keyword
MENU ▼
Read by QxMD icon Read
search

cordyceps sinensis

keyword
https://www.readbyqxmd.com/read/29792356/isochromanes-from-aspergillus-fumigatus-an-endophytic-fungus-from-cordyceps-sinensis
#1
Xiao-Hua Li, Xue-Hua Han, Ling-Ling Qin, Jun-Lin He, Zhi-Xing Cao, Yu-Cheng Gu, Da-Le Guo, Yun Deng
Four previously undescribed isochromanes were isolated from the fermentation broth of an endophytic fungus Aspergillus fumigatus, which was obtained from the fruiting body of Cordyceps sinensis. Their structures were elucidated through extensive spectroscopic analyses. One racemic isochromane was further purified by chiral HPLC to yield a pair of enantiomers and their absolute configurations were determined by quantum chemical ECD calculations. These isolated compounds were evaluated for cytotoxicity against two cell lines (MV4-11 and MDA-ME-231) and the result showed that compounds 1a and 2 exhibited moderate growth inhibition against MV4-11 cell line...
May 24, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29775778/the-genus-cordyceps-an-extensive-review-of-its-traditional-uses-phytochemistry-and-pharmacology
#2
REVIEW
Opeyemi Joshua Olatunji, Jian Tang, Adesola Tola, Florence Auberon, Omolara Oluwaniyi, Zhen Ouyang
The genus Cordyceps has about 750 identified species which are distributed in many regions of the World, but mainly found in South Asia, Europe and North America. The species of the genus are highly priced and are widely used as food and medicine for the treatment of various ailments. This present review compiles literature information on the ethno-medicinal, phytochemistry and pharmacological properties of species in the genus Cordyceps. In addition, the review also suggest recommendations for the future researches...
May 15, 2018: Fitoterapia
https://www.readbyqxmd.com/read/29754506/hirsutella-sinensis-inhibits-lewis-lung-cancer-via-tumor-microenvironment-effector-t-cells-in-mice
#3
Huiying Fu, Lu Jin, Xia Shao, Yuanyuan Li, Fangming Chen, Zhiqiang Shou, Xiaofang Tang, Bing Ji, Qiyang Shou
Hirsutella sinensis fungus (HSF) is an artificial substitute of the well-known medicine Cordyceps sinensis with similar beneficial effects in humans. We previously found that HSF can regulate immune function and inhibit tumor growth; however, the mechanisms involved in these effects were still unclear. Accordingly, in this study, we investigated the effects of HSF on immune cell subsets in the tumor microenvironment in mice. The results showed that HSF inhibited Lewis lung cancer growth, alleviated abnormalities in routine blood tests, and enhanced tumor-infiltrating T cells, particularly the proportion of effector CD8[Formula: see text] T cells...
May 13, 2018: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/29753871/combinatorial-usage-of-fungal-polysaccharides-from-cordyceps-sinensis-and-ganoderma-atrum-ameliorate-drug-induced-liver-injury-in-mice
#4
Songtao Fan, Xiaojun Huang, Sunan Wang, Chang Li, Zhihong Zhang, Mingyong Xie, Shaoping Nie
This study investigated the possible protective effect of combined fungal polysaccharides (CFP), consisting of Cordyceps sinensis polysaccharides (CSP) and Ganoderma atrum polysaccharides (PSG) with well-defined structural characteristics, against cyclophosphamide (CTX)-induced hepatotoxicity in mice. Our results indicated CFP effectively prevented the liver injury by decreasing toxicity markers (aspartate transaminase, alanine aminotransferase and alkaline phosphatase). Further biochemical and molecular analysis indicated CSP particularly inhibited the activation of Toll-like receptor 9 (TLR9) and its related inflammatory signals, including pro-inflammatory cytokines, inducible nitric oxide synthase, and cyclooxygenase-2 to modulate hepatic inflammation response...
May 10, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29752731/metabolomic-comparison-between-wild-ophiocordyceps-sinensis-and-artificial-cultured-cordyceps-militaris
#5
Lin Chen, Yuetao Liu, Qingfeng Guo, Qingxia Zheng, Wancun Zhang
In this study, a systematic research on the metabolome differences between wild Ophiocordyceps sinensis (O. sinensis) and artificial cultured Cordyceps militaris (C. militaris) was conducted using liquid chromatography-mass spectrometry. Principal components analysis (PCA) and Orthogonal projection on latent structure-discriminant analysis (OPLS-DA) results showed that C. militaris grown on solid rice medium (R-CM) and C. militaris grown on tussah pupa (T-CM) evidently separated and individually separated from wild O...
May 11, 2018: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29744278/proteomic-identification-of-marker-proteins-and-its-application-to-authenticate-ophiocordyceps-sinensis
#6
Xinxin Tong, Yixuan Wang, Zhengyao Xue, Lu Chen, Yi Qiu, Jing Cao, Cheng Peng, Jinlin Guo
Ophi o cordyceps sinensis ( O. sinensis ) is a highly valuable fungus because of its nutritious and medicinal properties. The objective of this study was to identify protein markers using a proteomics approach followed by the development of an immunoassay to authenticate O. sinensis . Four authentic O. sinensis samples collected from four production regions and four counterfeit samples were examined individually. Overall 22 characteristic proteins of O. sinensis were identified by two-dimensional electrophoresis (2-DE) coupled with the matrix-assisted laser desorption/ionization-time-of-light mass spectrometry (MALDI-TOF/MS)...
May 2018: 3 Biotech
https://www.readbyqxmd.com/read/29686726/hplc-icp-ms-speciation-analysis-and-risk-assessment-of-arsenic-in-cordyceps-sinensis
#7
Tian-Tian Zuo, Yao-Lei Li, Hong-Yu Jin, Fei Gao, Qi Wang, Ya-Dan Wang, Shuang-Cheng Ma
Background: Cordyceps sinensis , one of the most valued traditional herbal medicines in China, contains high amount of arsenic. Considering the adverse health effects of arsenic, this is of particular concern. The aim of this study was to determine and analyze arsenic speciation in C. sinensis , and to measure the associated human health risks. Methods: We used microwave extraction and high-performance liquid chromatography coupled with inductively coupled plasma mass spectrometry to determine and analyze the arsenic content in C...
2018: Chinese Medicine
https://www.readbyqxmd.com/read/29626602/protective-properties-of-combined-fungal-polysaccharides-from-cordyceps-sinensis-and-ganoderma-atrum-on-colon-immune-dysfunction
#8
Song-Tao Fan, Shao-Ping Nie, Xiao-Jun Huang, Sunan Wang, Jie-Lun Hu, Jun-Hua Xie, Qi-Xing Nie, Ming-Yong Xie
In vivo an ecological network of polysaccharides utilization by gut microbiota is not only an intense competition but also an impressive cooperation pattern. The present study evaluated the in vivo protective effect of combined fungal polysaccharides (CFP) from Cordyceps sinensis and Ganoderma atrum on colon immune dysfunction, induced by 150 mg/kg cyclophosphamide (CP). The results showed that C. sinensis polysaccharides (CSP) significantly promoted microbial-derived butyrate to improve histone h3 acetylation mediating regulatory T (Treg) cell specific Foxp3, as well as significantly restored CP-induced elevation of interleukin (IL)-17 and IL-21...
April 4, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29609095/a-comparative-proteomic-characterization-and-nutritional-assessment-of-naturally-and-artificially-cultivated-cordyceps-sinensis
#9
Xu Zhang, Qun Liu, Wei Zhou, Ping Li, Raphael N Alolga, Zhenming Qian, Wenjia Li, Lian-Wen Qi, Xiaojian Yin
Cordyceps sinensis has gained increasing attention due to its nutritional and medicinal properties. Herein, we employed label-free quantitative mass spectrometry to explore the proteome differences between naturally- and artificially-cultivated C. sinensis. A total of 22,829 peptides with confidence ≥95%, corresponding to 2541 protein groups were identified from the caterpillar bodies/stromata of 12 naturally- and artificially-cultivated samples of C. sinensis. Among them, 341 proteins showed significant differences between the samples of natural and artificial cultivation...
March 30, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29600609/-comparison-and-review-on-specifications-of-fermented-cordyceps-sinensis-products
#10
REVIEW
Ping Yang, Xiao-Xia Zhao, Yong-Wen Zhang
There are five kinds of fermented Cordyceps crude drug and their preparations that have been approved as medicine on the market. Since the initial strains of the crude drug were all isolated from natural Cordyceps sinensis, they have similar names, chemical components and even clinical applications. However, because of the different strain species and fermentation processes, there was significant difference in quality. As a result, they should be clearly distinguished in clinical use. Most of the products were researched and developed during the 1980s and 1990s, so there was difference in quality standards for different products, and their quality control levels of some products were not perfect...
February 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29568244/herbal-medicine-for-sports-a-review
#11
REVIEW
Maha Sellami, Olfa Slimeni, Andrzej Pokrywka, Goran Kuvačić, Lawrence D Hayes, Mirjana Milic, Johnny Padulo
The use of herbal medicinal products and supplements has increased during last decades. At present, some herbs are used to enhance muscle strength and body mass. Emergent evidence suggests that the health benefits from plants are attributed to their bioactive compounds such as Polyphenols, Terpenoids, and Alkaloids which have several physiological effects on the human body. At times, manufacturers launch numerous products with banned ingredient inside with inappropriate amounts or fake supplement inducing harmful side effect...
2018: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/29555964/publisher-correction-fungus-larva-relation-in-the-formation-of-cordyceps-sinensis-as-revealed-by-stable-carbon-isotope-analysis
#12
Lian-Xian Guo, Yue-Hui Hong, Qian-Zhi Zhou, Qing Zhu, Xiao-Ming Xu, Jiang-Hai Wang
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
March 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29481852/the-pharmacological-properties-of-ophiocordyceps-xuefengensis-revealed-by-transcriptome-analysis
#13
Jian Jin, Wenli Kang, Can Zhong, You Qin, Rongrong Zhou, Hao Liu, Jing Xie, Lin Chen, Yuhui Qin, Shuihan Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: The Yao ethnic group in Xuefeng Mountains area have used Xuefeng cordyceps, the caterpillar-fungus complex of Ophiocordyceps xuefengensis, for treating a variety of diseases for long. Just like some other cordyceps, O. xuefengensis, which is identified as the sister taxon of O. sinensis in 2013, also seems to have broad pharmacological properties, not only enhancing human immunity, anti-bacteria, anti-virus, but also anti-tumor. However, investigation of the medicinal fugal species O...
February 24, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29456676/-cordyceps-sinensis-inhibits-airway-remodeling-in-rats-with-chronic-obstructive-pulmonary-disease
#14
Lei Yang, Xingai Jiao, Jinxiang Wu, Jiping Zhao, Tian Liu, Jianfeng Xu, Xiaohui Ma, Liuzao Cao, Lin Liu, Yahui Liu, Jingyu Chi, Minfang Zou, Shuo Li, Jiawei Xu, Liang Dong
Cordyceps sinensis is a traditional Chinese herbal medicine that has been used for centuries in Asia as a tonic to soothe the lung for the treatment of respiratory diseases. The aim of the present study was to determine the effects of C. sinensi s on airway remodeling in chronic obstructive pulmonary disease (COPD) and investigate the underlying molecular mechanisms. Rats with COPD were orally administered C. sinensis at low, moderate or high doses (2.5, 5 or 7.5 g/kg/day, respectively) for 12 weeks. Airway tissue histopathology, lung inflammation and airway remodeling were evaluated...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29404841/a-multi-center-survey-on-dietary-knowledge-and-behavior-among-inpatients-in-oncology-department
#15
Minghua Cong, Jiejun Wang, Yu Fang, Yinghua Liu, Mingxiao Sun, Qiong Wu, Kan Wang, Yan Huang, Yiqun Ling, Yong Liu, Quanfu Li, Yibing Liu, Jiang Zhu, Lingjun Zhu, Zhendong Zheng, Ling Li, Dongying Liu, Zimin Liu, Hanping Shi, Peng Yuan
OBJECTIVE: To investigate the current associated factors of dietary knowledge and behavior, the intake and nutritional status in malignancy Chinese inpatients, and the malnutrition causes involved in dietary nutrition knowledge level and behavior, providing recommendations to patients for nutrition education and intervention. METHOD: Five hundred and thirty-five participants from 18 hospitals were investigated by a questionnaire related to dietary knowledge and behavior...
February 5, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29371523/entomopathogenicity-and-biological-attributes-of-himalayan-treasured-fungus-ophiocordyceps-sinensis-yarsagumba
#16
REVIEW
Bikash Baral
Members of the entomophagous fungi are considered very crucial in the fungal domain relative to their natural phenomenon and economic perspectives; however, inadequate knowledge of their mechanisms of interaction keeps them lagging behind in parallel studies of fungi associated with agro-ecology, forest pathology and medical biology. Ophiocordyceps sinensis (syn. Cordyceps sinensis ), an intricate fungus-caterpillar complex after it parasitizes the larva of the moth, is a highly prized medicinal fungus known widely for ages due to its peculiar biochemical assets...
February 5, 2017: Journal of Fungi (Basel, Switzerland)
https://www.readbyqxmd.com/read/29348077/effects-of-cordyceps-sinensis-on-macrophage-function-in-high-fat-diet-fed-rats-and-its-anti-proliferative-effects-on-imr-32-human-neuroblastoma-cells
#17
Leandro Freire Dos Santos, Rosalia Rubel, Sandro Jose Ribeiro Bonatto, Adriana Aya Yamaguchi, Maria Fernanda Torres, Vanete Thomaz Soccol, Andre Luís Lopes da Silva, Carlos Ricardo Soccol
Macrophages have been considered an elusive yet emerging therapeutic target in tumor development since they are an important component in tumor microenvironment. The purpose of the present study was to evaluate the effect of C. sinensis on macrophage function (a component of tumor microenvironment which can alter the virulence of cancer) in high-fat diet fed rats. IMR-32 human neuroblastoma cell cytotoxicity was also investigated. The following parameters were observed to evaluate macrophage function: superoxide anion, hydrogen peroxide, nitric oxide, lysosomal volume and phagocytic capacity...
January 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29339281/bifidogenic-effects-of-cordyceps-sinensis-fungal-exopolysaccharide-and-konjac-glucomannan-after-ultrasound-and-acid-degradation
#18
Ang-Xin Song, Yu-Heng Mao, Ka-Chai Siu, Jian-Yong Wu
The bifidogenic effects of exopolysaccharide (EPS) of a medicinal fungus (Cordyceps sinensis) and a well-known food polysaccharide konjac glucomannan (KGM) with different molecular weight (MW) ranges were evaluated through in vitro experiments in liquid cultures of Bifidobacteria. Native EPS and KGM were partially degraded with power ultrasound (US) to improve the water solubility, and further hydrolysed with trifluoroacetic acid to much lower MW. The acid-hydrolysed fractions (EPS-AH and KGM-AH) supported the growth of all five tested bifidobacterial species, while the US-degraded high MW fractions, EPS-US and KGM-US, could only slightly support the growth of some species...
May 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29243433/-comparative-study-on-specific-chromatograms-and-main-nucleosides-of-cultivated-and-wild-cordyceps-sinensis
#19
Ke Zan, Li-Li Huang, Li-Nong Guo, Jie Liu, Jian Zheng, Shuang-Cheng Ma, Zheng-Ming Qian, Wen-Jia Li
This study is to establish the HPLC specific chromatogram and determine four main nucleosides of wild and cultivated Cordyceps sinensis. Uridine, inosine, guanosine and adenosine were selected as reference substance. HPLC analysis was performed on a Waters XSelect HSS T3 C₁₈ (4.6 mm×250 mm, 5 μm), with a mobile phase consisting of water(A)-acetonitrile (B) at a flow rate of 0.6 mL•min⁻¹ (0-5 min,0% B;5-15 min,0%-10% B, 15-30 min,10%-20% B, 30-33 min, 20%-50% B, 33-35 min, 50%-0% B, 35-40 min, 0% B)...
October 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29199566/clinical-effects-of-a-commercial-supplement-of-ophiocordyceps-sinensis-and-ganoderma-lucidum-on-cognitive-function-of-healthy-young-volunteers
#20
Sharon Tsuk, Yarden Har Lev, Arie Rotstein, Rafi Carasso, Aviva Zeev, Yael Netz, Tzvi Dwolatski, Gilit Steiner
Ophiocordyceps sinensis (= Cordyceps sinensis) and Ganoderma lucidum are medicinal mushrooms used in traditional Chinese medicine. The effects of O. sinensis and G. lucidum on cognitive function have been evaluated through the use of animal models and in vitro studies, which indicated beneficial effects. The purpose of this study was to evaluate the effects of treatment with a commercially available supplement of O. sinensis and G. lucidum on cognitive function in young, healthy human participants. Physical education students (n = 96 [53 men, 43 women]; mean ± standard deviation age, 26...
2017: International Journal of Medicinal Mushrooms
keyword
keyword
114925
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"