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https://www.readbyqxmd.com/read/28088765/allo-allo-triploid-sphagnum-%C3%A3-falcatulum-single-individuals-contain-most-of-the-holantarctic-diversity-for-ancestrally-indicative-markers
#1
Eric F Karlin, Peter E Smouse
BACKGROUND AND AIMS: Allopolyploids exhibit both different levels and different patterns of genetic variation than are typical of diploids. However, scant attention has been given to the partitioning of allelic information and diversity in allopolyploids, particularly that among homeologous monoploid components of the hologenome. Sphagnum × falcatulum is a double allopolyploid peat moss that spans a considerable portion of the Holantarctic. With monoploid genomes from three ancestral species, this organism exhibits a complex evolutionary history involving serial inter-subgeneric allopolyploidizations...
January 14, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28088648/the-influence-of-5-httlpr-transporter-genotype-on-amygdala-subgenual-anterior-cingulate-cortex-connectivity-in-autism-spectrum-disorder
#2
Francisco Velasquez, Jillian Lee Wiggins, Whitney I Mattson, Donna M Martin, Catherine Lord, Christopher S Monk
Social deficits in autism spectrum disorder (ASD) are linked to amygdala functioning and functional connection between the amygdala and subgenual anterior cingulate cortex (sACC) is involved in the modulation of amygdala activity. Impairments in behavioral symptoms and amygdala activation and connectivity with the sACC seem to vary by serotonin transporter-linked polymorphic region (5-HTTLPR) variant genotype in diverse populations. The current preliminary investigation examines whether amygdala-sACC connectivity differs by 5-HTTLPR genotype and relates to social functioning in ASD...
December 23, 2016: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28088558/the-effects-of-upper-body-exercise-across-different-levels-of-blood-flow-restriction-on-arterial-occlusion-pressure-and-perceptual-responses
#3
Kevin T Mattocks, Matthew B Jessee, Brittany R Counts, Samuel L Buckner, J Grant Mouser, Scott J Dankel, Gilberto C Laurentino, Jeremy P Loenneke
Recent studies have investigated relative pressures that are applied during blood flow restriction exercise ranging from 40%-90% of resting arterial occlusion pressure; however, no studies have investigated relative pressures below 40% arterial occlusion pressure. The purpose of this study was to characterize the cardiovascular and perceptual responses to different levels of pressures. Twenty-six resistance trained participants performed four sets of unilateral elbow flexion exercise using 30% of their 1RM in combination with blood flow restriction inflated to one of six relative applied pressures (0%, 10%, 20%, 30%, 50%, 90% arterial occlusion pressure)...
January 11, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28088551/individual-and-sex-differences-in-high-and-low-responder-phenotypes
#4
María B Carreira, Ricardo Cossio, Gabrielle B Britton
Individual differences in responses to a novel environment are an important tool to predict predisposition to neuropsychiatric disorders. One way to examine individual differences involves classifying animals based on locomotion in a novel context. In this study we focused on individual and sex differences by categorizing female and male mice as high (HR) or low responders (LR) on the basis of open field locomotion. We then assessed whether groups differed on behavioral measures of spontaneous alternations, anxiety, depression and contextual fear conditioning...
January 11, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28088502/the-nucleotide-changes-within-hbv-core-promoter-precore-during-the-first-12weeks-of-nucleos-t-ide-treatment-might-be-associated-with-a-better-virological-response
#5
Yaqin Peng, Yutang Li, Jinlin Hou, Jian Sun, Mingze Su, Yao Li, Kuanhui Xiang, Ling Yan, Hui Zhuang, Tong Li
OBJECTIVES: We aimed to study the dynamic changes of hepatitis B virus (HBV) core promoter/precore (CP/preC) sequences during antiviral treatment and their associations with virological responses. MATERIALS AND METHODS: The baseline and 12-week CP/preC sequences (nts 1655-2014) were obtained from 52 chronic hepatitis B patients with positive hepatitis B e antigen (HBeAg), who received a 104-week lamivudine and adefovir dipivoxil combination therapy. The mutations within the CP/preC were analyzed against genotype specific reference sequences...
January 11, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28088408/the-effects-of-adding-fat-to-diets-of-lactating-dairy-cows-on-total-tract-neutral-detergent-fiber-digestibility-a-meta-analysis
#6
K A Weld, L E Armentano
The objective of this meta-analysis was to determine the effects of supplemental fat on fiber digestibility in lactating dairy cattle. Published papers that evaluated the effects of adding fat to the diets of lactating dairy cattle on total-tract neutral detergent fiber digestibility (ttNDFd) and dry matter intake (DMI) were compiled. The final data set included 108 fat-supplemented treatment means, not including low-fat controls, from 38 publications. The fat-supplemented treatment means exhibited a wide range of ttNDFd (49...
January 11, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28088380/aquatic-exercise-therapy-for-people-with-parkinson-s-disease-a-randomized-controlled-trial
#7
Louise M Carroll, Daniele Volpe, Meg E Morris, Jean Saunders, Amanda M Clifford
OBJECTIVE: To evaluate the effects of aquatic exercise therapy on gait variability and disability compared to usual care for people with Parkinson's disease (PD). DESIGN: Single-blind randomized control trial (RCT). SETTING: A community based hydrotherapy pool in Ireland. PARTICIPANTS: Twenty one individuals with PD (Hoehn-Yahr Stages I-III). INTERVENTIONS: Participants were randomly assigned to either an aquatic exercise therapy group (45 minutes, twice a week for 6 weeks) or a control group that received usual care...
January 11, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28088357/joint-genome-wide-prediction-in-several-populations-accounting-for-randomness-of-genotypes-a-hierarchical-bayes-approach-ii-multivariate-spike-and-slab-priors-for-marker-effects-and-derivation-of-approximate-bayes-and-fractional-bayes-factors-for-the-complete
#8
Carlos Alberto Martínez, Kshitij Khare, Arunava Banerjee, Mauricio A Elzo
This study corresponds to the second part of a companion paper devoted to the development of Bayesian multiple regression models accounting for randomness of genotypes in across population genome-wide prediction. This family of models considers heterogeneous and correlated marker effects and allelic frequencies across populations, and has the ability of considering records from non-genotyped individuals and individuals with missing genotypes in any subset of loci without the need for previous imputation, taking into account uncertainty about imputed genotypes...
January 11, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28088355/kir-genes-and-hla-class-i-ligands-in-a-caucasian-brazilian-population-with-colorectal-cancer
#9
Pâmela Portela, Joice Merzoni, Juliana D Lindenau, Daniel C Damin, Timothy John Wilson, Rafael Roesler, Gilberto Schwartsmann, Luiz Mariana Fernando Jobim Jobim
Colorectal cancer (CRC) can occur anywhere in the colon or rectum and represents the third most common cancer in the world in both sexes. Natural killer cells (NK) are part of the innate immune system recognizing class I HLA molecules on target cells through their membrane receptors, called killer cell immunoglobulin-like receptors (KIR). The aim of our study was to evaluate the association between the KIR genes and HLA ligands in patients with colorectal cancer and healthy controls. We examined the polymorphism of 16 KIR genes and their HLA ligands in 154 caucasoid CRC patients and 216 controls...
January 11, 2017: Human Immunology
https://www.readbyqxmd.com/read/28088349/stroke-biomarkers-in-clinical-practice-a-critical-appraisal
#10
REVIEW
Geelyn J L Ng, Amy M L Quek, Christine Cheung, Thiruma V Arumugam, Raymond C S Seet
Biomarkers provide critical mechanistic insights to key biologic processes that occur during cerebral ischemia which, when carefully applied, can improve clinical decision-making in acute stroke management. The translation of a blood-based biomarker in ischemic stroke to clinical practice is challenging, in part, due to the complexity of ischemic stroke pathogenesis and the presence of a blood-brain barrier that restricts the release of brain-specific markers into the circulation. The pathologic and clinical aspects of ischemic stroke are described in this review, where a non-exhaustive list of biomarkers that interrogate different aspects of ischemic stroke such as oxidative damage, inflammation, thrombus formation, cardiac function and brain injury are described...
January 11, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28088316/individual-female-differences-in-chemoattractant-production-change-the-scale-of-sea-urchin-gamete-interactions
#11
Yasmeen H Hussain, Martin Sadilek, Shukri Salad, Richard K Zimmer, Jeffrey A Riffell
Sperm selection by females is an important process influencing fertilization and, particularly in broadcast-spawning organisms, often occurs before sperm reach the egg. Waterborne sperm chemoattractants are one mechanism by which eggs selectively influence conspecific sperm behavior, but it remains an open question whether the eggs from different females produce different amounts of sperm chemoattractant, and how that might influence sperm behavior. Here, we quantify the differences in attractant production between females of the sea urchin species Lytechinus pictus and use computational models and microfluidic sperm chemotaxis assays to determine how differences in chemoattractant production between females affects their ability to attract sperm...
January 11, 2017: Developmental Biology
https://www.readbyqxmd.com/read/28088252/quantification-of-whey-protein-content-in-infant-formulas-by-sds-cge
#12
Ping Feng, Christophe Fuerer, Adrienne McMahon
Protein separation by SDS-CGE (Sodium Dodecyl Sulfate - Capillary Gel Electrophoresis) followed by UV absorption at 220nm allows quantification of major proteins in raw milk. In processed dairy samples such as skim milk powder and infant formulas, signals from individual proteins are less resolved, but caseins still migrate as one family between two groups of whey proteins. In the first group, α-Lactalbumin and β-Lactoglobulin migrate as two distinct peaks. Lactosylated adducts show delayed migration times and interfere with peak separation, but both native and modified forms, as well as other low molecular weight whey proteins, still elute before the caseins...
November 18, 2016: Journal of AOAC International
https://www.readbyqxmd.com/read/28088214/determinants-and-materno-fetal-outcomes-related-to-cesarean-section-delivery-in-private-and-public-hospitals-in-low-and-middle-income-countries-a-systematic-review-and-meta-analysis-protocol
#13
Idrissa Beogo, Bomar Mendez Rojas, Marie-Pierre Gagnon
BACKGROUND: Despite the well-established morbidity, mortality, long-term effects, and unnecessary extra-cost burden associated with cesarean section delivery (CSD) worldwide, its rate has grown exponentially. This has become a great topical challenge for the international healthcare community and individual countries. Estimated at three times the acceptable rate as defined by the World Health Organization in 1985, the continued upward trend has been fuelled by higher income countries...
January 14, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28088208/stirring-the-motivational-soup-within-person-latent-profiles-of-motivation-in-exercise
#14
Magnus Lindwall, Andreas Ivarsson, Karin Weman-Josefsson, Linus Jonsson, Nikos Ntoumanis, Heather Patrick, Cecilie Thøgersen-Ntoumani, David Markland, Pedro Teixeira
BACKGROUND: The purpose of the present study was to use a person-oriented analytical approach to identify latent motivational profiles, based on the different behavioural regulations for exercise, and to examine differences in satisfaction of basic psychological needs (competence, autonomy and relatedness) and exercise behaviour across these motivational profiles. METHODS: Two samples, consisting of 1084 and 511 adults respectively, completed exercise-related measures of behavioural regulation and psychological need satisfaction as well as exercise behaviour...
January 14, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/28088191/predicting-probable-alzheimer-s-disease-using-linguistic-deficits-and-biomarkers
#15
Sylvester O Orimaye, Jojo S-M Wong, Karen J Golden, Chee P Wong, Ireneous N Soyiri
BACKGROUND: The manual diagnosis of neurodegenerative disorders such as Alzheimer's disease (AD) and related Dementias has been a challenge. Currently, these disorders are diagnosed using specific clinical diagnostic criteria and neuropsychological examinations. The use of several Machine Learning algorithms to build automated diagnostic models using low-level linguistic features resulting from verbal utterances could aid diagnosis of patients with probable AD from a large population...
January 14, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28088186/concentration-of-fine-needle-aspirates-similar-to-molecular-method-improves-sensitivity-of-the-diagnosis-of-tuberculous-lymphadenitis-in-addis-ababa-ethiopia
#16
Olifan Zewdie, Tamrat Abebe, Adane Mihret, Eyob Hirpa, Gobena Ameni
BACKGROUND: Tuberculous lymphadenitis (TBLN) diagnosis has been a true challenge solely by clinical evidence in developing countries, due to limited the diagnostic facility on hand. However, the availability and affordability of available diagnostic tools in resource-limited settings like Ethiopia necessitates the quest for other techniques with added value over direct Z-N microscopy. Therefore, we aimed at to assess whether the concentration of lymph node aspirate similarly improves the detection rate of tuberculous lymphadenitis or not...
January 14, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28088178/health-related-quality-of-life-and-associated-factors-in-functionally-independent-older-people
#17
Mónica Machón, Isabel Larrañaga, Miren Dorronsoro, Kalliopi Vrotsou, Itziar Vergara
BACKGROUND: Health-related quality of life (HRQL) is a key indicator of elderly people's health status that can be affected by different factors. However, little is known about which variables are associated with it in functionally independent elderly people. The aim of this project was to study HRQL and a wide variety of health, lifestyle, social and contextual aspects and their relation to HRQL in a sample of functionally independent, non-cognitively impaired community-dwelling adults, over 65 years of age, from a northern region of Spain...
January 14, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28088177/a-novel-quantitative-pcr-detects-babesia-infection-in-patients-not-identified-by-currently-available-non-nucleic-acid-amplification-tests
#18
Lavoisier Akoolo, Samantha Schlachter, Rasel Khan, Laura Alter, Albert D Rojtman, Kristine Gedroic, Purnima Bhanot, Nikhat Parveen
BACKGROUND: Ticks transmit Babesia microti, the causative agents of babesiosis in North America and Europe. Babesiosis is now endemic in Northeastern USA and affects people of all ages. Babesia species infect erythrocytes and can be transmitted through blood transfusion. Whole blood and blood products, which are not tested for Babesia, can cause transfusion-transmitted babesiosis (TTB) resulting in severe consequences in the immuno-compromised patients. The purpose of this study was epidemiological evaluation of babesiosis in a tick-infested state...
January 14, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28088167/randomized-double-blind-placebo-controlled-clinical-trial-to-assess-the-safety-and-effectiveness-of-a-novel-dual-action-oral-topical-formulation-against-upper-respiratory-infections
#19
Pranab K Mukherjee, Frank Esper, Ken Buchheit, Karen Arters, Ina Adkins, Mahmoud A Ghannoum, Robert A Salata
BACKGROUND: Current prevention options for upper respiratory infections (URIs) are not optimal. We conducted a randomized, double-blinded, placebo-controlled pilot clinical trial to evaluate the safety and efficacy of ARMS-I™ (currently marketed as Halo™) in the prevention of URIs. METHODS: ARMS-I is patented novel formulation for the prevention and treatment of influenza, comprising a broad-spectrum antimicrobial agent (cetylpyridinium chloride, CPC) and components (glycerin and xanthan gum) that form a barrier on the host mucosa, thus preventing viral contact and invasion...
January 14, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28088089/the-traumatic-potential-of-a-projectile-shot-from-a-sling
#20
Igor Borovsky, Zvi Lankovsky, Leonid Kalichman, Victor Belkin
Herein, we analyze the energy parameters of stones of various weights and shapes shot from a sling and based on this data evaluate its traumatic potential. Four police officers proficient in the use of a sling participated in the trials. The following projectile types, shot using an overhead technique at a target 100m away were: round steel balls of different sizes and weights (24mm, 57g; 32mm, 135g; 38mm, 227g); different shaped stones weighing 100-150g and 150-200g and a golf ball (47g). Our data indicated that projectiles shot from unconventional weapons such as a sling, have serious traumatic potential for unprotected individuals and can cause blunt trauma of moderate to critical severity such as fractures of the trunk, limb, and facial skull bone, depending on the weight and shape of the projectile and the distance from the source of danger...
October 26, 2016: Forensic Science International
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