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https://www.readbyqxmd.com/read/27918269/prevention-of-hospital-acquired-bloodstream-infections-through-chlorhexidine-gluconate-impregnated-washcloth-bathing-in-intensive-care-units-a-systematic-review-and-meta-analysis-of-randomised-crossover-trials
#1
Elsa Afonso, Koen Blot, Stijn Blot
We assessed the impact of 2% daily patient bathing with chlorhexidine gluconate (CHG) washcloths on the incidence of hospital-acquired (HA) and central line-associated (CLA) bloodstream infections (BSI) in intensive care units (ICUs). We searched randomised studies in Medline, EMBASE, Cochrane Library (CENTRAL) and Web of Science databases up to April 2015. Primary outcomes were total HABSI, central line, and non-central line-associated BSI rates per patient-days. Secondary outcomes included Gram-negative and Gram-positive BSI rates and adverse events...
November 17, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27876075/chlorhexidine-bathing-and-health-care-associated-infections-among-adult-intensive-care-patients-a-systematic-review-and-meta-analysis
#2
Steven A Frost, Mari-Cris Alogso, Lauren Metcalfe, Joan M Lynch, Leanne Hunt, Ritesh Sanghavi, Evan Alexandrou, Kenneth M Hillman
BACKGROUND: Health care-associated infections (HAI) have been shown to increase length of stay, the cost of care, and rates of hospital deaths (Kaye and Marchaim, J Am Geriatr Soc 62(2):306-11, 2014; Roberts and Scott, Med Care 48(11):1026-35, 2010; Warren and Quadir, Crit Care Med 34(8):2084-9, 2006; Zimlichman and Henderson, JAMA Intern Med 173(22):2039-46, 2013). Importantly, infections acquired during a hospital stay have been shown to be preventable (Loveday and Wilson, J Hosp Infect 86:S1-70, 2014)...
November 23, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27861350/chlorhexidine-bathing-for-the-prevention-of-colonization-and-infection-with-multidrug-resistant-microorganisms-in-a-hematopoietic-stem-cell-transplantation-unit-over-a-9-year-period-impact-on-chlorhexidine-susceptibility
#3
Elisa Teixeira Mendes, Otavio T Ranzani, Ana Paula Marchi, Mariama Tomaz da Silva, José Ulysses Amigo Filho, Tânia Alves, Thais Guimarães, Anna S Levin, Silvia Figueiredo Costa
Health care associated infections (HAIs) are currently among the major challenges to the care of hematopoietic stem cell transplantation (HSCT) patients. The objective of the present study was to evaluate the impact of 2% chlorhexidine (CHG) bathing on the incidence of colonization and infection with vancomycin-resistant Enterococcus (VRE), multidrug-resistant (MDR) gram-negative pathogens, and to evaluate their CHG minimum inhibitory concentration (MIC) after the intervention.A quasi-experimental study with duration of 9 years was conducted...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27676109/bathing-and-beyond-current-bathing-controversies-for-newborn-infants
#4
Carolyn Lund
BACKGROUND: Bathing the newborn infant is controversial, ranging from how and when to give the newborn their first bath, whether to bathe newborns at all in the initial days of life, and how to approach bathing the hospitalized premature and full-term infant in the neonatal intensive care unit (NICU). PURPOSE: To review relevant literature about bathing newborn infants, as well as examine the controversies about bathing NICU patients including the use of daily chlorhexidine gluconate (CHG) baths...
October 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/27457254/elimination-of-routine-contact-precautions-for-endemic-methicillin-resistant-staphylococcus-aureus-and-vancomycin-resistant-enterococcus-a-retrospective-quasi-experimental-study
#5
Elise M Martin, Dana Russell, Zachary Rubin, Romney Humphries, Tristan R Grogan, David Elashoff, Daniel Z Uslan
OBJECTIVE To evaluate the impact of discontinuation of contact precautions (CP) for methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) and expansion of chlorhexidine gluconate (CHG) use on the health system. DESIGN Retrospective, nonrandomized, observational, quasi-experimental study. SETTING Two California hospitals. PARTICIPANTS Inpatients. METHODS We compared hospital-wide laboratory-identified clinical culture rates (as a marker of healthcare-associated infections) 1 year before and after routine CP for endemic MRSA and VRE were discontinued and CHG bathing was expanded to all units...
November 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27392413/chlorhexidine-patient-bathing-and-infection-prevention
#6
REVIEW
Salma Abbas, Sangeeta Sastry
Healthcare-associated infections (HAIs) are an important cause of morbidity and mortality in the USA. They are associated with a substantial increase in health care costs each year. Fortunately, many HAIs are preventable, and their eradication is a national priority. Chlorhexidine (CHG) bathing has been used as an infection prevention measure, either alone or bundled with other interventions, with mostly beneficial results. The recent surge in its use as an agent of choice for skin antisepsis has lead to concerns over emerging resistance among microorganisms...
August 2016: Current Infectious Disease Reports
https://www.readbyqxmd.com/read/27306279/chlorhexidine-bathing-effects-on-health-care-associated-infections
#7
Janette Denny, Cindy L Munro
BACKGROUND: Health-care-associated infections (HAIs), infections that patients contract during the course of their hospitalization, are receiving a growing amount of attention. Heavy skin bacterial colonization aids in the transmission and development of HAIs. Nurses frequently use bathing with chlorhexidine gluconate (CHG) to reduce patients' cutaneous microbial burden. This intervention has been shown to have promising but mixed results in the prevention of HAIs. PURPOSE: This article reviews the literature for evidence on the impact of CHG bathing on HAIs...
June 15, 2016: Biological Research for Nursing
https://www.readbyqxmd.com/read/27048258/the-efficacy-of-daily-chlorhexidine-bathing-for-preventing-healthcare-associated-infections-in-adult-intensive-care-units
#8
Hua-Ping Huang, Bin Chen, Hai-Yan Wang, Me He
Background/Aims: Healthcare-associated infections (HAIs) in critically ill patients with prolonged length of hospital stay and increased medical costs. The aim of this study is to assess whether daily chlorhexidine gluconate (CHG) bathing will significantly reduce the rates of HAIs in adult intensive care units (ICUs). Methods: PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials were systematically searched until December 31, 2014 to identify relevant studies...
April 6, 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/26861417/a-multicenter-pragmatic-interrupted-time-series-analysis-of-chlorhexidine-gluconate-bathing-in-community-hospital-intensive-care-units
#9
Kristen V Dicks, Eric Lofgren, Sarah S Lewis, Rebekah W Moehring, Daniel J Sexton, Deverick J Anderson
OBJECTIVE To determine whether daily chlorhexidine gluconate (CHG) bathing of intensive care unit (ICU) patients leads to a decrease in hospital-acquired infections (HAIs), particularly infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). DESIGN Interrupted time series analysis. SETTING The study included 33 community hospitals participating in the Duke Infection Control Outreach Network from January 2008 through December 2013. PARTICIPANTS All ICU patients at study hospitals during the study period...
July 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/26836601/the-effect-of-chlorhexidine-bathing-on-rates-of-nosocomial-infections-among-the-critically-ill-population-an-analysis-of-current-clinical-research-and-recommendations-for-practice
#10
Kimberly Raines, Kelsey Rosen
BACKGROUND: This literature review examined the current research of evidence-based standards to evaluate the effectiveness of daily bathing with 2% chlorhexidine gluconate (CHG; manufactured by Sage Products Inc) compared with traditional non-antimicrobial bathing on reducing the incidence of nosocomial infections in the critically ill population. OBJECTIVE/AIM: The objective of this article is 3-fold: first, to provide a background on the increased susceptibility to pathogens that have become endemic in many intensive care units; second, to challenge health care providers to question current practice and consider additional ways to ensure safety and better outcomes in the critically ill population; and third, to provide health care providers with clinical evidence to avoid infection control failures...
March 2016: Dimensions of Critical Care Nursing: DCCN
https://www.readbyqxmd.com/read/26828094/prevalence-of-qaca-b-genes-and-mupirocin-resistance-among-methicillin-resistant-staphylococcus-aureus-mrsa-isolates-in-the-setting-of-chlorhexidine-bathing-without-mupirocin
#11
David K Warren, Martin Prager, Satish Munigala, Meghan A Wallace, Colleen R Kennedy, Kerry M Bommarito, John E Mazuski, Carey-Ann D Burnham
OBJECTIVE: We aimed to determine the frequency of qacA/B chlorhexidine tolerance genes and high-level mupirocin resistance among MRSA isolates before and after the introduction of a chlorhexidine (CHG) daily bathing intervention in a surgical intensive care unit (SICU). DESIGN: Retrospective cohort study (2005-2012) SETTING: A large tertiary-care center PATIENTS: Patients admitted to SICU who had MRSA surveillance cultures of the anterior nares METHODS: A random sample of banked MRSA anterior nares isolates recovered during (2005) and after (2006-2012) implementation of a daily CHG bathing protocol was examined for qacA/B genes and high-level mupirocin resistance...
May 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/26705765/the-effects-of-chlorhexidine-gluconate-bathing-on-health-care-associated-infection-in-intensive-care-units-a-meta-analysis
#12
REVIEW
Ha Yeon Kim, Woo Kyung Lee, Sungwon Na, Yun Ho Roh, Cheung Soo Shin, Jeongmin Kim
PURPOSE: The purpose was to assess the effects of chlorhexidine gluconate (CHG) bathing on health care-associated infections among critically ill patients. METHODS: This meta-analysis evaluated English-language studies from the PubMed, Embase, and Cochrane databases. The Cochrane Collaboration methodology was used to evaluate all publications regarding daily CHG bathing and the risks of acquiring central line-associated bloodstream infection (CLABSI), methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococcus (VRE)...
April 2016: Journal of Critical Care
https://www.readbyqxmd.com/read/26633158/bathing-with-2-chlorhexidine-gluconate-evidence-and-costs-associated-with-central-line-associated-bloodstream-infections
#13
Hena N Shah, Jennifer L Schwartz, Gaye Luna, Deborah L Cullen
In a coordinated national effort reported by the Agency for Healthcare Research and Quality, the use of 2% chlorhexidine gluconate (CHG) has reduced the central line-associated bloodstream infection (CLABSI) rate by 40%. Conversely, a recent randomized clinical trial determined that chlorhexidine bathing did not reduce the CLABSI rate. The objectives of this study were to conduct meta-analysis and clarify the effectiveness of 2% CHG bathing by nurses on CLABSIs in adult intensive care unit patients and to determine the contributing costs attributable to CLABSIs and 2% CHG bathing...
January 2016: Critical Care Nursing Quarterly
https://www.readbyqxmd.com/read/26137751/understanding-differing-viewpoints-on-preadmission-bathing-and-cleansing-soap-vs-chg
#14
COMMENT
Amber Wood, Ramona Conner, Lisa Spruce
No abstract text is available yet for this article.
May 2015: AORN Journal
https://www.readbyqxmd.com/read/26034956/association-of-a-bundled-intervention-with-surgical-site-infections-among-patients-undergoing-cardiac-hip-or-knee-surgery
#15
MULTICENTER STUDY
Marin L Schweizer, Hsiu-Yin Chiang, Edward Septimus, Julia Moody, Barbara Braun, Joanne Hafner, Melissa A Ward, Jason Hickok, Eli N Perencevich, Daniel J Diekema, Cheryl L Richards, Joseph E Cavanaugh, Jonathan B Perlin, Loreen A Herwaldt
IMPORTANCE: Previous studies suggested that a bundled intervention was associated with lower rates of Staphylococcus aureus surgical site infections (SSIs) among patients having cardiac or orthopedic operations. OBJECTIVE: To evaluate whether the implementation of an evidence-based bundle is associated with a lower risk of S. aureus SSIs in patients undergoing cardiac operations or hip or knee arthroplasties. DESIGN, SETTING, AND PARTICIPANTS: Twenty hospitals in 9 US states participated in this pragmatic study; rates of SSIs were collected for a median of 39 months (range, 39-43) during the preintervention period (March 1, 2009, to intervention) and a median of 21 months (range, 14-22) during the intervention period (from intervention start through March 31, 2014)...
June 2, 2015: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/25973242/impact-of-daily-bathing-with-chlorhexidine-gluconate-on-ventilator-associated-pneumonia-in-intensive-care-units-a-meta-analysis
#16
Wensen Chen, Quan Cao, Songqin Li, Huifen Li, Weihong Zhang
OBJECTIVE: Ventilator associated pneumonia (VAP) is the most important nosocomial infection in intensive care units (ICUs). Our objective was to assess whether daily bathing with chlorhexidine gluconate (CHG) would significantly result in the reduction of VAP. MATERIALS AND METHODS: Meta-analysis of randomized controlled trials (RCTs) and quasi-experimental studies were conducted. The setting are medical, surgical, trauma, and combined medical-surgical ICUs. The patients are adult...
April 2015: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/25798778/chlorhexidine-daily-bathing-impact-on-health-care-associated-infections-caused-by-gram-negative-bacteria
#17
Nadim Cassir, Guillemette Thomas, Sami Hraiech, Julie Brunet, Pierre-Edouard Fournier, Bernard La Scola, Laurent Papazian
BACKGROUND: Health care-associated infections (HAIs) are a major cause of morbidity and mortality in intensive care unit (ICU) patients. Our objective was to evaluate the impact of daily bathing with chlorhexidine gluconate (CHG) on the incidence rates of HAIs, with a focus on their causative bacteria, in a French ICU. METHODS: From March 2012-May 2013, we enrolled 325 patients with at least 1 episode of suspected sepsis in the ICU, during two 6-month periods. The intervention group was subjected daily to skin cleansing with 2% CHG-impregnated cloths, whereas the control group was bathed daily with soap and water...
June 2015: American Journal of Infection Control
https://www.readbyqxmd.com/read/25604707/insights-into-bacterial-colonization-of-intensive-care-patients-skin-the-effect-of-chlorhexidine-daily-bathing
#18
N Cassir, L Papazian, P-E Fournier, D Raoult, B La Scola
Skin is a major reservoir of bacterial pathogens in intensive care unit (ICU) patients. The aim of this study was to assess the skin bacterial richness and diversity in ICU patients and the effect of CHG daily bathing on skin microbiota. Twenty ICU patients were included during an interventional period with CHG daily bathing (n = 10) and a control period (n = 10). At day seven of hospitalization, eight skin swab samples (nares, axillary vaults, inguinal creases, manubrium and back) were taken from each patient...
May 2015: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/25222893/does-chlorhexidine-bathing-in-adult-intensive-care-units-reduce-blood-culture-contamination-a-pragmatic-cluster-randomized-trial
#19
RANDOMIZED CONTROLLED TRIAL
Edward J Septimus, Mary K Hayden, Ken Kleinman, Taliser R Avery, Julia Moody, Robert A Weinstein, Jason Hickok, Julie Lankiewicz, Adrijana Gombosev, Katherine Haffenreffer, Rebecca E Kaganov, John A Jernigan, Jonathan B Perlin, Richard Platt, Susan S Huang
OBJECTIVE: To determine rates of blood culture contamination comparing 3 strategies to prevent intensive care unit (ICU) infections: screening and isolation, targeted decolonization, and universal decolonization. DESIGN: Pragmatic cluster-randomized trial. SETTING: Forty-three hospitals with 74 ICUs; 42 of 43 were community hospitals. PATIENTS: Patients admitted to adult ICUs from July 1, 2009, to September 30, 2011...
October 2014: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/25134645/weekly-chlorhexidine-douche-does-it-reduce-healthcare-associated-bloodstream-infections
#20
Derya Seyman, Nefise Oztoprak, Hande Berk, Filiz Kizilates, Mestan Emek
BACKGROUND: Daily chlorhexidine (CHG) bathing has been used as a precaution to reduce the rate of healthcare-associated bloodstream infections (HA-BSI). The application frequency of CHG bathing remains unclear, this procedure has been implemented daily by this time. The aim of this study was to determine the efficacy of weekly whole-body douche with CHG shower gel on rates of HA-BSI. METHODS: We conducted a prospective intervention trial in medical, surgical, and anesthesiology intensive care units (ICUs) in a tertiary teaching hospital from June 2011 to November 2012...
October 2014: Scandinavian Journal of Infectious Diseases
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