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"Sexual desire"

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https://www.readbyqxmd.com/read/28328282/frequency-of-erectile-dysfunction-in-males-with-central-serous-chorioretinopathy
#1
Ayse Balkarli, Muhammet Kazim Erol, Soner Yalcinkaya, Rumeysa Selvinaz Erol
OBJECTIVES: To evaluate the frequency of sexual dysfunction and associated factors in patients with central serous chorioretinopathy (CSCR). MATERIAL AND METHODS: Fifty-eight CSCR patients who met the inclusion criteria and 99 age- and sex-matched healthy controls were prospectively investigated for sexual dysfunction and associated factors. All participants were investigated using the Beck Depression Inventory (BDI), Beck Anxiety Scale (BAS), and the15-question Index of Erectile Function-15 (IIEF-15) and by extensive examination of CSCR, associated factors, and confounding factors...
March 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/28325146/hypersexuality-as-a-neuropsychiatric-disorder-the-neurobiology-and-treatment-options
#2
Hatta Sidi, Muna Asiff, Jaya Kumar, Srijit Das, Nurul Hazwani Hatta, Cesar Alfonso
Hypersexuality refers to abnormally increased or extreme involvement in any sexual activity. It is clinically challenging, presents trans-diagnostically and there is extensive medical literature addressing nosology, pathogenesis and neuropsychiatric aspects. Classification includes deviant behaviours, diagnosable entities related to impulsivity, and obsessional phenomena. Some clinicians view an increase in sexual desire as 'normal' while psychodynamic theorists consider it ego-defensive at times alleviating unconscious anxiety rooted in intrapsychic conflicts...
March 21, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28323519/improvement-of-low-sexual-desire-due-to-antiandrogenic-combined-oral-contraceptives-after-switching-to-an-oral-contraceptive-containing-17%C3%AE-estradiol
#3
Salvatore Caruso, Stefano Cianci, Maria Cariola, Valentina Fava, Salvatore Di Pasqua, Antonio Cianci
OBJECTIVES: To investigate the effects of a combined oral contraceptive (COC) containing 17β-estradiol (E2) 1.5 mg and nomegestrol acetate 2.5 mg (NOMAC/E2) on the sexual health of women affected by low sexual desire due to COCs containing ethinylestradiol. MATERIALS AND METHODS: Eighty-three women (age range 19-32) participated in the study. Sex hormone-binding globulin (SHBG), total testosterone (TT), and free androgen index (FAI) were measured. The Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale (FSDS) questionnaires were used to assess sexual function and distress, respectively...
March 21, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28322856/orgasmic-function-after-radical-prostatectomy
#4
Kefu Du, Chong Zhang, Angela P Presson, Jonathan D Tward, William O Brant, Christopher B Dechet
PURPOSE: We examined post-prostatectomy orgasmic function (OF) and assessed for potential predictors. MATERIALS AND METHODS: Between 2005 and 2013, 499 men underwent radical prostatectomy and completed quality of life questionnaires prospectively preoperatively and at regular postoperative intervals. We used mixed effects logistic regression models to evaluate average differences in follow-up measures and interactions with time. RESULTS: At a median follow-up of 36 months, OF was worsened, stable, or improved in 300 (60...
March 18, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28319850/methylation-of-hpa-axis-related-genes-in-men-with-hypersexual-disorder
#5
Jussi Jokinen, Adrian E Boström, Andreas Chatzittofis, Diana M Ciuculete, Katarina Görts Öberg, John N Flanagan, Stefan Arver, Helgi B Schiöth
Hypersexual Disorder (HD) defined as non-paraphilic sexual desire disorder with components of compulsivity, impulsivity and behavioral addiction, and proposed as a diagnosis in the DSM 5, shares some overlapping features with substance use disorder including common neurotransmitter systems and dysregulated hypothalamic-pituitary-adrenal (HPA) axis function. In this study, comprising 67 HD male patients and 39 male healthy volunteers, we aimed to identify HPA-axis coupled CpG-sites, in which modifications of the epigenetic profile are associated with hypersexuality...
March 10, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28315587/the-effect-of-l-thyroxine-treatment-on-sexual-function-and-depressive-symptoms-in-men-with-autoimmune-hypothyroidism
#6
Robert Krysiak, Witold Szkróbka, Bogusław Okopień
BACKGROUND: Thyroid autoimmunity and mild hypothyroidism in women seem to be associated with sexual dysfunction and depressive symptoms. Data concerning similar associations in men are limited. The aim of this study was to investigate sexual functioning and depressive symptoms in men with autoimmune hypothyroidism. METHODS: The study population consisted of three groups: men with autoimmune overt hypothyroidism (group A), men with autoimmune subclinical hypothyroidism (group B) and healthy euthyroid males without thyroid autoimmunity (group C)...
January 17, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/28291031/a-sex-specific-dose-response-curve-for-testosterone-could-excessive-testosterone-limit-sexual-interaction-in-women
#7
Jill M Krapf, James A Simon
Testosterone treatment increases sexual desire and well-being in women with hypoactive sexual desire disorder; however, many studies have shown only modest benefits limited to moderate doses. Unlike men, available data indicate women show a bell-shaped dose-response curve for testosterone, wherein a threshold dosage of testosterone leads to desirable sexual function effects, but exceeding this threshold results in a lack of further positive sexual effects or may have a negative impact. Emotional and physical side-effects of excess testosterone, including aggression and virilization, may counteract the modest benefits on sexual interaction, providing a possible explanation for a threshold dose of testosterone in women...
March 13, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28287913/skills-vs-pills-comparative-effectiveness-for-low-sexual-desire
#8
Meenakshi Palaniappan, Rachel Heatherly, Laurie Mintz, Kathleen Connelly, Tessa Wimberley, Alexandra Balzer, Danielle Pierini, Katherine Vogel Anderson
This study compared the effectiveness of a skill-based bibliotherapy intervention and a placebo pill intervention purported to be efficacious in increasing women's sexual desire. Forty-five participants were randomized into the two groups after completing pre-test measures of sexual desire and functioning. After completing their interventions, participants completed 6-week post-test, and 12-week follow-up measures. Results demonstrated that when compared to the placebo pill group, the bibliotherapy group made statistically greater gains from pre-test to follow-up in sexual desire and satisfaction...
March 13, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28285412/symptoms-and-impacts-in-non-metastatic-castration-resistant-prostate-cancer-qualitative-study-findings
#9
Erin L Tomaszewski, Pierre Moise, Robert N Krupnick, Jared Downing, Margaret Meyer, Shevani Naidoo, Stefan Holmstrom
OBJECTIVES: We developed a conceptual model to define key concepts associated with patients' experiences with the signs, symptoms, and impacts of non-metastatic castration-resistant prostate cancer (M0-CRPC). METHODS: A targeted review of peer-reviewed literature, and other publicly available information, identified and categorized symptoms and impacts related to early-stage prostate cancer. Semi-structured interviews with five clinical experts helped determine the most relevant and important concepts for patients with M0-CRPC...
March 11, 2017: Patient
https://www.readbyqxmd.com/read/28278441/facilitation-of-sexual-behavior-in-ovariectomized-rats-by-estradiol-and-testosterone-a-preclinical-model-of-androgen-effects-on-female-sexual-desire
#10
Sherri Lee Jones, Nafissa Ismail, James G Pfaus
In the United States and Canada, there are no approved treatments for hypoactive sexual desire disorder in postmenopausal women. Testosterone improves female sexual desire in naturally- and surgically-menopausal women maintained on estrogen replacement therapy, and long-term safety data from randomized placebo-controlled clinical trials has yielded promising results. However, the mechanisms associated with its efficacy are not known, and could be addressed using preclinical rodent models; yet there is no systematic evaluation of the effects of estradiol and testosterone on female rat sexual behavior...
February 17, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28251311/sexual-activity-and-sexual-dysfunction-of-women-in-the-perinatal-period-a-longitudinal-study
#11
Stephanie Wallwiener, Mitho Müller, Anne Doster, Ruben Jeremias Kuon, Katharina Plewniok, Sandra Feller, Markus Wallwiener, Corinna Reck, Lina Maria Matthies, Christian Wallwiener
PURPOSE: Reduced sexual activity and dysfunctional problems are highly prevalent in the perinatal period, and there is a lack of data regarding the degree of normality during pregnancy. Several risk factors have been independently associated with a greater extent of Female Sexual Dysfunction (FSD). Therefore, this study aimed to assess the prevalence of sexual inactivity and sexual dysfunctions in German women during the perinatal period and the verification of potential risk factors...
March 1, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28240966/efficacy-of-internet-based-cognitive-behavioral-therapy-in-improving-sexual-functioning-of-breast-cancer-survivors-results-of-a-randomized-controlled-trial
#12
Susanna B Hummel, Jacques J D M van Lankveld, Hester S A Oldenburg, Daniela E E Hahn, Jacobien M Kieffer, Miranda A Gerritsma, Marianne A Kuenen, Nina Bijker, Paul J Borgstein, Gijsbert Heuff, Alexander M F Lopes Cardozo, Peter W Plaisier, Herman Rijna, Suzan van der Meij, Eric J van Dulken, Bart C Vrouenraets, Eva Broomans, Neil K Aaronson
Purpose We evaluated the effect of Internet-based cognitive behavioral therapy (CBT) on sexual functioning and relationship intimacy (primary outcomes) and body image, menopausal symptoms, marital functioning, psychological distress, and health-related quality of life (secondary outcomes) in breast cancer survivors (BCSs) with a DSM-IV diagnosis of a sexual dysfunction. Patients and Methods We randomly assigned 169 BCSs to either Internet-based CBT or a waiting-list control group. The CBT consisted of weekly therapist-guided sessions, with a maximum duration of 24 weeks...
February 27, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28237271/evidence-based-treatments-for-low-sexual-desire-in-women
#13
REVIEW
Lori A Brotto
Low sexual desire is the most common sexual complaint in women, with multinational studies finding that at least a third of women experience low sexual desire. No single etiology for the development of Female Sexual Interest/Arousal Disorder, the diagnosis laid out by the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders, has been established. There has been considerable interest in pharmacological approaches to improving low desire, and agents targeting a range of neurotransmitters have been examined...
February 22, 2017: Frontiers in Neuroendocrinology
https://www.readbyqxmd.com/read/28218586/systematic-review-of-occupational-therapy-and-adult-cancer-rehabilitation-part-2-impact-of-multidisciplinary-rehabilitation-and-psychosocial-sexuality-and-return-to-work-interventions
#14
Elizabeth G Hunter, Robert W Gibson, Marian Arbesman, Mariana D'Amico
This article is the second part of a systematic review of evidence for the effectiveness of cancer rehabilitation interventions within the scope of occupational therapy that address the activity and participation needs of adult cancer survivors. This article focuses on the use of multidisciplinary rehabilitation and interventions that address psychosocial outcomes, sexuality, and return to work. Strong evidence indicates that multidisciplinary rehabilitation benefits cancer survivors and that psychosocial strategies can reduce anxiety and depression...
March 2017: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/28203348/flibanserin-for-hypoactive-sexual-desire-disorder-place-in-therapy
#15
REVIEW
Faina Gelman, Jessica Atrio
The pathophysiology, diagnosis and treatment of female sexual interest in pre- and post-menopausal women present a complex arena for patients and physicians to navigate. Flibanserin was the first pharmacologic treatment, approved by the United States Food and Drug Administration in August 2015, for hypoactive sexual desire disorder (HSDD) in premenopausal women. Side effects, contraindications and lack of approval in postmenopausal women are all limitations, as are issues surrounding patient and physician knowledge and access...
January 2017: Therapeutic Advances in Chronic Disease
https://www.readbyqxmd.com/read/28202355/ovarian-hormone-fluctuations-predict-within-cycle-shifts-in-women-s-food-intake
#16
James R Roney, Zachary L Simmons
What role do ovarian hormones play in modulating day-to-day shifts in women's motivational priorities? In many nonhuman mammals, estradiol causes drops in feeding and foraging, progesterone reverses this effect, and the two hormones in combination produce cycle phase shifts characterized by lower food intake near ovulation when sexual receptivity is at its peak. Hormonal predictors of within-cycle shifts in women's total food intake have not been previously tested. Here, in a study with both daily hormone measures and self-reported food intake, we found that within-cycle fluctuations in estradiol negatively predicted shifts in food intake, progesterone fluctuations positively predicted them, and the two hormones together statistically mediated a significant peri-ovulatory drop in eating...
February 18, 2017: Hormones and Behavior
https://www.readbyqxmd.com/read/28193195/assessing-the-burden-of-treatment-emergent-adverse-events-associated-with-atypical-antipsychotic-medications
#17
Pierre-Michel Llorca, Christophe Lançon, Ann Hartry, T Michelle Brown, Dana B DiBenedetti, Siddhesh A Kamat, Clément François
BACKGROUND: Treatment of schizophrenia and major depressive disorder (MDD) with atypical antipsychotics (AAPs) show improved efficacy and reduced side effect burden compared with older antipsychotic medications. However, a risk of treatment-emergent adverse events (TEAEs) remains. TEAEs are hard to quantify and perspectives on the importance of TEAEs differ across patients and between patients and physicians. The current study is a qualitative assessment that investigates TEAEs of AAPs from both patient and physician perspectives to provide better understanding of the occurrence and burden of TEAEs associated with these medications...
February 13, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28178575/prevalence-of-female-sexual-dysfunction-in-brazil-a-systematic-review
#18
REVIEW
Raquel E Wolpe, Kamilla Zomkowski, Fabiana P Silva, Ana Paula A Queiroz, Fabiana F Sperandio
The aim of this systematic review is to investigate the prevalence of female sexual dysfunction in the Brazilian population. This is a systematic review conducted in July 2016 in which four databases were searched: MEDLINE/Pubmed, Scopus, LILACS, and Cinahl. Two investigators extracted the primary data, which were fully analyzed, and applied the inclusion/exclusion criteria. The search found 113 results, and 20 of them compounded the scope of this study. Only four of the studies showed good methodology quality...
January 18, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28164297/sexual-counselling-for-treating-or-preventing-sexual-dysfunction-in-women-living-with-female-genital-mutilation-a-systematic-review
#19
REVIEW
Uduak Okomo, Miriam Ogugbue, Elizabeth Inyang, Martin M Meremikwu
BACKGROUND: Female sexual dysfunction is the persistent or recurring decrease in sexual desire or arousal, the difficulty or inability to achieve an orgasm, and/or the feeling of pain during sexual intercourse. Impaired sexual function can occur with all types of female genital mutilation (FGM) owing to the structural changes, pain, or traumatic memories associated with the procedure. OBJECTIVES: To conduct a systematic review of randomized and nonrandomized studies into the effects of sexual counseling with or without genital lubricants on the sexual function of women living with FGM...
February 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28163083/sexual-function-and-quality-of-life-before-and-after-penile-prosthesis-implantation-following-radial-forearm-flap-phalloplasty
#20
Ezekiel E Young, Daniel Friedlander, Kathy Lue, Uzoma A Anele, Jacob L Khurgin, Trinity J Bivalacqua, Arthur L Burnett, Richard J Redett, John P Gearhart
OBJECTIVE: To provide sexual function and quality of life outcomes in patients with severe penile deficiency who underwent radial forearm flap phalloplasty with and without penile prosthesis implantation. PATIENTS AND METHODS: Patients with history of severe penile deficiency who underwent microsurgical radial forearm flap phalloplasty with and without penile prosthesis implantation between 2007 and 2014 were identified. They completed a set of web-based validated questionnaires including the International Index of Erectile Function, the Pediatric Penile Perception Score, the Sexual Quality of Life for Men, and several items addressing general quality of life...
February 2, 2017: Urology
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