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symptom validity neuropsychology

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https://www.readbyqxmd.com/read/28448160/validation-of-anam-for-cognitive-screening-in-a-mixed-clinical-sample
#1
Andrea S Vincent, Tresa M Roebuck-Spencer, L Eugenia Cox-Fuenzalida, Cady Block, James G Scott, Robert Kane
The Automated Neuropsychological Assessment Metrics (ANAM) is a library of computer based tests designed to measure cognitive function at a single time-point or longitudinally for detection of cognitive change. This study sought to validate ANAM as a cognitive screening tool for presence of confirmed neuropsychological diagnosis in an outpatient setting. Retrospective data analysis was conducted for 139 patients referred for outpatient neuropsychological assessment. Clinical diagnosis was made independent of ANAM test results and resulted in a diagnostic mix of both neurologic and psychologic etiologies...
April 27, 2017: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/28431035/medical-symptom-validity-test-performance-following-moderate-severe-traumatic-brain-injury-expectations-based-on-orientation-log-classification
#2
Stephen N Macciocchi, Ronald T Seel, Angela Yi, Sarah Small
Objective: This study examined performance on the Medical Symptom Validity test (MSVT) during acute rehabilitation for moderate-severe traumatic brain injury (TBI) stratified by Orientation Log (O-Log) scores. Method: Participants were 77 prospectively enrolled persons who sustained moderate-severe TBI and were acutely hospitalized secondary to the cognitive, medical and physical sequelae of their TBI. Participants were administered neuropsychological metrics, the O-Log and the MSVT a mean of 44 days post injury...
May 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28430849/performance-and-symptom-validity-testing-as-a-function-of-medical-board-evaluation-in-u-s-military-service-members-with-a-history-of-mild-traumatic-brain-injury
#3
Patrick Armistead-Jehle, Wesley R Cole, Robert L Stegman
Objective: The study was designed to replicate and extend pervious findings demonstrating the high rates of invalid neuropsychological testing in military service members (SMs) with a history of mild traumatic brain injury (mTBI) assessed in the context of a medical evaluation board (MEB). Method: Two hundred thirty-one active duty SMs (61 of which were undergoing an MEB) underwent neuropsychological assessment. Performance validity (Word Memory Test) and symptom validity (MMPI-2-RF) test data were compared across those evaluated within disability (MEB) and clinical contexts...
April 20, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28415909/detecting-coached-neuropsychological-dysfunction-a-simulation-experiment-regarding-mild-traumatic-brain-injury
#4
Lily Lau, Michael R Basso, Eduardo Estevis, Ashley Miller, Douglas M Whiteside, Dennis Combs, Timothy J Arentsen
OBJECTIVE: Performance validity tests (PVTs) and symptom validity tests (SVTs) are often administered during neuropsychological evaluations. Examinees may be coached to avoid detection by measures of response validity. Relatively little research has evaluated whether graduated levels of coaching has differential effects upon PVT and SVT performance. Accordingly, the present experiment evaluated the effect of graduated levels of coaching upon the classification accuracy of commonly used PVTs and SVTs and the currently accepted criterion of failing two or more PVTs or SVTs...
April 18, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28391774/exploring-the-sensitivity-of-the-personality-assessment-inventory-symptom-validity-tests-in-detecting-response-bias-in-a-mixed-neuropsychological-outpatient-sample
#5
Owen J Gaasedelen, Douglas M Whiteside, Michael Basso
OBJECTIVE: Few studies have evaluated the symptom validity tests (SVTs) within the Personality Assessment Inventory (PAI) in a neuropsychological assessment context. Accordingly, the present study explored the accuracy of PAI SVTs in identifying exaggerated cognitive dysfunction in a mixed sample of outpatients referred for neuropsychological assessment. METHOD: Participants who failed two or more Performance Validity Tests (PVTs) were classified as having exaggerated cognitive dysfunction (n = 49)...
April 10, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28385127/retinal-nerve-fiber-layer-thickness-and-neuropsychiatric-manifestations-in-systemic-lupus-erythematosus
#6
S Shulman, R Shorer, J Wollman, G Dotan, D Paran
Background Cognitive impairment is frequent in systemic lupus erythematosus. Atrophy of the corpus callosum and hippocampus have been reported in patients with systemic lupus erythematosus, and diffusion tensor imaging studies have shown impaired white matter integrity, suggesting that white matter damage in systemic lupus erythematosus may underlie the cognitive impairment as well as other neuropsychiatric systemic lupus erythematosus manifestations. Retinal nerve fiber layer thickness, as assessed by optical coherence tomography, has been suggested as a biomarker for white matter damage in neurologic disorders such as multiple sclerosis, Alzheimer's disease and Parkinson's disease...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28365748/an-intervention-to-decrease-the-occurrence-of-invalid-data-on-neuropsychological-evaluation
#7
Michael David Horner, Travis H Turner, Kathryn K VanKirk, John H Denning
Objective: This study tested whether patients who were given a handout based on deterrence theory, immediately prior to evaluation, would provide invalid data less frequently than patients who were simply given an informational handout. Method: All outpatients seen for clinical evaluation in a VA Neuropsychology Clinic were randomly given one of the two handouts immediately prior to evaluation. The "Intervention" handout emphasized the importance of trying one's hardest, explicitly listed consequences of valid and invalid responding and asked patients to sign and initial it...
March 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28353391/validity-of-self-reported-concentration-and-memory-problems-relationship-with-neuropsychological-assessment-and-depression
#8
Rosemarie M Bowler, Shane W Adams, Ralf Schwarzer, Vihra V Gocheva, Harry A Roels, Yangho Kim, Catherine L Kircos, Chris W Wright, Michelle Colledge, George Bollweg, Danelle T Lobdell
BACKGROUND: This study investigated the validity of self-reported concentration and memory problems (CMP) in residents environmentally exposed to manganese (Mn). METHOD: Self-report of CMP from a health questionnaire (HQ) and the Symptom Checklist-90-Revised (SCL-90-R) was compared to neuropsychological assessment (Trails A&B; Digit Span; Digit Symbol; Similarities; Auditory Consonant Trigrams, ACT; NAB Memory; Rey-Osterrieth, Rey-O, Delayed). Participants included 146 residents from Ohio exposed to air-Mn, with a modeled average concentration of 0...
March 29, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28207863/identification-of-age-dependent-motor-and-neuropsychological-behavioural-abnormalities-in-a-mouse-model-of-mucopolysaccharidosis-type-ii
#9
Hélène F E Gleitz, Claire O'Leary, Rebecca J Holley, Brian W Bigger
Severe mucopolysaccharidosis type II (MPS II) is a progressive lysosomal storage disease caused by mutations in the IDS gene, leading to a deficiency in the iduronate-2-sulfatase enzyme that is involved in heparan sulphate and dermatan sulphate catabolism. In constitutive form, MPS II is a multi-system disease characterised by progressive neurocognitive decline, severe skeletal abnormalities and hepatosplenomegaly. Although enzyme replacement therapy has been approved for treatment of peripheral organs, no therapy effectively treats the cognitive symptoms of the disease and novel therapies are in development to remediate this...
2017: PloS One
https://www.readbyqxmd.com/read/28187217/electrophysiological-cognitive-and-clinical-profiles-of-at-risk-mental-state-the-longitudinal-minds-in-transition-mint-study
#10
Rebbekah J Atkinson, W Ross Fulham, Patricia T Michie, Philip B Ward, Juanita Todd, Helen Stain, Robyn Langdon, Renate Thienel, Georgie Paulik, Gavin Cooper, Ulrich Schall
The onset of schizophrenia is typically preceded by a prodromal period lasting several years during which sub-threshold symptoms may be identified retrospectively. Clinical interviews are currently used to identify individuals who have an ultra-high risk (UHR) of developing a psychotic illness with a view to provision of interventions that prevent, delay or reduce severity of future mental health issues. The utility of bio-markers as an adjunct in the identification of UHR individuals is not yet established...
2017: PloS One
https://www.readbyqxmd.com/read/28122474/screening-for-neurocognitive-impairment-in-hiv-positive-adults-aged-50-years-and-older-montreal-cognitive-assessment-relates-to-self-reported-and-clinician-rated-everyday-functioning
#11
P L Fazeli, K B Casaletto, E Paolillo, R C Moore, D J Moore, The Hnrp Group
As the HIV+ population ages, the risk for and need to screen for HIV-associated neurocognitive disorders (HAND) increases. The aim of this study is to determine the utility and ecological validity of the Montreal Cognitive Assessment (MoCA) among older HIV+ adults. A total of 100 HIV+ older adults aged 50 years or over completed a comprehensive neuromedical and neurocognitive battery, including the MoCA and several everyday functioning measures. The receiver operating characteristic curve indicates ≤26 as the optimal cut-off balancing sensitivity (84...
January 26, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28114873/cogniphobia-in-mild-traumatic-brain-injury
#12
Noah D Silverberg, Grant L Iverson, William Panenka
Cogniphobia refers to avoidance of mental exertion out of a fear of developing or exacerbating a headache. Headaches are very common after mild traumatic brain injury (mTBI) and often become chronic. Cogniphobia is hypothesized to contribute to poor cognitive test performance and persistent disability in some patients with mTBI. Eighty patients with mTBI and post-traumatic headaches were recruited from specialty outpatient clinics. They completed a battery of questionnaires (including a cogniphobia scale) and neuropsychological tests (the National Institutes of Health Toolbox Cognition Battery and the Medical Symptom Validity Test) at 2-3 months post injury, in a cross-sectional design...
February 27, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28078966/visual-and-cross-modal-cues-increase-the-identification-of-overlapping-visual-stimuli-in-balint-s-syndrome
#13
Daniela D'Imperio, Michele Scandola, Valeria Gobbetto, Cristina Bulgarelli, Matteo Salgarello, Renato Avesani, Valentina Moro
INTRODUCTION: Cross-modal interactions improve the processing of external stimuli, particularly when an isolated sensory modality is impaired. When information from different modalities is integrated, object recognition is facilitated probably as a result of bottom-up and top-down processes. The aim of this study was to investigate the potential effects of cross-modal stimulation in a case of simultanagnosia. METHOD: We report a detailed analysis of clinical symptoms and an (18)F-fluorodeoxyglucose (FDG) brain positron emission tomography/computed tomography (PET/CT) study of a patient affected by Balint's syndrome, a rare and invasive visual-spatial disorder following bilateral parieto-occipital lesions...
January 12, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28043193/adhd-traits-in-german-school-aged-children
#14
Yoanna Schulz-Zhecheva, Manuel Voelkle, André Beauducel, Nadja Buch, Christian Fleischhaker, Stephan Bender, Christopher W N Saville, Monica Biscaldi, Christoph Klein
OBJECTIVE: The Strengths and Weaknesses of ADHS-Symptoms and Normal Behavior (SWAN) Scale has been developed to support the dimensional assessment of ADHD symptoms by capturing variance on both poles of the ADHD continuum. The present study provides the first validation of the German version of SWAN (SWAN-DE). METHOD: Based on a sample of N1 = 343 children from the general population and N2 = 62 children with ADHD, both aged between 8 and 18 years, normality, internal consistency, test-retest reliability, and different validity indices were examined...
January 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28012996/life-events-salivary-cortisol-and-cognitive-performance-in-nondemented-subjects-a-population-based-study
#15
Sami Ouanes, Enrique Castelao, Sirak Gebreab, Armin von Gunten, Martin Preisig, Julius Popp
Older people are particularly exposed to stressful events, known to activate the hypothalamus-pituitary-adrenal axis resulting in increased cortisol levels. High cortisol has been associated with deleterious effects on cognition. We hypothesized that stressful life events could increase cortisol secretion leading to cognitive impairment. A cross-sectional analysis was conducted using data from Colaus/PsyColaus, a longitudinal population-based study among Lausanne residents. Salivary cortisol samples were obtained from 796 nondemented subjects aged at least 65...
March 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28009725/cognitive-decline-and-dementia-in-down-syndrome
#16
Rosalyn Hithersay, Sarah Hamburg, Bernice Knight, André Strydom
PURPOSE OF REVIEW: Alzheimer's disease is most likely universal in older individuals with Down syndrome, due to having three copies of the amyloid precursor protein gene, resulting in amyloid-beta plaque deposition. Down syndrome is an important population in which to consider clinical trials of treatments to prevent or delay the development of dementia. However, assessment of subtler cognitive changes is challenging due to the presence of intellectual disability. RECENT FINDINGS: Recent research confirmed that older adults with Down syndrome often present with cognitive decline: more than 80% may experience dementia by age 65 years...
March 2017: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28009651/a-review-of-cognitive-screening-tools-in-cancer
#17
Elie Isenberg-Grzeda, Helen Huband, Henry Lam
PURPOSE OF REVIEW: Cancer-related cognitive impairment (CRCI) is highly prevalent, and assessment of cognition is crucial in providing optimal cancer care. Neuropsychological assessment (NPA) can be lengthy and expensive. Cognitive screening tools are plenty but validity has not been thoroughly studied for use in cancer patients. RECENT FINDINGS: Our search of the recent literature revealed that the Montreal Cognitive Assessment, Mini-Mental State Examination, and Clock Draw Test were the most frequently studied objective screening tools...
March 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/27998904/word-memory-test-performance-across-cognitive-domains-psychiatric-presentations-and-mild-traumatic-brain-injury
#18
Jared A Rowland, Holly M Miskey, Timothy W Brearly, Sarah L Martindale, Robert D Shura
OBJECTIVE: The current study addressed two aims: (i) determine how Word Memory Test (WMT) performance relates to test performance across numerous cognitive domains and (ii) evaluate how current psychiatric disorders or mild traumatic brain injury (mTBI) history affects performance on the WMT after excluding participants with poor symptom validity. METHOD: Participants were 235 Iraq and Afghanistan-era veterans (Mage = 35.5) who completed a comprehensive neuropsychological battery...
December 19, 2016: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/27936937/driving-in-mild-cognitive-impairment-the-role-of-depressive-symptoms
#19
Ion N Beratis, Nikos Andronas, Dionysia Kontaxopoulou, Stella Fragkiadaki, Dimosthenis Pavlou, John Papatriantafyllou, Alexandra Economou, George Yannis, Sokratis G Papageorgiou
OBJECTIVES: Previous studies indicate a negative association between depression and driving fitness in the general population. Our goal was to cover a gap in the literature and to explore the link between depressive symptoms and driving behavior in individuals with mild cognitive impairment (MCI) through the use of a driving simulator experiment. METHODS: Twenty-four individuals with MCI (mean age = 67.42, SD = 7.13) and 23 cognitively healthy individuals (mean age = 65...
December 12, 2016: Traffic Injury Prevention
https://www.readbyqxmd.com/read/27903334/applying-an-evidence-based-assessment-model-to-identify-students-at-risk-for-perceived-academic-problems-following-concussion
#20
Danielle M Ransom, Alison R Burns, Eric A Youngstrom, Christopher G Vaughan, Maegan D Sady, Gerard A Gioia
OBJECTIVES: The aim of this study was to demonstrate the utility of an evidence-based assessment (EBA) model to establish a multimodal set of tools for identifying students at risk for perceived post-injury academic problems. METHODS: Participants included 142 students diagnosed with concussion (age: M=14.95; SD=1.80; 59% male), evaluated within 4 weeks of injury (median=16 days). Demographics, pre-injury history, self- and parent-report measures assessing symptom severity and executive functions, and cognitive test performance were examined as predictors of self-reported post-injury academic problems...
November 2016: Journal of the International Neuropsychological Society: JINS
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