keyword
MENU ▼
Read by QxMD icon Read
search

Spinal tumours

keyword
https://www.readbyqxmd.com/read/29325524/posterior-decompression-and-occipitocervical-fixation-followed-by-intraoperative-vertebroplasty-for-metastatic-involvement-of-the-axis
#1
Xinjie Wu, Mingsheng Tan, Yingna Qi, Ping Yi, Feng Yang, Xiangsheng Tang, Qingying Hao
BACKGROUND: Metastases to the upper cervical spine were rarely reported in the literature. However, metastases to this area may cause spinal instability and cord compression, which in turn can result in respiratory failure and neurological dysfunction. The present study investigated the efficacy and safety of posterior decompression and occipitocervical fixation followed by intraoperative vertebroplasty for this disease. METHODS: This was a retrospective study that included 10 patients with metastatic involvement of the axis from March 2002 to May 2014...
January 11, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29234845/eanm-guideline-for-radionuclide-therapy-with-radium-223-of-metastatic-castration-resistant-prostate-cancer
#2
Thorsten D Poeppel, Daria Handkiewicz-Junak, Michael Andreeff, Alexander Becherer, Andreas Bockisch, Eva Fricke, Lilli Geworski, Alexander Heinzel, Bernd J Krause, Thomas Krause, Markus Mitterhauser, Wilfried Sonnenschein, Lisa Bodei, Roberto C Delgado-Bolton, Michael Gabriel
Radium Ra-223 dichloride (radium-223, Xofigo®) is a targeted alpha therapy approved for the treatment of castration-resistant prostate cancer (CRPC) with symptomatic bone metastases and no known visceral metastatic disease. Radium-223 is the first targeted alpha therapy in this indication providing a new treatment option, with evidence of a significant survival benefit, both in overall survival and in the time to the first symptomatic skeletal-related event. The skeleton is the most common metastatic site in patients with advanced prostate cancer...
December 12, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29204734/basic-concepts-in-metal-work-failure-after-metastatic-spine-tumour-surgery
#3
REVIEW
Naresh Kumar, Ravish Patel, Anshuja Charvi Wadhwa, Aravind Kumar, Helena Maria Milavec, Dhiraj Sonawane, Gurpal Singh, Lorin Michael Benneker
PURPOSE: The development of spinal implants marks a watershed in the evolution of metastatic spine tumour surgery (MSTS), which has evolved from standalone decompressive laminectomy to instrumented stabilization and decompression with reconstruction when necessary. Fusion may not be feasible after MSTS due to poor quality of graft host bed along with adjunct chemotherapy and/or radiotherapy postoperatively. With an increase in the survival of patients with spinal tumours, there is a probability of an increase in the rate of implant failure...
December 4, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29204290/meningeal-carcinomatosis-and-spinal-cord-infiltration-caused-by-a-locally-invasive-pulmonary-adenocarcinoma-in-a-cat
#4
Christoforos Posporis, Llorenç Grau-Roma, Olga Travetti, Maria Oliveira, Laura Polledo, Annette Wessmann
Case summary: A 12-year-old domestic shorthair cat was presented with acute non-painful hindlimb proprioceptive ataxia localising to T3-L3 spinal cord segments. MRI revealed paravertebral muscular hyperintensity on T2-weighted images at the level of T7-T8 vertebrae. The cat improved on conservative management but deteriorated 3 months later. Repeated MRI showed meningeal enhancement at the same level and hyperintensity of the paravertebral musculature extending to the right thoracic wall and pleural space on short tau inversion recovery images...
July 2017: JFMS open reports
https://www.readbyqxmd.com/read/29199465/12-years-delayed-postoperative-spinal-recurrence-of-craniopharyngioma-case-report-and-literature-review
#5
Nicolò Marchesini, Christian Soda, Umberto Maria Ricci, Mattia Sedia, Francesco Sala, Giampietro Pinna
A case of delayed spinal adamantinomatous craniopharyngioma recurrence is presented. A 54-year-old male patient was admitted in our Emergency Department complaining of urinary disorders and leg pains. He underwent surgical removal of intraventricular craniopharyngioma 12 years previously. On MR imaging a well-circumscribed intradural cistyc mass at the T12 level was reavealed. A T11 and T12 laminotomy was performed and total removal of the tumour was achieved. Histology examination showed adamantinous craniopharyngioma...
December 4, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29188529/spinal-ependymomas-in-nf2-a-surgical-disease
#6
M Kalamarides, W Essayed, J P Lejeune, R Aboukais, O Sterkers, D Bernardeschi, M Peyre, S K Lloyd, S Freeman, C Hammerbeck-Ward, M Kellett, S A Rutherford, D G Evans, O Pathmanaban, A T King
The management of spinal cord ependymomas in Neurofibromatosis Type 2 (NF2) has traditionally been conservative, in contrast to the management of sporadic cases; the assumption being that, in the context of NF2, they did not cause morbidity. With modern management and improved outcome of other NF2 tumours, this assumption, and therefore the lack of role for surgery, has been questioned. To compare the outcome of conservative treatment of spinal ependymomas in NF2 with surgical intervention in selected patients...
November 29, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29181871/outcome-of-9-dogs-treated-with-stereotactic-radiation-therapy-for-primary-or-metastatic-vertebral-osteosarcoma
#7
K E Swift, S M LaRue
Primary and metastatic vertebral osteosarcoma (OSA) in the dog carries an overall guarded prognosis. Previously reported definitive treatments in dogs with vertebral OSA have included surgery, radiotherapy, chemotherapy or a combination of those therapies. This retrospective study was completed to determine patterns of failure, duration of local control and survival time in dogs with vertebral OSA treated with stereotactic radiation therapy (SRT). Nine dogs were treated with SRT for vertebral OSA. Protocols ranged from 1 to 5 fractions with total prescription ranging from 13...
November 27, 2017: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/29169628/spinal-cord-compression-in-a-horse-due-to-a-granular-cell-variant-of-neurofibroma
#8
A N E Civello, B Dunkel, B A Summers, H M Martineau
A neurofibroma of granular cell subtype is described in a 7-year-old horse. The horse had a 3-month history of ataxia affecting the forelimbs and hindlimbs, suggesting a C1-C6 neuroanatomical localization. Post-mortem examination revealed an intradural mass arising from the right sixth cervical spinal nerve and compressing the spinal cord. Histologically, the mass was composed largely of wavy spindle cells (a mixture of Schwann cells, perineurial cells and fibroblasts) intimately associated with ropy collagen fibres...
November 2017: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/29160114/complex-spinal-fixation-of-a-cervical-vertebra-brown-tumour-report-of-an-unusual-case
#9
Sebastian Miguel Toescu, Maria Ibrahim, Dominic G O'Donovan, Gowrie Balasubramaniam, Karoly M David
Brown tumours affecting the cervical spine are a rare but recognised complication of renal failure-related secondary hyperparathyroidism. We present a case of a 26 year-old female with radiculopathy who was managed successfully with 360° cervical spine fixation and parathyroidectomy.
November 21, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29143901/combined-vertebral-augmentation-and-radiofrequency-ablation-in-the-management-of-spinal-metastases-an-update
#10
REVIEW
Ning Mao Kam, Julian Maingard, Hong Kuan Kok, Dinesh Ranatunga, Duncan Brooks, William C Torreggiani, Peter L Munk, Michael J Lee, Ronil V Chandra, Hamed Asadi
Spinal metastases are the most commonly encountered tumour of the spine, occurring in up to 40% of patients with cancer. Each year, approximately 5% of cancer patients will develop spinal metastases. This number is expected to increase as the life expectancy of cancer patients increases. Patients with spinal metastases experience severe and frequently debilitating pain, which often decreases their remaining quality of life. With a median survival of less than 1 year, the goals of treatment in spinal metastases are reducing pain, improving or maintaining level of function and providing mechanical stability...
November 16, 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/29140834/prognostic-factors-in-patients-with-metastatic-spinal-cord-compression-secondary-to-melanoma-a-systematic-review
#11
Nicholas J Hadden, Jerome R D McIntosh, Samuel Jay, Paula J Whittaker
Melanoma is one of the most common primary tumours associated with metastatic spinal cord compression (MSCC). The aim of this review is to identify prognostic factors specifically for MSCC secondary to melanoma. A systematic search of literature was performed in MEDLINE, Embase and the Cochrane Library to identify studies reporting prognostic factors for patients with MSCC secondary to melanoma. Two studies, involving a total of 39 patients, fulfilled the inclusion criteria. The variables associated with increased survival were receiving postoperative radiotherapy, receiving chemotherapy, perioperative lactate dehydrogenase level less than or equal to 8...
November 14, 2017: Melanoma Research
https://www.readbyqxmd.com/read/29131086/intracranial-epidural-haematoma-following-surgical-removal-of-a-giant-lumbosacral-schwannoma-a-case-report-and-literature-review
#12
Jakob Nemir, Vjerislav Peterković, Ines Trninić, Ivan Domazet, Hrvoje Barić, Miroslav Vukić
Postoperative intracranial epidural haematoma (EDH) is an extremely rare complication following spinal surgery, with only a handful of cases described in the literature. We report the case of a 16-year-old girl who underwent a successful subtotal resection of a giant lumbosacral schwannoma (L2-S2 level). Recovery from general anaesthesia was uneventful; however, her neurological status deteriorated rapidly within 24 h after surgery. A head computed tomography scan revealed a large right frontoparietal EDH with midline shift...
November 11, 2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29073497/therapeutic-approaches-for-protecting-bone-health-in-patients-with-breast-cancer
#13
REVIEW
Diana Lüftner, Daniela Niepel, Guenther G Steger
Improvements in the survival of patients with breast cancer, together with a better understanding of the pathology of the disease, have led to the emergence of bone health as a key aspect of patient management. Patients with breast cancer are typically at risk of skeletal complications throughout their disease course. The receptor activator of nuclear factor κ B ligand (RANKL) inhibitor denosumab and bisphosphonates (e.g. zoledronic acid) are approved in Europe for the prevention of skeletal-related events (pathologic fracture, radiation or surgery to bone, and spinal cord compression) in adults with bone metastases secondary to solid tumours...
October 23, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29071122/diagnostic-algorithm-prognostic-factors-and-surgical-treatment-of-metastatic-cancer-diseases-of-the-long-bones-and-spine
#14
REVIEW
Miklós Szendrői, Imre Antal, Attila Szendrői, Áron Lazáry, Péter Pál Varga
Oncological management of skeletal metastases has changed dramatically in the last few decades. A significant number of patients survive for many years with their metastases.Surgeons are more active and the technical repertoire is broader, from plates to intramedullary devices to (tumour) endoprostheses.The philosophy of treatment should be different in the case of a trauma-related fracture and a pathological fracture. A proper algorithm for establishing a diagnosis and evaluation of prognostic factors helps in planning the surgical intervention...
September 2017: EFORT open reviews
https://www.readbyqxmd.com/read/29057366/spinal-tumour-primary-cervical-extradural-meningioma-at-an-unusual-location
#15
Ishita Pant, Vinod Kumar Singh Gautam, Rima Kumari, Sujata Chaturvedi
Extradural spinal meningiomas are extremely rare, more so in the cervical region. A purely extradural location as reported in this paper is quite exceptional. The authors report a case of extradural meningioma in a 50-year-old male located in the cervical spine that was surgically treated with the provisional diagnosis of a neurofibroma. Histopathological diagnosis of meningothelial meningioma was made with the routine hematoxylin and eosin (HE) stain. The origin, clinical course, radiological features, pathological findings with the differential diagnosis and surgical treatment are discussed based on a review of the literature...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29057339/composite-peek-carbon-fiber-implants-can-increase-the-effectiveness-of-radiotherapy-in-the-management-of-spine-tumors
#16
Giuseppe Tedesco, Alessandro Gasbarrini, Stefano Bandiera, Riccardo Ghermandi, Stefano Boriani
BACKGROUND: Combination of surgery and radiotherapy in the treatment of primary spine tumour can be indicated in some cases where a satisfactory oncological margin cannot be achieved. The presence of metal hardware has always limited post-operative radiotherapy due to the scattering effects of ionizing radiation or particles. The use of a fixation system (including rods and screw) fully made in PEEK embedded Carbon fiber (CFR-PEEK) could make easier and more effective the post-operative radiotherapy as it is radiolucent and does not interfere with ionizing radiation and accelerated particles...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29052449/resveratrol-in-management-of-bone-and-spinal-cancers
#17
Gang Chen, Hong Xia, Zhi-Guo Zhang, Hai-Liang Yu
Bone cancer is a malignant primary tumour of the bone with different typing, such as, osteosarcoma, chondrosarcoma, Ewing's sarcoma and fibrosarcoma. Despite the clinical efficacy of conventional therapies of bone cancer, most patients eventually relapse and the disease remains incurable. Therefore, new therapeutic strategies are needed to improve patient outcome. In this review article, we have discussed the role of resveratrol in preventing bone and spinal cancers and therapeutics. Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural polyphenol, which has been widely reported as an anticancer molecule...
October 20, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29024203/megestrol-acetate-caused-adrenal-insufficiency-and-delayed-puberty-in-a-male-adolescent-with-spinal-tumour
#18
Chutima Leelalertlauw, Pat Mahachoklertwattana, Suradej Hongeng, Preamrudee Poomthavorn
No abstract text is available yet for this article.
October 12, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29021680/nondysraphic-cervicomedullary-intramedullary-lipoma
#19
Sujeet Kumar Meher, Laxmi Narayan Tripathy, Harsh Jain, Sunandan Basu
Spinal cord lipomas are usually associated with spinal dysraphism and is most common in lumbosacral region. Spinal intradural lipoma is a rare condition accounting for less than 1% of spinal cord tumours and is most prevalent in cervicodorsal region. Intramedullary spinal cord lipoma of cervical spine not associated with spinal dysraphism is one of the rarest lesions. They usually present insidiously with slowly progressive myelopathic deficits. We present a case of nondysraphic intramedullary spinal cord lipoma with exophytic component and intracranial extension...
July 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/28987657/feasibility-of-percutaneous-cryoablation-of-vertebral-metastases-under-local-anaesthesia-in-asaiii-patients
#20
Alessandro Motta, Giuseppe Caltabiano, Stefano Palmucci, Giovanni Failla, Antonio Basile
PURPOSE: spine metastases are common concern from several primary neoplasms, modern management include percutaneous techniques such as ablation and cementoplasty. This research aims to evaluate the treatment under local anaesthesia in high-risk patients (ASA III). METHODS AND MATERIAL: from January 2013 up to September 2016 we treated via percutaneous cryoablation 11 advanced oncological patients classified as ASA III, then retrospectively a review of their clinical history has been performed...
October 2017: European Journal of Radiology
keyword
keyword
114974
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"