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https://www.readbyqxmd.com/read/29137582/the-effectiveness-of-regional-anaesthesia-before-and-after-the-introduction-of-a-dedicated-regional-anaesthesia-service-incorporating-a-block-room
#1
A Chin, L Heywood, P Iu, A M Pelecanos, M J Barrington
Dedicated regional anaesthesia services incorporating block rooms and/or block teams may facilitate theatre efficiency and improve training in regional anaesthesia. Currently, it is unknown if a dedicated regional anaesthesia service improves the effectiveness of regional anaesthesia. In November 2013, the Royal Brisbane and Women's Hospital established a dedicated regional anaesthesia service comprising a block team and a block room. Pre-intervention (conventional model of care) registry data was retrospectively compared with post-intervention (dedicated regional anaesthesia service) audit data, with regard to pain and opioid requirement in the post-anaesthesia care unit (PACU)...
November 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29129802/treatment-of-paget-schroetter-syndrome-with-a-three-stage-approach-including-thoracoscopic-rib-resection-at-the-second-stage
#2
Osman Mahmoud, Eero Sihvo, Jari Räsänen, Leena Vikatmaa, Pirkka Vikatmaa, Maarit Venermo
OBJECTIVE: Young, active persons may suffer lifelong consequences of subclavian vein thrombosis, but the best treatment options remain unclear. On introduction of more active pharmacomechanical thrombus removal and thoracoscopic rib resection in our institution, we planned a diagnostic and treatment protocol and aimed to analyze the early, midterm, and intermediate-term results. METHODS: The study included 72 patients who were diagnosed with an upper limb deep venous thrombosis and underwent phlebography between 2006 and 2013...
November 9, 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29123636/management-of-oral-lichen-planus-by-980-nm-diode-laser
#3
Nahid Derikvand, Seyedeh Sara Ghasemi, Mohammad Moharami, Ehsan Shafiei, Nasim Chiniforush
Introduction: Oral lichen planus (OLP) is a mucocutaneous disease with uncertain etiology. As the etiology is unknown standard treatment modalities are not available. The traditional and common treatment relies on corticosteroids whether topical or systemic. In recent years, development of lasers made a proper path to use this instrument for treatment of the diseases which are refractory to conventional treatments. Previous studies in this field used CO2, ND:YAG, Excimer and some wavelength of diode lasers for the treatment of different types of lichen planus...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29123632/management-of-post-endodontic-retreatment-pain-with-low-level-laser-therapy
#4
Mohammad Asnaashari, Hengameh Ashraf, Amir Houshang Daghayeghi, Seyed Masoud Mojahedi, Saranaz Azari-Marhabi
Introduction: Pharmacotherapy with analgesics and non-steroidal anti-inflammatory drugs has been traditionally used to relief post-operative pain of endodontic treatments. However, due to the side effects reported for these drugs, some efforts have been made to decrease the post-operative pain of the endodontic treatments through laser irradiation. The present study aimed to evaluate the effects of low level laser therapy (LLLT) on the reduction of pain after root canal retreatment. Methods: In this clinical trial, 61 patients requiring endodontic retreatments in posterior teeth were selected...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29115203/cholecystectomy-for-uncomplicated-gallbladder-stones-does-not-follow-evidence-based-recommendations
#5
Benjamin Pedersen, Mark B Ellebæk, Allan Dorfelt, Niels Qvist
INTRODUCTION: The introduction of laparoscopic cholecystectomy was followed by a steep increase in the cholecystectomy rate, which has remained on an unchanged, high level. The main indication for cholecystectomy in Denmark in cases with uncomplicated gallbladder stones is socially debilitating pain. The objective of the present study was to investigate whether the indication "socially debilitating pain" was reported in the patient's file when he or she was referred to surgery. METHODS: Hospital files for all patients referred to surgical evaluation for uncomplicated gallbladder stones from Odense University Hospital's service area (approximately 449,000 inhabitants) within a one-year period (2014) were reviewed...
November 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/29114602/impact-on-quality-of-life-of-imrt-versus-3-d-conformal-radiation-therapy-in-head-and-neck-cancer-patients-a-case-control-study
#6
Edvard Abel, Ewa Silander, Jan Nyman, Mogens Bove, Leif Johansson, Thomas Björk-Eriksson, Eva Hammerlid
Objective: The purpose of this study was to prospectively and longitudinally compare the health-related quality of life (HRQOL) outcomes between head and neck (HN) cancer patients treated with parotid-sparing intensity modulated radiation therapy (IMRT) and patients treated with 3-dimensional conventional radiation therapy (3D-CRT). Methods and materials: Before and up to 12 months after treatment, HRQOL was recorded in patients with HN cancer who were referred to the Department of Oncology at Sahlgrenska University Hospital for curative IMRT...
July 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29114392/a-common-pathogen-in-an-uncommon-site-coronary-artery-stent-meticillin-resistant-staphylococcus-aureus-infection
#7
Krystle Shafer, Catalin Toma, Alison Galdys
Introduction. Coronary artery stents are an uncommon site for infection. Only a handful of case reports describe this condition, and Staphylococcus aureus is the most frequent pathogen. Although rare, coronary stent infections are associated with a high mortality rate. Case presentation. We describe the case of a 50-year-old man with a past medical history of seven prior meticillin-resistant S. aureus (MRSA) infections over the previous 12 months, who presented with fever and was found to have persistent MRSA bacteraemia...
September 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29101301/do-not-attempt-resuscitation-dnar-orders-understanding-and-interpretation-of-their-use-in-the-hospitalised-patient-in-ireland-a-brief-report
#8
Helen O'Brien, Siobhan Scarlett, Anne Brady, Kieran Harkin, Rose Anne Kenny, Jeanne Moriarty
Following the introduction of do-not-resuscitate (DNR) orders in the 1970s, there was widespread misinterpretation of the term among healthcare professionals. In this brief report, we present findings from a survey of healthcare professionals. Our aim was to examine current understanding of the term do-not-attempt-resuscitate (DNAR), decision-making surrounding DNAR and awareness of current guidelines. The survey was distributed to doctors and nurses in a university teaching hospital and affiliated primary care physicians in Dublin via email and by hard copy at educational meetings from July to December 2014...
November 3, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/29097856/studying-protocol-based-pain-management-in-the-emergency-department
#9
Akkamahadevi Patil, Madhu Srinivasarangan, Prithvishree Ravindra, Harshit Mundada
Background: Majority of the patients presenting to emergency department (ED) have pain. ED oligoanalgesia remains a challenge. Aims: This study aims to study the effect of implementing a protocol-based pain management in the ED on (1) time to analgesia and (2) adequacy of analgesia obtained. Settings and Design: Cross-sectional study in the ED. Methods: Patients aged 18-65 years of age with pain of numeric rating scale (NRS) ≥4 were included...
October 2017: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29097818/dapsone-treatment-is-efficient-against-persistent-cutaneous-and-gastrointestinal-symptoms-in-children-with-henoch-sch%C3%A3-nlein-purpura
#10
Jana Volejnikova, Jaroslav Horacek, Frantisek Kopriva
BACKGROUND: Henoch-Schönlein purpura (HSP) is a systemic disorder characterized by leukocytoclastic vasculitis involving the capillaries and by the deposition of IgA immune complexes. An association between HSP and atypical bacteria is uncommon in children. METHODS AND RESULTS: Here we report three cases of children, aged 5, 4 and 16 years, who were diagnosed with HSP associated with Mycoplasma pneumoniae or Chlamydia pneumoniae infection. In all presented cases, persistent cutaneous manifestations and abdominal pain were resistant to antibiotics and corticosteroids, but resolved during 48 h after the introduction of dapsone...
November 2, 2017: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29082318/cannabis-roots-a-traditional-therapy-with-future-potential-for-treating-inflammation-and-pain
#11
REVIEW
Natasha R Ryz, David J Remillard, Ethan B Russo
Introduction: The roots of the cannabis plant have a long history of medical use stretching back millennia. However, the therapeutic potential of cannabis roots has been largely ignored in modern times. Discussion: In the first century, Pliny the Elder described in Natural Histories that a decoction of the root in water could be used to relieve stiffness in the joints, gout, and related conditions. By the 17th century, various herbalists were recommending cannabis root to treat inflammation, joint pain, gout, and other conditions...
2017: Cannabis and Cannabinoid Research
https://www.readbyqxmd.com/read/29078599/from-full-thoracotomy-to-uniportal-video-assisted-thoracic-surgery-lessons-learned
#12
REVIEW
Eliseo Passera, Gaetano Rocco
Over the last two decades, conventional video-assisted thoracic surgery (VATS) has established itself as the preferred approach for almost all thoracic surgical procedures. The procedure provides a safe and easy approach with undisputed patient benefit at a cost acceptable to the healthcare system all over the world, in large hospitals as well as underprivileged rural areas. VATS has effectively addressed the patients' right to less scarring, trauma (both of access and intrathoracic manipulation), medication, pain, hospitalization, and early return home and work...
2017: J Vis Surg
https://www.readbyqxmd.com/read/29077050/pharmacotherapy-for-irritable-bowel-syndrome
#13
REVIEW
Michael Camilleri, Alexander C Ford
Irritable bowel syndrome (IBS) is a disorder of the brain-gut axis; the pathophysiological mechanisms include altered colonic motility, bile acid metabolism, neurohormonal regulation, immune dysfunction, alterations in the epithelial barrier and secretory properties of the gut. This article reviews the mechanisms, efficacy, and safety of current pharmacotherapy, and medications that are in phase III trials for the treatment of IBS. There remains a significant unmet need for effective treatments-particularly for the pain component of IBS-although the introduction of drugs directed at secretion, motility and a non-absorbable antibiotic provide options for the bowel dysfunction in IBS...
October 27, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29075519/evaluation-of-musculoskeletal-symptoms-among-physicians-performing-ultrasound
#14
Paweł Wareluk, Wiesław Jakubowski
AIM OF THE STUDY: Owing to its wide availability, relatively low cost and lack of negative effect on the patient, ultrasound has become the most commonly and readily used imaging modality. However, scanning for increasingly long periods of time on a given day and in a given week tends to negatively affect sonographers' health, primarily resulting with the overuse of the musculoskeletal system, as multiple muscles and joints are engaged during scanning. This research has been aimed at evaluating the prevalence and type of musculoskeletal symptoms among diagnostic medical sonographers, as well as identifying their professional profile...
September 2017: Journal of Ultrasonography
https://www.readbyqxmd.com/read/29071032/comparative-effectiveness-of-low-level-laser-therapy-and-transcutaneous-electric-nerve-stimulation-on-temporomandibular-joint-disorders
#15
Massoud Seifi, Asghar Ebadifar, Sattar Kabiri, Mohammad Reza Badiee, Zahra Abdolazimi, Parisa Amdjadi
Introduction: Temporomandibular joint disorders (TMDs) are the most common source of pain on the face. There are multiple etiologies, and several types of treatment have been reported. The use of non-invasive and reversible therapies in the treatment of such problems is recommended. The present study evaluated the effect of low-level laser (LLL) therapy and transcutaneous electric nerve stimulation (TENS) on TMDs. Methods: In this single-blind study, 40 patients with temporomandibular disorders were randomly divided into four groups: TENS (TENSTem dental), LLL (diode 810 nm CW), shamTENS, and sham-LLL...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29071029/safety-and-effectiveness-of-low-level-laser-therapy-in-patients-with-knee-osteoarthritis-a-systematic-review-and-meta-analysis
#16
REVIEW
Seyed Mansour Rayegani, Seyed Ahmad Raeissadat, Saeed Heidari, Mohammad Moradi-Joo
Introduction: Low-level laser therapy (LLLT) was introduced as an alternative non-invasive treatment for osteoarthritis, but its effectiveness is still controversial. The main objective of this article was to determine the safety and efficacy of LLLT in patients with knee osteoarthritis (KOA). Methods: In order to gather evidence, main medical databases as well as relevant websites were browsed without time limit. We searched with appropriate keywords and strategies. After quality assessment of studies, study data were extracted by two reviewers...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29063118/-dream-a-multifunctional-transcriptional-regulator
#17
Zi-Bing Fu, Xu-Bo Duan, Li-Na Li, Xiao-Kang Lei, Ye Jiang, Chen Wang, Han-Xiao Xu, Yin-Lian Zhang, Jiao-Hua Jiang, Rui-Chao Chai, Xi-Hua Jia, Albert Cheung Hoi Yu
DREAM (downstream regulatory element antagonist modulator), Calsenilin and KChIP3 (potassium channel interacting protein 3) belong to the neuronal calcium sensor (NCS) superfamily, which transduces the intracellular calcium signaling into a variety of activities. They are encoded by the same gene locus, but have distinct subcellular locations. DREAM was first found to interact with DRE (downstream regulatory element) site in the vicinity of the promoter of prodynorphin gene to suppress gene transcription. Calcium can disassemble this interaction by binding reversibly to DREAM protein on its four EF-hand motifs...
October 25, 2017: Sheng Li Xue Bao: [Acta Physiologica Sinica]
https://www.readbyqxmd.com/read/29058990/introduction-to-the-theme-new-approaches-for-studying-drug-and-toxicant-action-applications-to-drug-discovery-and-development
#18
Paul A Insel, Susan G Amara, Terrence F Blaschke, Urs A Meyer
The theme "New Approaches for Studying Drug and Toxicant Action: Applications to Drug Discovery and Development" links 13 articles in this volume of the Annual Review of Pharmacology and Toxicology (ARPT). The engaging prefatory articles by Arthur Cho and Robert Lefkowitz set the stage for this theme and for the reviews that insightfully describe new approaches that advance research and discovery in pharmacology and toxicology. Examples include the progress being made in developing Organson- Chips/microphysiological systems and human induced pluripotent stem cell (iPSC)-derived cells to aid in understanding cell and tissue pharmacokinetics, action, and toxicity; the recognition of the importance of circadian rhythm, the microbiome, and epigenetics in drug and toxicant responses; and the application of results from new types of patient-derived information to create personalized/precision medicine, including therapeutics for pain, which may perhaps provide help in dealing with the opioid epidemic in the United States...
October 20, 2017: Annual Review of Pharmacology and Toxicology
https://www.readbyqxmd.com/read/29049826/bilateral-uniportal-video-assisted-thoracoscopic-lung-resections
#19
Firas Emad Abu Akar, Hui Zheng, Gaser Ali, Xiaogang Zhao
The introduction of uniportal video-assisted thoracoscopic surgery into the field of minimally invasive thoracic surgery has its revolutionary effect by bringing the surgical trauma to the minimum. As a result, less postoperative pain and complications may be achieved through this technology. This may convince us as thoracic surgeons to become more liberal and to extend the indications of performing 'single-staged' bilateral video-assisted thoracoscopic surgery. Herein, we described our technique in bilateral pulmonary resections...
July 12, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29046077/cost-effectiveness-of-routine-imaging-of-suspected-appendicitis
#20
N D'Souza, M Marsden, S Bottomley, N Nagarajah, F Scutt, S Toh
Introduction The misdiagnosis of appendicitis and consequent removal of a normal appendix occurs in one in five patients in the UK. On the contrary, in healthcare systems with routine cross-sectional imaging of suspected appendicitis, the negative appendicectomy rate is around 5%. If we could reduce the rate in the UK to similar numbers, would this be cost effective? This study aimed to calculate the financial impact of negative appendicectomy at the Queen Alexandra Hospital and to explore whether a policy of routine imaging of such patients could reduce hospital costs...
October 19, 2017: Annals of the Royal College of Surgeons of England
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