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https://www.readbyqxmd.com/read/28527030/intravitreal-erythropoietin-injection-in-late-stage-optic-neuropathy-a-safety-study-on-human
#1
Ugur Acar, Bekir Kucuk, Mehmet Koray Sevinc, Seckin Aykas, Mesut Erdurmus, Gungor Sobaci
AIM: To evaluate the whether intravitreal erythropoietin (EPO) administration has any beneficial or adverse effect in patients with late-stage optic neuropathy (ON) or not. METHODS: The study examined 16 eyes of 16 patients who had late-stage ON and ≥1/20 best-corrected visual acuity (BCVA) in their affected eye. There were nonarteritic ischemic ON in 10 (62.5%) eyes, traumatic ON in 4 (25.0%) eyes and methanol-induced ON in 2 (12.5%) eyes. Using pars plana approach, 2000 IU/0...
May 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28525666/complications-and-prostate-cancer-diagnosis-rate-of-trus-prostate-biopsies-using-16-and-18g-needles-by-clavien-scoring
#2
Serkan Ozcan, Mehmet Akif Diri, Murat Bagcioglu, Tolga Karakan, Arif Aydın
AIM: We aimed to compare the 18 and 16-Gauge (G) needles used in transrectal ultrasonography (TRUS)-guided needle biopsy for cancer detection rates and complications using the Clavien Scoring System. MATERIALS AND METHODS: The 80 patients who were included in the study were randomized and divided into two groups. Group 1 (n = 36) had a TRUS-guided prostate biopsy with an 18G needle and Group 2 had a 16G needle (n = 44). The hematuria, bleeding assessment, and infection events were evaluated on a daily basis...
May 16, 2017: Urologia
https://www.readbyqxmd.com/read/28524883/occurrence-rate-of-retinal-detachment-after-small-gauge-vitrectomy-for-idiopathic-epiretinal-membrane
#3
J Marie-Louise, E Philippakis, A Darugar, R Tadayoni, B Dupas
PurposeTo assess the occurrence rate of retinal detachment (RD) after small gauge vitrectomy for idiopathic epiretinal membrane (ERM).Patients and methodsRetrospective observational case series. The records of consecutive patients operated on for idiopathic ERM using small gauge pars plana vitrectomy between August 2012 and December 2014 with at least a 1-year follow-up were reviewed. All patients were contacted by phone to assess the occurrence of RD during the post-operative follow-up. The main outcome was the occurrence of RD...
May 19, 2017: Eye
https://www.readbyqxmd.com/read/28518071/nerve-sparing-mid-urethral-obstruction-nemo-in-female-small-rodents
#4
Martin Sidler, Karen J Aitken, Jia Xin Jiang, Darius J Bägli
Partial bladder outlet obstruction (pBOO) has a high prevalence, causes significant patient burden, and immense health care costs. The most common animal model to investigate bladder remodeling in pBOO are female rodents undergoing partial obstruction at the proximal urethra. Variability in the degree of obstruction and animal mortality are major concerns with proximal obstruction. Furthermore, dissecting around the proximal urethra and bladder neck jeopardizes bladder innervation. We developed a nerve-sparing mid-urethral obstruction (NeMO) model for pBOO avoiding the disadvantages of the traditional model...
April 25, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28513500/rescue-vitrectomy-with-blocked-artery-massage-and-bloodletting-for-branch-retinal-artery-occlusion
#5
Chun-Ju Lin, Cheng-Wen Su, Huan-Sheng Chen, Wen-Lu Chen, Jane-Ming Lin, Yi-Yu Tsai
A 61-year-old male suffered from sudden blurred vision and superior visual field defect oculus dexter. His vision was counting fingers at 20 cm. Fundoscopy demonstrated inferior pale retina and a large embolus located at the proximal inferior retinal artery. Branch retinal artery occlusion (BRAO) was diagnosed. Initial paracentesis, topical brimonidine tartrate, oral pentoxifylline, and hyperbaric oxygen therapy were performed but showed limited improvement. Hence, he received 25-gauge vitrectomy, artificial posterior vitreous detachment, blocked retinal artery massage, and bloodletting 5 days after onset...
April 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28475790/prevalence-of-healthcare-associated-infections-and-antimicrobial-use-among-adult-inpatients-in-singapore-acute-care-hospitals-results-from-the-first-national-point-prevalence-survey
#6
Yiying Cai, Indumathi Venkatachalam, Nancy W Tee, Thean Yen Tan, Asok Kurup, Sin Yew Wong, Chian Yong Low, Yang Wang, Winnie Lee, Yi Xin Liew, Brenda Ang, David C Lye, Angela Chow, Moi Lin Ling, Helen M Oh, Cassandra A Cuvin, Say Tat Ooi, Surinder K Pada, Chong Hee Lim, Jack Wei Chieh Tan, Kean Lee Chew, Van Hai Nguyen, Dale A Fisher, Herman Goossens, Andrea L Kwa, Paul A Tambyah, Li Yang Hsu, Kalisvar Marimuthu
Background: We conducted a national point prevalence survey (PPS) to determine the prevalence of healthcare-associated infections (HAIs) and antimicrobial use (AMU) in Singapore acute-care hospitals. Methods: Trained personnel collected HAI, AMU, and baseline hospital- and patient-level data of adult inpatients from 13 private and public acute-care hospitals between July 2015 and February 2016, using the PPS methodology developed by the European Centre for Disease Prevention and Control...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28461738/the-effect-of-vitreomacular-and-cataract-surgery-on-oxygen-saturation-in-retinal-vessels
#7
Yuki Nakano, Koichiro Manabe, Rie Osaka, Yukari Takasago, Aoi Ono, Mamoru Kobayashi, Tomoyoshi Fujita, Chieko Shiragami, Kazuyuki Hirooka, Akitaka Tsujikawa
PURPOSE: To evaluate the effects of vitreomacular and cataract surgery on retinal oximetry in vitreomacular disease. PATIENTS AND METHODS: Thirty-eight eyes with epiretinal membrane (ERM) and 15 with idiopathic macular hole (MH) underwent 25 gauge pars plana vitrectomy combined with cataract surgery and intraocular lens implantation. Retinal oximetry was performed using the Oxymap T1 before, 1 month, and 6 months after surgery. Oxymap T1 simultaneously captures monochrome images of the fundus at two different wavelengths of light...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28461017/vitrectomy-and-vitrector-port-needle-biopsy-of-choroidal-melanoma-for-gene-expression-profile-testing-immediately-before-brachytherapy
#8
Deepthi M Reddy, Lauren B Mason, John O Mason, Jason N Crosson, Jacob J Yunker
PURPOSE: Transvitreal and transscleral needle biopsy can result in complications including vitreous hemorrhage and retinal detachment. This study evaluated a technique using 25-gauge vitrectomy as an adjunct to needle biopsy immediately before brachytherapy to minimize these complications and preserve good visual acuity. DESIGN: Retrospective, observational case series. PARTICIPANTS: Fifty-seven consecutive eyes of 57 patients with treatment-naïve medium choroidal melanomas without extraocular extension from July 2012 through September 2015...
April 28, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28458513/perioperative-changes-of-the-intraocular-pressure-during-the-treatment-of-epiretinal-membrane-by-using-25-or-27-gauge-sutureless-vitrectomy-without-gas-tamponade
#9
Hirotsugu Takashina, Akira Watanabe, Hiroshi Tsuneoka
PURPOSE: The purpose of this study was to compare perioperative intraocular pressures (IOPs) in 25- or 27-gauge microincision vitrectomy surgery (MIVS) and to evaluate the stability of postoperative sclerotomy closure. MATERIALS AND METHODS: This is a retrospective review of 147 eyes treated for epiretinal membrane by using 25- or 27-gauge MIVS as the initial vitrectomy (25-gauge phacovitrectomy [25-P group]: 73 eyes, 25-gauge vitrectomy alone [25-A group]: 15 eyes, 27-gauge phacovitrectomy [27-P group]: 47 eyes, and 27-gauge vitrectomy alone [27-A group]: 12 eyes)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28457847/role-of-mechanical-curettage-with-and-without-adjunct-antimicrobial-photodynamic-therapy-in-the-treatment-of-peri-implant-mucositis-in-cigarette-smokers-a-randomized-controlled-clinical-trial
#10
Fawad Javed, Munerah Saleh BinShabaib, Shatha Subhi Alharthi, Talat Qadri
OBJECTIVE: The aim of the present 12-weeks follow-up randomized clinical trial was to investigate the outcome of mechanical curettage (MC) with or without adjunct antimicrobial photodynamic therapy (aPDT) in the treatment of peri-implant mucositis in cigarette smokers. METHODS: Therapeutically, subjects with peri-implant mucositis were divided into 2 groups: (a) Group-A: MC+aPDT; and (b) Group-B: MC alone (control group). In both groups, peri-implant plaque index (PI), bleeding on probing (BOP) and probing pocket depth (PPD) were gauged at baseline and after 12-weeks follow-up...
April 27, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28457613/flanged-intrascleral-intraocular-lens-fixation-with-double-needle-technique
#11
Shin Yamane, Shimpei Sato, Maiko Maruyama-Inoue, Kazuaki Kadonosono
PURPOSE: To report the clinical outcomes of a new technique for transconjunctival intrascleral fixation of an intraocular lens (IOL). DESIGN: Prospective, noncomparative, interventional case series. PARTICIPANTS: One hundred eyes of 97 consecutive patients with aphakia, dislocated IOL, or subluxated crystalline lens who underwent posterior chamber sutureless implantation of an IOL were studied. METHODS: Two angled incisions parallel to the limbus were made by 30-gauge thin-wall needles...
April 27, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28448664/assessment-of-lower-doses-of-intravitreous-bevacizumab-for-retinopathy-of-prematurity-a-phase-1-dosing-study
#12
David K Wallace, Raymond T Kraker, Sharon F Freedman, Eric R Crouch, Amy K Hutchinson, Amit R Bhatt, David L Rogers, Michael B Yang, Kathryn M Haider, Deborah K VanderVeen, R Michael Siatkowski, Trevano W Dean, Roy W Beck, Michael X Repka, Lois E Smith, William V Good, Mary Elizabeth Hartnett, Lingkun Kong, Jonathan M Holmes
Importance: Intravitreous bevacizumab (0.25 to 0.625 mg) is increasingly used to treat type 1 retinopathy of prematurity (ROP), but there remain concerns about systemic toxicity. A much lower dose may be effective while reducing systemic risk. Objective: To find a dose of intravitreous bevacizumab that was lower than previously used for severe ROP, was effective in this study, and could be tested in future larger studies. Design, Setting, and Participants: Between May 2015 and September 2016, 61 premature infants with type 1 ROP in 1 or both eyes were enrolled in a masked, multicenter, phase 1 dose de-escalation study...
April 27, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28444950/optical-coherence-tomography-evaluation-of-patients-with-macula-off-retinal-detachment-after-different-postoperative-posturing-a-randomized-pilot-study
#13
Enrico Peiretti, Francesco Nasini, Elisa Buschini, Giulia Caminiti, Sarit Y Lesnik Oberstein, Alissa Willig, Heico M Bijl, Marco Mura
PURPOSE: To assess the presence of outer and inner retinal folds (RFs) and drop-out of the ellipsoid zone (EZ) occurring after surgical repair of macula-off rhegmatogenous retinal detachment (RRD) with different postoperative posture and preoperative use of adjuvant perfluorocarbon liquid (PFCO). METHODS: In this prospective study, 56 eyes of 56 consecutive patients affected by RRD were subjected to 23- or 25-gauge pars plana vitrectomy (PPV). The patients were randomized in four groups (14 prone 5 hr without PFCO, 14 supine 5 hr without PFCO, 14 prone 5 hr with PFCO and 14 supine 5 hr with PFCO) and followed up with spectral domain optical coherence tomography (SD-OCT)...
April 26, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28420906/comparison-of-ultrasound-and-ultrasound-plus-nerve-stimulator-guidance-axillary-plexus-block
#14
Gokhan Demirelli, Semih Baskan, Isil Karabeyoglu, Ismail Aytac, Dilsen Hatice Ornek, Alper Erdogmus, Mustafa Baydar
OBJECTIVE: To evaluate the characteristics of axillary plexus blockade applied using ultrasound only and using ultrasound together with nerve stimulator in patients undergoing planned forearm, wrist or hand surgery. METHODS: This randomised, prospective, double-blinded, single-centre study was conducted at Ankara Numune Training and Research Hospital, Ankara, Turkey, from November 2014 to August 2015, and comprised patients undergoing forearm, wrist or hand surgery...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28418609/real-time-measurement-of-needle-forces-and-acute-pressure-changes-during-intravitreal-injections
#15
Logan Christensen, Ashlee Cerda, Jeffrey L Olson
BACKGROUND: The purpose of this study was to use a physiological pressure transducer to measure real-time, continuous pressure changes in an ex-vivo study model of porcine eyes to record the amount of force needed for scleral penetration and to measure acute IOP rise during intravitreal injections. METHODS: A pressure transducer was inserted into the anterior chamber of 30 fresh porcine eyes and intraocular pressure was measured two seconds prior to intravitreal injection until two seconds after...
April 18, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28412068/vitreous-amyloidosis-ocular-systemic-and-genetic-insights
#16
Pradeep Venkatesh, Harathy Selvan, Sundararajan Baskar Singh, Divya Gupta, Seema Kashyap, Shreyas Temkar, Varun Gogia, Koushik Tripathy, Rohan Chawla, Rajpal Vohra
PURPOSE: To report the unique clinical and surgical characteristics encountered in eyes with vitreous amyloidosis. Systemic evaluation and visual outcome after vitrectomy are discussed. A novel mutation in the transthyretin gene (TTR) in Indian patients with familial amyloid polyneuropathy (FAP) is described. DESIGN: Retrospective, observational study. PARTICIPANTS: Ten eyes of 5 patients from 2 pedigrees with a diagnosis of vitreous amyloidosis...
April 12, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28410708/twenty-nine-gauge-dual-chandelier-retroillumination-for-the-non-open-sky-continuous-curvilinear-capsulorhexis-in-the-penetrating-keratoplasty-triple-procedure
#17
Shunji Yokokura, Takehiro Hariya, Wataru Kobayashi, Yasuhiko Meguro, Kohji Nishida, Toru Nakazawa
We describe a technique for the penetrating keratoplasty (PKP) triple procedure that uses 29-gauge dual-chandelier illumination during creation of a non-open-sky continuous curvilinear capsulorhexis (CCC). The chandeliers are inserted through the pars plana into the vitreous cavity through the bulbar conjunctiva at the 3 o'clock and 9 o'clock positions. We compared this approach with that of a core vitrectomy, in which a single 25-gauge port is inserted into the vitreous cavity transconjunctivally through the upper temporal pars plana...
March 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28396814/the-histopathological-finding-of-the-surgically-extracted-atypical-dome-shaped-choroidal-osteoma
#18
Hirona Bessho, Hisanori Imai, Atsushi Azumi
Purpose. To report a case of atypical dome-shaped choroidal osteoma, which was diagnosed by histopathological finding of surgically extracted tumor. Case Report. A 35-year-old woman presented with visual field abnormality in the left eye (OS). Her best-corrected visual acuity with Landolt ring chart was 1.0 OS. The funduscopic examination revealed a yellowish dome-shaped choroidal tumor located in the temporal side of the macula with exudative retinal detachment. 25-gauge pars plana vitrectomy and the extraction of the tumor were performed for the definitive diagnosis...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/28390161/sonographic-visualization-of-the-posterior-cutaneous-nerve-of-the-forearm-technique-and-validation-using-perineural-injections-in-a-cadaveric-model
#19
Eugene Maida, Mary M Chiavaras, Elena J Jelsing, Shawn W O'Driscoll, Wojciech Pawlina, Jay Smith
OBJECTIVES: To determine the ability to sonographically identify the posterior cutaneous nerve of the forearm (PCNF) and its distal epicondylar branches using sonographically guided perineural injections in an unembalmed cadaveric model. METHODS: A single experienced operator used a 12-3-MHz linear array transducer to identify the PCNF and its distal epicondylar region branches in 10 unembalmed cadaveric specimens (6 right and 4 left) obtained from 10 donors. Sonographically guided perineural PCNF injections were then completed with a 22-gauge, 38-mm stainless steel needle to deliver 0...
April 8, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28389702/cooperative-robot-assistant-for-vitreoretinal-microsurgery-development-of-the-rvrms-and-feasibility-studies-in-an-animal-model
#20
Yi-Qi Chen, Ji-Wei Tao, Ling-Ya Su, Liang Li, Shi-Xin Zhao, Yang Yang, Li-Jun Shen
PURPOSE: The purpose of the study was to describe the development of a robotic aided surgical system named RVRMS (robotic vitreous retinal microsurgery system) and to evaluate the capability for using it to perform vitreoretinal surgery. METHODS: The RVRMS was designed and built to include the key components of two independent arms. End-effectors of each arm fix various surgical instruments and perform intraocular manipulation. To evaluate properly the RVRMS, robot-assisted 23-gauge surgical tasks including endolaser for retinal photocoagulation, pars plana vitrectomy (PPV), retinal foreign body removal and retinal vascular cannulation were performed in two different sizes of an animal model...
April 8, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
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