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Influenza vaccine 2016-2017

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https://www.readbyqxmd.com/read/29432091/influenza-a-h7n9-virus-antibody-responses-in-survivors-1-year-after-infection-china-2017
#1
Mai-Juan Ma, Cheng Liu, Meng-Na Wu, Teng Zhao, Guo-Lin Wang, Yang Yang, Hong-Jing Gu, Peng-Wei Cui, Yuan-Yuan Pang, Ya-Yun Tan, Hui Hang, Bao Lin, Jiang-Chun Qin, Li-Qun Fang, Wu-Chun Cao, Li-Ling Cheng
Avian influenza A(H7N9) virus has caused 5 epidemic waves in China since its emergence in 2013. We investigated the dynamic changes of antibody response to this virus over 1 year postinfection in 25 patients in Suzhou City, Jiangsu Province, China, who had laboratory-confirmed infections during the fifth epidemic wave, Oct 1, 2016-February 14, 2017. Most survivors had relatively robust antibody responses that decreased but remained detectable at 1 year. Antibody response was variable; several survivors had low or undetectable antibody titers...
April 17, 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29408438/vaccination-of-healthcare-workers-against-influenza-does-a-day-off-make-a-difference
#2
Helena C Maltezou, Olympia Christophilea, Anastasia Tedoma, Panos Katerelos, George Dounias
We present the results of the actions undertaken in order to increase influenza vaccine uptake by healthcare workers (HCWs) in Greece during the 2016-2017 influenza season. Influenza vaccination among HCWs increased from 10.9% in acute care hospitals and 24.3% in primary healthcare centers during 2015-2016 to 18% in acute care hospitals and 34.6% in primary healthcare centers during 2016-2017. We found that vaccination within the healthcare facility and use of reward systems were statistically significantly associated with increased vaccination rates...
February 2, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29388197/vaccines-for-preventing-influenza-in-the-elderly
#3
REVIEW
Vittorio Demicheli, Tom Jefferson, Carlo Di Pietrantonj, Eliana Ferroni, Sarah Thorning, Roger E Thomas, Alessandro Rivetti
BACKGROUND: The consequences of influenza in the elderly (those age 65 years or older) are complications, hospitalisations, and death. The primary goal of influenza vaccination in the elderly is to reduce the risk of death among people who are most vulnerable. This is an update of a review published in 2010. Future updates of this review will be made only when new trials or vaccines become available. Observational data included in previous versions of the review have been retained for historical reasons but have not been updated because of their lack of influence on the review conclusions...
February 1, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29388196/vaccines-for-preventing-influenza-in-healthy-adults
#4
REVIEW
Vittorio Demicheli, Tom Jefferson, Eliana Ferroni, Alessandro Rivetti, Carlo Di Pietrantonj
BACKGROUND: The consequences of influenza in adults are mainly time off work. Vaccination of pregnant women is recommended internationally. This is an update of a review published in 2014. Future updates of this review will be made only when new trials or vaccines become available. Observational data included in previous versions of the review have been retained for historical reasons but have not been updated due to their lack of influence on the review conclusions. OBJECTIVES: To assess the effects (efficacy, effectiveness, and harm) of vaccines against influenza in healthy adults, including pregnant women...
February 1, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29388195/vaccines-for-preventing-influenza-in-healthy-children
#5
REVIEW
Tom Jefferson, Alessandro Rivetti, Carlo Di Pietrantonj, Vittorio Demicheli
BACKGROUND: The consequences of influenza in children and adults are mainly absenteeism from school and work. However, the risk of complications is greatest in children and people over 65 years of age. This is an update of a review published in 2011. Future updates of this review will be made only when new trials or vaccines become available. Observational data included in previous versions of the review have been retained for historical reasons but have not been updated because of their lack of influence on the review conclusions...
February 1, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29381077/brief-report-department-of-defense-global-laboratory-based-influenza-surveillance-program-s-influenza-vaccine-effectiveness-estimates-and-surveillance-trends-for-2016-2017-influenza-season
#6
https://www.readbyqxmd.com/read/29362167/the-cost-of-interventions-to-increase-influenza-vaccination-a-systematic-review
#7
REVIEW
Laura J Anderson, Paul Shekelle, Emmett Keeler, Lori Uscher-Pines, Roberta Shanman, Sally Morton, Gursel Aliyev, Teryl K Nuckols
CONTEXT: Influenza vaccination rates remain below Healthy People 2020 goals. This project sought to systematically review economic evaluations of healthcare-based quality improvement interventions for improving influenza vaccination uptake among general populations and healthcare workers. EVIDENCE ACQUISITION: The databases MEDLINE, Econlit, Centre for Reviews & Dissemination, Greylit, and Worldcat were searched in July 2016 for papers published from January 2004 to July 2016...
February 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29346614/influenza-vaccine-effectiveness-against-influenza-a-h3n2-hospitalizations-in-children-in-hong-kong-in-a-prolonged-season-2016-17
#8
Susan S Chiu, Mike Y W Kwan, Shuo Feng, Joshua S C Wong, Chi-Wai Leung, Eunice L Y Chan, Kwok-Hung Chan, Tak-Keung Ng, Wing-Kin To, Benjamin J Cowling, J S Malik Peiris
Background: Influenza A(H3N2) viruses circulated for 12 consecutive months in Hong Kong in 2016-2017, peaking in late June and July 2017. The objective of our study was to estimate the effectiveness of influenza vaccination in preventing hospitalizations in children in Hong Kong. Methods: We conducted a test-negative study between September 1 2016 and August 31 2017, enrolling children 6 months to 17 years of age hospitalized for an acute respiratory infection. Influenza was diagnosed by PCR on nasopharyngeal aspirates...
January 16, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29303959/influenza-vaccination-rates-among-parents-and-health-care-personnel-in-a-german-neonatology-department
#9
Horst Buxmann, Anne Daun, Sabine Wicker, Rolf Lambert Schlößer
The influenza vaccination is recommended for all German pregnant women and health care personnel (HCP). We are the first to publish vaccination rates of mothers of hospitalized newborns and HCP in neonatal units. Between September 2016 and March 2017, data were collected in our level-III neonatology department in this descriptive multidisciplinary study, using an anonymous questionnaire. As a result, 513 persons were asked to participate, including 330 parents and 183 HCP. We received an 80.3% (412/513) response rate, 87...
January 5, 2018: Vaccines
https://www.readbyqxmd.com/read/29300686/220-mutation-in-the-hemagglutinin-of-avian-influenza-a-h7n9-virus-alters-antigenicity-during-vaccine-strain-development
#10
Liqi Liu, Jian Lu, Zi Li, Jianfang Zhou, Junfeng Guo, Xiyan Li, Jia Liu, Yuelong Shu, Dayan Wang
Since the first confirmed case of H7N9 infection was reported in China, there have been five epidemic waves of human H7N9 infections between 2013 and 2017. The fifth wave differed from the previous four waves in that highly pathogenic avian influenza (HPAI) H7N9 viruses with multiple basic amino acids at the cleavage site were detected in humans, poultry and environmental samples. The HPAI H7N9 viruses were genetically and antigenically distinct from previous H7N9 viruses. Therefore, a new candidate vaccine virus(CVV) derived from a HPAI A/Guangdong/17SF003/2016-like virus was proposed by the World Health Organization(WHO)...
January 4, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29299891/the-korean-influenza-national-immunization-program-history-and-present-status
#11
REVIEW
Jae Won Yun, Ji Yun Noh, Joon Young Song, Chaemin Chun, Yunju Kim, Hee Jin Cheong
The Korean influenza national immunization program was first established as an interim program in 1997, administering the influenza vaccine to low-income elderly adults. In 2005, the program assumed its present form of providing free influenza vaccination to adults aged ≥65 years. After turning over the influenza vaccination for elderly adults to the private sectors in 2015, the influenza vaccination coverage rate among this population increased to >80%. In addition, after the 2009 H1N1 influenza epidemic crisis, the vaccine was domestically produced...
December 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/29297852/predominance-of-influenza-a-h3n2-viruses-during-the-2016-2017-season-in-bulgaria
#12
Neli Korsun, Svetla Angelova, Ivelina Trifonova, Iren Tzotcheva, Sirma Mileva, Silvia Voleva, Irina Georgieva, Penka Perenovska
PURPOSE: Influenza viruses are characterised by high variability, which makes them able to cause annual epidemics. The aim of this study is to determine the antigenic and genetic characteristics of influenza viruses circulating in Bulgaria during the 2016/2017 season. METHODOLOGY: The detection and typing/subtyping of influenza viruses were performed using real time RT-PCR. Results of antigenic characterisation, phylogenetic and amino acid sequence analyses of representative influenza strains are presented herein...
January 3, 2018: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29278832/an-epidemic-surge-of-influenza-a-h3n2-virus-at-the-end-of-the-2016-2017-season-in-taiwan-with-an-increased-viral-genetic-heterogeneity
#13
Ji-Rong Yang, Shu-Zhen Hsu, Chuan-Yi Kuo, Hsiang-Yi Huang, Teng-Yung Huang, Hsiao-Chi Wang, Ming-Tsan Liu
BACKGROUND: The epidemic of the 2016-2017 influenza season in Taiwan started early with moderate activity and was predominated by the influenza A(H3N2) virus. However, the influenza activity increased dramatically during the late stage of the 2016-2017 season. OBJECTIVES: The genetic and antigenic characteristics of the influenza A(H3N2) virus circulating in Taiwan during the 2016-2017 season were investigated. The relationship between virus clades and the patients' 2016-2017 vaccination histories was determined...
December 22, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29274700/erratum-to-predominance-of-influenza-a-h3n2-virus-genetic-subclade-3c-2a1-during-an-early-2016-17-influenza-season-in-europe-contribution-of-surveillance-data-from-world-health-organization-who-european-region-to-the-who-vaccine-composition-consultation-for
#14
https://www.readbyqxmd.com/read/29246674/immunization-practices-of-u-s-obstetrician-gynecologists-for-pregnant-patients
#15
Sean T O'Leary, Laura E Riley, Megan C Lindley, Mandy A Allison, Lori A Crane, Laura P Hurley, Brenda L Beaty, Michaela Brtnikova, Margaret Collins, Alison P Albert, Allison K Fisher, Angela J Jiles, Allison Kempe
INTRODUCTION: U.S. obstetrician/gynecologists play a critical role as vaccinators of pregnant women. However, little is known about their current immunization practices. Thus, study objectives were to determine (1) practices related to assessment of vaccination status and vaccine delivery for pregnant patients; (2) barriers to stocking and administering vaccines; and (3) factors associated with administering both influenza and tetanus, diphtheria, and acellular pertussis (Tdap) vaccines...
December 12, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29189713/low-prevalence-of-enzootic-equine-influenza-virus-among-horses-in-mongolia
#16
Alexandra Sack, Ulziimaa Daramragchaa, Maitsetseg Chuluunbaatar, Battsetseg Gonchigoo, Boldbaatar Bazartseren, Nyamdorj Tsogbadrakh, Gregory C Gray
Horses are critically important for Mongolian herders' livelihoods, providing transportation and food products, and playing important cultural roles. Equine influenza virus (EIV) epizootics have been frequent among Mongolia's horses, with five occurring since 1970. We sought to estimate the prevalence for EIV infection among horses and Bactrian camels with influenza-like illness between national epizootics. In 2016-2017, active surveillance for EIV was periodically performed in four aimags (provinces). Nasal swabs were collected from 680 horses and 131 camels...
November 30, 2017: Pathogens
https://www.readbyqxmd.com/read/29167344/comparison-of-the-efficacy-of-n9-neuraminidase-specific-monoclonal-antibodies-against-influenza-a-h7n9-virus-infection
#17
Hongquan Wan, Li Qi, Jin Gao, Laura K Couzens, Lianlian Jiang, Yamei Gao, Zong-Mei Sheng, Sharon Fong, Megan Hahn, Surender Khurana, Jeffery K Taubenberger, Maryna C Eichelberger
The fifth wave of A(H7N9) virus infection in China from 2016 to 2017 caused great concern due to the large number of individuals infected, the isolation of drug-resistant viruses and emergence of highly pathogenic strains. Antibodies against neuraminidase (NA) provide added benefit to hemagglutinin-specific immunity and may be an important contributor to the effectiveness of A(H7N9) vaccines. We generated a panel of mouse monoclonal antibodies (MAbs) to identify antigenic domains on NA of the novel A(H7N9) virus and compared their functional properties...
November 22, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29145568/seasonal-influenza-vaccine-effectiveness-in-preventing-laboratory-confirmed-influenza-in-primary-care-in-israel-2016-2017-season-insights-into-novel-age-specific-analysis
#18
Yaniv Stein, Michal Mandelboim, Hanna Sefty, Rakefet Pando, Ella Mendelson, Tamy Shohat, Aharona Glatman-Freedman
Background: The 2016-2017 influenza season in Israel was dominated by the circulation of influenza A(H3N2). Influenza vaccine is recommended for the entire population in Israel over the age of six months. The inactivated influenza vaccine was chosen for use this season. Methods: We estimated the 2016-2017 end-of-season influenza vaccine effectiveness (VE) in preventing influenza-like illness (ILI) due to influenza A(H3N2), using the test-negative design. Age-specific VE was estimated using a moving age window and weekly analysis...
November 14, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29128383/influenza-vaccination-in-preventing-outbreaks-in-schools-a-long-term-ecological-overview
#19
Yang Pan, Quanyi Wang, Peng Yang, Li Zhang, Shuangsheng Wu, Yi Zhang, Ying Sun, Wei Duan, Chunna Ma, Man Zhang, Xingxing Zhang, C Raina MacIntyre
Influenza vaccination is the most effective way to reduce the incidence of influenza infections. However, the role of influenza vaccination, such as school-based influenza vaccination, in preventing the influenza outbreaks in schools remains unclear now. In this study, a total of 286 school febrile outbreaks involving 6863 cases in the Beijing area from September 1, 2006 to March 31, 2017 were analyzed. We also tested 294 circulating strains isolated in Beijing during the same period and compared with that of vaccine strains identified every influenza season...
November 8, 2017: Vaccine
https://www.readbyqxmd.com/read/29114729/cost-effectiveness-of-strategies-for-offering-influenza-vaccine-in-the-pediatric-emergency-department
#20
Rebecca J Hart, Michelle D Stevenson, Michael J Smith, A Scott LaJoie, Keith Cross
Importance: Influenza is a significant public health burden, causing morbidity and mortality in children, yet vaccination rates remain low. Vaccination in the pediatric emergency department (PED) setting may be beneficial but, to date, has not been proven to be cost-effective. Objective: To compare the cost-effectiveness of 4 strategies for PED-based influenza vaccine: offering vaccine to all patients, only to patients younger than 5 years, only to high-risk patients (all ages), or to no patients...
November 6, 2017: JAMA Pediatrics
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