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Influenza vaccine 2016-2017

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https://www.readbyqxmd.com/read/29020179/the-household-influenza-vaccine-effectiveness-study-lack-of-antibody-response-and-protection-following-receipt-of-2014-2015-influenza-vaccine
#1
Joshua G Petrie, Ryan E Malosh, Caroline K Cheng, Suzanne E Ohmit, Emily T Martin, Emileigh Johnson, Rachel Truscon, Maryna C Eichelberger, Larisa V Gubareva, Alicia M Fry, Arnold S Monto
Background: Antigenically drifted A(H3N2) viruses circulated extensively during the 2014-2015 influenza season. Vaccine effectiveness (VE) was low and not significant among outpatients but in a hospitalized population was 43%. At least one study paradoxically observed increased A(H3N2) infection among those vaccinated 3 consecutive years. Methods: We followed a cohort of 1341 individuals from 340 households. VE against laboratory-confirmed influenza was estimated...
July 20, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28986441/changes-in-influenza-vaccination-rates-after-withdrawal-of-live-vaccine
#2
Steve G Robison, Aaron G Dunn, Deborah L Richards, Richard F Leman
BACKGROUND: Before the start of the 2016-2017 influenza season, the Advisory Committee on Immunization Practices withdrew its recommendation promoting the use of live attenuated influenza vaccines (LAIVs). There was concern that this might lessen the likelihood that those with a previous LAIV would return for an injectable influenza vaccine (IIV) and that child influenza immunization rates would decrease overall. METHODS: Using Oregon's statewide immunization registry, the ALERT Immunization Information System, child influenza immunization rates were compared across the 2012-2013 through 2016-2017 seasons...
October 6, 2017: Pediatrics
https://www.readbyqxmd.com/read/28957044/influenza-vaccination-coverage-among-pregnant-women-united-states-2016-17-influenza-season
#3
Helen Ding, Carla L Black, Sarah Ball, Rebecca V Fink, Walter W Williams, Amy Parker Fiebelkorn, Peng-Jun Lu, Katherine E Kahn, Denise V D'Angelo, Rebecca Devlin, Stacie M Greby
Pregnant women and their infants are at increased risk for severe influenza-associated illness (1), and since 2004, the Advisory Committee on Immunization Practices (ACIP) has recommended influenza vaccination for all women who are or might be pregnant during the influenza season, regardless of the trimester of the pregnancy (2). To assess influenza vaccination coverage among pregnant women during the 2016-17 influenza season, CDC analyzed data from an Internet panel survey conducted during March 28-April 7, 2017...
September 29, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28956803/infant-immunization-coverage-in-italy-2000-2016
#4
Carlo Signorelli, Anna Odone, Paola Cella, Stefania Iannazzo, Fortunato D'Ancona, Raniero Guerra
BACKGROUND: In Italy, national-level immunization polices are included in the National Immunization Prevention Plan (PNPV), whose latest edition - 2017-2019 PNPV - was finally approved in February 2017. Coverage rates are a key measure of immunization system performance; it can inform and support national and regional polices' implementation monitoring, as well as measure the impact of interventions aimed at increasing vaccine uptake. METHODS: We collected, analysed and critically interpreted 2000-2016 Italian national infant immunization coverage trends, by different vaccine, target population, and by Region...
July 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28945700/perspectives-from-the-society-for-pediatric-research-spr-decreased-effectiveness-of-the-live-attenuated-influenza-vaccine-laiv
#5
REVIEW
Michelle A Gill, Elizabeth P Schlaudecker
Purpose of SPR Perspectives Reviews: Address contemporary scientific issues and controversies by leveraging the expertise of SPR membersIncrease SPR member engagement with the journalPair established and younger SPR members to simultaneously increase interaction between SPR members and create opportunities for mentorship The intranasal Live Attenuated Influenza Vaccine (LAIV), FluMist, has been widely appreciated by pediatricians, parents and children alike for its ease of administration. Concerns regarding lack of effectiveness in recent influenza seasons, however, led to the CDC Advisory Committee on Immunization Practices (ACIP) recommendation to administer inactivated influenza vaccines (IIV), and not LAIV, during the 2016-17 and 2017-18 seasons...
September 25, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28895750/brief-report-mid-season-influenza-vaccine-effectiveness-estimates-for-the-2016-2017-influenza-season
#6
Elizabeth Toure, Angelia A Eick-Cost, Anthony W Hawksworth, Michael J Cooper, Zheng Hu, Christopher A Myers, Peter E Kammerer, Michelle N Ricketts, Susan Federinko
No abstract text is available yet for this article.
August 2017: MSMR
https://www.readbyqxmd.com/read/28890192/workplace-availability-risk-group-and-perceived-barriers-predictive-of-2016-17-influenza-vaccine-uptake-in-the-united-states-a-cross-sectional-study
#7
Paula M Luz, Riley E Johnson, Heidi E Brown
BACKGROUND: Seasonal influenza, though mostly self-limited in the healthy adult, may lead to severe disease and/or complications in subpopulations. Annual influenza vaccination is available in many countries with coverage goals rarely being met. We conducted a cross-sectional study of influenza vaccine uptake and explored socio-demographic, economic, and psychological factors that explained vaccine uptake. METHODS: The survey was administered via Amazon Mechanical Turk (MTurk) to United States residents in January 2017, using the Qualtrics platform...
September 7, 2017: Vaccine
https://www.readbyqxmd.com/read/28880856/update-increase-in-human-infections-with-novel-asian-lineage-avian-influenza-a-h7n9-viruses-during-the-fifth-epidemic-china-october-1-2016-august-7-2017
#8
James C Kile, Ruiqi Ren, Liqi Liu, Carolyn M Greene, Katherine Roguski, A Danielle Iuliano, Yunho Jang, Joyce Jones, Sharmi Thor, Ying Song, Suizan Zhou, Susan C Trock, Vivien Dugan, David E Wentworth, Min Z Levine, Timothy M Uyeki, Jacqueline M Katz, Daniel B Jernigan, Sonja J Olsen, Alicia M Fry, Eduardo Azziz-Baumgartner, C Todd Davis
Among all influenza viruses assessed using CDC's Influenza Risk Assessment Tool (IRAT), the Asian lineage avian influenza A(H7N9) virus (Asian H7N9), first reported in China in March 2013,* is ranked as the influenza virus with the highest potential pandemic risk (1). During October 1, 2016-August 7, 2017, the National Health and Family Planning Commission of China; CDC, Taiwan; the Hong Kong Centre for Health Protection; and the Macao CDC reported 759 human infections with Asian H7N9 viruses, including 281 deaths, to the World Health Organization (WHO), making this the largest of the five epidemics of Asian H7N9 infections that have occurred since 2013 (Figure 1)...
September 8, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28877235/genetic-and-antigenic-characterization-of-influenza-a-h3n2-in-cameroon-during-the-2014-2016-influenza-seasons
#9
Gwladys C Monamele, Marie-Astrid Vernet, Mohammed R Njankouo, Kathleen Victoir, Jane Francis Akoachere, Damian Anong, Richard Njouom
The first outbreak of influenza A(H3N2) occurred in 1968 and caused the third flu pandemic of the 20th century. It has affected multiple countries over time. The best strategy to reduce the burden of influenza is through vaccination whose efficacy varies with respect to the circulating strains. This study was performed to better understand the molecular evolution of influenza A(H3N2) and assess vaccine efficacy in Cameroon. Complete sequences of three gene segments were obtained from 2014 to 2016 influenza seasons in Cameroon...
2017: PloS One
https://www.readbyqxmd.com/read/28870977/recommendations-for-prevention-and-control-of-influenza-in-children-2017-2018
#10
(no author information available yet)
This statement updates the recommendations for routine use of the seasonal influenza vaccine and antiviral medications for the prevention and treatment of influenza in children. The American Academy of Pediatrics recommends annual seasonal influenza immunization for everyone 6 months and older, including children and adolescents. Highlights for the upcoming 2017-2018 season include the following:1. Annual universal influenza immunization is indicated with either a trivalent or quadrivalent (no preference) inactivated vaccine;2...
October 2017: Pediatrics
https://www.readbyqxmd.com/read/28855230/live-attenuated-influenza-vaccine-laiv-recent-effectiveness-results-from-the-usa-and-implications-for-laiv-programmes-elsewhere
#11
REVIEW
Richard Pebody, Jim McMenamin, Hanna Nohynek
The USA has a long-standing paediatric influenza vaccination programme, including use of live attenuated influenza vaccine (LAIV). Following US evidence of apparent lack of vaccine effectiveness (VE) of LAIV in 2015/2016, particularly against A(H1N1)pdm09, the USA suspended the use of LAIV in the 2016/2017 season. The UK introduced LAIV for children in 2013/2014 and Finland in 2015/2016. Both countries have since been closely monitoring programme performance. In 2015/2016, the UK and Finland, unlike the USA, found evidence of significant VE of LAIV against laboratory-confirmed influenza...
August 30, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28841201/prevention-and-control-of-seasonal-influenza-with-vaccines-recommendations-of-the-advisory-committee-on-immunization-practices-united-states-2017-18-influenza-season
#12
Lisa A Grohskopf, Leslie Z Sokolow, Karen R Broder, Emmanuel B Walter, Joseph S Bresee, Alicia M Fry, Daniel B Jernigan
This report updates the 2016-17 recommendations of the Advisory Committee on Immunization Practices (ACIP) regarding the use of seasonal influenza vaccines (MMWR Recomm Rep 2016;65[No. RR-5]). Routine annual influenza vaccination is recommended for all persons aged ≥6 months who do not have contraindications. A licensed, recommended, and age-appropriate vaccine should be used.For the 2017-18 season, quadrivalent and trivalent influenza vaccines will be available. Inactivated influenza vaccines (IIVs) will be available in trivalent (IIV3) and quadrivalent (IIV4) formulations...
August 25, 2017: MMWR. Recommendations and Reports: Morbidity and Mortality Weekly Report. Recommendations and Reports
https://www.readbyqxmd.com/read/28792867/influenza-vaccine-effectiveness-in-the-united-states-during-the-2015-2016-season
#13
Michael L Jackson, Jessie R Chung, Lisa A Jackson, C Hallie Phillips, Joyce Benoit, Arnold S Monto, Emily T Martin, Edward A Belongia, Huong Q McLean, Manjusha Gaglani, Kempapura Murthy, Richard Zimmerman, Mary P Nowalk, Alicia M Fry, Brendan Flannery
BACKGROUND: The A(H1N1)pdm09 virus strain used in the live attenuated influenza vaccine was changed for the 2015-2016 influenza season because of its lack of effectiveness in young children in 2013-2014. The Influenza Vaccine Effectiveness Network evaluated the effect of this change as part of its estimates of influenza vaccine effectiveness in 2015-2016. METHODS: We enrolled patients 6 months of age or older who presented with acute respiratory illness at ambulatory care clinics in geographically diverse U...
August 10, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28780977/predominance-of-influenza-a-h3n2-virus-genetic-subclade-3c-2a1-during-an-early-2016-17-influenza-season-in-europe-contribution-of-surveillance-data-from-world-health-organization-who-european-region-to-the-who-vaccine-composition-consultation-for-northern-hemisphere
#14
Angeliki Melidou, Eeva Broberg
During the European 2016/17 influenza season, A(H3N2) viruses have predominated and the majority clustered in genetic subclade 3C.2a1. Genetic analyses showed that circulating viruses have undergone considerable genetic diversification of the haemagglutinin gene from the current vaccine virus A/Hong Kong/4801/2014 (clade 3C.2a), but the antigenic data that is limited by the challenges with the antigenic characterisation of currently circulating A(H3N2) viruses, showed no clear evidence of antigenic change. The recommended A(H3N2) vaccine component for the northern hemisphere 2017/18 influenza season remained unchanged...
September 5, 2017: Vaccine
https://www.readbyqxmd.com/read/28760609/influenza-vaccination-rates-in-children-decline-when-the-live-attenuated-influenza-vaccine-is-not-recommended
#15
Benjamin Fogel, Steven Hicks
BACKGROUND: In 2016 the Centers for Disease Control and Prevention (CDC) recommended against using the live attenuated influenza vaccine (LAIV) for the 2016-2017 influenza season. This recommendation is potentially important for vaccination rates because perceived effectiveness and ease of administration are among the primary determinants of families decisions to vaccinate their children. This investigation sought to determine whether rates of pediatric influenza vaccination changed in a season when the LAIV was not recommended...
July 28, 2017: Vaccine
https://www.readbyqxmd.com/read/28734139/%C3%AE-nfluenza-a-h3n2-genetic-variants-in-vaccinated-patients-in-northern-greece
#16
A Melidou, G Gioula, M Exindari, E Ioannou, K Gkolfinopoulou, T Georgakopoulou, S Tsiodras, A Papa
BACKGROUND: Influenza A(H3N2) viruses predominated during the influenza 2016/2017 season and showed extensive genetic diversification. A high vaccination failure rate was noticed during the 2016/17 season in Greece, especially among the elderly. OBJECTIVES: The scope of the study was to investigate the genetic characteristics of A(H3N2) circulating viruses and viruses detected in vaccinated patients. STUDY DESIGN: Virus samples originated from vaccinated and unvaccinated patients, obtained at the National Influenza Centre for northern Greece...
July 14, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28697522/childhood-vaccination-against-seasonal-influenza-to-reduce-the-overall-burden-of-disease-ethical-perspectives
#17
Kyriakos Martakis, Kruthika Thangavelu, Peter Schröder-Bäck
Introduction Childhood immunisation against seasonal influenza promises to reduce the burden of disease through herd immunity. The option of intranasal vaccination seemed to offer a more acceptable vaccination for children, as they are perceived to be less invasive. Yet, intranasal vaccines have been recently proven not to be as effective as presumed. In Germany, contradictory recommendations of the Standing Committee on Vaccination (STIKO) first, to use and then, in October 2016, not use these vaccines have been issued for the 2016-2017 season, whereas recommendations not to use them were already issued in the USA (CDC, ACIP)...
July 11, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28672275/genetic-divergence-of-influenza-a-h3n2-amino-acid-substitutions-mark-the-beginning-of-the-2016-2017-winter-season-in-israel
#18
Aharona Glatman-Freedman, Yaron Drori, Sharon Alexandra Beni, Nehemya Friedman, Rakefet Pando, Hanna Sefty, Ilana Tal, John McCauley, Galia Rahav, Nathan Keller, Tamy Shohat, Ella Mendelson, Musa Hindiyeh, Michal Mandelboim
BACKGROUND: Influenza vaccine composition is reevaluated each year due to the frequency and accumulation of genetic changes that influenza viruses undergo. The beginning of the 2016-2017 influenza surveillance period in Israel has been marked by the dominance of influenza A(H3N2). OBJECTIVES: To evaluate the type, subtype, genetic evolution and amino acid substitutions of influenza A(H3N2) viruses detected among community patients with influenza-like illness (ILI) and hospitalized patients with respiratory illness in the first weeks of the 2016-2017 influenza season...
June 4, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28662019/update-influenza-activity-in-the-united-states-during-the-2016-17-season-and-composition-of-the-2017-18-influenza-vaccine
#19
Lenee Blanton, Noreen Alabi, Desiree Mustaquim, Calli Taylor, Krista Kniss, Natalie Kramer, Alicia Budd, Shikha Garg, Charisse N Cummings, Jessie Chung, Brendan Flannery, Alicia M Fry, Wendy Sessions, Rebecca Garten, Xiyan Xu, Anwar Isa Abd Elal, Larisa Gubareva, John Barnes, Vivien Dugan, David E Wentworth, Erin Burns, Jacqueline Katz, Daniel Jernigan, Lynnette Brammer
During the 2016-17 influenza season (October 2, 2016-May 20, 2017) in the United States, influenza activity* was moderate. Activity remained low through November, increased during December, and peaked in February nationally, although there were regional differences in the timing of influenza activity. Influenza A(H3N2) viruses predominated through mid-March and were predominant overall for the season, but influenza B viruses were most commonly reported from late March through May. This report summarizes influenza activity in the United States during October 2, 2016-May 20, 2017(†) and updates the previous summary (1)...
June 30, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28542417/interim-estimates-of-the-effectiveness-of-the-influenza-vaccine-against-a-h3n2-influenza-in-adults-in-south-korea-2016-2017-season
#20
Ji Yun Noh, Sooyeon Lim, Joon Young Song, Won Suk Choi, Hye Won Jeong, Jung Yeon Heo, Jacob Lee, Yu Bin Seo, Jin-Soo Lee, Seong Heon Wie, Young Keun Kim, Kyung Hwa Park, Sook-In Jung, Shin Woo Kim, Sun Hee Lee, Han Sol Lee, Young Hoon Yoon, Hee Jin Cheong, Woo Joo Kim
In the 2016-2017 season, the A(H3N2) influenza epidemic presented an unusual early peak pattern compared with past seasons in South Korea. The interim vaccine effectiveness (VE) of influenza vaccination in preventing laboratory-confirmed influenza was estimated using test-negative design through the tertiary hospital-based influenza surveillance system in South Korea. From 1 September, 2016 to 7 January, 2017, adjusted VE of influenza vaccination in preventing laboratory-confirmed A(H3N2) was -52.1% (95% confidence interval [CI], -147...
2017: PloS One
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