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Folate nutrition

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https://www.readbyqxmd.com/read/29446079/dietary-intake-of-nutrients-involved-in-one-carbon-metabolism-and-risk-of-urothelial-cell-carcinoma-a-prospective-cohort-study
#1
Pierre-Antoine Dugué, Maree T Brinkman, Allison M Hodge, Julie K Bassett, Damien Bolton, Anthony Longano, John L Hopper, Melissa C Southey, Dallas R English, Roger L Milne, Graham G Giles
Nutrients involved in one-carbon metabolism may play a role in carcinogenesis through DNA replication, repair and methylation mechanisms. Most studies on urothelial cell carcinoma (UCC) have focused on folate. We sought to examine the association between B-group vitamins and methionine intake and UCC risk, overall and by subtype, and to test whether these associations are different for population subgroups whose nutritional status may be compromised. We followed participants in the Melbourne Collaborative Cohort Study (N=41,513) for over 20 years, and observed 500 UCC cases (89% originating in the bladder; superficial: 279, invasive: 221)...
February 15, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29433770/acid-folic-and-pregnancy-a-mandatory-supplementation
#2
Morgane Valentin, Perrine Coste Mazeau, Michel Zerah, Pierre François Ceccaldi, Alexandra Benachi, Dominique Luton
Neural tube defects (NTD) occur in 0.5 to 2 per 1000 pregnancies with various handicaps for the affected child. It is now well established that folic acid deficiency (absolute or relative) is a predisposing factor to this type of malformation. Several randomized controlled trials showed that high-dose folic acid (4mg) is an essential factor for prevention of neural tube defects recurrence and significantly prevents the first occurrence of neural tube defects with a lower dose (0.4mg). Other etiologies can favor the occurrence of NTD such as MTHFR polymorphism, some antiepileptic therapies, obesity and pregestational mellitus diabetes...
February 9, 2018: Annales D'endocrinologie
https://www.readbyqxmd.com/read/29429126/individual-susceptibility-to-arsenic-induced-diseases-the-role-of-host-genetics-nutritional-status-and-the-gut-microbiome
#3
REVIEW
Liang Chi, Bei Gao, Pengcheng Tu, Chih-Wei Liu, Jingchuan Xue, Yunjia Lai, Hongyu Ru, Kun Lu
Arsenic (As) contamination in water or food is a global issue affecting hundreds of millions of people. Although As is classified as a group 1 carcinogen and is associated with multiple diseases, the individual susceptibility to As-related diseases is highly variable, such that a proportion of people exposed to As have higher risks of developing related disorders. Many factors have been found to be associated with As susceptibility. One of the main sources of the variability found in As susceptibility is the variation in the host genome, namely, polymorphisms of many genes involved in As transportation, biotransformation, oxidative stress response, and DNA repair affect the susceptibility of an individual to As toxicity and then influence the disease outcomes...
February 10, 2018: Mammalian Genome: Official Journal of the International Mammalian Genome Society
https://www.readbyqxmd.com/read/29415587/an-evaluation-of-nutritional-and-vasoactive-stimulants-as-risk-factors-for-gastroschisis-a-pilot-study
#4
Jean R Goodman, Jennifer D Peck, Alessandra Landmann, Marvin Williams, Andrew Elimian
OBJECTIVE: The objective of this study is to evaluate poor maternal nutrition, environmental exposures and vasoactive stimulants as potential risk factors for gastroschisis. METHODS: A case-control study was conducted among singleton pregnancies diagnosed in a tertiary teaching hospital in a 22-month period. Cases of gastroschisis were matched to controls at the time of diagnosis by race and maternal age. Demographics, periconceptual exposures, nutritional biomarkers, and illicit drug hair analysis were evaluated...
February 7, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29413007/malnutrition-in-gastrointestinal-disorders-detection-and-nutritional-assessment
#5
REVIEW
Khursheed N Jeejeebhoy, Donald R Duerksen
All patients with significant gastrointestinal disease should be clinically assessed for protein calorie malnutrition by using the Subjective Global Assessment. Blood tests for anemia, electrolytes, calcium, phosphorus, magnesium, ferritin, vitamin B 12 , and folate should be considered for assessment of major micronutrients. Where malabsorption or inflammatory bowel disease is diagnosed, bone mineral density using dual beam x-ray absorptiometry, 25-OH vitamin D levels, and measurement of other vitamins and trace elements should be considered...
March 2018: Gastroenterology Clinics of North America
https://www.readbyqxmd.com/read/29407937/the-contribution-of-minor-folates-to-the-total-vitamin-b9-content-of-infant-formula-and-clinical-nutrition-products
#6
Esther Campos-Giménez, Sylvie Bénet, Yannick Oguey, Frédéric Martin, Karine Redeuil
In the present study an optimization of trienzyme treatment combining α-amylase, protease and γ-carboxy peptidase allowing complete sample preparation within a working day for the analysis of vitamin B9 (folate) in infant formula and adult/pediatric nutritional products is presented. The optimized sample preparation was applied to a set of samples representing most of the products in the marketplace. Results on Standard Reference Material 1849a were well in agreement with certified values. The main contributor to total folate was folic acid, 5-methyl-tetrahydrofolate was the only minor contributor in milk-based products...
May 30, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29391590/measures-of-low-food-variety-and-poor-dietary-quality-in-a-cross-sectional-study-of-london-school-children
#7
Cel Evans, J Hutchinson, M S Christian, N Hancock, J E Cade
BACKGROUND/OBJECTIVES: The use of simple screening tools to measure nutritional adequacy in a public health context in developed countries are currently lacking. We explore the relationship between food variety and nutrient intake of London school children using a simple tool with potential use for screening for inadequate diets. SUBJECTS/METHODS: A cross-sectional survey was carried out in 2010. The survey included 2579 children aged 7-10 years in 52 primary schools in East London in the United Kingdom...
February 1, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29379142/erythrocyte-folate-serum-vitamin-b12-and-hearing-loss-in-the-2003-2004-national-health-and-nutrition-examination-survey-nhanes
#8
Edmond K Kabagambe, Loren Lipworth, Robert F Labadie, Linda J Hood, David O Francis
BACKGROUND/OBJECTIVES: Studies based on food frequency questionnaires suggest that folate and vitamin B12 intake could protect against hearing loss. We investigated whether erythrocyte folate and serum vitamin B12 levels are independently associated with hearing loss in humans. SUBJECTS/METHODS: Participants in the 2003-2004 US National Health and Nutrition Examination Survey who had data on hearing, folate, and vitamin B12 levels were included. Pure-tone average (PTA) at 0...
January 29, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29377209/should-vitamin-b12-status-be-considered-in-assessing-risk-of-neural-tube-defects
#9
Anne M Molloy
There is a strong biological premise for including vitamin B12 with folic acid in strategies to prevent neural tube defects (NTDs), due to the closely interlinked metabolism of these two vitamins. For example, reduction of B12 deficiency among women of reproductive age could enhance the capacity of folic acid to prevent NTDs by optimizing the cellular uptake and utilization of natural folate cofactors. Vitamin B12 might also have an independent role in NTD prevention, such that adding it in fortification programs might be more effective than fortifying with folic acid alone...
January 29, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29367733/skipping-breakfast-is-associated-with-lower-diet-quality-in-young-us-children
#10
Samantha A Ramsay, Tama D Bloch, Barbara Marriage, Lenka H Shriver, Colleen K Spees, Christopher A Taylor
BACKGROUND/OBJECTIVES: Breakfast consumption has been shown to impact children's growth and development, but the influence of breakfast skipping on total daily intakes is not known. The purpose of this study was to examine the differences in nutritional intakes and food consumption between children who consume breakfast versus those who do not. SUBJECTS/METHODS: Dietary recall data were assessed for 2-year-old to 5-year-old children (n = 3443) and 6-year-old to 12-year-old children (n = 5147) from NHANES 2005-2012...
January 24, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29364915/helicobacter-pylori-moderates-the-association-between-5-mthf-concentration-and-cognitive-function-in-older-adults
#11
Andrew N Berrett, Shawn D Gale, Lance D Erickson, Bruce L Brown, Dawson W Hedges
OBJECTIVE: To explore potential interactions between folate-cycle factors and Helicobacter pylori seropositivity in the prediction of cognitive function. METHODS: We used data obtained from the 1999-2000 continuous National Health and Nutrition Examination Survey produced by the United States' Centers for Disease Control and Prevention. Using Ordinary Least Squares regression, we tested for associations between multiple folate-cycle factors, Helicobacter pylori seropositivity, and cognitive function assessed by the digit symbol coding subtest of the Wechsler Adult Intelligence Scale-III...
2018: PloS One
https://www.readbyqxmd.com/read/29360850/a-prospective-study-of-frequency-of-eating-restaurant-prepared-meals-and-subsequent-9-year-risk-of-all-cause-and-cardiometabolic-mortality-in-us-adults
#12
Ashima K Kant, Barry I Graubard
Restaurant prepared foods are known to be energy-dense and high in fat and sodium, but lower in protective nutrients. There is evidence of higher risk of adiposity, type II diabetes, and heart disease in frequent consumers of restaurant meals. However, the risk of mortality as a long-term health consequence of frequent consumption of restaurant meals has not been examined. We examined the prospective risk of all-cause and coronary heart disease, cerebrovascular disease and diabetes (cardiometabolic) mortality in relation to frequency of eating restaurant prepared meals in a national cohort...
2018: PloS One
https://www.readbyqxmd.com/read/29359438/mothers-groups-enrich-diet-and-culture-through-promoting-traditional-quichua-foods
#13
Marion L Roche, Lorena Ambato, Julieta Sarsoza, Harriet V Kuhnlein
Indigenous Peoples in Latin America bear a disproportionate burden of undernutrition, yet traditional foods, including wild leafy greens, can contribute nutritional value to diets. As part of a community nutrition intervention using local foods in highland Tungurahua, Ecuador, mothers' groups promoted the consumption of wild leafy greens through community cooking clubs and recipe competitions at local fairs. The objective was to assess the social, cultural, and nutritional potential of a mothers' club intervention that promoted 2 indigenous greens (stinging nettle/Urtica dioica L...
November 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29358479/advocacy-for-improving-nutrition-in-the-first-1000-days-to-support-childhood-development-and-adult-health
#14
Sarah Jane Schwarzenberg, Michael K Georgieff
Maternal prenatal nutrition and the child's nutrition in the first 2 years of life (1000 days) are crucial factors in a child's neurodevelopment and lifelong mental health. Child and adult health risks, including obesity, hypertension, and diabetes, may be programmed by nutritional status during this period. Calories are essential for growth of both fetus and child but are not sufficient for normal brain development. Although all nutrients are necessary for brain growth, key nutrients that support neurodevelopment include protein; zinc; iron; choline; folate; iodine; vitamins A, D, B6, and B12; and long-chain polyunsaturated fatty acids...
January 22, 2018: Pediatrics
https://www.readbyqxmd.com/read/29356956/paediatric-patients-with-coeliac-disease-on-a-gluten-free-diet-nutritional-adequacy-and-macro-and-micronutrient-imbalances
#15
REVIEW
Alison Sue, Kate Dehlsen, Chee Y Ooi
PURPOSE OF REVIEW: A strict, lifelong gluten-free diet is the cornerstone for management of coeliac disease. Elimination of gluten from the diet may be associated with nutritional imbalance; however, the completeness of this diet in energy and macro- and micronutrients in children is not well described. Understanding the nutritional adequacy of the gluten-free diet in children during this critical period of growth and development when dietary intake is strongly influential is important...
January 22, 2018: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29343135/genetic-polymorphisms-in-folate-metabolism-as-risk-for-down-syndrome-in-the-southern-china
#16
Lin Jiajin, Cao Shuyan, Wu Ying, Chen Junxiao, Wang Xiudi
OBJECTIVE: To assess the association between maternal gene polymorphisms of the enzymes involved in folate metabolism and the risk of having a Down syndrome (DS) offspring in southern China mothers. METHODS: Gene polymorphisms in folate metabolizing and the levels of homocysteine (HCY) were analyzed in 84 southern China mothers with DS babies (the case group) and 120 healthy mothers (the control group). Methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) and A1298C (rs1801131), methionine synthase (MTR) A2756G (rs1805087), and methionine synthase reductase (MTRR) A66G (rs1801394) were studied...
January 17, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29317006/secular-trends-in-regional-differences-in-nutritional-biomarkers-and-self-reported-dietary-intakes-among-american-adults-national-health-and-nutrition-examination-survey-nhanes-1988-1994-to-2009-2010
#17
Ashima K Kant, Barry I Graubard
OBJECTIVE: To understand the contribution of regional differentials in dietary exposures to regional gradients in health, we examined 20-year trends in the association of US census region of residence with nutritional biomarkers and dietary intakes of American adults. DESIGN: Observational. SETTING: The biomarker and 24 h dietary recall data were from the National Health and Nutrition Examination Surveys (NHANES) conducted during 1988-1994 and 1999-2010...
January 10, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29316987/diet-nutrition-and-the-ageing-brain-current-evidence-and-new-directions
#18
Katie Moore, Catherine F Hughes, Mary Ward, Leane Hoey, Helene McNulty
Globally populations are ageing. By 2050, it is estimated that there will be two billion people aged 60 years or over, of which 131 million are projected to be affected by dementia, while depression is predicted to be the second leading cause of disability worldwide by 2020. Preventing or delaying the onset of these disorders should therefore be a public health priority. There is some evidence linking certain dietary patterns, particularly the Mediterranean diet, with a reduced risk of dementia and depression...
January 10, 2018: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/29316941/homocysteine-folate-hs-c-reactive-protein-tumor-necrosis-factor-alpha-and-inflammatory-proteins-are-these-biomarkers-related-to-nutritional-status-and-cardiovascular-risk-in-childhood-onset-systemic-lupus-erythematosus
#19
Roberta Garcia Salomão, Luciana Martins de Carvalho, Clarice Izumi, Érika Silva Czernisz, José César Rosa, Sonir Roberto Rauber Antonini, Ana Carolina Bueno, Maria Olímpia Ribeiro do Vale Almada, Carolina de Almeida Coelho-Landell, Alceu Afonso Jordão, Virgínia Paes Leme Ferriani, Jacqueline Pontes Monteiro
BACKGROUND: Childhood-onset systemic lupus erythematosus (c-SLE) is a chronic autoimmune disease which increases cardiovascular risk factors (CRF) such as elevated homocysteine, TNF-α, and hs-C reactive protein. METHODS: We evaluated BMI, waist circumference (WC), 24-h recalls, SLEDAI-2 K, SLICC/ACR-DI, serum levels of homocysteine, folate, TNF-α, hs-C reactive protein, lipid profile, proteomic data, and duration of corticosteroid therapy in 19 c-SLE and 38 healthy volunteers...
January 9, 2018: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/29316699/arizona-registered-dietitians-show-gaps-in-knowledge-of-bean-health-benefits
#20
Donna M Winham, Andrea M Hutchins, Sharon V Thompson, Mariah K Dougherty
Registered Dietitians (RDs) promote nutrition practices and policies and can influence food consumption patterns to include nutrient dense foods such as beans. Although many evidence-based health benefits of bean consumption (e.g., cholesterol reduction, glycemic control) have been demonstrated, there is limited research on the knowledge, attitudes, and perceptions of RDs regarding the inclusion of beans in a healthy diet. To fill this existing research gap, this cross-sectional survey explored the perceptions, knowledge, and attitudes of 296 RDs in Arizona, USA, toward beans...
January 8, 2018: Nutrients
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