms in women in Asia in relation to their menopause status. METHODS: MEDLINE, EMBASE, PsycINFO, CINAHL, SCOPUS, and Google scholar were searched systematically for relevant population-based prevalence studies published between 1988 and 2016. The included studies were assessed for risk of bias using a risk-of-bias tool developed explicitly for the systematic review of prevalence studies...
August 28, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28854893/self-reported-sexual-health-breast-cancer-survivors-compared-to-women-from-the-general-population-an-observational-study
#11
Anne Oberguggenberger, Caroline Martini, Nathalie Huber, Lesley Fallowfield, Michael Hubalek, Martin Daniaux, Barbara Sperner-Unterweger, Bernhard Holzner, Monika Sztankay, Eva Gamper, Verena Meraner
BACKGROUND: Cancer survivorship is of increasing importance in post-treatment care. Sexual health (SH) and femininity can be crucial issues for women surviving cancer. We aimed to determine a more complete understanding of the contribution that a breast cancer (BC) diagnosis and its treatment exert on patients' follow-up SH. For this purpose, self-reported levels and predictors of SH in breast cancer survivors (BCS) were compared with those of women with no previous or current BC (WNBC)...
August 30, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28845463/contraceptive-vaginal-ring-experiences-among-women-and-men-in-kisumu-kenya-a-qualitative-study
#12
E McLellan-Lemal, K Ondeng'e, D A Gust, M Desai, F O Otieno, P A Madiega, B Nyagol, E M Makanga
BACKGROUND: Future HIV prevention options for women will likely include Antiretroviral (ARV)-based intravaginal rings. Valuable insights may be gained by examining user experiences with a similar licensed technology, a contraceptive ring, especially in settings where this technology may not be currently available. METHODS: In-depth interviews with 24 females enrolled in a trial assessing acceptability and use of a contraceptive ring, and 20 male sexual partners were conducted September 2014-April 2015...
March 2017: Frontiers in Women's Health
https://www.readbyqxmd.com/read/28841367/knowledge-attitude-and-experience-of-health-professionals-of-female-genital-mutilation-fgm-a-qualitative-study-in-iraqi-kurdistan-region
#13
Nazar P Shabila, Hamdia M Ahmed, Kolsoom Safar
We aimed to assess the knowledge, attitude, and experience of health professionals of female genital mutilation (FGM). The study involved content analysis of semi-structured interviews with 21 health professionals. The participants had poor knowledge regarding different aspects of FGM including its types, prevalence, and complications as well as the existing legislation which prohibits FGM. They believed that FGM is mainly practiced for religious reasons and to reduce sexual desire/arousal. Health professionals are apparently not involved in performing FGM, and they don't support its continuation...
August 25, 2017: Health Care for Women International
https://www.readbyqxmd.com/read/28834789/sexual-functioning-in-patients-with-chronic-hepatitis-c-a-systematic-review
#14
Katerina Karaivazoglou, Evangelia-Eirini Tsermpini, Konstantinos Assimakopoulos, Christos Triantos
Chronic hepatitis C virus (HCV) infection is a systematic disease that affects several aspects of patients' well-being, including physical, mental, social, and sexual quality of life. In recent years, there has been a growing body of literature focusing on HCV patients' sexual health, providing evidence of clinically significant and enduring disturbances that disrupt everyday living, but commonly evade clinicians' attention. Relevant studies are characterized by considerable methodological heterogeneity and their findings should be interpreted using a systematic and integrative approach...
August 22, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28830817/evaluation-of-the-aphrodisiac-potential-of-a-chemically-characterized-aqueous-extract-of-tamarindus-indica-pulp
#15
Amita Rai, Snehashis Das, Mallikarjuna Rao Chamallamudi, Krishnadas Nandakumar, Raghavendra Shetty, Meghna Gill, Suhani Sumalatha, Raviraj Devkar, Karthik Gourishetti, Nitesh Kumar
ETHNOPHARMACOLOGICAL RELEVANCE: Tamarindus indica is an ingredient in the traditional aphrodisiac formulations in Africa and India. It is also a widely used food ingredient in other tropical countries. AIM OF THE STUDY: The present study was aimed to evaluate the aphrodisiac potential and reproductive safety profile of aqueous extract of Tamarindus indica in male Wistar rats. MATERIALS AND METHODS: The aqueous extract was prepared by maceration of pulp followed by reduction of volume in rotavapor under heat followed by freeze drying...
August 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28830740/how-do-psychological-risk-factors-predict-sexual-outcomes-a%C3%A2-comparison-of-four-models-of-young-women-s-sexual-outcomes
#16
Jessica S Tutino, Allison J Ouimet, Krystelle Shaughnessy
BACKGROUND: Recent research findings suggest that women who report high anxiety sensitivity (AS; the fear of physiologic sensations associated with anxiety) also report increased sexual dysfunction and decreased sexual satisfaction. Moreover, findings suggest that maladaptive emotion regulation (ER) can contribute to the relation between AS and psychological distress, thereby indirectly influencing sexual outcomes. Identifying relations among these variables and how they specifically relate to sexual outcomes could be vital for diagnostic and therapeutic purposes...
August 19, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28825956/management-of-sexual-problems-the-approach-of-mindfulness
#17
Sandra Vilarinho
PURPOSE OF REVIEW: During the last 10 years mindfulness has been progressively integrated into protocols for the management of sexual problems. The purpose of this study is to systematize potential benefits of mindfulness in sexual well-being (considering mind, emotion, and body), and to shortly review current applications and effectiveness of mindfulness-based interventions to the treatment of sexual problems. RECENT FINDINGS: The majority of evidence available focuses on women's sexual desire and arousal problems, although there are also preliminary findings for the effectiveness of mindfulness-based interventions in enhancing other components of the sexual response...
August 18, 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28820657/implications-of-no-recent-sexual-activity-casual-sex-or-exclusive-sex-for-college-women-s-sexual-well-being-depend-on-sexual-attitudes
#18
Christine E Kaestle, Larissa M Evans
OBJECTIVE: We examine how sexual activity relates to sexual well-being within the context of sexual attitudes, sexual agency, and sexual desire. PARTICIPANTS/METHODS: We surveyed 471 college women in 2012-14 who had ever had sex. RESULTS: Sexual agency and sexual desire consistently predicted well-being, regardless of recent sexual activity. There was a significant interaction between recent sexual activity (none, casual, or exclusive relationship) and sexual attitudes...
August 18, 2017: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/28817365/effect-of-flibanserin-treatment-on-body-weight-in-premenopausal-and-postmenopausal-women-with-hypoactive-sexual-desire-disorder-a-post-hoc-analysis
#19
Susan G Kornstein, James A Simon, Stuart C Apfel, James Yuan, Krista A Barbour, Robert Kissling
BACKGROUND: Flibanserin, a 5-HT1A agonist and 5-HT2A antagonist, is indicated for the treatment of acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. This post hoc analysis evaluated the effect of flibanserin treatment on body weight in premenopausal and postmenopausal women with HSDD. MATERIALS AND METHODS: This analysis included three 24-week, double-blind, placebo-controlled studies of flibanserin 100 mg each bedtime (qhs) in premenopausal women, a similarly designed study in postmenopausal women, and a 52-week, open-label extension study in premenopausal women...
August 17, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28814122/flibanserin-toxicity-in-a-toddler-following-ingestion
#20
Nicholas Granzella, Betty C Chen, Geoffrey S Baird, Matthew Valento
INTRODUCTION: Flibanserin is a medication recently approved by the FDA for treatment of generalized hypoactive sexual desire disorder (HSDD) in premenopausal women. Its mechanism of action is not fully understood but is thought to modulate serotonin receptors and increase levels of norepinephrine and dopamine. While much is known about toxicity of other drugs which affect these systems, there is little information about toxicity of flibanserin at this time. CASE: We present a case of a 2-year-old boy who ingested an estimated 600 mg of his mother's flibanserin...
August 17, 2017: Clinical Toxicology
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