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https://www.readbyqxmd.com/read/28711335/echocardiographic-reference-ranges-in-older-children-and-adolescents-in-sub-saharan-africa
#1
Edith D Majonga, Andrea M Rehman, Grace McHugh, Hilda A Mujuru, Kusum Nathoo, Mohammad S Patel, Shungu Munyati, Jon O Odland, Katharina Kranzer, Juan P Kaski, Rashida A Ferrand
BACKGROUND: Echocardiographic reference ranges are important to identify abnormalities of cardiac dimensions. Reference ranges for children in sub-Saharan Africa have not been established. The aim of this study was to establish echocardiographic z-score references for Black children in sub-Saharan Africa. METHODS: 282 healthy subjects aged 6-16years (143 [51%] males) with no known history of cardiac disease were enrolled in the study in Harare, Zimbabwe between 2014 and 2016...
June 30, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28702739/value-of-the-neutrophil-to-lymphocyte-ratio-in-predicting-left-ventricular-recovery-in-patients-with-peripartum-cardiomyopathy
#2
Ufuk Gürkan, Haldun Akgöz, Şukru Aksoy, Özlem Can Gürkan, Altug Osken, Sennur Unal Dayi, Dilaver Oz, Recep Haci
OBJECTIVE: The aim of this study was to assess the value of the neutrophil-to-lymphocyte ratio (NLR) in predicting left ventricular (LV) recovery in patients with peripartum cardiomyopathy (PPCM). METHODS: Patients with PPCM (n = 40), who were admitted to our tertiary reference hospital between 2007 and 2015 were retrospectively analyzed. All patients were followed-up for at least 12 months after the diagnosis. All patients had standard echocardiographic examination at baseline and the last follow-up visit...
July 12, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28692307/association-of-the-344t-c-polymorphism-in-aldosterone-synthase-gene-promoter-with-left-ventricular-structure-in-chinese-han-a-meta-analysis
#3
Chengqian Yin, Wei Gu, Yun Gao, Zhao Li, Xuanzu Chen, Zhizhong Li, Shaojun Wen
No consensus view has been published on the relationship between the aldosterone synthase gene (CYP11B2) -344C/T polymorphism and left ventricular hypertrophy (LVH) in Chinese Han. We undertook a meta-analysis to investigate the potential association of this polymorphism and left ventricular structure-related phenotypes, including left ventricular mass (LVM), left ventricular mass index (LVMI), left ventricular end systolic diameter (LVESD), left ventricular end diastolic dimension (LVEDD), left ventricular posterior wall thickness (LVPWT), and interventricular septal wall thickness (IVS)...
July 10, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28673775/intramyocardial-bone-marrow-mononuclear-cells-versus-bone-marrow-derived-and-adipose-mesenchymal-cells-in-a-rat-model-of-dilated-cardiomyopathy
#4
M Dolores Carmona, Sagrario Cañadillas, Miguel Romero, Alfonso Blanco, Sonia Nogueras, Concha Herrera
BACKGROUND: Effects of cell therapy on dilated cardiomyopathy (DCM) have been investigated in pre-clinical models using distinct cellular types in each study. A single study that compares the effectiveness of different cells is lacking. METHODS: We have compared the effects of intramyocardial injection (IMI) of bone marrow (BM)-derived mononuclear cells (MNCs), BM and adipose tissue (AT) mesenchymal stromal cells (BM-MSCs and AT-MSCs) on heart function, histological changes and myocardial ultrastructure in a rat model of DCM...
June 30, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28670776/myocardial-protective-effect-of-antegrade-cardioplegic-cardiac-arrest-versus-ventricular-fibrillation-during-cardiopulmonary-bypass-on-immediate-postoperative-and-mid-term-left-ventricular-function-in-right-ventricular-outflow-tract-surgery
#5
Sang Yoon Kim, Sungkyu Cho, Ji-Hyun Lee, Jin-Tae Kim, Woong-Han Kim
The objective of this study is to examine the myocardial protective effect of antegrade cardioplegic cardiac arrest (ACC) versus ventricular fibrillation (VF) on short-term and mid-term left ventricular (LV) function in right ventricular outflow tract (RVOT) surgery. RVOT operations conducted from January 2006 to December 2015 were reviewed. The numbers of cases using ACC and VF were 71 and 49, respectively. Postoperative mortality and morbidity were compared between the two groups. Before and after propensity score matching, left ventricular ejection fraction (LVEF) and left ventricular end-systolic/end-diastolic diameter (LVESD/LVEDD) in echocardiography were measured immediately after operation and at mid-term follow-up between postoperative 6 and 24 months...
July 2, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28663046/long-term-vagal-stimulation-for-heart-failure-eighteen-month-results-from-the-neural-cardiac-therapy-for-heart-failure-nectar-hf-trial
#6
Gaetano M De Ferrari, Craig Stolen, Anton E Tuinenburg, D Jay Wright, Josep Brugada, Christian Butter, Helmut Klein, Petr Neuzil, Cornelis Botman, Maria Angeles Castel, Antonio D'Onofrio, Gert J de Borst, Scott Solomon, Kenneth M Stein, Bernd Schubert, Kevin Stalsberg, Nicholas Wold, Stephen Ruble, Faiez Zannad
BACKGROUND: The NECTAR-HF study evaluated safety and feasibility of vagal nerve stimulation (VNS) for the treatment of heart failure patients. The first six-month randomized phase of the study did not show improvement in left ventricular remodelling in response to VNS. This study reports the 18-month results and provides novel findings aiming to understand the lack of efficacy of VNS, including a new technique assessing the effects of VNS. METHODS: Ninety-six patients were randomized 2:1 to active or inactive VNS for 6months, thereafter VNS was activated for all patients...
June 10, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28625246/-effects-of-high-flow-hemodialysis-on-the-biomarker-of-myocardium-injury-and-the-cardiac-function-related-records-in-uremia-patients
#7
Ling Tang, Xiaofeng Deng, Qing Dai, Hengfen Xiao, Yue Shu, Min Jiang, Ling Wei, Li Wang
OBJECTIVE: To investigate the effects of high flow hemodialysis (HFHD) on cardiac function in uremia patients. METHODS: A prospective randomized controlled study was conducted. Sixty patients who were diagnosed with uremia, taken maintenance hemodialysis (MHD) and 30 healthy controls admitted to the Second People's Hospital of Guiyang from December 2014 to June 2015 were enrolled. They were randomly divided into two groups: HFHD group (HFHD three times a week) and the routine hemodialysis group (HD group, HD three times a week), with 30 in each group...
June 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28616920/-association-of-gh-and-igf-1-burden-with-cardiac-structural-and-functional-changes-in-acromegaly-patients
#8
Shuo Zhang, Yi-Lin Li, Xiao-Peng Guo, Lu Gao, Yong Yao, Ren-Zhi Wang, Bing Xing
OBJECTIVES: To investigate the association of growth hormone (GH) and insulin-like growth factor (IGF-1) burden with the cardiac structural and functional changes in acromegaly patients. METHODS: Ninety-nine acromegaly patients were enrolled in this study. According to the normal range of echocardiographic parameters of Peking Union Medical College Hospital, the patients were divided into parameter normal group and abnormal group. Correlation analyses were conducted between duration of disease, mean GH, mean IGF-1, GH burden, IGF-1 burden and echocardiography data retrospectively...
May 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28545821/surgical-management-of-severe-ischaemic-mitral-regurgitation
#9
Yong Zhang, Dongxu Wang, Yu Liu, Dengshun Tao, Yan Jin, Hui Jiang, Zengwei Wang, Huishan Wang
BACKGROUND: Coronary artery bypass graft surgery (CABG) with mitral valve surgery is undisputed in severe ischaemic mitral regurgitation (IMR) treatment, but the controversy is whether mitral valve replacement (MVR) or mitral valvuloplasty (MVP) should be used. METHODS: Data was collected from 130 cases of severe IMR patients who underwent CABG and MVP or MVR from June 2010 to June 2015 to compare the short-term efficacy of CABG with MVP or MVR in the treatment of severe IMR patients...
May 9, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28514327/postoperative-assessment-of-myocardial-function-and-microcirculation-in-patients-with-acute-coronary-syndrome-by-myocardial-contrast-echocardiography
#10
Li Jiang, Hong Yao, Zhao-Guang Liang
BACKGROUND Postoperative myocardial function and microcirculation of acute coronary syndrome (ACS) was assessed by myocardial contrast echocardiography (MCE). MATERIAL AND METHODS Eighty-nine ACS patients treated with percutaneous coronary intervention (PCI) were detected by MCE and two-dimensional ultrasonography before and a month later after PCI respectively. Their myocardial perfusion was evaluated by myocardial contrast score (MSC) and contrast score index (CSI); cross-sectional area of microvessel (A), average myocardial microvascular impairment (β), and myocardial blood flow (MBF) were analyzed by cardiac ultrasound quantitative analysis (CUSQ), and fractional flow reserve (FFR) change was observed...
May 17, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28497060/efficacy-and-safety-of-l-carnitine-treatment-for-chronic-heart-failure-a-meta-analysis-of-randomized-controlled-trials
#11
REVIEW
Xiaolong Song, Huiyan Qu, Zongguo Yang, Jingfeng Rong, Wan Cai, Hua Zhou
Background. Whether additional benefit can be achieved with the use of L-carnitine (L-C) in patients with chronic heart failure (CHF) remains controversial. We therefore performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of L-C treatment in CHF patients. Methods. Pubmed, Ovid Embase, Web of Science, and Cochrane Library databases, Chinese National Knowledge Infrastructure (CNKI) database, Wanfang database, Chinese Biomedical (CBM) database, and Chinese Science and Technology Periodicals database (VIP) until September 30, 2016, were identified...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28481959/trpv2-knockout-mice-demonstrate-an-improved-cardiac-performance-following-myocardial-infarction-due-to-attenuated-activity-of-peri-infarct-macrophages
#12
Michal Entin-Meer, Lena Cohen, Einat Hertzberg-Bigelman, Ran Levy, Jeremy Ben-Shoshan, Gad Keren
BACKGROUND: We have recently shown that the expression of the transient receptor potential vanilloid 2 channel, TRPV2, is upregulated in the peri-infarct zone 3-5 days following an acute myocardial infarction (AMI). Further analysis has demonstrated that invading monocytes maturing to macrophages merely harbor the documented elevated expression of this channel. PURPOSE: Assess cardiac function in TRPV2-KO mice compared to TRPV2-WT following AMI and analyze the potential involvement of TRPV2-expressing macrophages in the recovery process...
2017: PloS One
https://www.readbyqxmd.com/read/28410640/florida-sleeve-procedure-is-durable-and-improves-aortic-valve-function-in-marfan-syndrome-patients
#13
Seyed Hossein Aalaei-Andabili, Tomas Martin, Philip Hess, Charles Klodell, Ashkan Karimi, George Arnaoutakis, Teng Lee, Thomas Beaver
BACKGROUND: The Florida sleeve (FS) procedure was developed as a simplified approach for repair of functional type I aortic insufficiency secondary to aortic root aneurysm. We evaluated postoperative aortic valve function, long-term survival, and freedom from reoperation in Marfan syndrome patients who underwent the FS procedure at our center. METHODS: All Marfan syndrome patients undergoing FS procedure from May 2002 to December 2014 were included. Echocardiography assessment included left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), ejection fraction, and degree of aortic insufficiency (none = 0, minimal = 1, mild = 2, moderate = 3, severe = 4)...
April 12, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28365092/cardiac-injury-after-convulsive-status-epilepticus-in-children
#14
Doaa El Amrousy, Maher Abd El-Hafez, Mohamed Nashat, Hossam Hodeib
OBJECTIVE: Convulsive status epilepticus (CSE) is a medical emergency with high mortality that usually occurs within 30 days following the seizure activity. One of the potential mechanisms contributing to mortality in this period following CSE is cardiac injury. The aim of the present study was to evaluate cardiac injury after CSE in children. PATIENTS AND METHODS: Sixty children presented with CSE were enrolled in this study. Thirty healthy children with matched age and sex were taken as a control...
July 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/28290171/effects-of-surgical-techniques-on-long-term-results-in-patients-with-degenerative-mitral-valve-bileaflet-prolapse
#15
Giuseppe Petrone, Renato Bellitti, Clemente Pascarella, Gianantonio Nappi, Giuseppe Signoriello, Pasquale Santé
BACKGROUND: The study aim was to evaluate the long-term results in patients with degenerative mitral valve bileaflet prolapse (DMVBLP) undergoing mitral valve repair (MVr) or mitral valve replacement (MVR), and to compare the consequences of survival related to each technique. METHODS: Between 2001 and 2012, a total of 421 patients underwent isolated primary surgery for DMVBLP. MVr was performed in 146 patients (34.7%), and MVR in 275 (65.3%). MVR patients were allocated to two subgroups...
November 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28238235/prevalence-and-impact-of-prosthesis-patient-mismatch-following-surgical-aortic-valve-replacement-for-pure-aortic-regurgitation
#16
Vincent Auffret, Pierre Voisine, Alexandre Cinq-Mars, Éric Charbonneau, Florent Le Ven, Sacha-Michelle Dubois-Sénéchal, Eduardo Brenna, François Dagenais, Michelle Dubois, Carine Ridard, Mario Sénéchal
BACKGROUND: Prosthesis-patient mismatch (PPM) is highly prevalent among patients undergoing aortic valve replacement (AVR) to treat aortic stenosis. Data regarding the prevalence and impact of PPM on left ventricular remodeling and outcomes in patients who have undergone surgical AVR to treat pure severe aortic regurgitation (AR) are, however, scarce. METHODS: A retrospective analysis was conducted of clinical and echocardiographic data acquired from 50 consecutive patients with pure severe AR, without evidence of significant coronary artery disease, who underwent AVR between 2004 and 2010 at the authors' institution...
September 2016: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28212603/effects-of-renal-denervation-on-cardiac-oxidative-stress-and-local-activity-of-the-sympathetic-nervous-system-and-renin-angiotensin-system-in-acute-myocardial-infracted-dogs
#17
Qiaoli Feng, Chengzhi Lu, Li Wang, Lijun Song, Chao Li, Ravi Chandra Uppada
BACKGROUND: This study sought to evaluate the therapeutic effects of renal denervation (RDN) on acute myocardial infarction (MI) in canines and explore its possible mechanisms of action. METHODS: Eighteen healthy mongrel dogs were randomly assigned to either the control group, the MI group or the MI + RDN group. To assess cardiac function, left ventricular ejection fraction (LVEF), left ventricular end-diastolic dimension (LVEDD), left ventricular end-systolic dimension (LVESD) and fraction shortening (FS) were recorded...
February 17, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28073832/reperfusion-therapy-with-recombinant-human-relaxin-2-serelaxin-attenuates-myocardial-infarct-size-and-nlrp3-inflammasome-following-ischemia-reperfusion-injury-via-enos-dependent-mechanism
#18
Juan Valle Raleigh, Adolfo G Mauro, Teja Devarakonda, Carlo Marchetti, Jun He, Erica Kim, Scott Filippone, Anindita Das, Stefano Toldo, Antonio Abbate, Fadi N Salloum
Aims: The preconditioning-like infarct-sparing and anti-inflammatory effects of the peptide hormone relaxin following ischemic injury have been studied in the heart. Whether reperfusion therapy with recombinant human relaxin-2, serelaxin, reduces myocardial infarct size and attenuates the subsequent NLRP3 inflammasome activation leading to further loss of functional myocardium following ischemia/reperfusion (I/R) injury is unknown. Methods and results: After baseline echocardiography, adult male wild-type C57BL or eNOS knockout mice underwent myocardial infarction (MI) by coronary artery ligation for 30 min followed by 24 h reperfusion...
May 1, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28040769/evidence-of-subannular-and-left-ventricular-morphological-differences-in-patients-with-bicuspid-versus-tricuspid-aortic-valve-stenosis-magnetic-resonance-imaging-based-analysis
#19
Kushtrim Disha, Georg Dubslaff, Mina Rouman, Beatrix Fey, Michael A Borger, Alex J Barker, Thomas Kuntze, Evaldas Girdauskas
Objectives: Prospective analysis of left ventricular (LV) morphological/functional parameters in patients with bicuspid versus tricuspid aortic valve (TAV) stenosis undergoing aortic valve replacement (AVR) surgery. Methods: A total of 190 consecutive patients with BAV ( n  = 154) and TAV stenosis ( n  = 36) (mean age 61 ± 8 years, 65% male) underwent AVR ± concomitant aortic surgery from January 2012 through May 2015. All patients underwent preoperative cardiac magnetic resonance imaging in order to evaluate: (i) left ventricular outflow tract (LVOT) dimensions, (ii) length of anterior mitral leaflet (AML), (iii) end-systolic and end-diastolic LV wall thickness, (iv) LV area, (v) LV end-systolic and end-diastolic diameters (LVESD, LVEDD), (vi) LV end-diastolic and end-systolic volumes (LVEDV, LVESV) and (vii) maximal diameter of aortic root...
March 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27882150/effect-of-stromal-cell-derived-factor-1-on-myocardial-apoptosis-and-cardiac-function-recovery-in-rats-with-acute-myocardial-infarction
#20
Yuanyuan Liu, Songtao Gao, Zheng Wang, Yan Yang, Hong Huo, Xuefeng Tian
The aim of the study was to investigate the effect of stromal cell-derived factor-1 (SDF-1) on myocardial apoptosis and cardiac function recovery in rats with acute myocardial infarction (AMI) and the mechanism of the Toll-like receptor (TLR)-4/nuclear factor-κB (NF-κB) signaling pathway. A total of 64 healthy male F344 rats were randomly divided into the sham operation, model, SDF-1 intervention and SDF-1 antibody groups, with 16 rats in each group. The method of Olivette was used to establish the AMI model by ligation of the left anterior descending artery...
November 2016: Experimental and Therapeutic Medicine
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