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https://www.readbyqxmd.com/read/27647036/the-utility-of-single-photon-emission-computed-tomography-in-defining-painful-upper-cervical-facet-arthropathy
#1
Vijay M Ravindra, Marcus D Mazur, Erica F Bisson, Craig Barton, Lubdha M Shah, Andrew T Dailey
OBJECTIVE: Standard imaging techniques have low predictive value for identifying sources of neck pain. Single-photon emission computed tomography (SPECT) imaging in conjunction with CT provides the sensitivity of bone scanning for areas of high metabolic activity with the sensitivity of CT for anatomic localization. We evaluated the utility of SPECT-CT imaging in identifying pain generators in upper cervical facet arthropathy. METHODS: In a retrospective study, we reviewed seven patients (mean age 68...
September 16, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27544679/lumbar-scoliosis-associated-with-spinal-stenosis-in-idiopathic-and-degenerative-cases
#2
REVIEW
J C Le Huec, A Cogniet, S Mazas, A Faundez
UNLABELLED: Degenerative de novo scoliosis is commonly present in older adult patients. The degenerative process including disc bulging, facet arthritis, and ligamentum flavum hypertrophy contributes to the appearance of symptoms of spinal stenosis. Idiopathic scoliosis has also degenerative changes that can lead to spinal stenosis. PURPOSE: The aetiology, prevalence, biomechanics, classification, symptomatology, and treatment of idiopathic and degenerative lumbar scoliosis in association with spinal stenosis are reviewed...
October 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/27481600/minimally-invasive-surgical-management-of-thoracic-ossification-of-the-ligamentum-flavum-associated-with-x-linked-hypophosphatemia
#3
Alexander R Riccio, Pouya Entezami, Anthony Giuffrida, John Dowling, George Forrest, John W German
BACKGROUND: X-linked hypophosphatemia (XLH) is the most common inherited form of renal phosphate wasting and inherited rickets. Patients have hyperplasia of fibrochondrocytes in tendons and ligaments, causing the structures to thicken and calcify. Thickening of the lamina, hypertrophy of facet joints, and calcification of spinal ligaments are sequelae of this condition and can result in central or foraminal stenosis that compresses nerve roots or the spinal cord. We present a case of XLH with calcification of the ligamentum flavum in which the patient was operated on using minimally invasive posterior decompression...
October 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27299082/degenerative-sacrolisthesis-of-s1-s2-a-case-report
#4
Thakre Kunwar Rajendra, Thomas Issac, B Mallikarjuna Swamy
INTRODUCTION: Degenerative spondylolisthesis (DS) is usually seen at L4-L5 level and less frequently at L5-S1 level. This is a rare case report of spondylolisthesis of S1 over S2 with lumbarization of S1. Lumbarization of S1 is seen in just 1-2% of the population and to have spondylolisthesis in this segment is even rarer. The purpose is to report a rare case of DS at S1-S2 level. CASE REPORT: This is a single case report of a 66-year-old gentleman who presented with complains of lower backache for 2 years and acute retention of urine to the emergency department...
July 2015: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/27228518/facetoplasty-using-radiofrequency-thermocoagulation-for-facet-joint-hypertrophy
#5
Jinyoung Oh, Daehyun Jo, Koohyun Kim, Jungwoo Shim, Misun Roh
UNLABELLED: Lumbar spinal stenosis is one of most common pathologic conditions affecting the lumbar spine. Pain and/or disability in the low back and lower extremities with or without neurogenic claudication may occur as a result of compression of dural sac contents or nerve roots in the narrowed space. Bulging and protrusion, facet joint hypertrophy, and disc herniation combined with osteophytes and arthritic changes of facet joints can be the cause of lumbar spinal stenosis. Medical/interventional treatment may be considered as an initial treatment for patients with mild symptoms of lumbar spinal stenosis...
May 2016: Pain Physician
https://www.readbyqxmd.com/read/27104789/-gluteal-insufficiency-pathogenesis-diagnosis-and-therapy
#6
N Harrasser, I Banke, H Gollwitzer, F Wilken, A Toepfer, R von Eisenhart-Rothe, M Hauschild
INTRODUCTION: Gluteal insufficiency is a common and challenging complaint. New concepts in pathobiomechanics and improved clinical understanding of chronic gluteal dysfunction have unmasked gluteus medius (GMed) tears as an underlying cause of enhanced trochanteric pain syndrome (GTPS). These tears are often missed or misdiagnosed as bursitis, but lead to prolonged chronic peritrochanteric pain. Clinic: The clinical signs are often dull pain on the lateral hip aspect, reduced hip abduction strength with positive Trendelenburg testing and a tendency for the leg to external rotation, as the internal rotation strength is reduced...
April 2016: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/27041884/factors-affecting-results-of-fluoroscopy-guided-facet-joint-injection-probable-differences-in-the-outcome-of-treatment-between-pure-facet-joint-hypertrophy-and-concomitant-diseases
#7
Akif Albayrak, Baris Ozkul, Mehmet Bulent Balioglu, Yunus Atici, Muhammet Zeki Gultekin, Merih Dilan Albayrak
STUDY DESIGN: Retrospective cohort study. PURPOSE: Facet joints are considered a common source of chronic low-back pain. To determine whether pathogens related to the facet joint arthritis have any effect on treatment failure. MATERIALS AND METHODS: Facet joint injection was applied to 94 patients treated at our hospital between 2011 and 2012 (mean age 59.5 years; 80 women and 14 men). For the purpose of analysis, the patients were divided into two groups...
January 2016: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/27002661/ligamentum-flavum-thickening-at-lumbar-spine-is-associated-with-facet-joint-degeneration-an-mri-study
#8
Ergun Karavelioglu, Emre Kacar, Yucel Gonul, Mehmet Eroglu, Mehmet Gazi Boyaci, Selma Eroglu, Ebru Unlu, Alper Murat Ulasli
OBJECTIVE: Degenerative changes in posterior elements of the spine such as thickening or hypertrophy of the ligamentum flavum (LF) may result in spinal stenosis. In the present study, we aimed to investigate the potential factors including age, intervertebral disc degeneration (IDD), facet joint degeneration (FJD), end plate degeneration (EPD), which may affect LF thickening and to reveal the relationship among those factors at each level of lumbar spine by evaluating the magnetic resonance images (MRI)...
November 21, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27001422/cardiac-salvage-by-tweaking-with-beta-3-adrenergic-receptors
#9
REVIEW
Jean-Luc Balligand
Overstimulation of the orthosympathetic system leads to cardiovascular cell and tissue damage through prolonged activation of β-1-2 adrenergic receptors (BARs). The more recent identification of the third isotype of BAR (B3AR) in cardiac myocytes and endothelial cells with a distinctive coupling and effect on cardiac function and remodelling introduced a new facet to this paradigm. In particular, B3AR is up-regulated in cardiac disease and less prone to homologous desensitization, which may reinforce its influence on the diseased myocardium...
July 15, 2016: Cardiovascular Research
https://www.readbyqxmd.com/read/26905253/posteromedial-ankle-impingement-caused-by-hypertrophy-of%C3%A2-talocalcaneal-coalition-a-report-of-five-cases-and-introduction-of-a-novel-index-system
#10
Weidong Song, Wenzhou Liu, Binghao Chen, Adytia Anand, Xiangyu Cheng, Tao Yang
Ankle impingement syndromes are common disorders that can be attributed to many factors. To the best of our knowledge, posteromedial ankle impingement syndromes caused by talocalcaneal coalition have never been previously reported. The present report describes 5 patients with posteromedial ankle pain and inversion limitation. The physical examination, radiographic, and magnetic resonance imaging findings suggested posteromedial ankle impingement syndrome and talocalcaneal coalition. The 5 patients underwent surgery after conservative treatment had failed...
February 20, 2016: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/26858219/comparison-of-the-ventral-epidural-spreading-in-modified-interlaminar-approach-and-transforaminal-approach-a-randomized-double-blind-study
#11
Eung Don Kim, Mi Sun Roh, Jun Jae Park, Daehyun Jo
OBJECTIVE: To evaluate the effectiveness of a modified interlaminar (MIL) approach for accessing ventral epidural space compared with the transforaminal (TF) approach. STUDY DESIGN: Randomized double blinded control trial METHODS: Eighty-four patients with lumbar radicular pain were randomly assigned into two groups in which drug delivery to the ventral epidural space was performed through either the MIL (n = 42) or the TF approach (n = 42)...
September 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/26771373/lumbar-paraspinal-muscle-morphometry-and-its-correlations-with-demographic-and-radiological-factors-in-adult-isthmic-spondylolisthesis-a-retrospective-review-of-120-surgically-managed-cases
#12
Sumit Thakar, Laxminadh Sivaraju, Saritha Aryan, Dilip Mohan, Narayanam Anantha Sai Kiran, Alangar S Hegde
OBJECTIVE The objective of this study was to assess the cross-sectional areas (CSAs) of lumbar paraspinal muscles in adults with isthmic spondylolisthesis (IS), to compare them with those in the normative population, and to evaluate their correlations with demographic factors and MRI changes in various spinal elements. METHODS The authors conducted a retrospective study of patients who had undergone posterior lumbar interbody fusion for IS, and 2 of the authors acting as independent observers calculated the CSAs of various lumbar paraspinal muscles (psoas, erector spinae [ES], multifidus [MF]) on preoperative axial T2-weighted MR images from the L-3 to L-5 vertebral levels and computed the CSAs as ratios with respect to the corresponding vertebral body areas...
May 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/26724634/congenital-malrotation-of-the-atlas-with-unilateral-hypertrophy-of-the-atlanto-occipital-joint-a-rare-anomaly-of-the-craniovertebral-junction-and-its-management
#13
Pratap Chandra Nath, Sudhansu Sekhar Mishra, Rama Chandra Deo, Itibrata Mahanta
BACKGROUND: Congenital anomalies are commonly encountered in the craniovertebral junction because of its unique embryologic development. The craniovertebral junction usually comprises the occiput, atlas, and axis. However, malrotation of the atlas (C1) in between the occiput (C0) and axis (C2) with Chiari I malformation as well as unilateral hypertrophy of the atlanto-occipital joint and a lateral mass manifesting features of high cervical myelopathy is a rarely reported anomaly. CASE DESCRIPTION: A 22-year-old woman presented to us with high cervical compressive myelopathy...
April 2016: World Neurosurgery
https://www.readbyqxmd.com/read/26712393/-necessity-of-intraoperative-three-dimensional-navigation-for-low-lumbar-spine-a-randomized-controlled-study
#14
RANDOMIZED CONTROLLED TRIAL
Xiao Han, Wei Tian, Bo Liu, Da He, Nan Li, Yanwei Lü, Kai Yan, Peihao Jin
OBJECTIVE: To compare the accuracy of lower lumbar pedicle screw placement at different levels with or without navigation system. METHODS: A prospective randomized controlled trial was conducted for patients undergoing open lumbar surgery with pedicle screws at both L4 and L5 levels from March 2011 to May 2012. The accuracy of pedicle screws at L4 and L5 level were evaluated by three-dimensional postoperative computed tomography (CT). There was no apparent violation of pedicle or < 2 mm perforation of pedicle in non-violation group while ≥ 2 mm perforation of pedicle in violation group...
June 16, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/26571175/microrna-221-regulates-hypertrophy-of-ligamentum-flavum-in-lumbar-spinal-stenosis-by-targeting-timp-2
#15
Yun-qiang Xu, Zhen-hui Zhang, Yong-fa Zheng, Shi-qing Feng
STUDY DESIGN: A study of lumbar ligamentum flavum (LF). OBJECTIVE: The aim of this study was to identify LF hypertrophy related microRNAs (miRNAs) expression profile and to investigate the role of miRNAs in the development of LF hypertrophy in lumbar spinal stenosis (LSS). SUMMARY OF BACKGROUND DATA: Although histologic and biologic literature on LF hypertrophy is available, the pathomechanism is still unknown. Accumulating evidence suggests that microRNAs (miRNAs) participate in many physiologic processes, including cell proliferation, differentiation, and fibrosis, but the role of specific miRNAs involved in LF hypertrophy remains elusive...
February 2016: Spine
https://www.readbyqxmd.com/read/26555840/isolation-and-characterization-of-human-mesenchymal-stem-cells-from-facet-joints-and-interspinous-ligaments
#16
Baldur Kristjánsson, Worawat Limthongkul, Wicharn Yingsakmongkol, Pattarawat Thantiworasit, Napaphat Jirathanathornnukul, Sittisak Honsawek
STUDY DESIGN: A descriptive in vitro study on isolation and differentiation of human mesenchymal stem cells (MSCs) derived from the facet joints and interspinous ligaments. OBJECTIVE: To isolate cells from the facet joints and interspinous ligaments and investigate their surface marker profile and differentiation potentials. SUMMARY OF BACKGROUND DATA: Lumbar spinal canal stenosis and ossification of the posterior longitudinal ligament are progressive conditions characterized by the hypertrophy and ossification of ligaments and joints within the spinal canal...
January 2016: Spine
https://www.readbyqxmd.com/read/26535113/case-report-a-case-report-highlighting-bilateral-edb-wasting-as-a-clinical-marker-for-lumbar-canal-stenosis
#17
Bijoy Mohan Kumar, Sunil Munakomi
Herein we discuss a case of a 55 year old male presenting with history suggestive of sciatica on the left leg. Straight leg raising (SLR) test was positive at 45 degrees on the left side. His ankle reflex was absent and the power of extensor hallusus longus (EHL) was 4/5 on the same side. MRI lumbosacral spine revealed left paramedian disc prolapsed on L4/L5 level with spinal canal diameter of 9mm.However since his bilateral extensor digitorm brevis (EDB) were wasted, we suspected associated lumbar canal stenosis and thereby opted for laminectomy and discectomy in this case...
2015: F1000Research
https://www.readbyqxmd.com/read/26484858/behind-the-link-between-copper-and-angiogenesis-established-mechanisms-and-an-overview-on-the-role-of-vascular-copper-transport-systems
#18
REVIEW
Emanuela Urso, Michele Maffia
Angiogenesis critically sustains the progression of both physiological and pathological processes. Copper behaves as an obligatory co-factor throughout the angiogenic signalling cascades, so much so that a deficiency causes neovascularization to abate. Moreover, the progress of several angiogenic pathologies (e.g. diabetes, cardiac hypertrophy and ischaemia) can be tracked by measuring serum copper levels, which are being increasingly investigated as a useful prognostic marker. Accordingly, the therapeutic modulation of body copper has been proven effective in rescuing the pathological angiogenic dysfunctions underlying several disease states...
2015: Journal of Vascular Research
https://www.readbyqxmd.com/read/26435805/lumbar-stenosis-a-recent-update-by-review-of-literature
#19
REVIEW
Seung Yeop Lee, Tae-Hwan Kim, Jae Keun Oh, Seung Jin Lee, Moon Soo Park
Degeneration of the intervertebral disc results in initial relative instability, hypermobility, and hypertrophy of the facet joints, particularly at the superior articular process. This finally leads to a reduction of the spinal canal dimensions and compression of the neural elements, which can result in neurogenic intermittent claudication caused by venous congestion and arterial hypertension around nerve roots. Most patients with symptomatic lumbar stenosis had neurogenic intermittent claudication with the risk of a fall...
October 2015: Asian Spine Journal
https://www.readbyqxmd.com/read/26378358/degenerative-cervical-myelopathy-a-spectrum-of-related-disorders-affecting-the-aging-spine
#20
REVIEW
Lindsay Tetreault, Christina L Goldstein, Paul Arnold, James Harrop, Alan Hilibrand, Aria Nouri, Michael G Fehlings
Cervical spinal cord dysfunction can result from either traumatic or nontraumatic causes, including tumors, infections, and degenerative changes. In this article, we review the range of degenerative spinal disorders resulting in progressive cervical spinal cord compression and propose the adoption of a new term, degenerative cervical myelopathy (DCM). DCM comprises both osteoarthritic changes to the spine, including spondylosis, disk herniation, and facet arthropathy (collectively referred to as cervical spondylotic myelopathy), and ligamentous aberrations such as ossification of the posterior longitudinal ligament and hypertrophy of the ligamentum flavum...
October 2015: Neurosurgery
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