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neonatal jaundice and sepsis

Karen Whitfield, Claudia Barkeij, Angela North
AIM: To present a case of an extremely premature infant and the role that the specialist neonatal pharmacist has on the quality of care of these patients. METHOD: Interventions and recommendations made by the pharmacists over the admission of a triplet born at 23 weeks and 5 days gestation were recorded. The type of interventions were categorised and classified for risk using a consequence/probability matrix.1 RESULTS: The patient required admission to the intensive care unit and subsequently the special care unit for a period of 163 days before discharge home...
September 2016: Archives of Disease in Childhood
Daynia E Ballot, Gilbert Rugamba
Background. Severe hyperbilirubinaemia requiring exchange transfusion has become less common in recent years; however, kernicterus still occurs. The aim of this study was to review babies undergoing exchange transfusion for severe hyperbilirubinaemia in a Johannesburg hospital. Methodology. This was a retrospective review of babies who required exchange transfusion in both the neonatal and the paediatric wards from June 1, 2006, to December 31, 2011. Results. There were 64 patients who underwent 67 exchange transfusions...
2016: International Scholarly Research Notices
Abieyuwa A Emokpae, Cecilia A Mabogunje, Zainab O Imam, Bolajoko O Olusanya
BACKGROUND: A novel filtered-sunlight phototherapy (FSPT) device has been demonstrated to be safe and efficacious for treating infants with neonatal jaundice in resource-constrained tropical settings. We set out to provide baseline data for evaluating the clinical impact of this device in a referral pediatric hospital. METHODS: We reviewed the medical records of infants admitted for neonatal hyperbilirubinemia in an inner-city Children's Hospital in Lagos, between January 2012 and December 2014 to determine the pattern, treatment and outcomes during the pre-intervention period...
2016: PloS One
S Budhathoki, P Poudel, N K Bhatta, R R Singh, M K Shrivastava, S R Niraula, B Khanal
Low birth weight (LBW) remains an important cause of newborn morbidity and mortality. A hospital based prospective and descriptive study was conducted at Paediatric wards, Nursery, Neonatal intensive unit (NICU) and Post natal ward during period of June to October 2010 to note the clinico-epidemiological profile of Low Birth Weight (LBW) newborns. Incidence of the LBW babies in our hospital was 14.45%; more than four fifth (82.2%) baby's mothers were primigravida. Eighty two percent mothers had unbooked pregnancies...
December 2014: Nepal Medical College Journal: NMCJ
Ghulam Nabi Rather, Muzafar Jan, Wasim Rafiq, Imran Gattoo, Sheikh Quyoom Hussain, Mohmad Latief
INTRODUCTION: The morbidity and mortality pattern in late preterm infants is higher than term infants (gestational age ≥ 37weeks). The main reason behind that is the relative physiologic and metabolic immaturity, though there is no significant difference in the weight or the size of the two groups. AIM: The present study was undertaken to study the incidence, early neonatal morbidity and mortality (within first 7 days of life) in late preterm infants (34 - 36 6/7 weeks)...
December 2015: Journal of Clinical and Diagnostic Research: JCDR
Ehsan Alaee, Mohsen Sirati, Mohammad Hossein Taziki, Mahnaz Fouladinejad
BACKGROUND: Hearing impairment, as one of the most common birth defects, is a hidden disability with negative impacts on speech and cognitive development. OBJECTIVES: The aim of this study was to assess the prevalence of sensorineural hearing loss (SNHL) and determine the associated risk factors among infants admitted to neonatal intensive care units (NICUs) and neonatal wards of teaching hospitals, affiliated to Golestan University of Medical Sciences, Gorgan, Iran...
December 2015: Iranian Red Crescent Medical Journal
Manoochehr Mahram, Sonia Oveisi, Najmeh Jaberi
Hyperbilirubinemia is a common problem in neonates and causes serious complications. Thus, serial measurements of bilirubin should be done. This assessment is done through two methods of laboratory measurement in serum sample and transcutaneous bilirubinometer. This descriptive study compared transcutaneous bilirubin assessment and laboratory serum bilirubin. Bilirubin level was assessed among 256 neonates admitted to the Qods Children's Hospital in Qazvin- Iran, because of neonatal indirect jaundice, through two methods of transcutaneous bilirubinometery from two sites of forehead and sternum and laboratory measurement of bilirubin in serum...
December 2015: Acta Medica Iranica
Izeta Softić, Husref Tahirović, Mensuda Hasanhodžić
OBJECTIVE: The aim of the study was to determine the epidemiological characteristics of bacterial meningitis observed in neonates born in the Department of Gynaecology and Obstetrics, University Clinical Centre Tuzla, Bosnia and Herzegovina, admitted to Intensive care unit (NICU) or readmitted, because of suspected infection, after discharge from the nursery. SUBJECTS AND METHODS: This study was carried out from July 1, 2012 to June 30, 2013. During this period 4136 neonates were born...
2015: Acta Medica Academica
T Malla, S Singh, P Poudyal, B Sathian, G Bk, K K Malla
BACKGROUND: An exchange transfusion involves replacing patient's blood with donor blood in order to remove abnormal blood components and circulating toxins while maintaining adequate circulating blood volume. OBJECTIVE: To observe the incidence, causes of jaundice requiring Exchange and any adverse event of exchange transfusion in newborns with unconjugated hyperbilirubinemia. METHOD: Prospective study undertaken at Neonatal Intensive Care Unit (NICU) of Manipal Teaching Hospital, Pokhara, Nepal from March 2014 to April 2015...
April 2015: Kathmandu University Medical Journal (KUMJ)
Vishal Kapoor, Rebecca Glover, Manoj N Malviya
BACKGROUND: The pure soybean oil based lipid emulsions (S-LE) conventionally used for parenteral nutrition (PN) in preterm infants have high polyunsaturated fatty acid (PUFA) content. The newer lipid emulsions (LE) from alternative lipid sources with reduced PUFA content may improve clinical outcomes in preterm infants. OBJECTIVES: To determine the safety and efficacy of the newer alternative LE compared with the conventional S-LE for PN in preterm infants. SEARCH METHODS: We used the standard search strategy of the Cochrane Neonatal Review Group (CNRG) to search the Cochrane Central Register of Controlled Trials (CENTRAL; Issue 7), MEDLINE (1946 to 31 July 2015), EMBASE (1947 to 31 July 2015), CINAHL (1982 to 31 July 2015), Web of Science (31 July 2015), conference proceedings, trial registries (clinicaltrials...
2015: Cochrane Database of Systematic Reviews
Lucia Corradin, Musa Hindiyeh, Rasha Khaled, Fadi Rishmawi, Marwan Zidan, Hiyam Marzouqa
This study describes the epidemiology of infants' hearing loss (IHL) among patients under 3 months of age at Caritas Baby Hospital, the only pediatric hospital in Palestine. It was aimed to demonstrate that IHL is a major health problem in Palestine and to assess the first available data of the newborn hearing screening program conducted between September 25, 2006 and December 31, 2011. Data was uploaded and analyzed using Microsoft Excel and the Statistical Package for the Social Sciences software (SPSS version 21)...
March 6, 2014: Audiology Research
Paul Walsh, Pádraig Cunningham, Sabrina Merchant, Nicholas Walker, Jacquelyn Heffner, Lucas Shanholtzer, Stephen J Rothenberg
BACKGROUND AND OBJECTIVES: Central apnea complicates, and may be the presenting complaint in, bronchiolitis. Our objective was to prospectively derive candidate clinical decision rules (CDRs) to identify infants in the emergency department (ED) who are at risk for central apnea. METHODS: We conducted a prospective observational study over 8 years. The primary outcome was central apnea subsequent to the initial ED visit. Infants were enrolled if they presented with central apnea or bronchiolitis...
November 2015: Pediatrics
Michele Mussap, Elisabetta Puxeddu, Melania Puddu, Giovanni Ottonello, Ferdinando Coghe, Paola Comite, Francesco Cibecchini, Vassilios Fanos
Neonatal sepsis still remains a major cause of morbidity and mortality in neonatal intensive care unit (NICU). Recently, soluble CD14 subtype (sDC14-ST) also named presepsin, was proposed as an effective biomarker for diagnosing, monitoring, and assessing the risk of neonatal sepsis and septic shock. The aim of this study was to investigate the diagnostic accuracy of sCD14-ST presepsin in diagnosing neonatal bacterial sepsis and in discriminating non-bacterial systemic inflammatory response syndrome (SIRS) from bacterial sepsis...
December 7, 2015: Clinica Chimica Acta; International Journal of Clinical Chemistry
Salil S Gadkari, Sucheta R Kulkarni, Rushita R Kamdar, Madan Deshpande
The management of retinopathy of prematurity (ROP) can be challenging in preterm babies with a gestational age <30 weeks, those with very low birth weight and multiple risk factors (eg., oxygen therapy for respiratory distress, sepsis, neonatal jaundice). A premature infant presented with "hybrid" zone 1 disease in the right eye and aggressive posterior ROP in the left eye. Both eyes were adequately treated with laser photocoagulation; however, the eyes deteriorated and progressed to stage 4 ROP. Both eyes eventually underwent intravitreal bevacizumab followed by lens sparing vitrectomy with good anatomical and visual outcome...
July 2015: Middle East African Journal of Ophthalmology
Vykuntaraju K Gowda, Anil Kumar, Sanjay K Shivappa, Praveen Kumar Srikanteswara, Shivananda, M S Mahadeviah, M Govindraj, Premalatha Ramaswamy
INTRODUCTION: Cerebral palsy (CP) is the most common physical disorder of children. Causes like jaundice and birth injury though are decreasing; complications resulting from the survival of low birth weight babies are replacing some of the older etiologies. Hence, this study was planned. OBJECTIVES: The objective was to study the clinical patterns, predisposing factors, and co-morbidities in children with CP. MATERIALS AND METHODS: The present study is a hospital based prospective study conducted from January 2012 to January 2013 in children presenting to neurodevelopmental clinic at a tertiary care teaching hospital in India...
April 2015: Journal of Pediatric Neurosciences
Rehana A Salam, Jai K Das, Chesarahmia Dojo Soeandy, Zohra S Lassi, Zulfiqar A Bhutta
BACKGROUND: Infections during pregnancy confers increased risk of maternal and perinatal morbidity and mortality. However, the case for advocating Haemophilus influenzae type B (Hib) and viral Influenza vaccinations in pregnancy is still debatable. OBJECTIVES: To assess the impact of Hib and viral Influenza vaccinations during pregnancy on maternal, neonatal and infant health outcomes compared to placebo/control. SEARCH METHODS: We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (29 January 2015) and reference lists of retrieved studies...
2015: Cochrane Database of Systematic Reviews
Jaishri Ramji, Rakesh S Joshi, Mitesh Bachani, Dungarsingh Rathore
The syndromic form of biliary atresia accounts for 10-25% and is associated with a poor prognosis due to associated anomalies. We report a case of extrahepatic biliary atresia and polysplenia syndrome with jaundice since 19th day of life and who had undergone surgical correction of malrotation in the neonatal period. Inspite of successful Kasai's portoenterostomy at 52nd day of life, the child succumbed to post-operative sepsis.
October 2013: Journal of Neonatal Surgery
Nandita Chattopadhyay, Kaninika Mitra
BACKGROUND: High risk newborns are most vulnerable to develop neuro-developmental delay (NDD). Early detection of delay in this group and identification of associated perinatal factors and their prevention can prevent disability in later life. DESIGN AND METHODS: Observational cohort study. Field based tracking and neuro-developmental screening of high risk newborns discharged between January 2010 to June 2012 from a district Hospital in India was conducted by a team of developmental specialists, using standardized tools like Denver Developmental Screening Tool II, Trivandrum Developmental Screening Chart and Amiel-Tison method of tone assessment...
February 20, 2015: Journal of Public Health Research
Nawfal I Nawfal, Mohamad K Ramadan, Ahmad Salah El Dine Naja, Mariam A Rajab
BACKGROUND: There has been a decrease in the mean gestational age at delivery worldwide mostly due to an increase in deliveries occurring at late preterm period (LPP) with a concomitant rise in the rate of morbidities among newborns delivered at this period. OBJECTIVES: To report the frequency of common short-term neonatal morbidities in infants born at LPP (between 34(0/7) and 36(6/7) weeks' gestation) and to compare these frequencies with those of full-term infants born at our institution...
October 2014: Le Journal Médical Libanais. the Lebanese Medical Journal
Daragh Finn, Sinéad M O'Neill, Aedin Collins, Ali S Khashan, Keelin O'Donoghue, Eugene Dempsey
OBJECTIVE: To assess neonatal outcomes following elective caesarean delivery (CD) at term (≥37 + 0 weeks gestation). METHODS: A retrospective cohort study was conducted in a single Irish maternity hospital. Elective CDs at term between August 2008 and July 2012 were reviewed. Outcome measures were admission to the neonatal intensive care unit (NICU), length of stay, respiratory complications, hypoglycaemia, jaundice, newborn sepsis and medical interventions...
March 2016: Journal of Maternal-fetal & Neonatal Medicine
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