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Traumatic brain injury review

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https://www.readbyqxmd.com/read/28433414/diffusion-tensor-imaging-findings-and-cognitive-function-following-hospitalised-mixed-mechanism-mild-traumatic-brain-injury-a-systematic-review-and-meta-analysis
#1
REVIEW
Lucy Oehr, Jacqueline Anderson
OBJECTIVE: To undertake a systematic review and meta-analysis of the relationship between microstructural damage and cognitive function following hospitalised mixed-mechanism (HMM) mild traumatic brain injury (mTBI). DATA SOURCES: PsycInfo, Embase, and Medline were used to find relevant empirical papers published between January 2002 to January 2016. STUDY SELECTION: Studies that examined the specific relationship between diffusion tensor imaging (DTI) and cognitive test performance were included...
April 19, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28430672/lamotrigine-uses-in-psychiatric-practice-beyond-bipolar-prophylaxis-a-hope-or-hype
#2
Ahmed Naguy, Najah Al-Enezi
BACKGROUND: Lamotrigine (LAM), an antiepileptic, with panoply of indications and uses in neurology, is FDA approved, in psychiatry, for bipolar prophylaxis. Apart from this indication, trend of its use in psychiatry is on the rise addressing a multitude of disorders. STUDY QUESTION: LAM remains one of only few psychotropic drugs with antiglutamate activity. This might render LAM a potential therapeutic option in treatment-resistant major psychiatric disorders. We reviewed LAM pharmacology and its diverse indications while examining the extant evidence...
April 19, 2017: American Journal of Therapeutics
https://www.readbyqxmd.com/read/28426839/medical-history-in-the-hellenic-journal-of-nuclear-medicine
#3
EDITORIAL
Andreas Otte, Byeong Cheol Ahn
The Hellenic Journal of Nuclear Medicine is about to celebrate its 20th anniversary end of 2017. On board of the editorial team since 2003, this journal has influenced me like a good friend over the many past years. From time to time, the journal has published interesting and valuable historical notes. They show that nuclear medicine has a history and that medicine is its basis. They also teach us today, and some of the ancient perspectives and approaches are still valid. The reader of HJNM may be interested in these historical contributions, as they are timeless...
January 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28425776/development-of-the-aboriginal-communication-assessment-after-brain-injury-acaabi-a-screening-tool-for-identifying-acquired-communication-disorders-in-aboriginal-australians
#4
Elizabeth M Armstrong, Natalie Ciccone, Deborah Hersh, Judith Katzenellebogen, Juli Coffin, Sandra Thompson, Leon Flicker, Colleen Hayward, Deborah Woods, Meaghan McAllister
PURPOSE: Acquired communication disorders (ACD), following stroke and traumatic brain injury, may not be correctly identified in Aboriginal Australians due to a lack of linguistically and culturally appropriate assessment tools. Within this paper we explore key issues that were considered in the development of the Aboriginal Communication Assessment After Brain Injury (ACAABI) - a screening tool designed to assess the presence of ACD in Aboriginal populations. METHOD: A literature review and consultation with key stakeholders were undertaken to explore directions needed to develop a new tool, based on existing tools and recommendations for future developments...
February 21, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28425334/remifentanil-for-sedation-of-children-with-traumatic-brain-injury
#5
James L Hungerford, Nicole O'Brien, Melissa Moore-Clingenpeel, Eric A Sribnick, Cheryl Sargel, Mark Hall, Jeffrey R Leonard, Joseph D Tobias
OBJECTIVE: To determine whether remifentanil would provide adequate sedation while allowing frequent and reproducible neurologic assessments in children admitted to the pediatric intensive care unit (PICU) with traumatic brain injury (TBI) during mechanical ventilation. DESIGN: Retrospective review. SETTING: Tertiary care PICU. PATIENTS: Thirty-eight patients over a 30-month period. MEASUREMENTS AND MAIN RESULTS: Median age was 9 years (interquartile range [IQR] 2...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28422897/outcomes-associated-with-blast-versus-nonblast-related-traumatic-brain-injury-in-us-military-service-members-and-veterans-a-systematic-review
#6
Nancy Greer, Nina Sayer, Eva Koeller, Tina Velasquez, Timothy J Wilt
OBJECTIVES: To systematically review the literature on comparative clinical and functional outcomes following blast-related versus nonblast-related traumatic brain injury (TBI) among US service members and Veterans. DESIGN: MEDLINE search (January 2001 to June 2016) supplemented with hand search of reference lists and input from peer reviewers. RESULTS: Thirty-one studies (in 33 articles) reported on health outcomes; only 2 were rated low risk of bias...
April 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28422643/occupational-therapy-interventions-for-adults-with-traumatic-brain-injury
#7
Steven Wheeler, Amanda Acord-Vira, Marian Arbesman, Deborah Lieberman
This Evidence Connection describes a case report of an adult with traumatic brain injury (TBI), applying the evidence for intervention from the systematic reviews on TBI that were conducted in conjunction with the American Occupational Therapy Association's (AOTA's) Evidence-Based Practice Project. The occupational therapy assessment and treatment processes for hospital, home, and community settings are described. Evidence Connection articles provide a clinical application of systematic reviews developed in conjunction with AOTA's Evidence-Based Practice Project...
May 2017: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/28421863/a-meta-analysis-of-task-related-influences-in-prospective-memory-in-traumatic-brain-injury
#8
Daniela Wong Gonzalez, Lori Buchanan
Prospective memory is the ability to remember to do something in the future and it is essential to every-day functional independence. Traumatic brain injury is associated with frequent and persistent prospective memory deficits. This study presents a review and meta-analysis investigating the effects of task parameters on prospective memory performance of individuals with TBI. Individual studies using continuous behavioural measures of prospective memory with a sample of adults with TBI and matched controls were included...
April 19, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/28417449/citicoline-pharmacological-and-clinical-review-2016-update
#9
REVIEW
J J Secades
This review is based on the previous one published in 2010 -Secades JJ. Citicoline: pharmacological and clinical review, 2010 update. Rev Neurol 2011; 52 (Suppl 2): S1-62-, incorporating 183 new references, having all the information available to facilitate the access to the information in one document. This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications...
December 23, 2016: Revista de Neurologia
https://www.readbyqxmd.com/read/28409764/using-the-narratives-of-ontarians-with-a-work-related-traumatic-brain-injury-to-inform-injury-prevention-a-mixed-methods-approach
#10
Vanessa Amodio, Heather Bruch, Tatyana Mollayeva, Angela Colantonio
BACKGROUND: Work-related traumatic brain injury (wrTBI) is the most significant occupational injury associated with death and disability. Few studies have investigated injury text narratives to inform prevention strategies. OBJECTIVE: To identify factors leading to wrTBI in male and female workers utilizing the Person-Environment-Occupation (P-E-O) framework. METHODS: A retrospective chart review of the medical records of 98 consecutive Ontario workers with a diagnosed wrTBI was performed...
April 12, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28408366/acute-brain-trauma-lung-injury-and-pneumonia-more-than-just-altered-mental-status-and-decreased-airway-protection
#11
Parker J Hu, Jean-Francois Pittet, Jeffrey D Kerby, Patrick L Bosarge, Brant M Wagener
Traumatic brain injury (TBI) is a major cause of mortality and morbidity worldwide. Even when patients survive the initial insult, there is significant morbidity and mortality secondary to subsequent pulmonary edema, acute lung injury and nosocomial pneumonia. While the relationship between TBI and secondary pulmonary complications is recognized, little is known about the mechanistic interplay of the two phenomena. Changes in mental status secondary to acute brain injury certainly impair airway- and lung-protective mechanisms...
April 13, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28407334/time-to-cranial-computerised-tomography-for-acute-traumatic-brain-injury-in-paediatric-patients-effect-of-the-shorter-stays-in-emergency-departments-target-in-new-zealand
#12
Peter G Jones, Bridget Kool, Stuart Dalziel, Michael Shepherd, James Le Fevre, Alana Harper, Susan Wells, Joanna Stewart, Elana Curtis, Papaarangi Reid, Shanthi Ameratunga
AIM: Timely access to computerised tomography (CT) for acute traumatic brain injuries (TBIs) facilitates rapid diagnosis and surgical intervention. In 2009, New Zealand introduced a mandatory target for emergency department (ED) stay such that 95% of patients should leave ED within 6 h of arrival. This study investigated whether this target influenced the timeliness of cranial CT scanning in children who presented to ED with acute TBI. METHODS: We retrospectively reviewed a random sample of charts of children <15 years with acute TBI from 2006 to 2012...
April 13, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28399158/mild-traumatic-brain-injury-mtbi-and-chronic-cognitive-impairment-a-scoping-review
#13
Kerry McInnes, Christopher L Friesen, Diane E MacKenzie, David A Westwood, Shaun G Boe
Mild traumatic brain injury (mTBI), or concussion, is the most common type of traumatic brain injury. With mTBI comes symptoms that include headaches, fatigue, depression, anxiety and irritability, as well as impaired cognitive function. Symptom resolution is thought to occur within 3 months post-injury, with the exception of a small percentage of individuals who are said to experience persistent post-concussion syndrome. The number of individuals who experience persistent symptoms appears to be low despite clear evidence of longer-term pathophysiological changes resulting from mTBI...
2017: PloS One
https://www.readbyqxmd.com/read/28396091/targeting-mitochondrial-dysfunction-in-cns-injury-using-methylene-blue-still-a-magic-bullet
#14
Hemendra J Vekaria, Lora Talley Watts, Ai-Ling Lin, Patrick G Sullivan
Complex, multi-factorial secondary injury cascades are initiated following traumatic brain injury, which makes this a difficult disease to treat. The secondary injury cascades following the primary mechanical tissue damage, are likely where effective therapeutic interventions may be targeted. One promising therapeutic target following brain injury are mitochondria. Mitochondria are complex organelles found within the cell, which act as powerhouses within all cells by supplying ATP. These organelles are also necessary for calcium cycling, redox signaling and play a major role in the initiation of cell death pathways...
April 7, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28390522/research-frontiers-in-traumatic-brain-injury-defining-the-injury
#15
REVIEW
Andrew J Gardner, Shirley L Shih, Elizabeth V Adamov, Ross D Zafonte
With the continued advancement in technology, such as increasingly sophisticated neuroimaging parameters, and the ongoing development of various scientific fields, like serum and blood biomarkers, genetics, and physiology, traumatic brain injury (TBI) research is a dynamic field of study. TBI remains a significant public health concern and research has continued to grow exponentially over the past decade. This review provides an overview of the frontiers of TBI research, from sports concussion to severe TBI, from acute and subacute injury to long-term/chronic outcomes, from assessment and management to prognosis, specifically examining recent neuroimaging, biomarkers, genetics, and physiologic studies...
May 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/28390519/integrative-medicine-in-traumatic-brain-injury
#16
REVIEW
David F Drake, Anne M Hudak, William Robbins
Complementary and alternative medicine (CAM) is a group of diverse medical and health care systems, practices, and products that are not presently considered to be a part of conventional medicine. Integrative medicine combines treatment with conventional medical practices and elements of CAM in which there is strong evidence in efficacy and safety. Although there is growing interest in the integrative medical approach in treating the patient population with traumatic brain injury, there is a paucity in high-quality clinical trials supporting its use...
May 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/28390516/unique-aspects-of-traumatic-brain-injury-in-military-and-veteran-populations
#17
REVIEW
Patrick Armistead-Jehle, Jason R Soble, Douglas B Cooper, Heather G Belanger
Traumatic brain injury (TBI), in particular mild TBI (mTBI), is a relatively common injury experienced by service members across both deployed and nondeployed environments. Although many of the principles and practices used by civilian health care providers for identifying and treating this injury apply to military settings, there are unique factors that impact mTBI-related care in service members and Veterans. This article reviews several of these factors, including the epidemiology of TBI in the military/Veteran population, the influence of military culture on this condition, and identification and treatment of mTBI in the war zone...
May 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/28390509/pathophysiology-of-traumatic-brain-injury
#18
REVIEW
Kirsty J Dixon
Traumatic brain injury (TBI) has become the signature injury of the military conflict in Iraq and Afghanistan and also has a high rate of occurrence in civilian populations in the United States. Although the effects of a moderate to severe brain injury have been investigated for decades, the chronic effects of single and repetitive mild TBI are just beginning to be investigated. Data suggest that the different types and severities of TBI have unique long-term outcomes and thus may represent different types of diseases...
May 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/28387644/medical-necessity-of-routine-admission-of-children-with-mild-traumatic-brain-injury-to-the-intensive-care-unit
#19
Jared D Ament, Krista N Greenan, Patrick Tertulien, Joseph M Galante, Daniel K Nishijima, Marike Zwienenberg
OBJECTIVE Approximately 475,000 children are treated for traumatic brain injury (TBI) in the US each year; most are classified as mild TBI (Glasgow Coma Scale [GCS] Score 13-15). Patients with positive findings on head CT, defined as either intracranial hemorrhage or skull fracture, regardless of severity, are often transferred to tertiary care centers for intensive care unit (ICU) monitoring. This practice creates a significant burden on the health care system. The purpose of this investigation was to derive a clinical decision rule (CDR) to determine which children can safely avoid ICU care...
April 7, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28387560/clinical-evaluation-of-the-concussed-athlete-a-view-from-the-sideline
#20
Margot Putukian
CONTEXT: The sideline assessment of concussion is challenging, given its variable presentations, the limited sensitivity and specificity of sideline assessment tools, and how the presentation of the injury evolves over time. In addition, the diagnostic process, as well as the tools used to assess and manage concussion, continue to progress as research and what we know about concussion advance. This paper focuses on the initial assessment on the sideline by reviewing the concussion-evaluation literature, drawing from clinical experience to emphasize a standardized approach, and underscoring the importance of both familiarity with the athlete and clinical judgment...
March 2017: Journal of Athletic Training
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