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https://www.readbyqxmd.com/read/27886692/cardiovascular-disease-risk-in-patients-with-rheumatic-diseases
#1
REVIEW
Rachel H Mackey, Lewis H Kuller, Larry W Moreland
Evidence suggests the greater than 1.5 increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA) is related to an accelerated burden of subclinical atherosclerosis that develops before the diagnosis of RA. Dyslipidemia in RA is better quantified by lipoproteins and apolipoproteins than cholesterol levels. Current risk factors likely underestimate CVD risk partly by underestimating prior risk factor levels. To reduce CVD risk in RA, control disease activity and aggressively treat CVD risk factors...
February 2017: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/27857821/carotid-artery-atherosclerosis-in-patients-with-active-rheumatoid-arthritis-predictors-of-plaque-occurrence-and-progression-over-24-weeks
#2
Janet E Pope, Tatiana Nevskaya, Lillian Barra, Grace Parraga
INTRODUCTION: This study evaluated the prevalence and progression of subclinical carotid artery atherosclerosis in active rheumatoid arthritis (RA). METHODS: Carotid arteries of RA patients were scanned using 3D ultrasound at baseline and 24 weeks for total plaque area, vessel wall volume, and intima-media thickness (IMT), as well as arterial stiffness measured using pulse wave velocity. Variables related to inflammation, lipids and cardiovascular (CV) risk were assessed for associations with plaque progression...
2016: Open Rheumatology Journal
https://www.readbyqxmd.com/read/27849287/effects-of-comprehensive-cardiac-rehabilitation-on-functional-capacity-and-cardiovascular-risk-factors-in-brazilians-assisted-by-public-health-care-protocol-for-a-randomized-controlled-trial
#3
Gabriela S S Chaves, Gabriela L M Ghisi, Sherry L Grace, Paul Oh, Antonio L Ribeiro, Raquel R Britto
Background: Cardiovascular Disease (CVD) is the leading burden of disease worldwide. Moreover, CVD-related death rates are considered an epidemic in low- and middle-income countries (LMICs). Research shows that cardiac rehabilitation (CR) participation reduces death and improves disability and quality of life. Given the growing epidemic of CVD in LMICs and the insufficient evidence about CR programs in these countries, a Randomized Control Trial (RCT) in Latin America is warranted. Objective: To investigate the effects of comprehensive CR on functional capacity and cardiovascular risk factors...
October 27, 2016: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/27777902/prevalence-of-dyslipidemia-and-its-association-with-other-coronary-artery-disease-risk-factors-among-urban-population-in-southeast-of-iran-results-of-the-kerman-coronary-artery-disease-risk-factors-study-kercadrs
#4
Hamid Najafipour, Mostafa Shokoohi, Gholamreza Yousefzadeh, Behzad Sarvar Azimzadeh, Gholamreza Moshtaghi Kashanian, Mohamad Mehdi Bagheri, Ali Mirzazadeh
BACKGROUND: Despite the importance of identifying and screening dyslipidemia to prevent coronary artery diseases CAD(Coronary Artery Disease), little information is available on dyslipidemia in our large area. So the present study aimed to assess the management status of lipid abnormalities and its association with other CAD risk factors in an urban population of southeast of Iran. METHODS: This cross-sectional study was a part of the Kerman coronary artery disease risk factor study KERCADRS (Kerman coronary artery disease risk study) as a population-based, epidemiological research among 5900 individuals aged 15 to 75 years who were residents of Kerman city, the largest city in Southeast of Iran...
2016: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/27765771/estimating-the-population-impact-of-lp-a-lowering-on-the-incidence-of-myocardial-infarction-and-aortic-stenosis
#5
Mehdi Afshar, Pia R Kamstrup, Ken Williams, Allan D Sniderman, Børge G Nordestgaard, George Thanassoulis
OBJECTIVE: High lipoprotein(a) (Lp[a]) is the most common genetic dyslipidemia and is a causal factor for myocardial infarction (MI) and aortic stenosis (AS). We sought to estimate the population impact of Lp(a) lowering that could be achieved in primary prevention using the therapies in development. APPROACH AND RESULTS: We used published data from 2 prospective cohorts. High Lp(a) was defined as ≥50 mg/dL (≈20th percentile). Relative risk, attributable risk, the attributable risk percentage, population attributable risk, and the population attributable risk percentage were calculated as measures of the population impact...
October 20, 2016: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/27755393/prescriber-continuity-and-disease-control-of-older-adults
#6
Matthew L Maciejewski, Bradley G Hammill, Elizabeth A Bayliss, Laura Ding, Corrine I Voils, Lesley H Curtis, Virginia Wang
BACKGROUND: Medicare beneficiaries with multiple chronic conditions are typically seen by multiple providers, particularly specialists. Clinically appropriate referrals to multiple specialists may compromise the continuity of care for multiple chronic condition beneficiaries and create care plans that patients may find challenging to reconcile, which may impact patient outcomes. OBJECTIVE: The objective was to examine whether glycemic control or lipid control was associated with the number of prescribers of cardiometabolic medications...
October 14, 2016: Medical Care
https://www.readbyqxmd.com/read/27754291/br-08-3-management-of-dyslipidemia-in-hypertension
#7
V V Muthusamy
Cardiovascular disease burden is increasing all over the world. The diagnosis of hypertension is considered when a person has persistently elevated BP (Systolic BP more than 140 mmHg and/or Diastolic BP more than 90 mmHg). Dyslipidemia denotes abnormal levels of lipids in the blood (Total Cholesterol >200 mg%, Low density lipoprotein (LDL) >100 mg%, Triglycerides (TGL) >150 mg% and High density lipoprotein (HDL) <40 mg in men and < 50 mg in women. Hypertension and Dyslipidemia constitute the important components of metabolic syndrome as per the definition of NCEP Guidelines-Adult Treatment Panel III (ATP III)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754064/os-16-03-cholesterol-lipids-and-life-style-factors-for-middle-aged-dyslipidemia-middle-age-dyslipidemia-treatment-program-madtp-2015
#8
Rakesh Sharma
OBJECTIVE: ·MADTP 2015 may suggest diet, exercise, behavior and positive attitude to bring normal blood lipid levels in reducing risk of cardiovascular disease among middle aged persons.LONGLIVE LIFESTYLE cholesterol lowering program may reduce risk of cardiovascular disease by diet, six month exercise prescription and modified habits of smoking, alcohol and behavior DESIGN AND METHOD:: LONGLIVE LIFESTYLE diet plan along with walking-running exercise and behavior for six months was tested to improve serum high density lipoprotein cholesterol (HDL-C) appeared earliest; and the improvement of low density lipoprotein IV; cholesterol (LDL-C)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27706020/berry-fruit-consumption-and-metabolic-syndrome
#9
Stefano Vendrame, Cristian Del Bo', Salvatore Ciappellano, Patrizia Riso, Dorothy Klimis-Zacas
Metabolic Syndrome is a cluster of risk factors which often includes central obesity, dyslipidemia, insulin resistance, glucose intolerance, hypertension, endothelial dysfunction, as well as a pro-inflammatory, pro-oxidant, and pro-thrombotic environment. This leads to a dramatically increased risk of developing type II diabetes mellitus and cardiovascular disease, which is the leading cause of death both in the United States and worldwide. Increasing evidence suggests that berry fruit consumption has a significant potential in the prevention and treatment of most risk factors associated with Metabolic Syndrome and its cardiovascular complications in the human population...
September 30, 2016: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/27702726/obesity-non-communicable-disease-ncd-risk-factors-and-dietary-factors-among-chinese-school-aged-children
#10
Carmen Piernas, Dantong Wang, Shufa Du, Bing Zhang, Zhihong Wang, Chang Su, Barry M Popkin
BACKGROUND AND OBJECTIVES: China's nutrition transition is characterized by dramatic increases in overweight and cardiometabolic (CM) risk. The burden of obesity, CM risk factors and dietary intake among Chinese children were explored. METHODS AND STUDY DESIGN: Children 7-12 y old from the 2009 China Health and Nutrition Survey with available dietary intake data, anthropometry, blood pressure, and fasting blood samples were included (n=663). CM risk prevalence was calculated; logistic regression was used to investigate the association of nutrient intakes with CM risk, adjusting for age, gender, physical activity, area of residence and income...
December 2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27666599/prevalence-and-distribution-of-coronary-artery-calcification-in-asymptomatic-united-states-and-korean-adults%C3%A3-cross-sectional-propensity-matched-analysis
#11
Donghee Han, Bríain Ó Hartaigh, Heidi Gransar, Ji Hyun Lee, Su-Yeon Choi, Eun Ju Chun, Jidong Sung, Hae-Won Han, Sung Hak Park, Tracy Callister, Fay Y Lin, James K Min, Hyuk-Jae Chang
BACKGROUND: The incidence of coronary artery disease (CAD) varies depending on ethnicity, but the precise differences remain to be firmly established. This study therefore evaluated the disparity in coronary artery calcification (CAC), as a marker of CAD, in asymptomatic US and Korean adults.Methods and Results:CAC score was compared between asymptomatic Korean (n=15,128) and US (n=7,533) adults. Propensity score matching was performed according to age, gender, hypertension, diabetes, dyslipidemia, and current smoking, which generated 2 cohorts of 5,427 matched pairs...
September 21, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/27663800/cardiovascular-diseases-in-patients-with-bipolar-disease-pragmatic-management
#12
Cátia Jesus, Inês Jesus, Mark Agius
BACKGROUND: Bipolar disorder (BD), also known as manic-depressive illness, is a condition characterized by unusual shifts in mood, energy, activity levels, and the ability to carry out day-to-day tasks. Bipolar disorder is known to be a chronic and disabling disease associated with higher incidence of obesity, diabetes, metabolic syndrome, dyslipidemias, hypertension and tobacco use which all together are known risk factors for the development of Cardiovascular diseases. With this research we wish to collect evidence to show how Cardiovascular diseases (CVD) affect Patients with Bipolar disease, the burden it can have in patients lives, to understand how this problem has been assessed so far and present suggestions that may improve the health care of these patients...
September 2016: Psychiatria Danubina
https://www.readbyqxmd.com/read/27643289/br-08-3-management-of-dyslipidemia-in-hypertension
#13
V V Muthusamy
Cardiovascular disease burden is increasing all over the world. The diagnosis of hypertension is considered when a person has persistently elevated BP (Systolic BP more than 140 mmHg and/or Diastolic BP more than 90 mmHg). Dyslipidemia denotes abnormal levels of lipids in the blood (Total Cholesterol >200 mg%, Low density lipoprotein (LDL) >100 mg%, Triglycerides (TGL) >150 mg% and High density lipoprotein (HDL) <40 mg in men and < 50 mg in women. Hypertension and Dyslipidemia constitute the important components of metabolic syndrome as per the definition of NCEP Guidelines-Adult Treatment Panel III (ATP III)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642984/os-16-03-cholesterol-lipids-and-life-style-factors-for-middle-aged-dyslipidemia-middle-age-dyslipidemia-treatment-program-madtp-2015
#14
Rakesh Sharma
OBJECTIVE: ·MADTP 2015 may suggest diet, exercise, behavior and positive attitude to bring normal blood lipid levels in reducing risk of cardiovascular disease among middle aged persons.LONGLIVE LIFESTYLE cholesterol lowering program may reduce risk of cardiovascular disease by diet, six month exercise prescription and modified habits of smoking, alcohol and behavior DESIGN AND METHOD: : LONGLIVE LIFESTYLE diet plan along with walking-running exercise and behavior for six months was tested to improve serum high density lipoprotein cholesterol (HDL-C) appeared earliest; and the improvement of low density lipoprotein IV; cholesterol (LDL-C)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27619923/cardiovascular-consequences-of-childhood-secondhand-tobacco-smoke-exposure-prevailing-evidence-burden-and-racial-and-socioeconomic-disparities-a-scientific-statement-from-the-american-heart-association
#15
Geetha Raghuveer, David A White, Laura L Hayman, Jessica G Woo, Juan Villafane, David Celermajer, Kenneth D Ward, Sarah D de Ferranti, Justin Zachariah
BACKGROUND: Although public health programs have led to a substantial decrease in the prevalence of tobacco smoking, the adverse health effects of tobacco smoke exposure are by no means a thing of the past. In the United States, 4 of 10 school-aged children and 1 of 3 adolescents are involuntarily exposed to secondhand tobacco smoke (SHS), with children of minority ethnic backgrounds and those living in low-socioeconomic-status households being disproportionately affected (68% and 43%, respectively)...
October 18, 2016: Circulation
https://www.readbyqxmd.com/read/27613744/why-is-apolipoprotein-ciii-emerging-as-a-novel-therapeutic-target-to-reduce-the-burden-of-cardiovascular-disease
#16
REVIEW
Marja-Riitta Taskinen, Jan Borén
ApoC-III was discovered almost 50 years ago, but for many years, it did not attract much attention. However, as epidemiological and Mendelian randomization studies have associated apoC-III with low levels of triglycerides and decreased incidence of cardiovascular disease (CVD), it has emerged as a novel and potentially powerful therapeutic approach to managing dyslipidemia and CVD risk. The atherogenicity of apoC-III has been attributed to both direct lipoprotein lipase-mediated mechanisms and indirect mechanisms, such as promoting secretion of triglyceride-rich lipoproteins (TRLs), provoking proinflammatory responses in vascular cells and impairing LPL-independent hepatic clearance of TRL remnants...
October 2016: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/27595388/burden-and-risk-factors-of-dyslipidemia-results-from-a-steps-survey-in-punjab-india
#17
Jaya Prasad Tripathy, J S Thakur, Gursimer Jeet, Sohan Chawla, Sanjay Jain, Arnab Pal, Rajendra Prasad
AIMS: Raised blood cholesterol is an important risk factor for heart disease and stroke. Globally, one third of ischaemic heart disease is attributable to high cholesterol. This article reports prevalence of dyslipidemia in the North Indian state of Punjab as part of a large household Non Communicable Disease (NCD) Risk Factor Survey. MATERIALS AND METHODS: A household NCD STEPS survey was done in the state of Punjab, India in a multistage stratified sample of 5127 individuals...
August 23, 2016: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/27584973/renal-function-and-attributable-risk-of-death-and-cardiovascular-hospitalization-in-patients-with-cardiovascular-risk-factors-from-a-registry-based-cohort-the-estudio-cardiovascular-valencia-risk-study
#18
Maria Tellez-Plaza, Domingo Orozco-Beltran, Vicente Gil-Guillen, Salvador Pita-Fernandez, Jorge Navarro-Pérez, Vicente Pallares, Francisco Valls, Antonio Fernandez, Ana María Perez-Navarro, Carlos Sanchis, Alejandro Dominguez-Lucas, Jose M Martin-Moreno, Josep Redon
BACKGROUND: Information about the attributable risk associated with renal dysfunction in patients with cardiovascular risk factors is lacking. OBJECTIVE: We aimed to estimate the attributable risk associated with chronic kidney disease Epidemiology Collaboration-estimated glomerular filtration rate (eGFR), for all-cause mortality, and cardiovascular hospitalization. DESIGN, SETTING, AND PARTICIPANTS: Prospective study of study participants with cardiovascular risk factors in 2008-2012...
November 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27574399/efficacy-and-safety-of-fixed-dose-combination-therapy-with-olmesartan-medoxomil-and-rosuvastatin-in-korean-patients-with-mild-to-moderate-hypertension-and-dyslipidemia-an-8-week-multicenter-randomized-double-blind-factorial-design-study-olsta-d-rct-olmesartan
#19
Jin-Sun Park, Joon-Han Shin, Taek-Jong Hong, Hong-Seog Seo, Wan-Joo Shim, Sang-Hong Baek, Jin-Ok Jeong, Youngkeun Ahn, Woong-Chol Kang, Young-Hak Kim, Sang-Hyun Kim, Min-Su Hyon, Dong-Hoon Choi, Chang-Wook Nam, Tae-Ho Park, Sang-Chol Lee, Hyo-Soo Kim
The pill burden of patients with hypertension and dyslipidemia can result in poor medication compliance. This study aimed to evaluate the efficacy and safety of fixed-dose combination (FDC) therapy with olmesartan medoxomil (40 mg) and rosuvastatin (20 mg) in Korean patients with mild to moderate hypertension and dyslipidemia. This multicenter, randomized, double-blind, factorial-design study included patients aged ≥20 years with mild to moderate essential hypertension and dyslipidemia. Patients were randomly assigned to receive FDC therapy (40 mg olmesartan medoxomil, 20 mg rosuvastatin), 40 mg olmesartan medoxomil, 20 mg rosuvastatin, or a placebo...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27570971/age-related-changes-in-the-cardiometabolic-profiles-in-singapore-resident-adult-population-findings-from-the-national-health-survey-2010
#20
Tze Ping Loh, Stefan Ma, Derrick Heng, Chin Meng Khoo
We describe the centile trends of the blood pressure, glycemia and lipid profiles as well as renal function of a representative population who participated in the Singapore National Health Survey in 2010. Representative survey population was sampled in two phases, first using geographical/ residential dwelling type stratification, followed up ethnicity. 2,407 survey participants without any self-reported medical or medication history for diabetes mellitus, hypertension and dyslipidemia were included in this analysis...
2016: PloS One
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