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https://www.readbyqxmd.com/read/29777846/an-academic-tertiary-referral-center-s-experience-with-a-vascular-surgery-based-uterine-artery-embolization-program
#1
Naiem Nassiri, Adrian Balica, Nolan C Cirillo-Penn, Dustin Tyler Crystal, Gloria A Bachmann
OBJECTIVE: Despite growing endovascular experience within the vascular surgery community, some catheter-based interventions - such as uterine artery embolization (UAE) - remain outside the clinical scope of most vascular surgeons, owing in part to established referral patterns and limited awareness among referring colleagues. We present our experience with a vascular surgery-based, multidisciplinary UAE program at an academic tertiary referral center. METHODS: In a collaborative effort between vascular surgery and gynecology, a Pelvic Vascular Disease Program has been established to provide palliative, prophylactic, and therapeutic embolizations including, but not limited to, UAE...
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29777799/title-studies-on-drug-switchability-showed-heterogeneity-in-methodological-approaches-a-scoping-review
#2
REVIEW
Valeria Belleudi, Francesco Trotta, Simona Vecchi, Laura Amato, Antonio Addis, Marina Davoli
BACKGROUND: Several drugs share the same therapeutic indication, including those undergoing patent expiration. Concerns on the interchangeability are frequent in clinical practice, challenging the evaluation of switchability through observational research. AIM: To conduct a scoping review of observational studies on drug switchability to identify methodological strategies adopted to deal with bias and confounding. METHODS: We searched PubMed, EMBASE, and Web of Science (updated 1/31/2017) to identify studies evaluating switchability in terms of effectiveness/safety outcomes or compliance...
May 16, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29777420/what-role-do-masculine-norms-play-in-men-s-hiv-testing-in-sub-saharan-africa-a-scoping-review
#3
REVIEW
Katelyn M Sileo, Rebecca Fielding-Miller, Shari L Dworkin, Paul J Fleming
Men living with HIV/AIDS in sub-Saharan Africa are less likely to test for HIV than women. We conducted a scoping review in May of 2016 to identify how masculine norms influence men's HIV testing in sub-Saharan Africa. Our review yielded a total of 13 qualitative studies from 8 countries. Masculine norms create both barriers and facilitators to HIV testing. Barriers included emotional inexpression, gendered communication, social pressures to be strong and self-reliant, and the fear that an HIV positive result would threaten traditional social roles (i...
May 18, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29777392/determining-representative-ranges-of-point-sensors-in-distributed-networks
#4
John K Horne, Dale A Jacques
Distributed networks of stationary instruments provide high temporal scope (i.e., range/resolution) observations but are spatially limited as a set of point measurements. Measurement similarity between points typically decays with distance, which is used to set interpolation distances. The importance of analyzing spatiotemporal data at equivalent spatial and temporal scales has been identified but no standard procedure is used to interpolate space using temporally-indexed observations. Using concurrent mobile and stationary active acoustic, fish density data from a tidal energy site in Puget Sound, WA, USA, six methods are compared to estimate the range at which stationary measurements can be spatially interpolated...
May 18, 2018: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29776453/dye-residue-analysis-in-raw-and-processed-aquaculture-products-matrix-extension-of-aoac-international-official-method-%C3%A2-2012-25
#5
Wendy C Andersen, Christine R Casey, Tara J Nickel, Susan L Young, Sherri B Turnipseed
Background : Triphenylmethane dyes and metabolites are known or suspected mutagens and areprohibited in animals intended for human consumption. Despite toxicity, triphenylmethane dyes are used illegally as inexpensive treatments for fungal and parasite infections in aquatic animals. Objective: AOAC INTERNTIONAL Official Method ℠ 2012.25 for the LC-MS/MS determination of malachite green, crystal violet, brilliant green, and metabolites leucomalachite green and leucocrystal violet in seafood products was previously validated for finfish (trout, salmon, catfish, and tilapia) and shrimp, but had not been fully validated for other types of aquacultured products such as eel, molluscan shellfish, or frog or for processed seafoods...
May 18, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29775993/postnatal-psychosocial-assessment-and-clinical-decision-making-a-descriptive-study
#6
Deborah Sims, Cathrine Fowler
AIM: The aim of this study is to describe experienced child and family health nurses' clinical decision-making during a postnatal psychosocial assessment. BACKGROUND: Maternal emotional wellbeing in the postnatal year optimises parenting and promotes infant development. Psychosocial assessment potentially enables early intervention and reduces the risk of a mental disorder occurring during this time of change. Assessment accuracy, and the interventions used are determined by the standard of nursing decision-making...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29775969/the-scale-on-community-care-perceptions-scope-for-nursing-students-a-development-and-psychometric-validation-study
#7
Margriet van Iersel, Rien de Vos, Corine Latour, Paul A Kirschner, Wilma Scholte Op Reimer
The aim of this study was to develop a valid instrument to measure student nurses' perceptions of community care (SCOPE). DeVellis' staged model for instrument development and validation was used. Scale construction of SCOPE was based on existing literature. Evaluation of its psychometric properties included exploratory factor analysis and reliability analysis. After pilot-testing, 1062 bachelor nursing students from six institutions in the Netherlands (response rate 81%) took part in the study. SCOPE is a 35-item scale containing: background variables, 11 measuring the affective component, 5 measuring community care perception as a placement, 17 as a future profession, and 2 on the reasons underlying student preference...
May 11, 2018: Nurse Education in Practice
https://www.readbyqxmd.com/read/29775929/negative-impacts-of-elevated-nitrate-on-physiological-performance-are-not-exacerbated-by-low-ph
#8
Daniel F Gomez Isaza, Rebecca L Cramp, Craig E Franklin
Multiple environmental stressors, including nutrient effluents (i.e. nitrates [NO3 - ]) and altered pH regimes, influence the persistence of freshwater species in anthropogenically disturbed habitats. Independently, nitrate and low pH affect energy allocation by increasing maintenance costs and disrupting oxygen uptake, which ultimately results in impacts upon whole animal performance. However, the interaction between these two stressors has not been characterised. To address this, the effects of nitrate and pH and their interaction on aerobic scope and physiological performance were investigated in the blueclaw crayfish, Cherax destructor...
May 15, 2018: Aquatic Toxicology
https://www.readbyqxmd.com/read/29775924/public-project-success-as-seen-in-a-broad-perspective-lessons-from-a-meta-evaluation-of-20-infrastructure-projects-in-norway
#9
Gro Holst Volden
Infrastructure projects in developed countries are rarely evaluated ex-post. Despite their number and scope, our knowledge about their various impacts is surprisingly limited. The paper argues that such projects must be assessed in a broad perspective that includes both operational, tactical and strategic aspects, and unintended as well as intended effects. A generic six-criteria evaluation framework is suggested, inspired by a framework frequently used to evaluate development assistance projects. It is tested on 20 Norwegian projects from various sectors (transport, defence, ICT, buildings)...
April 30, 2018: Evaluation and Program Planning
https://www.readbyqxmd.com/read/29775874/emotion-regulation-as-a-predictor-of-the-endocrine-autonomic-affective-and-symptomatic-stress-response-and-recovery
#10
Katarina Krkovic, Annika Clamor, Tania M Lincoln
Stress is associated with the development of mental disorders such as depression and psychosis. The ability to regulate emotions is likely to influence how individuals respond to and recover from acute stress, and may thus be relevant to symptom development. To test this, we investigated whether self-reported emotion regulation predicts the endocrine, autonomic, affective, and symptomatic response to and recovery from a stressor. Social-evaluative stress was induced by the Trier Social Stress Test (TSST) in N = 67 healthy individuals (53...
April 30, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29775290/manganese-mediated-reductive-transamidation-of-tertiary-amides-with-nitroarenes
#11
Chi Wai Cheung, Jun-An Ma, Xile Hu
Amides are an important class of organic compounds, which have widespread industrial applications. Transamidation of amides is a convenient method to generate new amides from existing ones. Tertiary amides, however, are challenging sub-strates for transamidation. Here we describe an unconvention-al approach to the transamidation of tertiary amides using nitroarenes as the nitrogen source under reductive conditions. Manganese metal alone mediates the reactions and no additional catalyst is required. The method exhibits broad scope and high functional group tolerance...
May 18, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29775070/lewis-acid-br%C3%A3-nsted-acid-controlled-pd-ii-catalyzed-chemodivergent-functionalization-of-c-sp-2-h-bonds-with-n-arylthio-i-a-mides
#12
Manthena Chaitanya, Pazhamalai Anbarasan
An efficient and chemodivergent palladium-catalyzed thiolation (C-S) and imidation (C-N) of directing group-assisted C-H bonds have been accomplished employing N-(arylthio)imides in combination with either Brønsted acid or Lewis acid, respectively. Notable features of the developed methodologies include excellent diversity, high functional group tolerance, wide substrate scope, and use of a single N-S reagent. Importantly, the developed hypothesis was also successfully extended to the amidation of C-H bonds...
May 18, 2018: Organic Letters
https://www.readbyqxmd.com/read/29774609/nanosheets-of-nonlayered-aluminum-metal-organic-frameworks-through-a-surfactant-assisted-method
#13
Alexey Pustovarenko, Maarten G Goesten, Sumit Sachdeva, Meixia Shan, Zakariae Amghouz, Youssef Belmabkhout, Alla Dikhtiarenko, Tania Rodenas, Damla Keskin, Ilja K Voets, Bert M Weckhuysen, Mohamed Eddaoudi, Louis C P M de Smet, Ernst J R Sudhölter, Freek Kapteijn, Beatriz Seoane, Jorge Gascon
During the last decade, the synthesis and application of metal-organic framework (MOF) nanosheets has received growing interest, showing unique performances for different technological applications. Despite the potential of this type of nanolamellar materials, the synthetic routes developed so far are restricted to MOFs possessing layered structures, limiting further development in this field. Here, a bottom-up surfactant-assisted synthetic approach is presented for the fabrication of nanosheets of various nonlayered MOFs, broadening the scope of MOF nanosheets application...
May 17, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29774335/synthons-for-carbide-complex-chemistry
#14
Anders Reinholdt, Anthony F Hill, Jesper Bendix
The sterically accessible carbide complex, (Cy3P)Cl3Ru[triple bond, length as m-dash]C-PtCl(py)2, acts as a synthon for terminal and bridging carbide fragments that relocate to pincer and A-frame scaffolds upon ligand addition. This concept, benefitting from coordination sphere selection as the concluding step, confronts traditional synthetic strategies and broadens the scope for carbide complexes.
May 18, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29774140/three-dimensional-printing-in-maxillofacial-surgery-hype-versus-reality
#15
Alaa Aldaadaa, Nazanin Owji, Jonathan Knowles
Three-dimensional printing technology is getting more attention recently, especially in the craniofacial region. This is a review of literature enlightening the materials that have been used to date and the application of such technology within the scope of maxillofacial surgery.
January 2018: Journal of Tissue Engineering
https://www.readbyqxmd.com/read/29773611/charlie-gard-and-the-weight-of-parental-rights-to-seek-experimental-treatment
#16
Giles Birchley
The case of Charlie Gard, an infant with a genetic illness whose parents sought experimental treatment in the USA, brought important debates about the moral status of parents and children to the public eye. After setting out the facts of the case, this article considers some of these debates through the lens of parental rights. Parental rights are most commonly based on the promotion of a child's welfare; however, in Charlie's case, promotion of Charlie's welfare cannot explain every fact of the case. Indeed, some seem most logically to extend from intrinsic parental rights, that is, parental rights that exist independent of welfare promotion...
May 17, 2018: Journal of Medical Ethics
https://www.readbyqxmd.com/read/29773059/biomedical-applications-of-glycoconjugates
#17
Fei Ding, Yongmin Zhang
Glycans expressed on the forefront surface of cells participate in many key biological processes via forming various glycoconjugates. The recognition of complex glycoconjugates as mediators of important biological processes has stimulated investigation into their therapeutic potential. As the increasing accessibility of glycoconjugates, it has been widely applied in the field of drug delivery. This review particularly refers to the constitutive glycoconjugates of receptor-mediated binding of glycoprotein, glycolipids and glycopeptides for cell-selective drug delivery, in order to broaden the future therapeutic scope of drug delivery system and effective cancer therapy...
May 17, 2018: Mini Reviews in Medicinal Chemistry
https://www.readbyqxmd.com/read/29773013/critical-review-on-curcumin-as-a-therapeutic-agent-from-traditional-herbal-medicine-to-an-ideal-therapeutic-agent
#18
Muhammad Usman Akbar, Kanwal Rehman, Khalid Mahmood Zia, Muhammad Imran Qadir, Muhammad Sajid Hamid Akash, Muhammad Ibrahim
Traditionally, many natural medicinal plants have been used to treat a variety of diseases since ancient times and are considered a potential source of phytochemicals for the development of new drugs. One of these is curcumin, which is an easily accessible, inexpensive, and nontoxic bioactive compound. Curcumin is a very important, naturally occurring, and highly lipophilic and phenolic substance derived from the rhizomes of plant Curcuma longa, a member of the Zingiberaceae (ginger) family, which is mostly used as a curry spice, flavoring agent, insect repellent, coloring agent in food, traditional drug, and ingredient in cosmetics...
2018: Critical Reviews in Eukaryotic Gene Expression
https://www.readbyqxmd.com/read/29772924/access-to-care-among-children-with-disabilities-enrolled-in-the-masshealth-commonhealth-buy-in-program
#19
Melissa Hirschi, Angela Wangari Walter, Kasey Wilson, Kate Jankovsky, Beth Dworetzky, Meg Comeau, Sara S Bachman
Children with disabilities utilize more health-care services and incur higher costs than other children do. Medicaid Buy-In programs for children with disabilities have the potential to increase access to benefits while reducing out-of-pocket costs for families whose income exceeds Medicaid eligibility. This study sought to understand how parents and caregivers of Massachusetts children with disabilities perceive access to care under CommonHealth, Massachusetts's Medicaid Buy-In program. Parents and caregivers ( n = 615) whose children were enrolled in CommonHealth participated in a survey assessing the impact of the program...
January 1, 2018: Journal of Child Health Care: for Professionals Working with Children in the Hospital and Community
https://www.readbyqxmd.com/read/29772845/doxycycline-impairs-mitochondrial-function-and-protects-human-glioma-cells-from-hypoxia-induced-cell-death-implications-of-using-tet-inducible-systems
#20
Anna-Luisa Luger, Benedikt Sauer, Nadja I Lorenz, Anna L Engel, Yannick Braun, Martin Voss, Patrick N Harter, Joachim P Steinbach, Michael W Ronellenfitsch
Inducible gene expression is an important tool in molecular biology research to study protein function. Most frequently, the antibiotic doxycycline is used for regulation of so-called tetracycline (Tet)-inducible systems. In contrast to stable gene overexpression, these systems allow investigation of acute and reversible effects of cellular protein induction. Recent reports have already called for caution when using Tet-inducible systems as the employed antibiotics can disturb mitochondrial function and alter cellular metabolism by interfering with mitochondrial translation...
May 17, 2018: International Journal of Molecular Sciences
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