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https://www.readbyqxmd.com/read/27913223/hepatitis-e-virus-infection-beyond-the-liver
#1
REVIEW
S Pischke, J Hartl, S D Pas, A W Lohse, B C Jacobs, A A van der Eijk
Hepatitis E virus (HEV) infections are not limited to the liver but may also affect other organs. Several diseases, including Guillain-Barré syndrome, neuralgic amyotrophy, glomerulonephritis, cryoglobulinemia, pancreatitis, lymphoma, thrombopenia, meningitis, thyreoiditis and myocarditis have been observed in the context of hepatitis E. To date the definite pathophysiological links between HEV and extrahepatic manifestations are not yet established. However, it is suggested that HEV-infection might be causative based on serological studies, case series, in vitro data and animal models...
November 29, 2016: Journal of Hepatology
https://www.readbyqxmd.com/read/27536208/a-rare-case-of-addison-s-disease-hepatitis-thyreoiditis-positive-igg-anti-tissue-transglutaminase-antibodies-and-partial-iga-deficiency
#2
Marta P Baleva, Snejina Mihaylova, Petja Yankova, Iliana Atanasova, Milena Nikolova-Vlahova, Elissaveta Naumova
INTRODUCTION: Selective IgA deficiency (IgAD) is the most prevalent type of primary immune deficiencies, but partial IgA deficiency is even more common. Addison's disease is a rare condition associated with primary adrenal insufficiency due to infection or autoimmune destruction of the adrenals. The association between IgA deficiency and Addison's disease is very rare. CASE AND LABORATORY DATA: We observed a 22-year-old male patient with marked darkening of the skin, especially on the palms and areolae, jaundice on the skin and sclera, astheno-adynamia, hypotension (80/50 mm Hg), and pain in the right hypochondrium...
2016: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/27350133/-fine-needle-aspiration-fna-of-the-thyroid-gland-analysis-of-discrepancies-between-cytological-and-histological-diagnoses
#3
P Dalquen, B Rashed, A Hinsch, R Issa, T Clauditz, A Luebke, J Lüttges, W Saeger, K H Bohuslavizki
BACKGROUND: Diagnostic problems of thyroid cytology are frequently discussed, but relevance and causes of discrepant cytological and histological diagnoses are rarely studied in detail. OBJECTIVES: Investigation of causes and relevance of discrepant diagnoses. MATERIALS AND METHOD: The analysis includes 297 patients who had thyroid resection after prior fine needle aspiration (FNA) and is based on the cytological and histological reports. In special cases, cytological and histological specimens were re-examined...
September 2016: Der Pathologe
https://www.readbyqxmd.com/read/27200606/the-impact-of-treatment-of-thyreoid-disease-in-pregnant-women-to-the-outcome-of-giving-birth
#4
M Ferenczy, K Póhr, Z Lőcsei, A Oláh, I Boncz, I Karácsony, E Salamonné Toldy
No abstract text is available yet for this article.
November 2014: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/26647899/-therapeutic-effect-and-tolerance-of-ipilimumam-in-metastatic-malignant-melanoma-in-children%C3%A2-%C3%A2-a%C3%A2-case-report
#5
V Bajčiová
BACKGROUND: Malignant melanoma is a rare malignancy in the pediatric population. Etiology is usually unknown. Clinical symptoms are nonspecific, clinical behavior and biology features may differ from those in an adult population. The most important prognostic factor is spread of disease. Surgical resection is treatment of choice for localized melanoma. Advanced and metastatic melanoma is still an incurable disease. CASE: We are presenting an eight-year- old boy with metastatic malignant melanoma of unknown origin based on TP53 mutation (Li Fraumeni syndrome)...
2015: Klinická Onkologie: Casopis Ceské a Slovenské Onkologické Spolecnosti
https://www.readbyqxmd.com/read/25873114/-our-experience-with-hormonal-therapy-in-transsexual-patients
#6
Vladimír Weiss, Petr Weiss, Hana Fifková
Hormonal therapy in transsexual patients (TS) includes sexagens administration: androgens in female-to-male transsexual patients (FtM) and oestrogens and antiandrogens in male-to-female transsexual patients (MtF). Duration of hormonal therapy should continue at least 1 year before gender reassignment surgery. Hormonal therapy supresses former gender and induces partially new gender changes. Hormonal therapy continues subsequently after surgery during life. Hormonal therapy in MtF TS includes oestrogens and antiandrogens application...
March 2015: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/23964913/-giant-cell-interstitial-pneumonia-without-exposure-to-hard-metals
#7
Barbora Krajsová, Tomáš Tichý
We describe the case of a 58-year-old woman with giant cell interstitial pneumonia without any history of exposure to hard metals. Giant cell interstitial pneumonia (GIP) is a rare interstitial lung disease characterized by the presence of numerous multinucleated giant cells in the alveolar spaces. Currently GIP is regarded as secondary interstitial pneumonia. While it has become almost synonymous with hard metal lung disease (cobalt pneumonitis), the literature has also included sporadic cases of GIP without exposure to hard metals...
June 2013: Ceskoslovenská Patologie
https://www.readbyqxmd.com/read/23256828/-is-polycystic-ovary-syndrome-associated-with-autoimmune-thyroiditis
#8
J Petríková, J Figurová, I Dravecká, I Lazúrová
INTRODUCTION: Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in women of fertile age and lately there is a discussion about its possible association with autoimmune diseases. The aim of the study was to examine incidence of autoimmune thyreoiditis (AIT) in PCOS women. PATIENTS AND METHODS: 64 PCOS patients were enrolled and 68 healthy menstruating women served as controls. All subjects were examined for thyrotropin (TSH), free thyroxin (fT4) and the presence as well as titers of antithyroid antibodies aTG (anti-thyreoglobulin) and aTPO (anti-thyreoperoxidase)...
November 2012: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/22366023/-cardiac-conductive-disease-with-atrial-fibrillation-in-a-chinese-pedigree-and-evaluation-of-the-treatments
#9
Fuqiang Liu, Yan Li, Yong Xie, Donghua Zhao, Zhongbo Xiao, Guifang Zhou, Jian Peng
OBJECTIVE: To investigate the clinical characteristics of a Chinese pedigree with cardiac conductive disease complicated by atrial fibrillation and the therapeutic effect of the treatments. METHODS: All the family members including the proband were screened with routine examination, electrocardiography, echocardiograpy, Holter recording, chest X-ray, blood biochemistry tests and autoantibody test. The proband received dual chamber pacemaker implantation combined with oral amiodarone treatment for 3 months...
January 2012: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/21957775/-thyreopathy-in-primary-care
#10
REVIEW
P Vlcek
Thyroid gland disorders, as the core of all endocrinopathies, affect 5-7% of the population of the Czech Republic, with women being affected 6-8 times more often than men. Clinically, thyreopathies are divided into hormonal production disorders and morphology disorders. Thyroid hormones fT3, fT4 and TSH serum levels determine the diagnosis of a thyroid gland disorder. Primary hypothyreosis is characterized by reduced fT4 and increased TSH. Low T3 syndrome is a protective reaction of the organism and is associated with conversion of T4 into hormonally inactive triiodothyronine (rT3)...
September 2011: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/21656487/-diagnosis-and-therapy-of-hyperthyreosis
#11
REVIEW
Jan Krützfeldt, Emanuel R Christ
Hyperthyreosis, diabetes and calcium disorders are frequent endocrine diseases that are often encountered by the primary care physician. The diagnosis of hyperthyreosis can be established by many different laboratory and analytical tests. However, the clinical context can often guide a specific diagnostic approach. Graves disease and toxic adenomas are the most frequent causes of hyperthyreosis. Diagnosis of Graves disease is most frequent between age 35 and 60 and about 10-20% of patients show already initially signs of endocrine orbithopathy...
June 2011: Therapeutische Umschau. Revue Thérapeutique
https://www.readbyqxmd.com/read/21398213/-diabetes-and-thyroid-disorders
#12
REVIEW
Péter Reismann, Anikó Somogyi
Both diabetes mellitus and thyroid disorders are common diseases. According to epidemiologic studies the prevalence of specific thyroid disorders in diabetic subjects is two times higher. Risk factors are age, female gender and autoimmune diabetes mellitus. However, thyroid disorders are diagnosed only half of the cases in diabetic population. The review briefly summarizes the association of autoimmune diabetes mellitus and thyreoiditis, the risk of thyroid disorders in type 1 diabetic pregnant women. Furthermore, the influence of obesity in the risk on thyroid cancer and the effect of glucagon-like peptide 1 analogue on thyroid medullary C-cells are discussed...
March 27, 2011: Orvosi Hetilap
https://www.readbyqxmd.com/read/21335070/additive-inhibitory-effects-of-calcitonin-and-capsaicin-on-voltage-activated-calcium-channel-currents-in-nociceptive-neurones-of-rat
#13
T Hagenacker, D Ledwig, D Büsselberg
Calcitonin, a peptide hormone expressed in C-cells of the thyreoid gland, as well as capsaicin, isolated from chili, both, modify intracellular signalling in nociceptive neurones. The pathways triggered by the activation of either of these receptors results in a modulation of the intracellular calcium ([Ca(2+)](i)) concentration. While the regulation of [Ca(2+)](i) depends on many factors, voltage activated calcium channels (VACCs) are a major gate for the calcium entry into neurones. Here we describe the changes of voltage gated calcium channel currents (I(Ca(V))) induced by calcitonin and/or capsaicin...
April 25, 2011: Brain Research Bulletin
https://www.readbyqxmd.com/read/21312779/acute-thyreoiditis
#14
R T de Hellebranth
No abstract text is available yet for this article.
January 1933: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/21225554/-atypical-celiac-disease-in-a-patient-with-type-1-diabetes-mellitus-and-hashimoto-s-thyreoiditis
#15
F S Schreiber, T Ziob, M Vieth, H Elsbernd
HISTORY AND ADMISSION FINDINGS: A 49-year-old man presented with a four-week history of fatigue and physical weakness. He was of slender build (BMI 19,5 kg/m (2)) and pale. He also had vitiligo. Diabetes mellitus type 1 and Hashimoto thyreoiditis had been previously diagnosed. INVESTIGATIONS: Laboratory tests revealed iron deficiency anemia with depleted iron reserves (hemoglobin 5,9 g/dl; normal range 14,0 - 18,0). Vitamin B (12) and folic acid were also low. A probable cause was thought to be malabsorption...
January 2011: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/20432751/thyroid-fine-needle-aspiration-cytology-in-children-and-adolescents
#16
Sandra Moslavac, Neven Matesa, Zvonko Kusić
Thyroid fine needle aspiration cytology (FNAC) is the most accurate and cost effective method in the evaluation of the thyroid nodule and has been commonly used in adults. Thyroid nodules are uncommon in younger patients (1-2%). Our aim was to determine some relevant clinical and cytological parameters in this demographic group. Ultrasound-guided thyroid FNACs performed from May 1995 to June 2008 in patients under 18 years of age were retrospectively reviewed. The following clinical parameters were retrieved: age and gender, number of nodules, and nodule size...
March 2010: Collegium Antropologicum
https://www.readbyqxmd.com/read/20412698/interferon-alpha-for-maintenance-of-remission-in-churg-strauss-syndrome-a-long-term-observational-study
#17
Claudia Metzler, Elena Csernok, Wolfgang L Gross, Bernhard Hellmich
BACKGROUND: Interferon-alpha has been successfully used for induction of remission in patients with Churg-Strauss syndrome, but data on its ability to prevent relapses and its safety during long-term use are lacking. OBJECTIVES: To examine the safety and efficacy of interferon-alpha for mainten-ance of remission in Churg-Strauss syndrome. PATIENTS AND METHODS: In a prospective open-label long-term observational study, 13 patients with CSS in stable remission received interferon-alpha (3 x 3 Mio...
January 2010: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/20063468/-surgical-treatment-of-pulmonary-metastases-surgical-methods-early-and-long-term-results
#18
D Petrov, M Stanoev, M Plochev, E Goranov, V Dzhambazov
AIM: To retrospectively evaluate the postoperative results after surgery for lung metastases from extrapulmonary origin. METHODS: A total of 45 patients were operated on for lung metastases between Jan 1996 and Dec 2006. They were 22 (48.9%) male and 23 (51.1%) female with a mean age of 51.6 years. Unilateral operation was carried out in 34 (75.6%) of the patients and another 11 (24.4%) patients were operated on for bilateral metastases. In 8 of them a one-stage operation was performed via median sternotomy (6) and bilateral successive thoracotomies (2)...
2008: Khirurgiia
https://www.readbyqxmd.com/read/19969962/metastatic-tumours-in-the-thyreoid-gland
#19
R A Willis
No abstract text is available yet for this article.
May 1931: American Journal of Pathology
https://www.readbyqxmd.com/read/19517357/-interferon-alpha-as-treatment-option-in-severe-persistent-uncontrolled-bronchial-asthma-an-open-label-study
#20
C Kroegel, N Bergmann, C Heider, A Moeser, J Happe, Y Schlenker, B Bartuschka, M Henzgen, R Walther, A Reissig, M Foerster
BACKGROUND: The purpose of this study was to evaluate the long-term safety and therapeutic effects of IFN-alpha in patients with severe persistent uncontrolled asthma on long-term oral glucocorticoid (GC) treatment. PATIENTS AND METHODS: The study included 16 patients (2 male, 14 female; age 39 years [range: 24 - 63]) with severe persistent asthma. Diagnosis and severity classification of asthma were established according to the guidelines of the "Deutsche Atemwegsliga"...
June 2009: Pneumologie
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