Leonie Grosse, Victoria Lieftüchter, Yannik Vollmuth, Florian Hoffmann, Martin Olivieri, Karl Reiter, Moritz Tacke, Florian Heinen, Ingo Borggraefe, Andreas Osterman, Maria Forstner, Johannes Hübner, Ulrich von Both, Lena Birzele, Meino Rohlfs, Adrian Schomburg, Merle M Böhmer, Viktoria Ruf, Dániel Cadar, Birgit Muntau, Kirsten Pörtner, Dennis Tappe
BACKGROUND: The Borna disease virus (BoDV-1) is an emerging zoonotic virus causing severe and mostly fatal encephalitis in humans. METHODS AND RESULTS: A local cluster of fatal BoDV-1 encephalitis cases was detected in the same village three years apart affecting two children. While the first case was diagnosed late in the course of disease, a very early diagnosis and treatment attempt facilitated by heightened awareness was achieved in the second case. Therapy started as early as day 12 of disease...
February 23, 2023: Infection