Zeyu Tang, Suzhu Xie, Pengfei Min, Hang Li, Fanglin Zhao, Meng Liu, Weidong Jin, Longsheng Wang, Jianhao Zhao, Lijun Jia
The study aimed to explore the protective effects of Inonotus obliquus polysaccharide (IOP) on Neospora caninum (N. caninum) infection. Our data showed that the survival rate of the mice was the highest and the survival time was the longest when the IOP was 2 mg/10 g. In agreement with these observations, IOP alleviated the pathological damage in the various organs and tissues of the mice. Compared with that in the Neosporidium infection model group, the content of N. caninum in the heart, liver, spleen, lung, kidney and brain, determined through HE staining, was significantly lower...
February 1, 2024: International Journal of Biological Macromolecules