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Blood lipid burden

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https://www.readbyqxmd.com/read/28283980/alleviating-the-environmental-heat-burden-on-laying-hens-by-feeding-on-diets-enriched-with-certain-antioxidants-vitamin-e-and-selenium-individually-or-combined
#1
Mohamed E Abd El-Hack, Khalid Mahrose, Muhammad Arif, Maria Tabassum Chaudhry, Islam M Saadeldin, Muhammad Saeed, Rab Nawaz Soomro, Imtiaz Hussain Raja Abbasi, Zaib Ur Rehman
The present study was designed to alleviate the negative biohazards of high ambient temperature on the productive performance and physiological status of laying hens. A total of 135 Bovans laying hens were distributed into nine groups in a 3 × 3 factorial design experiment. Basal diet was supplemented with vitamin E at levels of 0, 250, and 500 mg /kg diet. Within each dietary vitamin E level, each diet was supplemented with sodium selenite as a source of selenium (Se) to supply 0, 0.25, and 0.50 mg Se/kg diet...
March 11, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28263370/fixed-dose-combination-therapy-for-the-prevention-of-atherosclerotic-cardiovascular-diseases
#2
REVIEW
Ehete Bahiru, Angharad N de Cates, Matthew Rb Farr, Morag C Jarvis, Mohan Palla, Karen Rees, Shah Ebrahim, Mark D Huffman
BACKGROUND: Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death and disability worldwide, yet ASCVD risk factor control and secondary prevention rates remain low. A fixed-dose combination of blood pressure- and cholesterol-lowering and antiplatelet treatments into a single pill, or polypill, has been proposed as one strategy to reduce the global burden of ASCVD. OBJECTIVES: To determine the effect of fixed-dose combination therapy on all-cause mortality, fatal and non-fatal ASCVD events, and adverse events...
March 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28228373/statins-and-fibrates-for-diabetic-retinopathy-protocol-for-a-systematic-review
#3
Vania Mozetic, Carolina Gomes Freitas, Rachel Riera
BACKGROUND: Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus, and more than 75% of patients who have had diabetes for more than 20 years will have some degree of DR. This disease is highly destructive to self-esteem and puts a high burden on public health and pension systems due to the effects that it has on people of working age. The current mainstay of treatment is laser photocoagulation, which causes impairment of vision and discomfort to patients...
February 22, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28225543/cuba-s-aging-and-alzheimer-longitudinal-study
#4
Juan de Jesús Llibre-Rodríguez, Adolfo Valhuerdi-Cepero, Ana M López-Medina, Lisseth Noriega-Fernández, Rutbeskia Porto-Álvarez, Milagros A Guerra-Hernández, Rodolfo I Bosch-Bayard, Tania Zayas-Llerena, Elaine Hernandez-Ulloa, Ana L Rodríguez-Blanco, Enrique Salazar-Pérez, Juan C Llibre-Guerra, Jorge J Llibre-Guerra, Beatriz Marcheco-Teruel
Aging and Alzheimer is a prospective, longitudinal cohort study involving 2944 adults aged ≥65 years from selected areas in Cuba's Havana and Matanzas Provinces. This door-to-door study, which began in 2003, includes periodic assessments of the cohort based on an interview; physical exam; anthropometric measurements; and diagnosis of dementia and its subtypes, other mental disorders, and other chronic non-communicable diseases and their risk factors. Information was gathered on sociodemographic characteristics; disability, dependency and frailty; use of health services; and characteristics of care and caregiver burden...
January 2017: MEDICC Review
https://www.readbyqxmd.com/read/28217505/noncommunicable-disease-in-rural-india-are-we-seriously-underestimating-the-risk-the-nallampatti-noncommunicable-disease-study
#5
Krishnan Swaminathan, Ganesh Veerasekar, Sujatha Kuppusamy, Mohanraj Sundaresan, Ganesan Velmurugan, Nalla G Palaniswami
AIM: To assess the prevalence of noncommunicable diseases in a true rural farming population in South India and compare the data with the landmark contemporary Indian Council of Medical Research-India Diabetes (ICMR-INDIAB) study. METHODS: Local Ethics Committee approval and informed consent was obtained from all participants. Inclusion criteria were participants, aged ≥20 and ≤85 years, from Nallampatti, a classical farming village from Tamil Nadu state, India...
January 2017: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28127468/burden-of-hypertension-in-the-capital-of-afghanistan-a-cross-sectional-study-in-kabul-city-2015
#6
Khwaja Mir Islam Saeed
Background. This study had the objective to assess the prevalence and associated factors of hypertension in an urban setting, Kabul city, Afghanistan. Materials and Methods. The World Health Organization's STEP-wise approach was adopted and used in Kabul in November 2015. The study analyzed a sample of 1172 adults in the age group of 25-70 years. Demographic, socioeconomic, and behavior data were collected using a structured questionnaire. Fasting venous blood sample was collected to assess the lipid profile and fasting blood sugar...
2017: International Journal of Hypertension
https://www.readbyqxmd.com/read/28057507/association-between-thyroid-hormone-parameters-and-dyslipidemia-among-type-2-diabetes-mellitus-patients-comparative-cross-sectional-study
#7
Amare Desalegn Wolide, Belay Zawdie, Tilahun Alemayehu, Samuel Tadesse
BACKGROUND: The relationship between thyroid function and lipid profile has been documented in T2DM and healthy subjects. The aim of the current study was to assess the association between thyroid hormone parameters and dyslipidemia in T2DM and non-diabetic study participants. METHOD AND MATERIALS: In this comparative cross-sectional study, 214 type 2 diabetic and 214 non-diabetic study participants were enrolled. Clinical and anthropometric data were collected from all study participants...
December 26, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28055017/rny-yrna-derived-small-rnas-regulate-cell-death-and-inflammation-in-monocytes-macrophages
#8
Zoheir Hizir, Silvia Bottini, Valerie Grandjean, Michele Trabucchi, Emanuela Repetto
The recent discovery of new classes of small RNAs has opened unknown territories to explore new regulations of physiopathological events. We have recently demonstrated that RNY (or Y RNA)-derived small RNAs (referred to as s-RNYs) are an independent class of clinical biomarkers to detect coronary artery lesions and are associated with atherosclerosis burden. Here, we have studied the role of s-RNYs in human and mouse monocytes/macrophages and have shown that in lipid-laden monocytes/macrophages s-RNY expression is timely correlated to the activation of both NF-κB and caspase 3-dependent cell death pathways...
January 5, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28049433/comparison-of-gene-expression-response-to-neutron-and-x-ray-irradiation-using-mouse-blood
#9
Constantinos G Broustas, Yanping Xu, Andrew D Harken, Guy Garty, Sally A Amundson
BACKGROUND: In the event of an improvised nuclear device detonation, the prompt radiation exposure would consist of photons plus a neutron component that would contribute to the total dose. As neutrons cause more complex and difficult to repair damage to cells that would result in a more severe health burden to affected individuals, it is paramount to be able to estimate the contribution of neutrons to an estimated dose, to provide information for those making treatment decisions. RESULTS: Mice exposed to either 0...
January 3, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28044466/brief-communication-plasma-lipid-oxidation-predicts-atherosclerotic-status-better-than-cholesterol-in-diabetic-apolipoprotein-e-deficient-mice
#10
Karen Ekkelund Petersen, Jens Lykkesfeldt, Kirsten Raun, Günaj Rakipovski
Increased levels of oxidative stress have been suggested to play a detrimental role in the development of diabetes-related vascular complications. Here, we investigated whether the concentration of malondialdehyde, a marker of lipid oxidation correlated to the degree of aortic plaque lesions in a proatherogenic diabetic mouse model. Three groups of apolipoprotein E knockout mice were studied for 20 weeks, a control, a streptozotocin-induced diabetic, and a diabetic enalapril-treated group. Enalapril was hypothesized to lower oxidative stress level and thus the plaque burden...
January 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28011231/metabolic-syndrome-and-occupation-any-association-prevalence-among-auto-technicians-and-school-teachers-in-south-west-nigeria
#11
Adeseye A Akintunde, Taiwo W Oloyede
AIMS: To determine occupational association with metabolic syndrome among auto technicians and school teachers. METHODS: One hundred and sixty six subjects were selected for this study. Clinical data was obtained while laboratory investigations including plasma glucose and lipid profile were performed. Statistical analysis was done with SPSS 20.0. P<0.05 was taken as statistically significant. RESULTS: School teachers had significantly higher mean total cholesterol and LDL-cholesterol compared to auto technicians...
December 14, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28004792/nod2-dependent-neutrophil-recruitment-is-required-for-early-protective-immune-responses-against-infectious-litomosoides-sigmodontis-l3-larvae
#12
Jesuthas Ajendra, Sabine Specht, Sebastian Ziewer, Andrea Schiefer, Kenneth Pfarr, Marijo Parčina, Thomas A Kufer, Achim Hoerauf, Marc P Hübner
Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) recognizes muramyl dipeptide (MDP) of bacterial cell walls, triggering NFκB-induced pro-inflammation. As most human pathogenic filariae contain Wolbachia endobacteria that synthesize the MDP-containing cell wall precursor lipid II, NOD2's role during infection with the rodent filaria Litomosoides sigmodontis was investigated. In NFκB reporter-cells, worm-extract containing Wolbachia induced NOD2 and NOD1. NOD2-deficient mice infected with L...
December 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27998159/relationship-between-cystatin-c-retinol-binding-protein-4-and-framingham-risk-score-in-healthy-postmenopausal-women
#13
Aleksandra Klisic, Jelena Kotur-Stevuljevic, Nebojsa Kavaric, Marija Matic
BACKGROUND: We aimed to examine the relationship between high levels of cystatin C, retinol-binding protein 4 (RBP4) and cardiovascular risk score [determined by Framingham Risk Score (FRS)] in postmenopausal women. METHODS: A total of apparently healthy 129 postmenopausal women (mean age 57.1 ± 4.6 years) were included. Serum cystatin C, RBP4, glucose, lipid parameters, creatinine, uric acid and high sensitivity C-reactive protein (hsCRP) were determined. Anthropometric parameters and blood pressure were also obtained...
December 2016: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/27994108/prevalence-of-and-factors-associated-with-nephropathy-in-diabetic-patients-attending-an-outpatient-clinic-in-harare-zimbabwe
#14
Pasipanodya Ian Machingura, Vasco Chikwasha, Parmenas Nelson Okwanga, Exnevia Gomo
There is limited information on the burden of diabetic nephropathy in developing countries. This study aimed to determine the prevalence of and factors associated with nephropathy among diabetic patients attending an outpatient clinic in Harare, Zimbabwe. In an analytical cross-sectional study, diabetic patients were consecutively enrolled and a questionnaire administered, clinical assessment conducted, and blood samples collected for human immunodeficiency virus testing and measurement of lipids, creatinine, fructosamine, and glycosylated hemoglobin levels...
February 8, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27846215/under-prescribing-of-prevention-drugs-and-primary-prevention-of-stroke-and-transient-ischaemic-attack-in-uk-general-practice-a-retrospective-analysis
#15
Grace M Turner, Melanie Calvert, Max G Feltham, Ronan Ryan, David Fitzmaurice, K K Cheng, Tom Marshall
BACKGROUND: Stroke is a leading cause of death and disability; worldwide it is estimated that 16.9 million people have a first stroke each year. Lipid-lowering, anticoagulant, and antihypertensive drugs can prevent strokes, but may be underused. METHODS AND FINDINGS: We analysed anonymised electronic primary care records from a United Kingdom (UK) primary care database that covers approximately 6% of the UK population. Patients with first-ever stroke/transient ischaemic attack (TIA), ≥18 y, with diagnosis between 1 January 2009 and 31 December 2013, were included...
November 2016: PLoS Medicine
https://www.readbyqxmd.com/read/27806835/determinants-of-carotid-atherosclerotic-plaque-burden-in-a-stroke-free-population
#16
Mariana Selwaness, Reinhard Hameeteman, Ronald Van 't Klooster, Quirijn Van den Bouwhuijsen, Albert Hofman, Oscar H Franco, Wiro J Niessen, Stefan Klein, Meike W Vernooij, Aad Van der Lugt, Jolanda J Wentzel
BACKGROUND AND AIMS: In a large stroke-free population, we sought to identify cardiovascular risk factors and carotid plaque components associated with carotid plaque burden, lumen volume and stenosis. METHODS: The carotid arteries of 1562 stroke-free participants from The Rotterdam Study were imaged on a 1.5-Tesla MRI scanner. Inner and outer wall of the carotid arteries were automatically segmented and lumen volume (mm(3)), wall volume (outer wall-inner wall) and plaque burden (wall volume/outer wall volume) (%) were quantified...
December 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27780336/improving-physical-health-in-patients-with-chronic-mental-disorders-twelve-month-results-from-a-randomized-controlled-collaborative-care-trial
#17
Amy M Kilbourne, Michelle M Barbaresso, Zongshan Lai, Kristina M Nord, Margretta Bramlet, David E Goodrich, Edward P Post, Daniel Almirall, Mark S Bauer
OBJECTIVE: Persons with chronic mental disorders are disproportionately burdened with physical health conditions. We determined whether Life Goals Collaborative Care compared to usual care improves physical health in patients with mental disorders within 12 months. METHODS: This single-blind randomized controlled effectiveness study of a collaborative care model was conducted at a midwestern Veterans Affairs urban outpatient mental health clinic. Patients (N = 293 out of 474 eligible approached) with an ICD-9-CM diagnosis of schizophrenia, bipolar disorder, or major depressive disorder and at least 1 cardiovascular disease risk factor provided informed consent and were randomized (February 24, 2010, to April 29, 2015) to Life Goals (n = 146) or usual care (n = 147)...
January 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27759337/management-practices-in-indian-patients-with-uncontrolled-hypertension
#18
Rajkumar Bharatia, Manoj Chitale, Ganesh Narain Saxena, Raman Ganesh Kumar, Chikkalingaiah, Abhijit Trailokya, Kalpesh Dalvi, Suhas Talele
INTRODUCTION: Hypertension (HTN), being a major risk factor for cardiovascular diseases (CVDs), is an important issue of medical and public health. High blood pressure (BP) is ranked as the third most important risk factor for attributable burden of disease in south Asia (2010). Hypertension (HTN) exerts a substantial public health burden on cardiovascular health status and healthcare systems in India. Uncontrolled hypertension among adults with hypertension is associated with increased mortality...
July 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27754291/br-08-3-management-of-dyslipidemia-in-hypertension
#19
V V Muthusamy
Cardiovascular disease burden is increasing all over the world. The diagnosis of hypertension is considered when a person has persistently elevated BP (Systolic BP more than 140 mmHg and/or Diastolic BP more than 90 mmHg). Dyslipidemia denotes abnormal levels of lipids in the blood (Total Cholesterol >200 mg%, Low density lipoprotein (LDL) >100 mg%, Triglycerides (TGL) >150 mg% and High density lipoprotein (HDL) <40 mg in men and < 50 mg in women. Hypertension and Dyslipidemia constitute the important components of metabolic syndrome as per the definition of NCEP Guidelines-Adult Treatment Panel III (ATP III)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754064/os-16-03-cholesterol-lipids-and-life-style-factors-for-middle-aged-dyslipidemia-middle-age-dyslipidemia-treatment-program-madtp-2015
#20
Rakesh Sharma
OBJECTIVE: ·MADTP 2015 may suggest diet, exercise, behavior and positive attitude to bring normal blood lipid levels in reducing risk of cardiovascular disease among middle aged persons.LONGLIVE LIFESTYLE cholesterol lowering program may reduce risk of cardiovascular disease by diet, six month exercise prescription and modified habits of smoking, alcohol and behavior DESIGN AND METHOD:: LONGLIVE LIFESTYLE diet plan along with walking-running exercise and behavior for six months was tested to improve serum high density lipoprotein cholesterol (HDL-C) appeared earliest; and the improvement of low density lipoprotein IV; cholesterol (LDL-C)...
September 2016: Journal of Hypertension
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