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Folate nutrition

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https://www.readbyqxmd.com/read/27905104/biomarkers-of-folate-and-vitamin-b12-and-breast-cancer-risk-report-from-the-epic-cohort
#1
M Matejcic, J de Batlle, C Ricci, C Biessy, F Perrier, I Huybrechts, E Weiderpass, Boutron-Mc Ruault, C Cadeau, M His, D G Cox, H Boeing, R T Fortner, R Kaaks, P Lagiou, A Trichopoulou, V Benetou, R Tumino, S Panico, S Sieri, D Palli, F Ricceri, H B Bueno-de-Mesquita, G Skeie, P Amiano, M J Sánchez, M D Chirlaque, A Barricarte, J R Quirós, G Buckland, C H van Gils, P H Peeters, T J Key, E Riboli, B Gylling, A Zeleniuch-Jacquotte, M J Gunter, I Romieu, V Chajès
Epidemiological studies have reported inconsistent findings for the association between B vitamins and breast cancer (BC) risk. We investigated the relationship between biomarkers of folate and vitamin B12 and the risk of BC in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Plasma concentrations of folate and vitamin B12 were determined in 2,491 BC cases individually matched to 2,521 controls among women who provided baseline blood samples. Multivariable logistic regression models were used to estimate odds ratios by quartiles of either plasma B vitamin...
December 1, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27901035/homocysteine-reducing-b-vitamins-and-ischemic-heart-disease-a-separate-sample-mendelian-randomization-analysis
#2
J V Zhao, C M Schooling
BACKGROUND/OBJECTIVES: Observationally, homocysteine is positively associated with ischemic heart disease (IHD) and unhealthy lipids; folate and vitamin B12, which reduce homocysteine, are associated with lower IHD risk and healthy lipids. Randomized controlled trials have shown no benefits of folate and vitamin B12 for IHD. To clarify the role of these potential targets of intervention in IHD we assessed how genetically determined homocysteine, folate and vitamin-B12-affected IHD and lipids...
November 30, 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27899367/intake-of-key-micronutrients-and-food-groups-in-patients-with-late-stage-age-related-macular-degeneration-compared-with-age-sex-matched-controls
#3
Bamini Gopinath, Gerald Liew, Joanna Russell, Victoria Cosatto, George Burlutsky, Paul Mitchell
BACKGROUND: Knowledge of the risk factor profile of patients presenting with late-stage age-related macular degeneration (AMD) could help identify the most frequent modifiable AMD precursors among people who are referred for treatment. We aimed to assess dietary behaviours by comparing adjusted mean intakes of micronutrients and major food groups (fruits, vegetables, fish) among patients with AMD and a sample of age-sex-matched controls. METHODS: Cross-sectional analysis of 480 late AMD cases and 518 population-based age-sex-matched controls with no AMD signs...
November 29, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27896937/effect-of-tailored-dietary-guidance-for-pregnant-women-on-nutritional-status-a-double-cohort-study
#4
Megumi Haruna, Mie Shiraishi, Masayo Matsuzaki, Yuko Yatsuki, SeonAe Yeo
This double cohort study aimed to evaluate the effect of tailored dietary guidance for pregnant women on dietary intake, nutritional status, and infant birth weight. Healthy pregnant women were recruited at an antenatal clinic during two phases over 2 years. The historical controls were analyzed a year prior to the intervention group. In both groups, data were collected at 19-26 gestational weeks (baseline) and at 34-37 gestational weeks (outcome measurement). The intervention included the following: (a) assessments of maternal dietary nutritional intake using the brief self-administered diet history questionnaire, (b) individual feedback based on the assessments of maternal nutritional status, (c) tailored guidance for a healthy diet, (d) original cooking recipes, and (e) goal sharing...
November 29, 2016: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/27889145/potential-probiotic-pichia-kudriavzevii-strains-and-their-ability-to-enhance-folate-content-of-traditional-cereal-based-african-fermented-food
#5
Anna Greppi, Fabien Saubade, Cristian Botta, Christèle Humblot, Jean-Pierre Guyot, Luca Cocolin
With the aim of selecting starter cultures with interesting probiotic potential and with the ability to produce folate in a food matrix, yeast strains isolated from fermented cereal-based African foods were investigated. A total of 93 yeast strains were screened for their tolerance to pH 2 and 0.3% of bile salts. Pichia kudriavzevii isolates gave the best results. Selected P. kudriavzevii strains were tested for survival to the simulated human digestion and for adhesion to Caco-2 cells. Moreover, presence of folate biosynthesis genes was verified and production of extra and intra-cellular folate determined during growth in culture medium...
April 2017: Food Microbiology
https://www.readbyqxmd.com/read/27876556/homocysteine-and-disease-causal-associations-or-epiphenomenons
#6
REVIEW
Luciana Hannibal, Henk J Blom
Nutritional and genetic deficiencies of folate and vitamin B12 lead to elevation of cellular homocysteine (Hcy), which translates in increased plasma Hcy. The sources and role of elevated plasma Hcy in pathology continues to be a subject of intense scientific debate. Whether a cause, mediator or marker, little is known about the molecular mechanisms and interactions of Hcy with cellular processes that lead to disease. The use of folic acid reduces the incidence of neural tube defects, but the effect of Hcy-lowering interventions with folic acid in cardiovascular disease and cognitive impairment remains controversial...
November 19, 2016: Molecular Aspects of Medicine
https://www.readbyqxmd.com/read/27876555/one-carbon-metabolism-and-epigenetics
#7
REVIEW
Simonetta Friso, Silvia Udali, Domenica De Santis, Sang-Woon Choi
The function of one-carbon metabolism is that of regulating the provision of methyl groups for biological methylation reactions including that of DNA and histone proteins. Methylation at specific sites into the DNA sequence and at histone tails are among the major epigenetic feature of mammalian genome for the regulation of gene expression. The enzymes within one-carbon metabolism are dependent from a number of vitamins or nutrients that serve either as co-factors or methyl acceptors or donors among which folate, vitamin B12, vitamin B6, betaine, choline and methionine have a major role...
November 19, 2016: Molecular Aspects of Medicine
https://www.readbyqxmd.com/read/27867449/exploring-the-potential-of-indigenous-foods-to-address-hidden-hunger-nutritive-value-of-indigenous-foods-of-santhal-tribal-community-of-jharkhand-india
#8
Suparna Ghosh-Jerath, Archna Singh, Melina S Magsumbol, Preeti Kamboj, Gail Goldberg
Traditional foods of indigenous communities can be explored as a sustainable means of addressing undernutrition. Our study aimed at identifying indigenous foods of the Santhal tribal community of Godda district of Jharkhand, India, assessing their nutritive value, and appraising their potential role in addressing hidden hunger. A cross-sectional survey using qualitative methods like focus group discussions with women of childbearing age (15-49 years), adult males, and elderly people was conducted for food identification...
October 1, 2016: Journal of Hunger & Environmental Nutrition
https://www.readbyqxmd.com/read/27855294/evidence-for-the-vitamin-d-hypothesis-the-nhanes-iii-extended-mortality-follow-up
#9
Ahmad H Daraghmeh, Monica L Bertoia, Mazen O Al-Qadi, Abdulrahman M Abdulbaki, Mary B Roberts, Charles B Eaton
BACKGROUND AND AIMS: Emerging evidence suggests that low levels of vitamin D may be an important risk factor for multiple chronic diseases and mortality, but the evidence is mixed. Vitamin D levels are associated with sun exposure, diet, and metabolic status. One potential explanation for the lack of consistent findings amongst various studies is that low vitamin levels may be associated with poor diets or other risk factors that we were not adequately controlled for in different analyses...
April 9, 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27845713/novel-approaches-to-investigate-one-carbon-metabolism-and-related-b-vitamins-in-blood-pressure
#10
REVIEW
Amy McMahon, Helene McNulty, Catherine F Hughes, J J Strain, Mary Ward
Hypertension, a major risk factor for heart disease and stroke, is the world's leading cause of preventable, premature death. A common polymorphism (677C→T) in the gene encoding the folate metabolizing enzyme methylenetetrahydrofolate reductase (MTHFR) is associated with increased blood pressure, and there is accumulating evidence demonstrating that this phenotype can be modulated, specifically in individuals with the MTHFR 677TT genotype, by the B-vitamin riboflavin, an essential co-factor for MTHFR. The underlying mechanism that links this polymorphism, and the related gene-nutrient interaction, with hypertension is currently unknown...
November 11, 2016: Nutrients
https://www.readbyqxmd.com/read/27830979/dietary-and-supplemental-maternal-methyl-group-donor-intake-and-cord-blood-dna-methylation
#11
Sara Pauwels, Manosij Ghosh, Radu Corneliu Duca, Bram Bekaert, Kathleen Freson, Inge Huybrechts, Sabine Langie, Gudrun Koppen, Roland Devlieger, Lode Godderis
Maternal nutrition is critically involved in the development and health of the fetus. We evaluated maternal methyl-group donor intake through diet (methionine, betaine, choline, folate) and supplementation (folic acid) before and during pregnancy in relation to global DNA methylation and hydroxymethylation and gene specific (IGF2 DMR, DNMT1, LEP, RXRA) cord blood methylation. A total of 115 mother-infant pairs were enrolled in the MAternal Nutrition and Offspring's Epigenome (MANOE) study. The intake of methyl-group donors was assessed using a food-frequency questionnaire...
November 10, 2016: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/27829485/the-impact-of-doubling-dairy-or-plant-based-foods-on-consumption-of-nutrients-of-concern-and-proper-bone-health-for-adolescent-females
#12
Elieke Demmer, Christopher J Cifelli, Jenny A Houchins, Victor L Fulgoni
OBJECTIVE: To determine the effects of increasing plant-based foods v. dairy foods on energy and nutrients of concern in adolescent females via diet modelling exercises. DESIGN: Data from the National Health and Nutrition Examination Survey (NHANES) were used to compare nutrient intakes from usual diet with those from three dietary scenarios that increased current intakes by 100 % of the following: (i) plant-based foods; (ii) protein-rich plant-based foods; and (iii) milk, cheese and yoghurt...
November 10, 2016: Public Health Nutrition
https://www.readbyqxmd.com/read/27825397/micronutrient-intake-in-advanced-age-te-pu%C3%A4-waitanga-o-ng%C3%A4-tapuwae-kia-ora-tonu-life-and-living-in-advanced-age-a-cohort-study-in-new-zealand-lilacs-nz
#13
Carol Wham, Ruth Teh, Simon A Moyes, Anna Rolleston, Marama Muru-Lanning, Karen Hayman, Ngaire Kerse, Ashley Adamson
A high prevalence of undernutrition has previously been reported in indigenous Māori (49 %) and non-Māori (38 %) octogenarians and may be associated with risk of micronutrient deficiencies. We examined vitamin and mineral intakes and the contributing food sources among 216 Māori and 362 non-Māori participating in Life and Living to Advanced age a Cohort Study in New Zealand, using a repeat 24-h multiple-pass recall. More than half of the Māori and non-Māori participants had intakes below the estimated average requirement from food alone for Ca, Mg and Se...
November 9, 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27821202/food-composition-tables-in-resource-poor-settings-exploring-current-limitations-and-opportunities-with-a-focus-on-animal-source-foods-in-sub-saharan-africa
#14
Julia de Bruyn, Elaine Ferguson, Margaret Allman-Farinelli, Ian Darnton-Hill, Wende Maulaga, John Msuya, Robyn Alders
Animal-source foods (ASF) have the potential to enhance the nutritional adequacy of cereal-based diets in low- and middle-income countries, through the provision of high-quality protein and bioavailable micronutrients. The development of guidelines for including ASF in local diets requires an understanding of the nutrient content of available resources. This article reviews food composition tables (FCT) used in sub-Saharan Africa, examining the spectrum of ASF reported and exploring data sources for each reference...
November 8, 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27815234/a-brief-tool-to-assess-image-based-dietary-records-and-guide-nutrition-counselling-among-pregnant-women-an-evaluation
#15
Amy M Ashman, Clare E Collins, Leanne J Brown, Kym M Rae, Megan E Rollo
BACKGROUND: Dietitians ideally should provide personally tailored nutrition advice to pregnant women. Provision is hampered by a lack of appropriate tools for nutrition assessment and counselling in practice settings. Smartphone technology, through the use of image-based dietary records, can address limitations of traditional methods of recording dietary intake. Feedback on these records can then be provided by the dietitian via smartphone. Efficacy and validity of these methods requires examination...
November 4, 2016: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/27798335/a-prenatal-multiple-micronutrient-supplement-produces-higher-maternal-vitamin-b-12-concentrations-and-similar-folate-ferritin-and-zinc-concentrations-as-the-standard-60-mg-iron-plus-400-%C3%AE-g-folic-acid-supplement-in-rural-bangladeshi-women
#16
Shirin Ziaei, Anisur Rahman, Rubhana Raqib, Bo Lönnerdal, Eva-Charlotte Ekström
BACKGROUND: The effects of prenatal food and micronutrient supplementation on maternal micronutrient status are not well known. OBJECTIVE: We compared the efficacy and effectiveness of 3 different micronutrient supplements on maternal micronutrient status when combined with food supplementation. METHODS: In the MINIMat (Maternal and Infant Nutrition Intervention, Matlab) trial in Bangladesh, 4436 pregnant women were randomly assigned to daily intake of 3 types of micronutrient capsules: 30 mg Fe and 400 μg folic acid (Fe30F), 60 mg Fe and 400 μg folic acid (Fe60F), or multiple micronutrient supplements (MMNs) combined with early (week 9 of pregnancy) or usual (week 20 of pregnancy) food supplementation in a 2 by 3 factorial design...
October 19, 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27793182/homocysteine-metabolism-in-children-and-adolescents-with-epidermolysis-bullosa
#17
Rachele De Giuseppe, Greta Venturelli, Sophie Guez, Simona Salera, Claudia De Vita, Dario Consonni, Cinzia Dellanoce, Fabrizia Bamonti, Gabriella Chiarelli, Francesca Manzoni, Rita Maiavacca, Susanna Esposito
BACKGROUND: Epidermolysis bullosa (EB) belongs to a family of rare heterogeneous, genetic disorders characterized by blistering of the skin and mucous membranes in response to minor mechanical trauma. The involvement of the oral mucosa and oesophagus stenosis is suggested to be responsible for severe nutritional deficiencies, but few studies have till now considered this aspect. This observational study aimed to evaluate homocysteine status in children and adolescents with EB by assessing total plasma homocysteine (tHcy) and metabolically related vitamins (B6, B12, folate) concentrations...
October 29, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27783031/association-of-mthfr-slc19a1-genetic-polymorphism-serum-folate-vitamin-b12-and-hcy-status-with-cognitive-functions-in-chinese-adults
#18
Can Cai, Rong Xiao, Nicholas Van Halm-Lutterodt, Jie Zhen, Xiaochen Huang, Yao Xu, Shuying Chen, Linhong Yuan
BACKGROUND/AIM: Studies have indicated a relationship between either gene polymorphism or in vivo B vitamins' nutritional status with cognition in the elderly. However, the combined effects of MTHFR and SLC19A1gene polymorphism with serum folate and vitamin B12 levels on cognition in Chinese adult population remain unclear. METHODS: Demographic information of 426 Chinese adults aged from 55 to 90 were collected by a well designed self-administered questionnaire...
October 24, 2016: Nutrients
https://www.readbyqxmd.com/read/27765800/sex-specific-associations-between-one-carbon-metabolism-indices-and-posttranslational-histone-modifications-in-arsenic-exposed-bangladeshi-adults
#19
Caitlin G Howe, Xinhua Liu, Megan N Hall, Vesna Ilievski, Marie A Caudill, Olga Malysheva, Angela M Lomax-Luu, Faruque Parvez, Abu B Siddique, Hasan Shahriar, Mohammad N Uddin, Tariqul Islam, Joseph H Graziano, Max Costa, Mary V Gamble
BACKGROUND: Posttranslational histone modifications (PTHMs) are altered by arsenic, an environmental carcinogen. PTHMs are also influenced by nutritional methyl donors involved in one-carbon metabolism (OCM), which may protect against epigenetic dysregulation. METHODS: We measured global levels of three PTHMs, which are dysregulated in cancers (H3K36me2, H3K36me3, H3K79me2), in peripheral blood mononuclear cells (PBMCs) from 324 participants enrolled in the Folic Acid and Creatine Trial, a randomized trial in arsenic-exposed Bangladeshi adults...
October 20, 2016: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/27764973/predictors-of-cardiorespiratory-fitness-in-female-and-male-adults-with-different-body-mass-index-national-health-and-nutrition-examination-survey-1999-2004-dataset
#20
Liang Chen, Jian Kuang, Jian-Hao Pei, Hong-Mei Chen, Zhong Chen, Zhong-Wen Li, Hua-Zhang Yang, Xiao-Ying Fu, Long Wang, Zhi-Jiang Chen, Shui-Qing Lai, Shu-Ting Zhang
BACKGROUND: The aim of this study was to explore factors affecting cardiorespiratory fitness in males and females with different body mass index. METHODS: The National Health and Nutrition Examination Survey 1999-2004 data were used for this retrospective study. Estimated maximal oxygen uptake (VO2max) is surrogate for cardiorespiratory fitness (CRF). Univariate and multivariate linear regression analyses were performed to explore whether study variables were associated with estimated VO2max stratified by gender and BMI categories...
October 21, 2016: Annals of Medicine
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