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https://www.readbyqxmd.com/read/29319127/sexual-function-and-depressive-symptoms-in-young-men-with-hypothyroidism-receiving-levothyroxine-liothyronine-combination-therapy
#1
Robert Krysiak, Bogdan Marek, Bogusław Okopień
INTRODUCTION: Both overt and subclinical hypothyroidism are often accompanied by sexual dysfunction. Despite improving male sexual functioning, levothyroxine treatment does not always restore all its aspects. The aim of this study was to compare male sexual functioning and depressive symptoms between men with hypothyroidism receiving levothyroxine/liothyronine combination therapy and men receiving levothyroxine alone. MATERIAL AND METHODS: The study population consisted of 21 young levothyroxine-treated men with clinical symptoms of hypothyroidism in whom serum thyrotropin and thyroid hormone levels were within the normal limits...
January 10, 2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29310164/re-men-s-sexual-response-to-female-partner-s-intranasal-oxytocin-administration-for-hypoactive-sexual-desire-disorder-an-open-prospective-cohort-study
#2
https://www.readbyqxmd.com/read/29304401/experiences-of-sexual-harassment-are-associated-with-the-sexual-behavior-of-14-to-18-year-old-adolescents
#3
Riittakerttu Kaltiala-Heino, Hanna Savioja, Sari Fröjd, Mauri Marttunen
Subjection to sexual harassment is associated with a number of negative outcomes, such as internalizing and externalizing symptoms and a disinclination to attend school. Among adolescents, sexual harassment may increase with both their emerging sexual desires and increased socializing in mixed-gender peer groups during early adolescence. We set out to study the possible associations between normative and risk-taking sexual behavior and subjection to sexual harassment among adolescents between the ages of 14 and 18 years...
January 2, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29297781/internet-based-cognitive-behavioral-therapy-realizes-long-term-improvement-in-the-sexual-functioning-and-body-image-of-breast-cancer-survivors
#4
Susanna B Hummel, Jacques Jdm van Lankveld, Hester Sa Oldenburg, Daniela Ee Hahn, Jacobien M Kieffer, Miranda A Gerritsma, Marianne A Kuenen, Nina Bijker, Paul J Borgstein, Gijsbert Heuff, Alexander Mf Lopes Cardozo, Peter W Plaisier, Herman Rijna, Suzan van der Meij, Eric J van Dulken, Bart C Vrouenraets, Eva Broomans, Neil K Aaronson
The study aim was to evaluate the long-term efficacy of internet-based cognitive behavioral therapy (CBT) for sexual dysfunctions in 84 breast cancer survivors (BCS). The positive effects of the intervention on overall sexual functioning, sexual desire, sexual arousal, vaginal lubrication, discomfort during sex, sexual distress and body image observed immediate post-treatment were maintained at 3- and 9-months follow-up. Although sexual pleasure decreased during follow-up, it did not return to baseline levels...
January 3, 2018: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/29294968/situational-and-dispositional-determinants-of-college-men-s-perception-of-women-s-sexual-desire-and-consent-to-sex-a-factorial-vignette-analysis
#5
Ashton M Lofgreen, Richard E Mattson, Samantha A Wagner, Edwin G Ortiz, Matthew D Johnson
Sexual victimization of women by men on college campuses is a growing societal concern, with research identifying a host of situational and characterological factors that may predict men's likelihood to engage in sexual misconduct. In the present study, we examined the relative contribution and potential interplay of these various determinants on college men's perceptions of women's sexual desire and consent in hypothetical dating scenarios depicting a sexual interaction. We found that the men ( N = 145) in this sample (a) conflated sexual desire with consent, (b) varied their appraisals of consent and desire depending on whether and how the woman in the vignette communicated consent or refusal, (c) perceived higher levels of consent if the man in the vignette had intercourse with the woman previously and as a function of escalating sexual intimacy in the ongoing interaction, (d) endorsed higher levels of perceived desire and consent across situations if they more strongly held rape-supportive attitudes, and (e) moderated their association between situational factors and perceptions of a woman's sexual intentions based on their endorsement of rape myths and a hypermasculine ideology...
November 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29289554/efficacy-and-safety-of-on-demand-use-of-2-treatments-designed-for-different-etiologies-of-female-sexual-interest-arousal-disorder-3-randomized-clinical-trials
#6
Adriaan Tuiten, Kim van Rooij, Jos Bloemers, Christoph Eisenegger, Jack van Honk, Rob Kessels, Sheryl Kingsberg, Leonard R Derogatis, Leo de Leede, Jeroen Gerritsen, Hans P F Koppeschaar, Berend Olivier, Walter Everaerd, Henderik W Frijlink, Daniël Höhle, Robert P J de Lange, Koen B E Böcker, James G Pfaus
BACKGROUND: In women, low sexual desire and/or sexual arousal can lead to sexual dissatisfaction and emotional distress, collectively defined as female sexual interest/arousal disorder (FSIAD). Few pharmaceutical treatment options are currently available. AIM: To investigate the efficacy and safety of 2 novel on-demand pharmacologic treatments that have been designed to treat 2 FSIAD subgroups (women with low sensitivity for sexual cues and women with dysfunctional over-activation of sexual inhibition) using a personalized medicine approach using an allocation formula based on genetic, hormonal, and psychological variables developed to predict drug efficacy in the subgroups...
December 27, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29289374/safety-of-flibanserin-in-women-treated-with-antidepressants-a-randomized-placebo-controlled-study
#7
Anita H Clayton, Harry A Croft, James Yuan, Louise Brown, Robert Kissling
BACKGROUND: Depression is often associated with sexual dysfunction, and pharmacologic treatment for hypoactive sexual desire disorder can be considered in women receiving treatment for depression. AIM: To evaluate the safety of flibanserin in women treated for depression with selective serotonin reuptake inhibitors or serotonin and norepinephrine reuptake inhibitors. METHODS: In this double-blinded, randomized, placebo-controlled trial, women with remitted or mild depression treated with selective serotonin reuptake inhibitors or serotonin and norepinephrine reuptake inhibitors who were not postmenopausal and were experiencing symptoms of hypoactive sexual desire disorder (ie, decreased sexual desire and related distress) received flibanserin 50 mg at bedtime (qhs) for 2 weeks and up-titrated to 100 mg qhs, flibanserin 100 mg qhs for the entire treatment period, or placebo for up to 12 weeks...
January 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29288108/sexual-dysfunction-after-good-grade-aneurysmal-subarachnoid-hemorrhage
#8
Lorenz Epprecht, Michael Messerli, Robin Samuel, Martin Seule, Johannes Weber, Jean-Yves Fournier, Werner Surbeck
OBJECTIVE: Our aim was to assess the consequences of aneurysmal subarachnoid hemorrhage (aSAH) on sexual pleasure in patients with an otherwise favorable neurological outcome. METHODS: Anonymous, standardized questionnaires concerning sexual function, including the International Index of Erectile Function, Female Sexual Function Index, and a statement on subjective change in sexual pleasure after aSAH, were completed by 33 patients treated at the Cantonal Hospital St...
December 26, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29287282/general-sexual-desire-but-not-desire-for-uncommitted-sexual-relationships-tracks-changes-in-women-s-hormonal-status
#9
Benedict C Jones, Amanda C Hahn, Claire I Fisher, Hongyi Wang, Michal Kandrik, Lisa M DeBruine
Several recent longitudinal studies have investigated the hormonal correlates of both young adult women's general sexual desire and, more specifically, their desire for uncommitted sexual relationships. Findings across these studies have been mixed, potentially because each study tested only small samples of women (Ns = 43, 33, and 14). Here we report results from a much larger (N = 375) longitudinal study of hormonal correlates of young adult women's general sexual desire and their desire for uncommitted sexual relationships...
December 21, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29282516/the-morbidity-of-sexual-dysfunction-of-125-chinese-women-following-different-types-of-radical-hysterectomy-for-gynaecological-malignancies
#10
Xueqin Wang, Chunlin Chen, Ping Liu, Weili Li, Liling Wang, Yunlu Liu
PURPOSE: Due to early detection and effective treatment, quality of sexual life of patients with gynaecological malignancies has become an important issue. However, the morbidity of sexual dysfunction and the proportion of different kinds of sexual dysfunction after radical hysterectomy are unclear. The aim of the current study was to assess the morbidity of sexual dysfunction and to conduct multivariate logistic regression analysis of patients' sexual dysfunction. METHODS: Between July 2007 and December 2012, 125 women underwent radical hysterectomy, modified radical hysterectomy, and nerve-sparing radical hysterectomy were administered a self-reported sexual function questionnaire...
December 27, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29281564/anxiety-dispositional-mindfulness-and-sexual-desire-in-men-consulting-in-clinical-sexology-a-mediational-model
#11
Julie Déziel, Natacha Godbout, Martine Hébert
This study aimed to examine dispositional mindfulness as a mediator of the relationship between anxiety and sexual desire in men consulting in clinical sexology. A sample of 105 adult men seeking sex therapy completed measures of dispositional mindfulness, anxiety, and sexual desire. Close to a third (28.7%) of participants reported low sexual desire as their main reason to consult in sex therapy. Path analysis confirmed a mediation model and revealed that the association between anxiety and lower sexual desire was fully mediated by dispositional mindfulness...
December 27, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/29278235/role-of-hormones-in-hypoactive-sexual-desire-disorder-and-current-treatment
#12
Ahmed AlAwlaqi, Houda Amor, Mohamed E Hammadeh
Over the decades, female sexual dysfunction (FSD) has grown to be an increasingly potential problem that complicates the quality of life among women. In the current review, FSD refers to recurrent and persistent problems with sexual orgasm, desire, or response. One of the most common subtypes of FSD that has evoked increased research interest in the scientific community is hyposexuality. Today, there is a consensus that hyposexuality is a multifactorial condition that manifests with reduced sexual desire resulting in significant interpersonal distress...
December 15, 2017: Journal of the Turkish German Gynecological Association
https://www.readbyqxmd.com/read/29244527/motivations-for-extradyadic-infidelity-revisited
#13
Dylan Selterman, Justin R Garcia, Irene Tsapelas
Relationship infidelities are motivated by many distinct factors, with previous research indicating motivations of dissatisfaction, neglect, anger, and sexual desire (Barta & Kiene, 2005). We expand on this by demonstrating additional, empirically distinct motivations for infidelity. Using an Internet-based questionnaire, participants (N = 495), most of whom were young adults, self-reported their infidelities. In addition to evidence for previously studied motivations, our data demonstrate additional factors, including lack of love ("I had 'fallen out of love with' my primary partner"), low commitment ("I was not very committed to my primary partner"), esteem ("I wanted to enhance my popularity"), gaining sexual variety ("I wanted a greater variety of sexual partners"), and situational factors ("I was drunk and not thinking clearly")...
December 15, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/29242708/physical-attractiveness-and-women-s-hiv-risk-in-rural-malawi
#14
Margaret Frye, Sophia Chae
BACKGROUND: Qualitative evidence from sub-Saharan Africa, where a generalized AIDS epidemic exists, suggests that attractiveness may play a role in shaping individual-level HIV risk. Attractive women, who are often blamed for the epidemic and stigmatized, are believed to pose a higher HIV risk because they are viewed as having more and riskier partners. OBJECTIVE: We examine the association between perceived attractiveness and HIV infection and risk in rural Malawi in the midst of the country's severe AIDS epidemic...
2017: Demographic Research
https://www.readbyqxmd.com/read/29225554/recent-developments-in-psychopharmaceutical-approaches-to-treating-female-sexual-interest-and-arousal-disorder
#15
REVIEW
Stephanie Both
Purpose of Review: This review summarizes the recent literature and empirical studies on psychopharmacological approaches to treating female sexual interest/arousal disorder (FSIAD). Recent Findings: Several new drugs for FSIAD that are intended to increase sexual responsiveness by influencing central excitatory and inhibitory neuromodulatory processes are under development. Studies on flibanserin resulted in the first approved medication for the treatment of low sexual desire in premenopausal women...
2017: Current Sexual Health Reports
https://www.readbyqxmd.com/read/29198512/understanding-the-role-of-serotonin-in-female-hypoactive-sexual-desire-disorder-and-treatment-options
#16
REVIEW
Harry A Croft
BACKGROUND: The neurobiology of sexual response is driven in part by dopamine and serotonin-the former modulating excitatory pathways and the latter regulating inhibitory pathways. Neurobiological underpinnings of hypoactive sexual desire disorder (HSDD) are seemingly related to overactive serotonin activity that results in underactive dopamine activity. As such, pharmacologic agents that decrease serotonin, increase dopamine, or some combination thereof, have therapeutic potential for HSDD...
December 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29198510/does-calculated-free-testosterone-overcome-total-testosterone-in-protecting-from-sexual-symptom-impairment-findings-of-a-cross-sectional-study
#17
Luca Boeri, Paolo Capogrosso, Eugenio Ventimiglia, Walter Cazzaniga, Filippo Pederzoli, Donatella Moretti, Federico Dehò, Emanuele Montanari, Francesco Montorsi, Andrea Salonia
BACKGROUND: Although erectile dysfunction (ED) has been associated with low circulating total testosterone (TT) levels, the utility of free testosterone (FT) over TT is debatable. AIM: To assess the relative impact of low TT and low calculated FT (cFT) on androgen-related sexual symptoms in men with ED. METHODS: Data from 485 men were analyzed. Comorbidities were scored with the Charlson Comorbidity Index (CCI). Patients completed the International Index of Erectile Function (IIEF) and the Beck Inventory for Depression (BDI)...
December 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29198504/female-sexual-dysfunction-medical-and-psychological-treatments-committee-14
#18
Sheryl A Kingsberg, Stanley Althof, James A Simon, Andrea Bradford, Johannes Bitzer, Joana Carvalho, Kathryn E Flynn, Rossella E Nappi, Jennifer B Reese, Roya L Rezaee, Leslie Schover, Jan L Shifrin
INTRODUCTION: Since the millennium we have witnessed significant strides in the science and treatment of female sexual dysfunction (FSD). This forward progress has included (i) the development of new theoretical models to describe healthy and dysfunctional sexual responses in women; (ii) alternative classification strategies of female sexual disorders; (iii) major advances in brain, hormonal, psychological, and interpersonal research focusing on etiologic factors and treatment approaches; (iv) strong and effective public advocacy for FSD; and (v) greater educational awareness of the impact of FSD on the woman and her partner...
December 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29198449/effects-of-flibanserin-on-the-pharmacokinetics-of-a-combined-ethinylestradiol-levonorgestrel-oral-contraceptive-in-healthy-premenopausal-women-a-randomized-crossover-study
#19
Crista Johnson-Agbakwu, Louise Brown, James Yuan, Robert Kissling, David J Greenblatt
PURPOSE: This study aimed to investigate the effect of steady-state exposure to flibanserin, a 5-HT1A agonist/5-HT2A antagonist approved for the treatment of hypoactive sexual desire disorder in premenopausal women, on the single-dose pharmacokinetics of the contraceptive steroids ethinylestradiol and levonorgestrel in healthy premenopausal women. METHODS: Healthy female volunteers (N = 24) received 2 single doses of a combined oral contraceptive containing ethinylestradiol 30 μg and levonorgestrel 150 μg, either alone (reference) or preceded by treatment with flibanserin 100 mg once daily for 14 days (test)...
November 30, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29182498/effect-of-single-session-cryogen-cooled-monopolar-radiofrequency-therapy-on-sexual-function-in-women-with-vaginal-laxity-the-viveve-i-trial
#20
Michael Krychman, Christopher G Rowan, Bruce B Allan, Scott Durbin, Ashley Yacoubian, Deborah Wilkerson
OBJECTIVE: This subanalysis of the VIVEVE I trial aimed to evaluate the impact of cryogen-cooled monopolar radiofrequency (CMRF) therapy, for the treatment of vaginal laxity, on the domains of sexual function included in the Female Sexual Function Index (FSFI). MATERIALS AND METHODS: The VIVEVE I clinical trial was prospective, randomized, single-blind, and Sham-controlled. Nine clinical study centers in Canada, Italy, Spain, and Japan were included. This subanalysis included premenopausal women with self-reported vaginal laxity who had ≥1 term vaginal delivery and a baseline FSFI total score ≤26...
November 28, 2017: Journal of Women's Health
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